RobertJJohnstonMD

PubMed

• 57 citations
  IL15 Stimulation with TIGIT Blockade Reverses CD155-mediated NK-Cell Dysfunction in Melanoma
  Joe-Marc Chauvin, Mignane B. Ka, Ornella Pagliano, Carmine Menna, Quanquan Ding, Richelle DeBlasio, Cindy Sanders, Jiajie Hou, Xian-Yang Li, Soldano Ferrone, Diwakar D...> ;Clinical Cancer Research. 2020 Oct 15
• 37 citations
  CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8+ T Cells.
  Matthias Braun, Amelia Roman Aguilera, Ashmitha Sundarrajan, Dillon Corvino, Kimberley Stannard, Sophie Krumeich, Indrajit Das, Luize G. Lima, Lizeth G. Meza Guzman, K...> ;Immunity. 2020 Oct 13
• 38 citations
  A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target
  Zachary T. Freeman, Thomas R. Nirschl, Daniel H. Hovelson, Robert J. Johnston, John J. Engelhardt, Mark J. Selby, Christina M. Kochel, Ruth Y. Lan, Jingyi Zhai, Ali Gh...> ;The Journal of Clinical Investigation. 2020 Jun 24
• 137 citations
  VISTA is an acidic pH-selective ligand for PSGL-1
  Robert J. Johnston, Linhui Julie Su, Jason Pinckney, David A Critton, Eric Boyer, Arathi Krishnakumar, Martin J. Corbett, Andrew Rankin, Dibella Rose A, Lynne Campbell...> ;Nature. 2019 Oct 1
• 51 citations
  CD96 Is an Immune Checkpoint That Regulates CD8+ T-cell Antitumor Function
  Deepak Mittal, Ailin Lepletier, Jason Madore, Amelia Roman Aguilera, Kimberley Stannard, Stephen J. Blake, Vicki L. J. Whitehall, Cheng Liu, Mark Bettington, Kazuyoshi...> ;Cancer Immunology Research. 2019 Mar 20
• 2 citations
  A Fourteen-Year Experience with Vascular Anomalies Encountered during Transaxillary Rib Resection for Thoracic Outlet Syndrome.
  Jeniann A. Yi, Robert J. Johnston, Mark R. Nehler, Douglas R. Gibula, Kristen Alix, Natalia O. Glebova, Charles O. Brantigan> ;Annals of Vascular Surgery. 2017 Apr 1
• 20 citations
  Bcl6 middle domain repressor function is required for T follicular helper cell differentiation and utilizes the corepressor MTA3
  J. Philip Nance, Simon Bélanger, Robert J. Johnston, Joyce K. Hu, Toshitada Takemori, Shane Crotty> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 Oct 27
• 22 citations
  Cutting Edge: T Follicular Helper Cell Differentiation Is Defective in the Absence of Bcl6 BTB Repressor Domain Function
  J. Philip Nance, Simon Bélanger, Robert J. Johnston, Toshitada Takemori, Shane Crotty> ;Journal of Immunology. 2015 Jun 15
• 31 citations
  The checkpoint inhibitor TIGIT limits antitumor and antiviral CD8+ T cell responses
  Robert J. Johnston, Xin Yu, Jane L. Grogan> ;OncoImmunology. 2015 May 27
• 637 citations
  The Immunoreceptor TIGIT Regulates Antitumor and Antiviral CD8+ T Cell Effector Function
  Robert J. Johnston, Laetitia Comps-Agrar, Jason A. Hackney, Xin Yu, Mahrukh Huseni, Yagai Yang, Summer Park, Vincent Javinal, Henry Chiu, Bryan Irving, Dan L. Eaton, J...> ;Cancer Cell. 2014 Dec 8
• 77 citations
  In vivo RNA interference screens identify regulators of antiviral CD4+ and CD8+ T cell differentiation
  Runqiang Chen, Simon Bélanger, Megan A. Frederick, Bin Li, Robert J. Johnston, Nengming Xiao, Yun-Cai Liu, Sonia Sharma, Bjoern Peters, Anjana Rao, Shane Crotty, Matth...> ;Immunity. 2014 Aug 21
• 26 citations
  EBI2 Is a Negative Regulator of Type I Interferons in Plasmacytoid and Myeloid Dendritic Cells
  Eugene Y. Chiang, Robert J. Johnston, Jane L. Grogan> ;PLOS ONE. 2013 Dec 26
• 173 citations
  Bcl6 Expressing Follicular Helper CD4 T Cells Are Fate Committed Early and Have the Capacity To Form Memory
  Youn Soo Choi, Jessica A. Yang, Isharat Yusuf, Robert J. Johnston, Jason A. Greenbaum, Bjoern Peters, Shane Crotty> ;Journal of Immunology. 2013 Apr 15
• 362 citations
  STAT5 is a potent negative regulator of TFH cell differentiation
  Robert J. Johnston, Youn Soo Choi, Jeffrey A. Diamond, Jessica A. Yang, Shane Crotty> ;Journal of Experimental Medicine. 2012 Feb 13
• Stochastic De-repression of Rhodopsins in Single Photoreceptors of the Fly Retina.
  Sood, P., Johnston, R.J., Kussell, E.> ;PLoS Comput Biol. 2012 Feb
• Interlocked feedforward loops control cell-type-specific rhodopsin expression in the Drosophila eye.
  Johnston, R.J., Otake, Y., Sood, P., Vogt, N., Behnia, R., Vasiliauskas, D., McDonald, E., Xie, B., Koenig, S., Wolf, R., Cook, T., Gebelein, B., Kussell, E., Nakagosh...> ;Cell. 2011 Jun 10
• 673 citations
  ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6.
  Youn Soo Choi, Robin Kageyama, Danelle Eto, Tania C. Escobar, Robert J. Johnston, Laurel A. Monticelli, Christopher Lao, Shane Crotty> ;Immunity. 2011 Jun 24
• Stochastic mechanisms of cell fate specification that yield random or robust outcomes.
  Johnston, R.J., Desplan, C.> ;Annu Rev Cell Dev Biol. 2010
• 308 citations
  Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150).
  Isharat Yusuf, Robin Kageyama, Laurel A. Monticelli, Robert J. Johnston, Daniel DiToro, Kyle Hansen, Burton E. Barnett, Shane Crotty> ;Journal of Immunology. 2010 Jul 1
• Preview. A penetrating look at stochasticity in development.
  Johnston, R.J., Desplan, C.> ;Cell. 2010 Mar 5
• 376 citations
  Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation
  Shane Crotty, Robert J. Johnston, Stephen P. Schoenberger> ;Nature Immunology. 2010 Feb 1
• 1121 citations
  Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation.
  Robert J. Johnston, Amanda C. Poholek, Daniel DiToro, Isharat Yusuf, Danelle Eto, Burton E. Barnett, Alexander L. Dent, Joe Craft, Shane Crotty> ;Science. 2009 Aug 21
• Normal ovarian function and assessment of ovarian reserve in the survivor of childhood cancer.
  Johnston, R.J., Wallace, W.B.> ;Pediatr Blood Cancer. 2009-08-01
• 140 citations
  Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities.
  Alessandro Sette, Magdalini Moutaftsi, Juan Moyron-Quiroz, Megan McCausland, D. Huw Davies, Robert J. Johnston, Bjoern Peters, Mohammed Rafii-El-Idrissi Benhnia, Julia...> ;Immunity. 2008 Jun 13
• Iroquois complex genes induce co-expression of rhodopsins in Drosophila.
  Mazzoni, E.O., Celik, A., Wernet, M.F., Vasiliauskas, D., Johnston, R.J., Cook, T.A., Pichaud, F., Desplan, C.> ;PLoS Biol. 2008 Apr 22
• Join now to see all