PradiptaGhoshMD

PubMed

• 4 citations
  Regulation of DNA damage response by trimeric G-proteins.
  Amer Ali Abd El-Hafeez, Nina Sun, Anirban Chakraborty, Jason Ear, Suchismita Roy, Pranavi Chamarthi, Navin Rajapakse, Soumita Das, Kathryn E Luker, Tapas K Hazra, Gary...> ;Iscience. 2023 Feb 17
• 2 citations
  Design principles of improving the dose-response alignment in coupled GTPase switches.
  Lingxia Qiao, Pradipta Ghosh, Padmini Rangamani> ;NPJ Systems Biology and Applications. 2023 Jan 31
• 1 citations
  Artificial intelligence-guided discovery of gastric cancer continuum.
  Daniella Vo, Pradipta Ghosh, Debashis Sahoo> ;Gastric Cancer. 2023 Mar 1
• Identification of a novel gene signature for neuroblastoma differentiation using a Boolean implication network.
  Peter E Zage, Yuchen Huo, Divya Subramonian, Christophe Le Clorennec, Pradipta Ghosh, Debashis Sahoo> ;Genes, Chromosomes & Cancer. 2023 Jun 1
• 13 citations
  Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed withantitumor activity towards non-small lung cancer.
  Esraa A Abdelsalam, Amer Ali Abd El-Hafeez, Wagdy M Eldehna, Mahmoud A El Hassab, Hala Mohamed M Marzouk, Mahmoud M Elaasser, Nageh A Abou Taleb, Kamilia M Amin, Hatem...> ;Journal of Enzyme Inhibition and Medicinal Chemistry. 2022 Dec 1
• 12 citations
  2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights.
  Mostafa M Elbadawi, Wagdy M Eldehna, Amer Ali Abd El-Hafeez, Warda R Somaa, Amgad Albohy, Sara T Al-Rashood, Keli K Agama, Eslam B Elkaeed, Pradipta Ghosh, Yves Pommie...> ;Journal of Enzyme Inhibition and Medicinal Chemistry. 2022 Dec 1
• 12 citations
  New 1,2,3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization.
  Hamada H H Mohammed, Amer Ali Abd El-Hafeez, Kareem Ebeid, Aml I Mekkawy, Mohammed A S Abourehab, Emad I Wafa, Suhaila O Alhaj-Suliman, Aliasger K Salem, Pradipta Ghos...> ;Journal of Enzyme Inhibition and Medicinal Chemistry. 2022 Dec 1
• 6 citations
  Identification of novel piperazine-tethered phthalazines as selective CDK1 inhibitors endowed with in vitro anticancer activity toward the pancreatic cancer.
  Laila Akl, Amer Ali Abd El-Hafeez, Tamer M Ibrahim, Rofaida Salem, Hala Mohamed M Marzouk, Ramadan A El-Domany, Pradipta Ghosh, Wagdy M Eldehna, Sahar M Abou-Seri> ;European Journal of Medicinal Chemistry. 2022 Dec 5
• 5 citations
  COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis.
  Saptarshi Sinha, Vanessa Castillo, Celia R Espinoza, Courtney Tindle, Ayden G Fonseca, Jennifer M Dan, Gajanan D Katkar, Soumita Das, Debashis Sahoo, Pradipta Ghosh> ;Ebiomedicine. 2022 Aug 1
• 16 citations
  Effects of iron modulation on mesenchymal stem cell-induced drug resistance in estrogen receptor-positive breast cancer.
  Johanna M Buschhaus, Shrila Rajendran, Brock A Humphries, Alyssa C Cutter, Ayşe J Muñiz, Nicholas G Ciavattone, Alexander M Buschhaus, Tatiana Cañeque, Zeribe C Nwosu,...> ;Oncogene. 2022 Jul 1
• 9 citations
  The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients.
  Carlos G Gonzalez, Robert H Mills, Melissa C Kordahi, Marvic Carrillo-Terrazas, Henry Secaira-Morocho, Christella E Widjaja, Matthew S Tsai, Yash Mittal, Brian A Yee, ...> ;Cellular and Molecular Gastroenterology and Hepatology. 2022 Jan 1
• A predictive computational model reveals that GIV/Girdin serves as a tunable valve for EGFR-stimulated Cyclic AMP Signals.
  Getz, M.,Swanson, L.,Sahoo, D.,Ghosh, P.,Rangamani, P.> ;Mol. Biol. Cell. 2019 Apr 25
• Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3.
  Abd El-Hafeez, A. A.,Khalifa, H. O.,Mahdy, EAM.,Sharma, V.,Hosoi, T.,Ghosh, P.,Ozawa, K.,Montano, M. M.,Fujimura, T.,Ibrahim, ARN.,Abdelhamid, MAA.,Pack, S. P.,Shouman...> ;Pharmacol Rep. 2019 Mar 04
• Single-Cell Imaging of Metastatic Potential of Cancer Cells.
  Midde, K.,Sun, N.,Rohena, C.,Joosen, L.,Dhillon, H.,Ghosh, P.> ;iScience. 2018 Dec 01
• Convergence of Wnt, Growth Factor, and Heterotrimeric G Protein Signals on the Guanine Nucleotide Exchange Factor Daple
  Pradipta Ghosh, MD> ;Science Magazine. 2018 Mar 01
• A Daple-Akt feed-forward loop enhances noncanonical Wnt signals by compartmentalizing β-catenin.
  Aznar, N.,Sun, N.,Dunkel, Y.,Ear, J.,Buschman, M. D.,Ghosh, P.> ;Mol. Biol. Cell. 2017 Oct 13
• Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins.
  Lopez-Sanchez, I.,Kalogriopoulos, N.,Lo, I. C.,Kabir, F.,Midde, K. K.,Wang, H.,Ghosh, P.> ;Mol. Biol. Cell. 2015 Oct 09
• Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity.
  Ma, G. S.,Lopez-Sanchez, I.,Aznar, N.,Kalogriopoulos, N.,Pedram, S.,Midde, K.,Ciaraldi, T. P.,Henry, R. R.,Ghosh, P.> ;Mol. Biol. Cell. 2015 Sep 18
• GIV/girdin binds exocyst subunit-Exo70 and regulates exocytosis of GLUT4 storage vesicles.
  Lopez-Sanchez, I.,Ma, G. S.,Pedram, S.,Kalogriopoulos, N.,Ghosh, P.> ;Biochem. Biophys. Res. Commun.. 2015 Oct 31
• Cyclin-Dependent Kinase 5 Activates Guanine Nucleotide Exchange Factor GIV/Girdin to Orchestrate Migration–Proliferation Dichotomy
  Pradipta Ghosh, MD> ;Proceedings of the National Academy of Sciences. 2015 Aug 20
• GIV/Girdin Transmits Signals from Multiple Receptors by Triggering Trimeric G Protein Activation.
  Garcia-Marcos, M.,Ghosh, P.,Farquhar, M. G.> ;J. Biol. Chem.. 2015 Jan 22
• Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors.
  Midde, K. K.,Aznar, N.,Laederich, M. B.,Ma, G. S.,Kunkel, M. T.,Newton, A. C.,Ghosh, P.> ;Proc. Natl. Acad. Sci. U.S.A.. 2015 Feb 26
• Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin.
  Lin, C.,Ear, J.,Midde, K.,Lopez-Sanchez, I.,Aznar, N.,Garcia-Marcos, M.,Kufareva, I.,Abagyan, R.,Ghosh, P.> ;Mol. Biol. Cell. 2014 Sep 05
• Protein kinase C-theta (PKC?) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin.
  López-Sánchez, I.,Garcia-Marcos, M.,Mittal, Y.,Aznar, N.,Farquhar, M. G.,Ghosh, P.> ;Proc. Natl. Acad. Sci. U.S.A.. 2013 Apr 2
• A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate.
  Ghosh, P.,Beas, A. O.,Bornheimer, S. J.,Garcia-Marcos, M.,Forry, E. P.,Johannson, C.,Ear, J.,Jung, B. H.,Cabrera, B.,Carethers, J. M.,Farquhar, M. G.> ;Mol. Biol. Cell. 2010 May 14
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