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Office
300 Longwood Ave
Boston, MA 02115Phone+1 617-632-3951- Is this information wrong?
Education & Training
- Children's Hospital/Boston Medical CenterResidency, Pediatrics, 1996 - 1998
- University of Texas Southwestern Medical SchoolClass of 1996
Certifications & Licensure
- MA State Medical License 1998 - 2024
- NY State Medical License 2014 - 2016
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2010
Publications & Presentations
PubMed
- PI3Kγ maintains the self-renewal of acute myeloid leukemia stem cells by regulating the pentose phosphate pathway.Hao Gu, Chiqi Chen, Zhi-Shuai Hou, Xia-Di He, Shaozhen Xie, Jing Ni, Changli Qian, Xin Cheng Dr, Tao Jiang Dr, Ce Yang, Thomas M Roberts Dr, Junke Zheng, Judith A Varn...> ;Blood. 2024 Jan 25
- Inherited blood cancer predisposition through altered transcription elongation.Zhao, J., Cato, L., Arora, U., Bao, E., Bryant, S., Williams, N., Jia, Y., Goldman, S., Nangalia, J., Erb, M., Vos, S., Armstrong, S., Sankaran, V.> ;Cell. 2024 Feb 1
- Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia.Tubío-Santamaría, N., Jayavelu, A., Schnoeder, T., Eifert, T., Hsu, C., Perner, F., Zhang, Q., Wenge, D., Hansen, F., Kirkpatrick, J., Jyotsana, N., Lane, S., von Eyss...> ;Molecular Cancer. 2023 Dec 4
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Journal Articles
- Article HOXA9 Reprograms the Enhancer Landscape to Promote LeukemogenesisRoss L Levine, Jay L Hess, Sheng Cai, Scott A Armstrong, ScienceDirect
Abstracts/Posters
- A Phase Ib/II Study of the Histone Methyltransferase Inhibitor Pinometostat in Combination with Azacitidine in Patients with 11q23-Rearranged Acute Myeloid LeukemiaScott A. Armstrong, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
- Tudor Domain-Focused CRISPR Dropout Screen Identifies SGF29 As a Novel Essential Gene in MLL-Rearranged LeukemiasScott A. Armstrong, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- Leukemia Cell of Origin Influences p53 Activity and Therapeutic Sensitivity Via an Evi1-Dependent MechanismScott A. Armstrong, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Lectures
- Biochemical and Genetic Insights Into MLL/11q23 Translocation Leukemia60th American Society of Hematology Annual Meeting - 12/2/2018
- High-Density CRISPR Scan Identifies Functional Regions of DOT1L That Mediate Therapeutic Response in MLL-r Leukemia2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Press Mentions
- Experimental Pill Sends a Third of Leukemia Patients into Complete Remission in an Early TrialMarch 24th, 2023
- Experimental Pill Sends a THIRD of Patients with Leukemia into Complete Remission in Early TrialMarch 24th, 2023
- Stop & Shop Kicks off Annual ‘Help Cure Childhood Cancer’ CampaignMarch 3rd, 2023
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Grant Support
- Molecular Pathogenesis Of MLL-AF4 LeukemiasNational Cancer Institute2010–2012
- MLL Fusion Genes In Myeloid And Lymphoid LeukemiasNational Cancer Institute2008–2012
- Comprehensive Phenotypic Comparison Of Normal And Cancer Stem CellsNational Cancer Institute2009–2010
- The Core Apoptotic Pathway Controlling Glucocorticoid-Induced Apoptosis In AllNational Cancer Institute2006–2010
- MLL Gene Regulation In Hematopoiesis And LeukemiaNational Cancer Institute2005–2006
- MLL Gene Regulation In Hematopoiesis And LeukemiaNational Cancer Institute2001–2004
Hospital Affiliations
- Dana-Farber Cancer InstituteBoston, Massachusetts
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