RajKMaturiMD

Ophthalmology • Indianapolis, IN

Retinal Disease

Partner, Midwest Eye Institute

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Office
10300 N Illinois St, Suite 1060
Indianapolis, IN 46290
Phone+1 317-817-1414

Fax+1 317-805-4587
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Education & Training

Baylor College of Medicine/Cullen Eye InstituteResidency, Ophthalmology, 1994 - 1997
Baylor College of MedicineInternship, Transitional Year, 1993 - 1994
New York University School of MedicineClass of 1993

Certifications & Licensure

IN State Medical License 1999 - 2025
IA State Medical License 1997 - 2000
PA State Medical License 1997 - 1998
American Board of Ophthalmology Ophthalmology

Awards, Honors, & Recognition

Indianapolis Monthly Castle Connolly, 2013-2023
Fellow (FAAO) American Academy of Ophthalmology

Clinical Trials

Intravitreal Ranibizumab for Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy (N) Start of enrollment: 2010 Jun 01
Completed
Phase 2, Phase 3
Single Site, Masked, Randomized, Controlled Study to Assess Efficacy of Osurdex as Adjunct to Avastin Compared With Avastin Alone in the Treatment of Patients With Macular Edema Due to Central or Branch Retinal Vein Occlusion Start of enrollment: 2010 Mar 01
Completed
Phase 4
Ozurdex as Adjunct to Avastin Compared to Avastin Alone in Treatment of Patients With Diabetic Macular Edema Start of enrollment: 2011 Mar 01
Completed
Phase 4
Effect of Diabetes Education During Retinal Ophthalmology Visits on Diabetes Control Start of enrollment: 2011 Oct 01
Completed
Phase 3
Phase II Combination Steroid and Anti-VEGF for Persistent DME Start of enrollment: 2014 Feb 01
Completed
Phase 2
Anti-Vascular Endothelial Growth Factor (Anti-VEGF) Alone Versus Ozurdex Given Every 3 Months for Treatment of Persistent Diabetic Macular Edema Start of enrollment: 2014 Jan 01
Completed
Phase 4
A Phase I Single Ascending Dose Study of the Intravitreal Plasma Kallikrein Inhibitor KVD001 in Subjects With DME Start of enrollment: 2014 Jul 18
Completed
Phase 1
Sirolimus in Conjunction With Eylea vs Eylea Alone for Exudative AMD Start of enrollment: 2016 Apr 01
Completed
Phase 2
HORNBILL: A Study to Test Different Doses of BI 764524 in Patients Who Have Had Laser Treatment for a Type of Diabetic Eye Disease Called Diabetic Retinopathy With Diabetic Macular Ischemia Start of enrollment: 2020 Jun 12
Completed
Phase 1, Phase 2
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Publications & Presentations

PubMed

Risk Factors for Meeting Criteria for Switching from Bevacizumab to Aflibercept When Treating Eyes with Diabetic Macular Edema and Visual Acuity of < 20/40.
Danni Liu, Maureen G Maguire, Adam R Glassman, Lee M Jampol, Ronald M Kingsley, Daniel F Martin, Raj K Maturi, Gisela Velez, Jennifer K Sun, , Chirag D Jhaveri, Ruben ...> ;Ophthalmology. 2024 Feb 8
Clinical proof of concept for anti-FGF2 therapy in exudative age-related macular degeneration (nAMD): phase 2 trials in treatment-naïve and anti-VEGF pretreated patients.
Daniel S Pereira, Raj K Maturi, Kazumasa Akita, Vinaya Mahesh, Robert B Bhisitkul, Toshiaki Nishihata, Eri Sakota, Yusuf Ali, Emiko Nakamura, Padma Bezwada, Yoshikazu ...> ;Eye. 2024 Apr 1
Four-Year Visual Outcomes After Intravitreous Aflibercept for Vision-Threatening Complications of Diabetic Retinopathy-Reply.
Jennifer K Sun, Adam R Glassman, Raj K Maturi> ;JAMA. 2023 May 23
10 citations
Four-Year Visual Outcomes in the Protocol W Randomized Trial of Intravitreous Aflibercept for Prevention of Vision-Threatening Complications of Diabetic Retinopathy.
Raj K Maturi, Adam R Glassman, Kristin Josic, Carl W Baker, Adam T Gerstenblith, Lee M Jampol, Annal Meleth, Daniel F Martin, Michele Melia, Omar S Punjabi, Soraya Rof...> ;JAMA. 2023 Feb 7
Intravitreal sirolimus with adjunct aflibercept versus aflibercept monotherapy for persistent, exudative age-related macular degeneration: a pilot study.
Lucas W Rowe, Robert J Minturn, Lauren A Burgett, Peter Bracha, Raj K Maturi> ;International Journal of Retina and Vitreous. 2023 Jan 5
2 citations
Impact of Modifying Abicipar Manufacturing Process in Patients with Neovascular Age-Related Macular Degeneration: MAPLE Study Results.
David Callanan, Rahul N Khurana, Raj K Maturi, Sunil Patel, Charles C Wykoff, David Eichenbaum, Arshad M Khanani, Tarek Hassan, Hanh Badger, Shraddha Mehta, Grace Le, ...> ;Clinical Ophthalmology. 2023 Jan 1
1 citations
DEFINING "STRONG" VERSUS "WEAK" RESPONSE TO ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR TREATMENT FOR CENTER-INVOLVED DIABETIC MACULAR EDEMA.
Jennifer K Sun, Wesley T Beaulieu, Michele Melia, Frederick L Ferris 3rd, Raj K Maturi, Jared S Nielsen, Sharon D Solomon, Lee M Jampol> ;Retina. 2023 Apr 1
6 citations
A Phase I, Single Ascending Dose Study of GEM103 (Recombinant Human Complement Factor H) in Patients with Geographic Atrophy.
Arshad M Khanani, Raj K Maturi, Nika Bagheri, Benjamin Bakall, David S Boyer, Stephen S Couvillion, Dilsher S Dhoot, Nancy M Holekamp, Karim N Jamal, Dennis M Marcus, ...> ;Ophthalmology Science. 2022 Jun 1
2 citations
Advanced Meditation and Vegan Diet Increased Acylglycines and Reduced Lipids Associated with Improved Health: A Prospective Longitudinal Study.
Ramana V Vishnubhotla, Paul L Wood, Ashutosh Verma, John E Cebak, Sepideh Hariri, Mayur Mudigonda, Suresh Alankar, Raj Maturi, Hibiki Orui, Balachundhar Subramaniam, D...> ;Journal of Integrative and Complementary Medicine. 2022 Aug 1
3 citations
Corrigendum: Yoga, Meditation and Mind-Body Health: Increased BDNF, Cortisol Awakening Response, and Altered Inflammatory Marker Expression After a 3-Month Yoga and Me...
B Rael Cahn, Matthew S Goodman, Christine T Peterson, Raj Maturi, Paul J Mills> ;Frontiers in Human Neuroscience. 2022 Jan 1
21 citations
Large-scale genomic study reveals robust activation of the immune system following advanced Inner Engineering meditation retreat.
Vijayendran Chandran, Mei-Ling Bermúdez, Mert Koka, Brindha Chandran, Dhanashri Pawale, Ramana Vishnubhotla, Suresh Alankar, Raj Maturi, Balachundhar Subramaniam, Sent...> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Dec 21
9 citations
Phase 1 Study of THR-687, a Novel, Highly Potent Integrin Antagonist for the Treatment of Diabetic Macular Edema.
Arshad M Khanani, Sunil S Patel, Victor H Gonzalez, Suk J Moon, Glenn J Jaffe, John A Wells, Petra Kozma, Pravin U Dugel, Raj K Maturi> ;Ophthalmology Science. 2021 Sep 1
8 citations
Safety and Efficacy of Intravitreal Risuteganib for Non-Exudative AMD: A Multicenter, Phase 2a, Randomized, Clinical Trial.
David S. Boyer, Victor H. Gonzalez, Derek Y Kunimoto, Raj K Maturi, Richard H. Roe, Michael A Singer, Samantha Xavier, Julie Kornfield, Baruch D. Kuppermann, Hugo Quir...> ;Ophthalmic Surgery, Lasers & Imaging Retina. 2021 Jun 1
4 citations
Pneumatic Vitreolysis with Perfluoropropane for Vitreomacular Traction with and without Macular Hole: DRCR Retina Network Protocols AG and AH.
Clement K. Chan, Calvin E. Mein, Adam R. Glassman, Wesley T. Beaulieu, Claire T. Calhoun, Glenn J. Jaffe, Lee M. Jampol, Mathew W MacCumber, Maureen G. Maguire, Raj K....> ;Ophthalmology. 2021 May 11
63 citations
Effect of Intravitreous Anti-Vascular Endothelial Growth Factor vs Sham Treatment for Prevention of Vision-Threatening Complications of Diabetic Retinopathy: The Proto...
Raj K. Maturi, Adam R. Glassman, Kristin Josic, Andrew N. Antoszyk, Barbara A Blodi, Lee M. Jampol, Dennis M. Marcus, Daniel F. Martin, Michele Melia, Hani Salehi-Had,...> ;JAMA Ophthalmology. 2021 Jul 1
6 citations
Intravitreal sirolimus for persistent, exudative age-related macular degeneration: a Pilot Study.
Robert J. Minturn, Peter Bracha, Margaret J. Klein, Jay Chhablani, Ashley Harless, Raj K. Maturi> ;International Journal of Retina and Vitreous. 2021 Feb 16
11 citations
Isha Yoga Practices and Participation in Samyama Program are Associated with Reduced HbA1C and Systemic Inflammation, Improved Lipid Profile, and Short-Term and Sustai...
Senthilkumar Sadhasivam, Suresh Alankar, Raj K. Maturi, Amy E. Williams, Ramana V. Vishnubhotla, Sepideh Hariri, Mayur Mudigonda, Dhanashri Pawale, Sangeeth Dubbireddi...> ;Frontiers in Psychology. 2021 May 19
19 citations
Two-Year Results of the Phase 3 Randomized Controlled Study of Abicipar in Neovascular Age-Related Macular Degeneration.
Rahul N. Khurana, Derek Y Kunimoto, Young Hee Yoon, Charles C. Wykoff, Andrew Chang, Raj K. Maturi, Hansjürgen Agostini, Eric H Souied, David R. Chow, Andrew J. Lotery...> ;Ophthalmology. 2021 Jul 1
20 citations
Inner Engineering Practices and Advanced 4-day Isha Yoga Retreat Are Associated with Cannabimimetic Effects with Increased Endocannabinoids and Short-Term and Sustaine...
Senthilkumar Sadhasivam, Suresh Alankar, Raj K. Maturi, Ramana V. Vishnubhotla, Mayur Mudigonda, Dhanashri Pawale, Santhosshi Narayanan, Sepideh Hariri, Chithra Ram, T...> ;Evidence-Based Complementary and Alternative Medicine. 2020 Jun 5
59 citations
Efficacy and Safety of Abicipar in Neovascular Age-Related Macular Degeneration: 52-Week Results of Phase 3 Randomized Controlled Study.
Derek Y Kunimoto, Young Hee Yoon, Charles C. Wykoff, Andrew Chang, Rahul N. Khurana, Raj K. Maturi, Hansjürgen Agostini, Eric H Souied, David R. Chow, Andrew J. Lotery...> ;Ophthalmology. 2020 Apr 9
8 citations
Natural history of diabetic macular edema and factors predicting outcomes in sham-treated patients (MEAD study).
Young Hee Yoon, David S. Boyer, Raj K. Maturi, Francesco Bandello, Rubens Belfort, Albert J. Augustin, Xiao-yan Li, Zhanying Bai, Yehia Hashad> ;Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 2019 Oct 25
10 citations
One-Time Intravitreal Injection of KVD001, a Plasma Kallikrein Inhibitor, in Patients with Central-Involved Diabetic Macular Edema and Reduced Vision: An Open-Label Ph...
Jennifer K. Sun, Raj K. Maturi, David S. Boyer, John A. Wells, Victor H. Gonzalez, Robert Tansley, Helen Hernandez, Andreas Maetzel, Edward P. Feener, Lloyd Paul Aiello> ;Ophthalmology. Retina. 2019 Jul 26
19 citations
Evaluation of Abicipar Pegol (an Anti-VEGF DARPin Therapeutic) in Patients With Neovascular Age-Related Macular Degeneration: Studies in Japan and the United States
Derek Kunimoto, Masahito Ohji, Raj K Maturi, Tetsuju Sekiryu, Ying Wang, Grace Pan, Xiao-yan Li, Susan Schneider, Bamboo, Cypress Study Groups> ;Ophthalmic Surgery, Lasers & Imaging Retina. 2019 Feb 1
47 citations
Double-Masked, Randomized, Phase 2 Evaluation of Abicipar Pegol (an Anti-VEGF DARPin Therapeutic) in Neovascular Age-Related Macular Degeneration.
David Callanan, Derek Y Kunimoto, Raj K Maturi, Sunil S. Patel, Giovanni Staurenghi, Sebastian Wolf, Janet K. Cheetham, Hohman Thomas C, Kimmie Kim, Francisco J. López...> ;Journal of Ocular Pharmacology and Therapeutics. 2018 Dec 6
28 citations
Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema.
Lee M. Jampol, Adam R. Glassman, Danni Liu, Lloyd Paul Aiello, Neil M. Bressler, Elia J. Duh, Susan E. Quaggin, John A. Wells, Charles C. Wykoff, David J. Browning, An...> ;Ophthalmology. 2018 Mar 7
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Authored Content

A Randomized Trial of Intravitreous Anti-VEGF for Prevention of Vision Threatening Complications of Diabetic Retinopathy (Protocol W)May 2021

Press Mentions

Early Anti-VEGF Treatment of Diabetic Retinopathy Doesn’t Improve Visual AcuityFebruary 13th, 2023
Preventive Value of Aflibercept Questioned in NPDR Without CI-DMEFebruary 8th, 2023
No Visual Acuity Benefit with Early Anti-VEGF for Diabetic RetinopathyFebruary 7th, 2023
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