RichardKBurtMD

Internal Medicine • Chicago, IL

Adult Clinical & Laboratory Immunology, Hospital Medicine/Hospitalist, Hematology/Oncology

Professor and Chief, Division of Medicine-Immunotherapy for Autoimmune Diseases, Northwestern University Medical School

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Office
446 E Ontario
10th floor suite 1000
Chicago, IL 60611
Phone+1 312-695-4960

Fax+1 312-695-4961
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Education & Training

National Institutes of Health Clinical CenterFellowship, Hematology and Medical Oncology, 1991 - 1993
National Institutes of Health Clinical CenterFellowship, Hematology and Medical Oncology, 1990 - 1991
Baylor College of MedicineResidency, Internal Medicine, 1985 - 1988
Spectrum Health/Michigan State UniversityInternship, Internal Medicine, 1984 - 1985
Saint Louis University School of MedicineClass of 1984

Certifications & Licensure

IL State Medical License 1994 - 2026
UT State Medical License 2020 - 2024
CA State Medical License 2020 - 2024
MD State Medical License 1987 - 1996
MI State Medical License Active through 1985
American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

Top 10 Clinical Research Award: Distinguished Clinical Research Award Clinical Research Forum, 2020
America's Top Doctors Castle Connolly, 2003-2020
EBMT Van Bekkum Award European Society for Blood and Marrow Transplantation, 2018
Scientific America 50 Scientific American, 2006
Compassionate Care Physician of The Year award The Women's Board of Northwestern Memorial Hospital, 1999
Chicago Magazine: Top Doctors Castle Connolly, 2004, 2006, 2008, 2010, 2012, 2014
Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2011
America's Top Doctors for Cancer Castle Connolly, 2005-2008
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Clinical Trials

Phase I Study of High-Dose Cyclophosphamide and Total Body Irradiation With T Lymphocyte-Depleted Autologous Peripheral Blood Stem Cell or Bone Marrow Rescue in Patients With Multiple Sclerosis Start of enrollment: 2001 Apr 01
Completed
Phase 1
Study of Allogeneic Bone Marrow and T-Cell Depleted, CD34+ Peripheral Blood Stem Cell Transplantation in Patients With Aplastic Anemia Start of enrollment: 2001 Apr 01
Unknown status
Not Applicable
Lupus Immunosuppressive/Immunomodulatory Therapy or Stem Cell Transplant (LIST) Start of enrollment: 2005 Sep 01
Withdrawn
Phase 2
Immune Ablation and Hematopoietic Stem Cell Support in Patients With Systemic Lupus Erythematosus: A Phase II Study Start of enrollment: 2002 Sep 01
Completed
Phase 2
Stem Cell Therapy for Patients With Multiple Sclerosis Failing Alternate Approved Therapy- A Randomized Study Start of enrollment: 2005 Nov 16
Completed
Phase 2
Hematopoietic Stem Cell Transplantation in Autoimmune-Related Retinopathy(ARRON) Start of enrollment: 2004 Aug 01
Terminated
Phase 1
Hematopoietic Stem Cell Support in Vasculitis Start of enrollment: 2003 Aug 01
Terminated
Phase 1
Cyclophosphamide and rATG With Hematopoietic Stem Cell Support in Systemic Scleroderma Start of enrollment: 2005 Sep 01
Completed
Phase 2
Cyclophosphamide and Rabbit Antithymocyte Globulin (rATG)/Rituximab in Patients With Systemic Lupus Erythematosus Start of enrollment: 2005 Sep 23
Completed
Phase 2
Stem Cell Support in Patients With Rheumatoid Arthritis Start of enrollment: 1997 Jun 01
Terminated
Phase 1
Stem Cell Transplantation in Idiopathic Inflammatory Myopathy Diseases Start of enrollment: 2005 Sep 01
Terminated
Phase 1
Allogeneic Stem Cell Transplantation in Systemic Lupus Erythematosus Start of enrollment: 2004 Jul 01
Withdrawn
Phase 1
Hematopoietic Stem Cell Transplantation in Patients With Antiphospholipid Syndrome Start of enrollment: 2005 Aug 01
Withdrawn
Phase 1
Hematopoietic Stem Cell Transplantation in Chronic Inflammatory Demyelinating Polyneuropathy Start of enrollment: 2005 Feb 21
Completed
Phase 2
Hematopoietic Stem Cell Support in Patients With Autoimmune Bullous Skin Disorders Start of enrollment: 2002 Sep 01
Terminated
Phase 1
Hematopoietic Stem Cell Therapy for Patients With Multiple Sclerosis Start of enrollment: 2003 Jun 01
Terminated
Phase 1, Phase 2
Rheumatoid Arthritis:Tolerance Induction by Mixed Chimerism Start of enrollment: 2002 Sep 01
Terminated
Phase 1
Allogeneic Hematopoietic Stem Cell Transplantation (NST) for Patients With Systemic Sclerosis Start of enrollment: 2005 May 01
Terminated
Phase 1
Hematopoietic Stem Cell Support in Patients With Refractory Sarcoidosis Start of enrollment: 2003 Dec 01
Terminated
Phase 1, Phase 2
Stem Cell Transplantation in Patients With Primary Biliary Cirrhosis Start of enrollment: 2006 Jan 01
Withdrawn
Phase 1
Hematopoietic Stem Cell Therapy for Patients With Refractory Myasthenia Gravis Start of enrollment: 2002 Feb 01
Terminated
Phase 1
HLA-Identical Sibling Renal Transplant Tolerance Start of enrollment: 2007 Jul 01
Active, not recruiting
Not Applicable
Hematopoietic Stem Cell Transplant in Devic's Disease Start of enrollment: 2009 Oct 10
Completed
Phase 1, Phase 2
Efficacy and Safety of Umbilical Cord Blood Injection for Critical Limb Ischemia Start of enrollment: 2009 Nov 01
Terminated
Phase 1
Hematopoietic Stem Cell Support Versus Insulin in T1D Start of enrollment: 2009 Jan 01
Withdrawn
Phase 1, Phase 2
Non-myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (NST) for Patients With Refractory Crohn's Disease Start of enrollment: 2010 Jan 01
Terminated
Phase 1, Phase 2
Autologous Stem Cell Systemic Sclerosis Immune Suppression Trial Start of enrollment: 2011 Sep 15
Terminated
Phase 3
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Publications & Presentations

PubMed

20 citations
Real-world application of autologous hematopoietic stem cell transplantation in 507 patients with multiple sclerosis.
Richard K. Burt, Xiaoqiang Han, Kathleen Quigley, Irene Helenowski, Roumen Balabanov> ;Journal of Neurology. 2021 Oct 11
6 citations
Long term outcomes of the French ASTIS systemic sclerosis cohort using the global rank composite score.
Nassim Ait Abdallah, Mianbo Wang, Pauline Lansiaux, Mathieu Puyade, Sabine Berthier, Louis Terriou, Catney Charles, Richard K. Burt, Marie Hudson, Dominique Farge> ;Bone Marrow Transplantation. 2021 Jun 9
14 citations
New autoimmune diseases after autologous hematopoietic stem cell transplantation for multiple sclerosis.
Richard K. Burt, Paolo A. Muraro, Dominique Farge, Maria Carolina Oliveira, John A. Snowden, Riccardo Saccardi, Xiaoqiang Han, Kathleen Quigley, Valquiria Bueno, Danie...> ;Bone Marrow Transplantation. 2021 Apr 28
20 citations
Cardiac safe hematopoietic stem cell transplantation for systemic sclerosis with poor cardiac function: a pilot safety study that decreases neutropenic interval to 5 d...
Richard K. Burt, Xiaoqiang Han, Kathleen Quigley, Indira Arnautovic, Sanjiv J. Shah, Daniel C. Lee, Benjamin H. Freed, Borko Jovanovic, Irene Helenowski> ;Bone Marrow Transplantation. 2021 Jan 1
10 citations
The Cost Effectiveness of Immunoglobulin vs. Hematopoietic Stem Cell Transplantation for CIDP.
Richard K. Burt, Paul Tappenden, Roumen Balabanov, Xiaoqiang Han, Kathleen Quigley, John A. Snowden, Basil Sharrack> ;Frontiers in Neurology. 2021 Mar 22
14 citations
Autologous Hematopoietic Stem Cell Transplantation for Stiff-Person Spectrum Disorder: A Clinical Trial.
Richard K. Burt, Roumen Balabanov, Xiaoqiang Han, Kathleen Quigley, Indira Arnautovic, Irene Helenowski, John W. Rose, Teepu Siddique> ;Neurology. 2020 Dec 14
4 citations
Medical, ethical, and legal aspects of hematopoietic stem cell transplantation for Crohn’s disease in Brazil
Milton Artur Ruiz, Roberto Luiz Kaiser Junior, Lilian Piron-Ruiz, Priscila Samara Saran, Lilian Castiglioni, Luiz Gustavo de Quadros, Tainara Souza Pinho, Richard K. Burt> ;World Journal of Stem Cells. 2020 Oct 26
13 citations
Health economics and patient outcomes of hematopoietic stem cell transplantation versus disease-modifying therapies for relapsing remitting multiple sclerosis in the U...
Richard K. Burt, Paul Tappenden, Xiaoqiang Han, Kathleen Quigley, Indira Arnautovic, Basil Sharrack, John A. Snowden, Daniel M. Hartung> ;Multiple Sclerosis and Related Disorders. 2020 Oct 1
23 citations
Hematopoietic stem cell transplantation for chronic inflammatory demyelinating polyradiculoneuropathy.
Richard K. Burt, Roumen Balabanov, Jinny Tavee, Xiaoqiang Han, Robert L. Sufit, Senda Ajroud-Driss, Borko Jovanovic, Kathleen Quigley, Indira Arnautovic, Irene Helenow...> ;Journal of Neurology. 2020 Jun 27
9 citations
A pilot feasibility study of non-myeloablative allogeneic hematopoietic stem cell transplantation for refractory Crohn Disease
Richard K. Burt, Robert M. Craig, Laura Yun, Amy L. Halverson, Kathleen Quigley, Indira Arnautovic, Xiaoqiang Han> ;Bone Marrow Transplantation. 2020 May 28
17 citations
Type-1 Interferon Responses Underlie Tumor-Selective Replication of Oncolytic Measles Virus
Sarah Aref, Anna Castleton, Katharine Bailey, Richard K. Burt, Aditi Dey, Daniel Leongamornlert, Rachel J. Mitchell, Dina Ahmed Said Aly Okasha, Adele K. Fielding> ;Molecular Therapy. 2020 Apr 8
51 citations
Autologous nonmyeloablative hematopoietic stem cell transplantation for neuromyelitis optica
Richard K. Burt, Roumen Balabanov, Xiaoqiang Han, Carol Ann Burns, Joseph Gastala, Borko Jovanovic, Irene Helenowski, Jiraporn Jitprapaikulsan, James P. Fryer, Sean J....> ;Neurology. 2019 Oct 29
133 citations
Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress.
Richard K. Burt, Aditi Dey, Sarah Aref, Melanie Aguiar, Ayse U. Akarca, Katharine Bailey, William Day, Steven Hooper, Amy A Kirkwood, Kristina Kirschner, SooWah Lee, C...> ;Blood. 2019 Oct 24
169 citations
Effect of Nonmyeloablative Hematopoietic Stem Cell Transplantation vs Continued Disease-Modifying Therapy on Disease Progression in Patients With Relapsing-Remitting M...
Richard K. Burt, Roumen Balabanov, Joachim Burman, Basil Sharrack, John A. Snowden, Maria Carolina Oliveira, Jan Fagius, John W. Rose, Flavia Nelson, Amilton Antunes B...> ;JAMA. 2019 Jan 15
22 citations
Blinatumomab, a bispecific B-cell and T-cell engaging antibody, in the treatment of B-cell malignancies
Richard K. Burt, Dana Warcel, Adele K. Fielding> ;Human Vaccines & Immunotherapeutics. 2019 Jan 1
18 citations
Five year follow-up after autologous peripheral blood hematopoietic stem cell transplantation for refractory, chronic, corticosteroid-dependent systemic lupus erythema...
Richard K. Burt, Xiaoqiang Han, Paula Gozdziak, Kim Yaung, Amy Morgan, Allison M. Clendenan, Jacquelyn Henry, Michelle A. Calvario, Syamal K. Datta, Irene Helenowski, ...> ;Bone Marrow Transplantation. 2018 May 31
24 citations
Systemic sclerosis: Autologous HSCT is efficacious, but can we make it safer?
Richard K. Burt, Dominique Farge> ;Nature Reviews. Rheumatology. 2018 Mar 8
21 citations
Autologous haematopoietic stem cell transplantation as a first-line disease-modifying therapy in patients with ‘aggressive’ multiple sclerosis:
J Das, John A. Snowden, Joachim Burman, Mark S. Freedman, Harold L. Atkins, Marjorie Bowman, Richard K. Burt, Riccardo Saccardi, C Innocenti, S Mistry, P J Laud, Helen...> ;Multiple Sclerosis. 2021 Feb 10
Blogs cannot separate wheat from chaff
Richard K. Burt, John A. Snowden, Joachim Burman, Maria Carolina Oliveira, Basil Sharrack> ;Science. 2017 Nov 3
13 citations
Low toxicity and favorable clinical and quality of life impact after non-myeloablative autologous hematopoietic stem cell transplant in Crohn's disease.
Milton Artur Ruiz, Roberto Luiz Kaiser, Luiz Gustavo de Quadros, Lilian Piron-Ruiz, Tatiana Peña-Arciniegas, Mikaell Alexandre Gouvea Faria, Rubens Camargo Siqueira, F...> ;BMC Research Notes. 2017 Oct 6
74 citations
Cardiopulmonary assessment of patients with systemic sclerosis for hematopoietic stem cell transplantation: recommendations from the European Society for Blood and Mar...
Dominique Farge, Richard K. Burt, M-C Oliveira, Elie Mousseaux, Montserrat Rovira, Zora Marjanovic, J.K. de Vries-Bouwstra, N. Del Papa, Riccardo Saccardi, Sanjiv J. S...> ;Bone Marrow Transplantation. 2017 May 22
3 citations
Stem-cell transplantation for Crohn's disease: same authors, different conclusions?
Richard K. Burt, Roberto Luiz Kaiser, Milton Artur Ruiz> ;The Lancet. Gastroenterology & Hepatology. 2017 Jun 1
54 citations
Immunological Balance Is Associated with Clinical Outcome after Autologous Hematopoietic Stem Cell Transplantation in Type 1 Diabetes.
Kelen C. R. Malmegrim, Júlia Teixeira Cottas de Azevedo, Lucas C. M. Arruda, Joana R. F. Abreu, Carlos Eduardo Barra Couri, Gislane Lelis Vilela de Oliveira, Patricia ...> ;Frontiers in Immunology. 2017 Feb 22
1 citations
Stem Cell Transplantation for Refractory Crohn Disease--Reply.
Christopher J Hawkey, James Lindsay, John Gribben> ;JAMA. 2016 Jun 21
Stem Cell Transplantation for Refractory Crohn Disease.
Burt, R. K.,Ruiz, M. A.,Kaiser, R. L.> ;JAMA. 2016 Jun 22
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Journal Articles

Five Year Follow-up After Autologous Peripheral Blood Hematopoietic Stem Cell Transplantation for Refractory, Chronic, Corticosteroid-Dependent Systemic Lupus Erythema...
Allison M Clendenan, Richard K Burt, Michelle A Calvario, Nature

Press Mentions

Christina Applegate Reveals She Has Multiple SclerosisAugust 10th, 2021
Immune System Conditioning Treatment Lessens Attacks in Neuromyelitis OpticaOctober 17th, 2019
Experimental Treatment Showing Promise in Stopping Multiple Sclerosis SymptomsJanuary 16th, 2019
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