RaymondYu JeangWangMD
Medical Genetics • Orange, CAClinical Biochemical Genetics, Clinical Genetics
Associate Clinical Professor, Pediatrics, University of California, Irvine College of Medicine
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Office
1201 W La Veta Blvd
Orange, CA 92868Phone+1 714-509-8852Fax+1 714-509-4531- Is this information wrong?
Summary
- I am the director of multidisciplinary lysosomal storage disorder program at CHOC Children’s and a board certified clinical geneticist and biochemical genetics specialist.
Education & Training
Cedars-Sinai Medical CenterFellowship, Medical Genetics and Genomics, 2006 - 2007- Cedars-Sinai Medical CenterResidency, Pediatrics, 2001 - 2006
David Geffen School of Medicine at UCLAClass of 2001
Certifications & Licensure
CA State Medical License 2002 - 2024- American Board of Medical Genetics and Genomics Clinical Biochemical Genetics
- American Board of Medical Genetics and Genomics Clinical Genetics and Genomics
Clinical Trials
- RGX-111 Gene Therapy in Patients With MPS I Start of enrollment: 2019 Apr 03
- Longitudinal Assessment of Atypical Tripeptidyl Peptidase 1 Enzyme Deficiency Patients Start of enrollment: 2019 Nov 01
- A Safety and Efficacy Study of LYS-GM101 Gene Therapy in Patients With GM1 Gangliosidosis Start of enrollment: 2021 May 11
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Publications & Presentations
PubMed
- Base editing corrects the common Salla diseasec.115C>T variant.Jerry F Harb, Chloe L Christensen, Shih-Hsin Kan, Allisandra K Rha, Perla Andrade-Heckman, Laura Pollard, Richard Steet, Jeffrey Y Huang, Raymond Y Wang> ;Molecular Therapy. Nucleic Acids. 2023 Dec 12
- 1 citationsGrowth patterns in patients with mucopolysaccharidosis VII.Adriana M Montaño, Agnieszka Różdżyńska-Świątkowska, Agnieszka Jurecka, Antonio Nino Ramirez, Lin Zhang, Deborah Marsden, Raymond Y Wang, Paul Harmatz> ;Molecular Genetics and Metabolism Reports. 2023 Sep 1
- Generation of two induced pluripotent stem cell lines (CHOCi002-A and CHOCi003-A) from Pompe disease patients with compound heterozygous mutations in the GAA gene.Chloe Christensen, Perla Heckman, Allisandra Rha, Shih-Hsin Kan, Jerry Harb, Raymond Wang> ;Stem Cell Research. 2023 Jun 1
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Press Mentions
Gene Therapy in Children with MPS I Showing PromiseMarch 8th, 2023- UCI Earns Designation as CIRM Alpha Clinic with Five-Year, $8 Million GrantOctober 27th, 2022
- Lysogene Provides Additional Update on AAVance Phase 2/3 Gene Therapy Clinical Trial with LYS-SAF302 in Children with MPS IIIAJuly 7th, 2022
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Grant Support
- Combination Gene Therapy for Treatment of Canine Mucopolysaccharidosis Type IEunice Kennedy Shriver National Institute of Child Health and Human Development2023–2028
- Alpha Stem Cell ClinicCalifornia Institute of Regenerative Medicine2023–2028
- Stable therapy in Pompe disease through genome editingNational Institute of Arthritis and Musculoskeletal and Skin Disease2021–2026
Committees
- Member, CalOptima Pharmacy and Therapeutics Committee 2018 - Present
- Member, CHOC Clinical Efficacy and Efficiency Committee 2018 - Present
Research History
- Principal InvestigatorAs PI of the Campbell Foundation of Caring Laboratory, I supervise efforts to develop CRISPR-based gene editing methods for generation of model systems and therapies for inherited lysosomal storage disorders.2017 - Present
Professional Memberships
- Member
- Society of Inherited Metabolic DiseaseMember
- Society for the Study of Inborn Errors of MetabolismMember
- American Society of Cell and Gene TherapyMember
Hospital Affiliations
Providence St. Joseph Hospital OrangeOrange, California
Children’s Health Orange County (CHOC)Orange, California
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