ShaneAdamShapiroMD

Family Medicine • Jacksonville, FL

Sports Medicine (Non-Surgical)

Associate Professor, Orthopedics, Mayo Clinic College of Medicine and Science

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Office
4500 San Pablo Rd S
Jacksonville, FL 32224
Phone+1 904-953-2000
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Education & Training

Mayo Clinic College of Medicine and Science (Jacksonville)Fellowship, Sports Medicine (Family Medicine), 2004 - 2005
Mayo Clinic College of Medicine and Science (Jacksonville)Residency, Family Medicine, 2001 - 2004
University of Virginia School of MedicineClass of 2001

Certifications & Licensure

FL State Medical License 2002 - 2025
American Board of Family Medicine Family Medicine
American Board of Family Medicine Sports Medicine

Clinical Trials

Use of Autologous Bone Marrow Aspirate Concentrate in Painful Knee Osteoarthritis Start of enrollment: 2013 Aug 01
Completed
Phase 1
Conventional Platelet-Rich Plasma Versus Concentrated Bone Marrow Stem Cell Injections for Osteoarthritis of the Knee Start of enrollment: 2019 Sep 01
Withdrawn
Phase 2
Intra-articular Transplantation of Autologous Adipose Derived Stromal Vascular Faction (SVF) for Treatment of Osteoarthritis of the Knee Start of enrollment: 2019 Jul 02
Recruiting
Phase 1

Publications & Presentations

PubMed

2 citations
Author Correction: Patients seeking stem cell therapies-a prospective qualitative analysis from a Regenerative Medicine Consult Service.
Jennifer R Arthurs, Lisa M Nordan, Brian H Hultgren, Michael G Heckman, Dayana Martinez, Zubin Master, Shane A Shapiro> ;NPJ Regenerative Medicine. 2023 Feb 2
2 citations
Tiered approach to considering orthobiologics for patients with musculoskeletal conditions.
Shane A Shapiro, Zubin Master, Jennifer R Arthurs, Kenneth Mautner> ;British Journal of Sports Medicine. 2023 Feb 1
3 citations
Patients seeking stem cell therapies-a prospective qualitative analysis from a Regenerative Medicine Consult Service.
Jennifer R Arthurs, Lisa M Nordan, Brian H Hultgren, Michael G Heckman, Dayana Martinez, Zubin Master, Shane A Shapiro> ;NPJ Regenerative Medicine. 2022 Mar 25
8 citations
American Medical Society for Sports Medicine Position Statement: Principles for the Responsible Use of Regenerative Medicine in Sports Medicine.
Jonathan T. Finnoff, Tariq M Awan, Joanne Borg-Stein, Kimberly G. Harmon, Daniel C. Herman, Gerard A. Malanga, Zubin Master, Kenneth Mautner, Shane A. Shapiro> ;Clinical Journal of Sport Medicine. 2021 Nov 1
5 citations
Highlights from the American Medical Society for Sports Medicine position statement on responsible use of regenerative medicine and orthobiologics in sports medicine.
Shane A. Shapiro, Jonathan T. Finnoff, Tariq M Awan, Joanne Borg-Stein, Kimberly G. Harmon, Daniel C. Herman, Gerard A. Malanga, Zubin Master, Kenneth Mautner> ;British Journal of Sports Medicine. 2021 Oct 31
5 citations
Academic Physician Specialists' Approaches to Counseling Patients Interested in Unproven Stem Cell and Regenerative Therapies-A Qualitative Analysis.
Cambray Smith, Aidan P. Crowley, Megan Munsie, Atta Behfar, Erin S. DeMartino, Nathan P. Staff, Shane A. Shapiro, Zubin Master> ;Mayo Clinic Proceedings. 2021 Aug 25
1 citations
Use of Bone Marrow Concentrate to Treat Pain and Musculoskeletal Disorders: An Academic Delphi Investigation.
Christopher J. Centeno, Mairin A Jerome, Sarah M. Pastoriza, Shane A. Shapiro, Ken Mautner, Gerard A. Malanga, Michael J. DePalma, R Amadeus Mason, Ian Stemper, Ehren ...> ;Pain Physician. 2021 May 1
10 citations
Complications Following Biologic Therapeutic Injections: A Multicenter Case Series
Claire D. Eliasberg, Daniel A. Nemirov, Bert R. Mandelbaum, Andrew D. Pearle, John M. Tokish, Michael R. Baria, Peter J. Millett, Shane A. Shapiro, Scott A. Rodeo> ;Arthroscopy. 2021 Aug 1
7 citations
Academic physician specialists’ views toward the unproven stem cell intervention industry: areas of common ground and divergence
Cambray Smith, Aidan Crowley, Megan Munsie, Erin S. DeMartino, Nathan P. Staff, Shane A. Shapiro, Zubin Master> ;Cytotherapy. 2021 Apr 1
5 citations
Oil injection for cosmetic enhancement of the upper extremities: a case report and review of literature.
Andrea Sisti, Maria T Huayllani, David J. Restrepo, Daniel Boczar, Oscar J. Manrique, Peter Niclas Broer, Shane A. Shapiro, Antonio J. Forte> ;Acta Bio-Medica. 2020 Sep 7
19 citations
A Randomized, Controlled Pilot Trial Comparing Platelet-Rich Plasma to Topical Minoxidil Foam for Treatment of Androgenic Alopecia in Women
Alison J. Bruce, Thais P. Pincelli, Michael G. Heckman, Cheryl M. Desmond, Jennifer R. Arthurs, Nancy N. Diehl, Erika J. Douglass, Charles J. Bruce, Shane A. Shapiro> ;Dermatologic Surgery. 2020 Jun 1
1 citations
A three-dimensional computed tomography study to determine the ideal method for fluoroscopically-guided bone marrow aspiration from the iliac crest.
Ryan S D'Souza, Langping Li, Shuai Leng, Christine L. Hunt, Luke Law, Casey Muir, Jason S. Eldrige, Mohamad Bydon, Meng Chi, Shane A. Shapiro, William D. Mauck, Wenchu...> ;Bosnian Journal of Basic Medical Sciences. 2020 May 11
15 citations
Challenging misinformation and engaging patients: characterizing a regenerative medicine consult service.
Cambray Smith, Charlene Martin-Lillie, Jennifer Dens Higano, Leigh Turner, Sydney Phu, Jennifer R. Arthurs, Timothy J. Nelson, Shane A. Shapiro, Zubin Master> ;Regenerative Medicine. 2020 Mar 1
44 citations
Adipose-Derived Biogenic Nanoparticles for Suppression of Inflammation
Ming Tian, Taylor Ticer, Qikun Wang, Sierra A. Walker, Anthony Pham, Annie Suh, Sara Busatto, Irina Davidovich, Rawan Al-kharboosh, Laura J. Lewis-Tuffin, Baoan Ji, Al...> ;Small. 2020 Mar 1
27 citations
Bone Marrow Concentrate (BMC) Therapy in Musculoskeletal Disorders: Evidence-Based Policy Position Statement of American Society of Interventional Pain Physicians (ASI...
Laxmaiah Manchikanti, Christopher J. Centeno, Sairam Atluri, Sheri L. Albers, Shane A. Shapiro, Gerard A. Malanga, Alaa Abd-Elsayed, Mairin A Jerome, Joshua A Hirsch, ...> ;Pain Physician. 2020 Mar 1
12 citations
Glenohumeral Osteoarthritis: The Role for Orthobiologic Therapies Platelet-Rich Plasma and Cell Therapies
Luciano A. Rossi, Nicolas S. Piuzzi, Shane A. Shapiro> ;JBJS Reviews. 2020 Feb 1
6 citations
Cash-Based Stem-Cell Clinics: The Modern Day Snake Oil Salesman? A Report of Two Cases of Patients Harmed by Intra-articular Stem Cell Injections.
John Taliaferro, Shane A. Shapiro, Daniel P. Montero, Glenn G. Shi, Benjamin K. Wilke> ;JBJS Case Connector. 2019 Dec 1
41 citations
Quantitative T2 MRI Mapping and 12-Month Follow-up in a Randomized, Blinded, Placebo Controlled Trial of Bone Marrow Aspiration and Concentration for Osteoarthritis of...
Shane A. Shapiro, Jennifer R. Arthurs, Michael G. Heckman, Joseph M. Bestic, Shari E. Kazmerchak, Nancy N. Diehl, Abba C. Zubair, Mary I. O'Connor> ;Cartilage. 2019 Oct 1
60 citations
Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation.
Annie Suh, Anthony Pham, Mikel Jean Cress, Thais P. Pincelli, Sarvam P. TerKonda, Alison J. Bruce, Abba C. Zubair, Joy Wolfram, Shane A. Shapiro> ;Ageing Research Reviews. 2019 Sep 1
49 citations
Organotropic drug delivery: Synthetic nanoparticles and extracellular vesicles.
Sara Busatto, Anthony Pham, Annie Suh, Shane A. Shapiro, Joy Wolfram> ;Biomedical Microdevices. 2019 Apr 15
13 citations
Preparing regenerative therapies for clinical application: proposals for responsible translation.
Shane A. Shapiro, Cambray Smith, Jennifer R. Arthurs, Zubin Master> ;Regenerative Medicine. 2019 Jan 17
218 citations
Tangential Flow Filtration for Highly Efficient Concentration of Extracellular Vesicles from Large Volumes of Fluid
Sara Busatto, George K. Vilanilam, Taylor Ticer, Wen-Lang Lin, Dennis W. Dickson, Shane A. Shapiro, Paolo Bergese, Joy Wolfram> ;Cells. 2018 Dec 16
Regenerative Medicine in the State of Florida: Letter Outlining the Florida Organization for Regenerative Medicine.
Charles J. Bruce, Guojun Bu, John M. Centanni, Mary D. Davis, Jon Dobson, Joshua M. Hare, Gregg B. Fields, Richard Jove, Norma S. Kenyon, Aisha Khan, Keith L. March, S...> ;Stem Cells Translational Medicine. 2018 Jul 1
2 citations
Micro-fragmented adipose tissue for treatment of knee osteoarthritis with Baker's cyst: A case study
Jennifer R. Arthurs, Cheryl M. Desmond, Sarvam P. TerKonda, Shane A. Shapiro> ;BMJ Case Reports. 2018 Jun 4
4 citations
Bone marrow aspiration for regenerative orthopedic intervention: technique with ultrasound guidance for needle placement.
Shane A. Shapiro, Jennifer R. Arthurs> ;Regenerative Medicine. 2017 Sep 11
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Press Mentions

Science Saturday: Orthobiologics Can Be Nature’s Healing AgentsMay 20th, 2023
How Stem Cell Therapy Is Saving LivesFebruary 6th, 2023
Real-World Evidence Study of Regenerative Medicine and Shoulder SurgeryNovember 17th, 2022
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