SethLedermanMD

Rheumatology • New York, NY

Physician

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Office
166 E 96th St
Apt 17a
New York, NY 10128
Phone+1 212-644-2610

Fax+1 212-923-5700
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Summary

Dr. Seth Lederman, MD is a rheumatologist in New York, New York. He is currently licensed to practice medicine in New York.

Education & Training

Columbia University Vagelos College of Physicians and SurgeonsClass of 1983

Certifications & Licensure

NY State Medical License 1985 - 2026

Publications & Presentations

PubMed

3 citations
Predictors of Response to Prolonged Exposure, Sertraline, and Their Combination for the Treatment of Military PTSD.
Sheila A.M. Rauch, H. Myra Kim, Seth Lederman, Gregory M. Sullivan, Ron Acierno, Peter W. Tuerk, Naomi M. Simon, Margaret R. Venners, Sonya B. Norman, Carolyn B. Allar...> ;The Journal of Clinical Psychiatry. 2021 Jun 15
5 citations
Randomized clinical trial of bedtime sublingual cyclobenzaprine (TNX-102 SL) in military-related PTSD and the role of sleep quality in treatment response.
Gregory M. Sullivan, R. Michael Gendreau, Judith Gendreau, Perry Scott Peters, Ashild Peters, Jean Engels, Bruce L. Daugherty, Benjamin Vaughn, Frank W. Weathers, Seth...> ;Psychiatry Research. 2021 Apr 30
123 citations
Construction of an infectious horsepox virus vaccine from chemically synthesized DNA fragments
Ryan S. Noyce, Seth Lederman, David H. Evans> ;Plos One. 2018 Jan 19
39 citations
Effects of bedtime very low dose cyclobenzaprine on symptoms and sleep physiology in patients with fibromyalgia syndrome: a double-blind randomized placebo-controlled ...
Moldofsky H, Harris Hw, Archambault Wt, Kwong T, Seth Lederman> ;The Journal of Rheumatology. 2011 Dec 1
74 citations
CD20-induced B cell death can bypass mitochondria and caspase activation.
L. E. Van Der Kolk, L. M. Evers, C Omene, Susanne M.A. Lens, Seth Lederman, R. A. W. Van Lier, M. H. J. Van Oers, Eric Eldering> ;Leukemia. 2002 Sep 1
627 citations
Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4.
Chih-Chao Chang, Rodica Ciubotariu, John S. Manavalan, J. Yuan, Adriana I. Colovai, Flavia Piazza, Seth Lederman, Marco Colonna, Raffaello Cortesini, Riccardo Dalla-Fa...> ;Nature Immunology. 2002 Mar 1
9 citations
Expression and function of TRAF-3 splice-variant isoforms in human lymphoma cell lines
Christopher Gamper, Coral O Omene, Winfried Van Eyndhoven, Grace D Glassman, Seth Lederman> ;Human Immunology. 2001 Oct 1
4 citations
The role of CD154 (CD40-ligand) in costimulation.
Seth Lederman> ;Transplantation Proceedings. 2001 Feb 1
69 citations
Induction of xenoreactive CD4+ T-cell anergy by suppressor CD8+CD28- T cells.
Adriana I. Colovai, Zhuoru Liu, Rodica Ciubotariu, Seth Lederman, Raffaello Cortesini, Nicole Suciu-Foca> ;Transplantation. 2000 Apr 1
21 citations
TRAF-3 interacts with p62 nucleoporin, a component of the nuclear pore central plug that binds classical NLS-containing import complexes
C.J Gamper, W.G van Eyndhoven, E Schweiger, M Mossbacher, B Koo, Seth Lederman> ;Molecular Immunology. 2000 Jan 1
113 citations
T suppressor lymphocytes inhibit NF-kappa B-mediated transcription of CD86 gene in APC.
Jianfeng Li, Zhuoru Liu, Shuiping Jiang, Raffaello Cortesini, Seth Lederman, Nicole Suciu-Foca> ;Journal of Immunology. 1999 Dec 15
68 citations
Inhibition of CD40 signaling pathway in antigen presenting cells by T suppressor cells
Zhuoru Liu, Sorina Tugulea, Raffaello Cortesini, Seth Lederman, Nicole Suciu-Foca> ;Human Immunology. 1999 Jul 1
30 citations
TRAF-3 mRNA splice-deletion variants encode isoforms that induce NF-κB activation
W.G van Eyndhoven, C.J Gamper, E. Cho, W.J.M. Mackus, Seth Lederman> ;Molecular Immunology. 1999 Jul 1
11 citations
Antigen presenting cells integrate opposing signals from CD4+ and CD8+ regulatory T lymphocytes to arbitrate the outcomes of immune responses.
Seth Lederman, Nicole Suciu-Foca> ;Human Immunology. 1999 Jul 1
11 citations
An aggressive form of polyarticular arthritis in a man with CD154 mutation (X-linked hyper-IgM syndrome).
Elizabeth A. Webster, Aarif Y. Khakoo, Wendeline J. M. Mackus, Michael Karpusas, David W. Thomas, Anne Davidson, Charles L. Christian, Seth Lederman> ;Arthritis and Rheumatism. 1999 Jun 1
14 citations
A single gene for human TRAF-3 at chromosome 14q32.3 encodes a variety of mRNA species by alternative polyadenylation, mRNA splicing and transcription initiation.
W.G van Eyndhoven, Dale Frank, Sergey Kalachikov, Aileen M. Cleary, David I. Hong, E. Cho, S. Nasr, A.J. Perez, W.J.M. Mackus, Eftihia Cayanis, S. Wellington, Stuart G...> ;Molecular Immunology. 1998 Dec 15
79 citations
Induction of MHC-class I restricted human suppressor T cells by peptide priming in vitro.
Shuiping Jiang, Sorina Tugulea, Giuseppina Pennesi, Zhuoru Liu, Arend Mulder, Seth Lederman, Paul L. Harris, Raffaello Cortesini, Nicole Suciu-Foca> ;Human Immunology. 1998 Nov 1
56 citations
Fas ligand is constitutively secreted by prostate cancer cells in vitro.
Qiang Yuan Liu, Mark A. Rubin, Coral O Omene, Seth Lederman, Cy A. Stein> ;Clinical Cancer Research. 1998 Jul 1
13 citations
Intracerebroventricular Injection of Interleukin-1 Suppresses Peripheral Lymphocyte Function in the Primate
Gregory M. Sullivan, S. M. Canfield, Seth Lederman, Ennian Xiao, Michel Ferin, Sharon L. Wardlaw> ;Neuroimmunomodulation. 1997 Jan 1
11 citations
Polydeoxyguanine Motifs in a 12-mer Phosphorothioate Oligodeoxynucleotide Augment Binding to the v3 Loop of HIV-1 gpl20 and Potency of HIV-1 Inhibition Independently o...
Seth Lederman, Gregory M. Sullivan, Lyuba Benimetskaya, Israel Lowy, Kevin Land, Zahangir Khaled, Aileen M. Cleary, Leonid Yakubov, C. A. Stein> ;Antisense & Nucleic Acid Drug Development. 1996 Jan 1
25 citations
The central role of the CD40-ligand and CD40 pathway in T-lymphocyte-mediated differentiation of B lymphocytes.
Seth Lederman, Aileen M. Cleary, Michael J. Yellin, Dale Frank, Michael Karpusas, David W. Thomas, Leonard Chess> ;Current Opinion in Hematology. 1996 Jan 1
64 citations
Opposing roles of CD95 (Fas/APO-1) and CD40 in the death and rescue of human low density tonsillar B cells.
Aileen M. Cleary, Sarah M. Fortune, M J Yellin, Leonard Chess, Seth Lederman> ;Journal of Immunology. 1995 Oct 1
192 citations
Ligation of CD40 on fibroblasts induces CD54 (ICAM-1) and CD106 (VCAM-1) up-regulation and IL-6 production and proliferation.
Michael J. Yellin, Stephen Winikoff, Sarah M. Fortune, David Baum, Mary K. Crow, Seth Lederman, Leonard Chess> ;Journal of Leukocyte Biology. 1995 Aug 1
400 citations
Involvement of CRAF1, a relative of TRAF, in CD40 signaling
Genhong Cheng, Aileen M. Cleary, Zheng-Sheng Ye, David I. Hong, Seth Lederman, David Baltimore> ;Science. 1995 Mar 10
61 citations
CD40 ligand (CD40L) expression and B cell function in agammaglobulinemia with normal or elevated levels of IgM (HIM). Comparison of X-linked, autosomal recessive, and ...
Robin E. Callard, Susan H. Smith, J. Herbert, Gareth Morgan, Munoree Padayachee, Seth Lederman, Leonard Chess, R. A. Kroczek, William C. Fanslow, R. J. Armitage> ;Journal of Immunology. 1994 Oct 1
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Press Mentions

Tonix Pharmaceuticals Announces the Isolation and Characterization of the (S)-Isomer of Tianeptine, TNX-4300 (Estianeptine), Now Under Development for Psychiatric and Neurodegenerative DiseasesMay 23rd, 2023
A New Depression Drug Being Developed by Tonix May Side-Step Treatment-Limiting Effects of Nearly All Current Antidepressants in the USApril 27th, 2023
Tonix Pharmaceuticals Announces Two Publications of Data in American Journal of Transplantation Showing TNX-1500 (Anti-CD40L mAb) Prolongs Nonhuman Primate Renal and Heart Allograft SurvivalApril 17th, 2023
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