RobertVitoFareseJr.MD

Endocrinology • San Francisco, CA

Diabetes, Lipid Metabolism

Physician

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Office
1001 Potrero Avenue
Bldg 30 Rm 3501k
San Francisco, CA 94110
Phone+1 415-206-4615

Fax+1 415-476-4918
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Summary

Dr. Robert Farese Jr., MD is an endocrinologist in San Francisco, California. He is currently licensed to practice medicine in California, Colorado, and Florida.

Education & Training

University of California (San Francisco)Fellowship, Endocrinology, Diabetes, and Metabolism, 1989 - 1992
University of ColoradoResidency, Internal Medicine, 1985 - 1989
Vanderbilt University School of MedicineClass of 1985

Certifications & Licensure

FL State Medical License 1973 - 2024
CA State Medical License 1989 - 2024
CO State Medical License 1988 - 1989
American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

Elected Member The American Society for Clinical Investigation, 1999

Publications & Presentations

PubMed

7 citations
Conditional targeting of phosphatidylserine decarboxylase to lipid droplets
Santosh Kumar, Chandramohan Chitraju, Robert V. Farese, Tobias C. Walther, Christopher G. Burd> ;Biology Open. 2021 Mar 3
The power of two: lessons from a scientific partnership.
Robert V. Farese, Tobias C. Walther> ;The Journal of Clinical Investigation. 2021 Jan 19
18 citations
A Systematic Protein Turnover Map for Decoding Protein Degradation.
Romain Christiano, Henning Arlt, Sonja Kabatnik, Niklas Mejhert, Zon Weng Lai, Robert V. Farese, Tobias C. Walther> ;Cell Reports. 2020 Nov 10
40 citations
Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.
Chandramohan Chitraju, Alexander W. Fischer, Robert V. Farese, Tobias C. Walther> ;Cell Reports. 2020 Nov 3
26 citations
FIT2 is an acyl–coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis
Michel Becuwe, Laura M. Bond, Antonio Pinto, Sebastian Boland, Niklas Mejhert, Shane D. Elliott, Marcelo Cicconet, Morven Graham, Xinran Liu, Olga Ilkayeva, Alan Sagha...> ;The Journal of Cell Biology. 2020 Oct 5
86 citations
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency
Jiasheng Zhang, Dmitry Velmeshev, Kei Hashimoto, Yu-Hsin Huang, Jeffrey W. Hofmann, Xiaoyu Shi, Jiapei Chen, Andrew M. Leidal, Julian G. Dishart, Michelle K. Cahill, K...> ;Nature. 2020 Aug 31
24 citations
Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting.
Maria-Jesus Olarte, Siyoung Kim, Morris E. Sharp, Jessica M. J. Swanson, Robert V. Farese, Tobias C. Walther> ;Developmental Cell. 2020 Aug 24
3 citations
Atypical PKC: therapeutic target for Alzheimer's?
Robert V. Farese, Mini P. Sajan> ;Aging. 2018 Dec 20
107 citations
Cryo-electron microscopy structure of the lipid droplet-formation protein seipin
Xuewu Sui, Henning Arlt, Kelly P Brock, Zon Weng Lai, Frank DiMaio, Debora S. Marks, Maofu Liao, Robert V. Farese, Tobias C. Walther> ;The Journal of Cell Biology. 2018 Dec 3
11 citations
Progranulin in the hematopoietic compartment protects mice from atherosclerosis
Andrew D. Nguyen, Thi A. Nguyen, Rajesh K. Singh, Delphine Eberlé, Jiasheng Zhang, Jess Porter Abate, Anatalia Robles, Suneil K. Koliwad, Eric J. Huang, Frederick R. M...> ;Atherosclerosis. 2018 Oct 1
24 citations
Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells.
Christina B. K. Jayson, Henning Arlt, Alexander W. Fischer, Zon Weng Lai, Robert V. Farese, Tobias C. Walther> ;Molecular Biology of the Cell. 2018 Aug 15
14 citations
Global Analyses of Selective Insulin Resistance in Hepatocytes Caused by Palmitate Lipotoxicity
Zhihuan Li, Zon Weng Lai, Romain Christiano, Felipe Gazos-Lopes, Tobias C. Walther, Robert V. Farese> ;Molecular & Cellular Proteomics. 2018 Feb 5
45 citations
Taming the sphinx: Mechanisms of cellular sphingolipid homeostasis.
Daniel K. Olson, Florian Fröhlich, Robert V. Farese, Tobias C. Walther> ;Biochimica Et Biophysica Acta. 2016 Aug 1
Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.
Lui H, Zhang J, Makinson SR, Cahill MK, Kelley KW, Huang H, Shang Y, Oldham MC, Martens LH, Gao F, Coppola G, Sloan SA, Hsieh CL, Kim CC, Bigio EH, Weintraub S, Mesula...> ;Cell. 2016-05-05
Targeting Fat: Mechanisms of Protein Localization to Lipid Droplets.
Kory, N.,Farese, R. V.,Walther, T. C.> ;Trends Cell Biol.. 1900 Jan 01
Protein Crowding Is a Determinant of Lipid Droplet Protein Composition.
Kory N, Thiam A, Farese RV, Walther TC> ;Dev. Cell. 2015-08-10
Pharmacological TLR4 Inhibition Protects against Acute and Chronic Fat-Induced Insulin Resistance in Rats.
Zhang N, Liang H, Farese RV, Li J, Musi N, Hussey SE> ;PLoS ONE. 2015-01-01
The Hepatitis C Virus Core Protein Inhibits Adipose Triglyceride Lipase (ATGL)-mediated Lipid Mobilization and Enhances the ATGL Interaction with Comparative Gene Iden...
Camus, G.,Schweiger, M.,Herker, E.,Harris, C.,Kondratowicz, A. S.,Tsou, C. L.,Farese, R. V.,Herath, K.,Previs, S. F.,Roddy, T. P.,Pinto, S.,Zechner, R.,Ott, M.> ;J. Biol. Chem.. 2014 Nov 09
Cardiomyocyte-specific loss of diacylglycerol acyltransferase 1 (DGAT1) reproduces the abnormalities in lipids found in severe heart failure.
Liu L, Trent CM, Fang X, Son N, Jiang H, Blaner WS, Hu Y, Yin Y, Farese RV, Homma S, Turnbull AV, Eriksson JW, Hu S, Ginsberg HN, Huang L, Goldberg IJ> ;J. Biol. Chem.. 2014-10-24
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.
Minami, S. S.,Min, S. W.,Krabbe, G.,Wang, C.,Zhou, Y.,Asgarov, R.,Li, Y.,Martens, L. H.,Elia, L. P.,Ward, M. E.,Mucke, L.,Farese, R. V.,Gan, L.> ;Nat. Med.. 2014 Sep 30
Requirements for pseudosubstrate arginine residues during autoinhibition and phosphatidylinositol 3,4,5-(PO₄)₃-dependent activation of atypical PKC.
Ivey RA, Sajan MP, Farese RV> ;J. Biol. Chem.. 2014-09-05
Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD.
Ward, M. E.,Taubes, A.,Chen, R.,Miller, B. L.,Sephton, C. F.,Gelfand, J. M.,Minami, S.,Boscardin, J.,Martens, L. H.,Seeley, W. W.,Yu, G.,Herz, J.,Filiano, A. J.,Arrant...> ;J. Exp. Med.. 2014 Aug 27
The biophysics and cell biology of lipid droplets.
Thiam, A. R.,Farese, R. V.,Walther, T. C.> ;Nat. Rev. Mol. Cell Biol.. 2013 Nov 14
Progranulin: at the interface of neurodegenerative and metabolic diseases.
Nguyen, A. D.,Nguyen, T. A.,Martens, L. H.,Mitic, L. L.,Farese, R. V.> ;Trends Endocrinol. Metab.. 2013 Sep 10
Cellular Fatty Acid metabolism and cancer.
Currie, E.,Schulze, A.,Zechner, R.,Walther, T. C.,Farese, R. V.> ;Cell Metab.. 2013 Aug 6
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