RichardAPrestonMD

Nephrology • Miami, FL

Physician

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Office
1400 NW 12th Ave
Miami, FL 33136
Phone+1 305-243-1000

Fax+1 305-243-1538
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Education & Training

University of Miami/Jackson Health SystemFellowship, Nephrology, 1986 - 1988
University of Miami/Jackson Health SystemResidency, Internal Medicine, 1979 - 1982
University of California San Diego School of MedicineClass of 1979

Certifications & Licensure

FL State Medical License 1981 - 2026
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Nephrology

Clinical Trials

Nebivolol Versus Metoprolol: Sodium Sensitivity Start of enrollment: 2010 Dec 01
Completed
Phase 4
Pharmacokinetics of WCK 2349 In Patients With Hepatic Impairment Start of enrollment: 2014 Sep 01
Completed
Phase 1
A Phase 1 Study to Evaluate the Pharmacokinetics of Setmelanotide in Subjects With Varying Degrees of Renal Impairment Start of enrollment: 2020 Jul 09
Completed
Phase 1
Pharmacokinetics of XNW4107 in Subjects With Various Degrees of Renal Function Start of enrollment: 2021 Feb 25
Completed
Phase 1
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Publications & Presentations

PubMed

1 citations
Characterization of Potassium-Induced Natriuresis in Hypertensive Postmenopausal Women During Both Low and High Sodium Intake.
Richard A Preston, David Afshartous, Evelyn V Caizapanta, Rolando Rodco, Eileen Alonso, Alberto B Alonso, Barry J Materson> ;Hypertension. 2022 Apr 1
8 citations
Pharmacokinetics of Gepotidacin in Subjects With Normal Hepatic Function and Hepatic Impairment.
Mohammad Hossain, Courtney Tiffany, Yu Tao, Aline Barth, Thomas Marbury, Richard A. Preston, Etienne Dumont> ;Clinical Pharmacology in Drug Development. 2021 Jun 1
6 citations
Thiazide-Sensitive NCC (Sodium-Chloride Cotransporter) in Human Metabolic Syndrome: Sodium Sensitivity and Potassium-Induced Natriuresis.
Richard A. Preston, David Afshartous, Evelyn V. Caizapanta, Rolando Rodco, Eileen Alonso, Alberto B. Alonso, Barry J. Materson> ;Hypertension. 2021 Jan 4
6 citations
Pharmacokinetics of Voxelotor in Patients With Renal and Hepatic Impairment
Richard A. Preston, Thomas Marbury, Ganesh Balaratnam, Michelle Green, Sandy Dixon, Josh Lehrer-Graiwer, Carla Washington> ;Journal of Clinical Pharmacology. 2021 Apr 1
13 citations
A phase 1, open-label, single-dose study of the pharmacokinetics of zanubrutinib in subjects with varying degrees of hepatic impairment
Ying C. Ou, Richard A. Preston, Thomas Marbury, Zhiyu Tang, William Novotny, Manal Tawashi, Ta Kai Li, Srikumar Sahasranaman> ;Leukemia & Lymphoma. 2020 Feb 7
19 citations
Single-Center Evaluation of the Pharmacokinetics of WCK 5222 (Cefepime-Zidebactam Combination) in Subjects with Renal Impairment.
Richard A. Preston, Grigor Mamikonyan, Stephane DeGraff, Christopher J. Kemper, Allan Xu, Mushtaque Mastim, Ravindra D. Yeole, Rajesh Chavan, Anasuya Patel, H. David F...> ;Antimicrobial Agents and Chemotherapy. 2019 Jan 1
4 citations
Single-Center Investigation of the Pharmacokinetics of WCK 4282 (Cefepime-Tazobactam Combination) in Renal Impairment.
Richard A. Preston, Grigor Mamikonyan, Mushtaque Mastim, Dyal C. Garg, Christopher J. Kemper, Allan Xu, Ravindra D. Yeole, Rajesh Chavan, H. David Friedland, Ashima Bh...> ;Antimicrobial Agents and Chemotherapy. 2019 Sep 23
16 citations
Pharmacokinetics, Safety, and Tolerability of Intravenous Durlobactam and Sulbactam in Subjects with Renal Impairment and Healthy Matched Control Subjects.
John O'Donnell, Richard A. Preston, Grigor Mamikonyan, Emily Stone, Robin Isaacs> ;Antimicrobial Agents and Chemotherapy. 2019 Jul 15
9 citations
Pharmacokinetics and safety of glecaprevir and pibrentasvir in HCV-negative subjects with hepatic impairment
Matthew P. Kosloski, Haoyu Wang, David Pugatch, Federico J. Mensa, E.J. Gane, Eric Lawitz, Thomas Marbury, Richard A. Preston, Jens Kort, Wei Liu> ;European Journal of Clinical Pharmacology. 2019 Feb 6
5 citations
Outcomes of minority patients with very severe hypertension (>220/>120 mmHg).
Richard A. Preston, Rafael Arciniegas, Stephane DeGraff, Jeffrey N. Bernstein, David Afshartous, Barry J. Materson> ;Journal of Hypertension. 2019 Feb 1
16 citations
Severe renal impairment has minimal impact on doravirine pharmacokinetics
Wendy Ankrom, Ka Lai Yee, Rosa I. Sanchez, Adedayo Adedoyin, Li Fan, Thomas Marbury, Richard A. Preston, Marian Iwamoto, Sauzanne Khalilieh> ;Antimicrobial Agents and Chemotherapy. 2018 Jul 27
107 citations
Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.
Shu Yang, Miao Xu, Emily M. Lee, Kirill Gorshkov, Sergey A. Shiryaev, Shihua He, Wei Sun, Yu-Shan Cheng, Xin Hu, Anil Mathew Tharappel, Billy Lu, Antonella Pinto, Chen...> ;Cell Discovery. 2018 Jun 5
4 citations
Pharmacokinetics, Safety, and Tolerability of Single-Dose Elbasvir in Participants with Hepatic Impairment.
William L. Marshall, Hwa Ping Feng, Larissa Wenning, Graigory Garrett, Xiaobi Huang, Fang Liu, Deborah Panebianco, Luzelena Caro, Christine Fandozzi, Kenneth C. Lasset...> ;European Journal of Drug Metabolism and Pharmacokinetics. 2018 Jun 1
11 citations
Effects of Mild to Severe Hepatic Impairment on the Pharmacokinetics of Sonidegib: A Multicenter, Open-Label, Parallel-Group Study
Yves Horsmans, Jocelyn Zhou, Mateva Liudmila, George Golor, Oren Shibolet, Michelle Quinlan, Corinne Emotte, Hildegard Boss, Henry Castro, Dalila Sellami, Richard A. P...> ;Clinical Pharmacokinetics. 2018 Mar 1
1 citations
Single-Center Evaluation of the Pharmacokinetics and Safety of the Angiotensin II Receptor Antagonist Azilsartan Medoxomil in Mild to Moderate Hepatic Impairment.
Caroline Dudkowski, Aziz Karim, Zhen Zhao, Alberto B. Alonso, Dyal C. Garg, Richard A. Preston> ;Journal of Clinical Pharmacology. 2018 Jan 1
16 citations
Effects of Renal Impairment and Hemodialysis on the Pharmacokinetics and Safety of the Glecaprevir and Pibrentasvir Combination in Hepatitis C Virus-Negative Subjects
Matthew P. Kosloski, Weihan Zhao, Thomas Marbury, Richard A. Preston, Michael G. Collins, David Pugatch, Federico J. Mensa, Jens Kort, Wei Liu> ;Antimicrobial Agents and Chemotherapy. 2018 Feb 23
49 citations
Safety, tolerability, and pharmacodynamics of an anti-interleukin-1α/β dual variable domain immunoglobulin in patients with osteoarthritis of the knee: a randomized ph...
S.X. Wang, S.B. Abramson, Mukundan Attur, Morten Karsdal, Richard A. Preston, Carlos J. Lozada, Matthew P. Kosloski, F. Hong, P. Jiang, M.J. Saltarelli, B.A. Hendricks...> ;Osteoarthritis and Cartilage. 2017 Dec 1
6 citations
The Influence of Hepatic and Renal Impairment on the Pharmacokinetics of a Treatment for Herpes Zoster, Amenamevir (ASP2151): Phase 1, Open-Label, Single-Dose, Paralle...
Tomohiro Kusawake, Donna Kowalski, Akitsugu Takada, Kota Kato, Masataka Katashima, James Keirns, Michaelene Lewand, Kenneth C. Lasseter, Thomas Marbury, Richard A. Pre...> ;Advances in Therapy. 2017 Nov 13
16 citations
Prehypertension is real and can be associated with target organ damage.
Manuel Garcia-Estrada, Stephane DeGraff, Richard A. Preston, Barry J. Materson> ;Journal of the American Society of Hypertension. 2017 Nov 1
26 citations
Clinical Pharmacology of Delafloxacin in Patients With Hepatic Impairment
Randall Hoover, Thomas Marbury, Richard A. Preston, Megan Quintas, Laura Lawrence, Susan K. Paulson, David R. Luke, Sue Cammarata> ;Journal of Clinical Pharmacology. 2017 Mar 1
13 citations
Pharmacokinetics and Tolerability of Anti-Hepatitis C Virus Treatment with Ombitasvir, Paritaprevir, Ritonavir, with or Without Dasabuvir, in Subjects with Renal Impai...
Amit Khatri, Sandeep Dutta, Thomas Marbury, Richard A. Preston, Lino Rodrigues, Haoyu Wang, Walid M. Awni, Rajeev M. Menon> ;Clinical Pharmacokinetics. 2017 Feb 1
44 citations
Effect of Renal and Hepatic Impairment on the Pharmacokinetics of Cabozantinib.
Linh Nguyen, Jaymes Holland, David A. Ramies, Richard Mamelok, Natacha Benrimoh, Sabrina Ciric, Thomas Marbury, Richard A. Preston, Douglas M. Heuman, Edith Gavis, Ste...> ;Journal of Clinical Pharmacology. 2016 Sep 1
18 citations
Hypertension in the frail elderly.
Manuel Garcia-Estrada, Richard A. Preston, Barry J. Materson> ;Journal of the American Society of Hypertension. 2016 Jun 1
38 citations
Evidence for a gastrointestinal-renal kaliuretic signaling axis in humans.
Richard A. Preston, David Afshartous, Rolando Rodco, Alberto B. Alonso, Dyal C. Garg> ;Kidney International. 2015 Dec 1
2 citations
The effect of renal and hepatic impairment on the pharmacokinetics of ospemifene, a tissue-selective estrogen agonist/antagonist.
Richard A. Preston, Thomas C. Marbury, Toshihiro Wajima, Shelli Graham> ;American Journal of Therapeutics. 2015 May 1
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