RalphHrubanMD

PubMed

• Distinctive Pathology Associated With Focal Stenosis of the Main Pancreatic Duct Secondary to Remote Trauma: A Long-term Complication of Seat Belt Pancreatitis.
  Annie A Wu, Elizabeth D Thompson, John L Cameron, Jin He, Richard A Burkhart, William R Burns, Kelly J Lafaro, Christopher R Shubert, Marcia I Canto, Elliot K Fishman,...> ;The American Journal of Surgical Pathology. 2024 Mar 14
• Precursor lesions in familial and hereditary pancreatic cancer.
  Pflüger, M., Brosens, L., Hruban, R.> ;Familial Cancer. 2024 Feb 6
• Islands of genomic stability in the face of genetically unstable metastatic cancer.
  Bowland, K., Lai, J., Skaist, A., Zhang, Y., Teh, S., Roberts, N., Thompson, E., Wheelan, S., Karchin, R., Hruban, R., Iacobuzio-Donahue, C., Eshleman, J.> ;Biorxiv. 2024 Jan 29
• Machine learning to detect the SINEs of cancer.
  Douville, C., Lahouel, K., Kuo, A., Grant, H., Avigdor, B., Curtis, S., Summers, M., Cohen, J., Wang, Y., Mattox, A., Dudley, J., Dobbyn, L., Popoli, M., Ptak, J., Neh...> ;Science Translational Medicine. 2024 Jan 24
• 1 citations
  A mucus production programme promotes classical pancreatic ductal adenocarcinoma.
  Claudia Tonelli, Georgi N Yordanov, Yuan Hao, Astrid Deschênes, Juliene Hinds, Pascal Belleau, Olaf Klingbeil, Erin Brosnan, Abhishek Doshi, Youngkyu Park, Ralph H Hru...> ;Gut. 2024 Jan 23
• MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression.
  Chen, J., Zheng, Q., Hicks, J., Trabzonlu, L., Ozbek, B., Jones, T., Vaghasia, A., Larman, T., Wang, R., Markowski, M., Denmeade, S., Pienta, K., Hruban, R., Antonarak...> ;JCI Insight. 2023 Dec 22
• Deep neural network-based segmentation of normal and abnormal pancreas on abdominal CT: evaluation of global and local accuracies.
  Zhu, Z., Javed, A., Kinny-Köster, B., Kinzler, K., Fouladi, D., Blanco, A., Shayesteh, S., Kawamoto, S., Chu, L., Wolfgang, C., Hruban, R., Fishman, E.> ;Abdominal Radiology. 2024 Feb 1
• Three-dimensional assessments are necessary to determine the true, spatially-resolved composition of tissues.
  André Forjaz, Eduarda Vaz, Valentina Matos Romero, Saurabh Joshi, Alicia M Braxton, Ann C Jiang, Kohei Fujikura, Toby Cornish, Seung-Mo Hong, Ralph H Hruban, Pei-Hsun ...> ;Biorxiv. 2024 Mar 28
• Power-law growth models explain incidences and sizes of pancreatic cancer precursor lesions and confirm spatial genomic findings.
  Ashley L Kiemen, Pei-Hsun Wu, Alicia M Braxton, Toby C Cornish, Ralph H Hruban, Laura Wood, Denis Wirtz, David Zwicker> ;Biorxiv. 2023 Dec 4
• Detection of Pancreatic Ductal Adenocarcinoma-Associated Proteins in Serum.
  T Mamie Lih, Liwei Cao, Parham Minoo, Gilbert S Omenn, Ralph H Hruban, Daniel W Chan, Oliver F Bathe, Hui Zhang> ;Molecular & Cellular Proteomics. 2024 Jan 1
• CRISPR-Cas9 for selective targeting of somatic mutations in pancreatic cancers.
  Selina Shiqing K Teh, Kirsten Bowland, Alexis Bennett, Eitan Halper-Stromberg, Alyza Skaist, Jacqueline Tang, Fidel Cai, Antonella Macoretta, Hong Liang, Hirohiko Kami...> ;Biorxiv. 2023 Oct 10
• A deep learning model to triage and predict adenocarcinoma on pancreas cytology whole slide imaging.
  Andrew Sohn, Daniel Miller, Efrain Ribeiro, Nakul Shankar, Syed Ali, Ralph Hruban, Alexander Baras> ;Scientific Reports. 2023 Oct 2
• Three-dimensional analysis of ductular reactions and their correlation with liver regeneration and fibrosis.
  Tadashi Yoshizawa, Jae W Lee, Seung-Mo Hong, DongJun Jung, Michaël Noë, Wojciech Zbijewski, Ashley Kiemen, Pei-Hsun Wu, Denis Wirtz, Ralph H Hruban, Laura D Wood, Kiyo...> ;Virchows Archiv. 2023 Sep 14
• 4 citations
  Accurate non-invasive grading of nonfunctional pancreatic neuroendocrine tumors with a CT derived radiomics signature.
  Ammar A Javed, Zhuotun Zhu, Benedict Kinny-Köster, Joseph R Habib, Satomi Kawamoto, Ralph H Hruban, Elliot K Fishman, Christopher L Wolfgang, Jin He, Linda C Chu> ;Diagnostic and Interventional Imaging. 2024 Jan 1
• 4 citations
  The Origin of Highly Elevated Cell-Free DNA in Healthy Individuals and Patients with Pancreatic, Colorectal, Lung, or Ovarian Cancer.
  Austin K Mattox, Christopher Douville, Yuxuan Wang, Maria Popoli, Janine Ptak, Natalie Silliman, Lisa Dobbyn, Joy Schaefer, Steve Lu, Alexander H Pearlman, Joshua D Co...> ;Cancer Discovery. 2023 Oct 5
• Radiologists' Expectations of Artificial Intelligence in Pancreatic Cancer Imaging: How Good Is Good Enough?
  Linda C Chu, Taha Ahmed, Alejandra Blanco, Ammar Javed, Edmund M Weisberg, Satomi Kawamoto, Ralph H Hruban, Kenneth W Kinzler, Bert Vogelstein, Elliot K Fishman> ;Journal of Computer Assisted Tomography. 2023 Jul 28
• Radiologists' Expectations of Artificial Intelligence in Pancreatic Cancer Imaging: How Good Is Good Enough?
  Linda C Chu, Taha Ahmed, Alejandra Blanco, Ammar Javed, Edmund M Weisberg, Satomi Kawamoto, Ralph H Hruban, Kenneth W Kinzler, Bert Vogelstein, Elliot K Fishman> ;Journal of Computer Assisted Tomography. 2023 Jul 28
• 2 citations
  Somatic loss of ATM is a late event in pancreatic tumorigenesis.
  Raymond M Paranal, Zhengdong Jiang, Danielle Hutchings, Valentyna Kryklyva, Christian Gauthier, Kohei Fujikura, Neha Nanda, Bo Huang, Michael Skaro, Christopher L Wolf...> ;The Journal of Pathology. 2023 Aug 1
• 2 citations
  A Combined DNA/RNA-based Next-Generation Sequencing Platform to Improve the Classification of Pancreatic Cysts and Early Detection of Pancreatic Cancer Arising From Pa...
  Marina N Nikiforova, Abigail I Wald, Daniel M Spagnolo, Melissa A Melan, Maria Grupillo, Yi-Tak Lai, Randall E Brand, Anne Marie O'Broin-Lennon, Kevin McGrath, Walter ...> ;Annals of Surgery. 2023 Oct 1
• 1 citations
  Screening for pancreatic cancer has the potential to save lives, but is it practical?
  Jae W Lee, Nicholas J Roberts, Linda C Chu, Anne Marie Lennon, Alison P Klein, James R Eshleman, Elliot K Fishman, Marcia Irene Canto, Michael G Goggins, Ralph H Hruba...> ;Expert Review of Gastroenterology & Hepatology. 2023 Jul 3
• Mechanism of delayed cell death following simultaneous CRISPR-Cas9 targeting in pancreatic cancers.
  Selina Shiqing K Teh, Eitan Halper-Stromberg, Laura Morsberger, Alexis Bennett, Kirsten Bowland, Alyza Skaist, Fidel Cai, Hong Liang, Ralph H Hruban, Nicholas J Robert...> ;Biorxiv. 2023 Apr 5
• 4 citations
  Comprehensive DNA Methylation Analysis Indicates That Pancreatic Intraepithelial Neoplasia Lesions Are Acinar-Derived and Epigenetically Primed for Carcinogenesis.
  Emily K W Lo, Brian M Mears, H Carlo Maurer, Adrian Idrizi, Kasper D Hansen, Elizabeth D Thompson, Ralph H Hruban, Kenneth P Olive, Andrew P Feinberg> ;Cancer Research. 2023 Jun 2
• 5 citations
  A primer on artificial intelligence in pancreatic imaging.
  Taha M Ahmed, Satomi Kawamoto, Ralph H Hruban, Elliot K Fishman, Philippe Soyer, Linda C Chu> ;Diagnostic and Interventional Imaging. 2023 Sep 1
• 1 citations
  MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression.
  Jiayu Chen, Qizhi Zheng, Jessica L Hicks, Levent Trabzonlu, Busra Ozbek, Tracy Jones, Ajay Vaghasia, Tatianna C Larman, Rulin Wang, Mark C Markowski, Sam R Denmeade, K...> ;Biorxiv. 2023 Mar 10
• 3 citations
  RNA Sequencing Identifies Frequent Mitogen-activated Protein Kinase-associated Fusion Genes in Intraductal Tubulopapillary Neoplasms of the Pancreas.
  Jae W Lee, Ralph H Hruban, Lodewijk A A Brosens, Vincenzo Condello, Marina N Nikiforova, Aatur D Singhi> ;Gastroenterology. 2023 Jun 1
• Join now to see all

Journal Articles

• Pancreatic Cancer Arising in the Remnant Pancreas Is Not Always a Relapse of the Preceding Primary  
  John L Cameron, Christopher L Wolfgang, Jin He, Matthew J Weiss, Ralph H Hruban, Michael Goggins, Nature
• Single‐Cell Sequencing Defines Genetic Heterogeneity in Pancreatic Cancer Precursor Lesions  
  Kevin Waters, Jin He, Christopher L Wolfgang, Ralph H Hruban, Michael G Goggins, Matthew J Weiss, Justin Poling, The Journal of Pathology
• Implications of the Pattern of Disease Recurrence on Survival Following Pancreatectomy for Pancreatic Ductal Adenocarcinoma  
  Jin He, Ammar A Javed, John L Cameron, Alex B Blair, Elliot K Fishman, Matthew J Weiss, Ralph H Hruban, Christopher L Wolfgang, Annals of Surgical Oncology
• Whole-Exome Sequencing of Duodenal Neuroendocrine Tumors in Patients with Neurofibromatosis Type 1  
  Feriyl Bhaijee, Yi Ning, Ralph H Hruban, Nature
• Join now to see all

Other

• Molecular pathogenesis of exocrine pancreatic cancer 
  Hruban RH
  http://www.uptodate.com/contents/molecular-pathogenesis-of-exocrine-pancreatic-cancer
  UpToDate, Wolters Kluwer Health - 2013-04-16