SherifShafikFaragMD

Hematology • Indianapolis, IN

Professor, Medicine, Indiana University School of Medicine

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Office
980 West Walnut Street
R3 Walther Hall, C414
Indianapolis, IN 46202
Phone+1 317-274-0843

Fax+1 317-274-5645
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Summary

Faculty Profile

IU School of Medicine is the largest medical school in the US and is annually ranked among the top medical schools in the nation by US News & World Report. The

Education & Training

University of MelbournePhD, Medicine, 1991 - 1995
University of Melbourne Faculty of MedicineClass of 1984, MB BS

Certifications & Licensure

IN State Medical License 2006 - 2025
OH State Medical License 1999 - 2025
MI State Medical License 2021 - 2024
American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2009-2014
America's Top Doctors for Cancer Castle Connolly, 2008-2013
Indianapolis Monthly Castle Connolly, 2009-2011, 2013

Clinical Trials

Pentostatin in Treating Patients With Refractory Chronic Graft-Versus-Host Disease Start of enrollment: 2003 Dec 01
Completed
Phase 2
Alemtuzumab Plus Fludarabine and Melphalan With or Without Cyclosporine, Mycophenolate Mofetil, and Low-Dose Total-Body Irradiation Therapy Followed by Donor Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer Start of enrollment: 2006 May 01
Withdrawn
Phase 1, Phase 2
An Open-label, Dose-escalation Safety and Tolerability Trial Assessing Anti-KIR (1-7F9) in Subjects With Multiple Myeloma Start of enrollment: 2007 May 01
Completed
Phase 1
A Phase I Trial of Alloreactive Cell Infusion Following Transplantation of Haplotype Cells in Patients With Myeloid Malignancies Start of enrollment: 2007 Aug 01
Terminated
Phase 1
Phase 2 Haplotype Mismatched HSCT in Patients With Hematological Malignancies Start of enrollment: 2007 Aug 07
Terminated
Phase 2
Sitagliptin Umbilical Cord Blood Transplant Study Start of enrollment: 2009 Mar 01
Completed
Phase 2
Relationship Between Natural Killer Cells' Ability to Kill Leukemia Cells and the Outcome of Patients With Acute Myeloid Leukemia Previously Treated With Interleukin-2 Start of enrollment: 2004 Jan 01
Completed
Selecting a Favorable KIR Donor in Unrelated HCT for AML Start of enrollment: 2011 Jun 01
Completed
Not Applicable
Allo Transplant Followed by Lenalidomide and Sirolimus Maintenance in High-Risk Multiple Myeloma (MM) Start of enrollment: 2011 Feb 07
Terminated
Phase 1, Phase 2
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) Start of enrollment: 2011 Oct 01
Recruiting
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

2 citations
A phase 2 trial of CD24Fc for prevention of graft-versus-host disease.
John Magenau, Samantha Jaglowski, Joseph Uberti, Sherif S Farag, Mary Mansour Riwes, Attaphol Pawarode, Sarah Anand, Monalisa Ghosh, John Maciejewski, Thomas Braun, Ma...> ;Blood. 2024 Jan 4
3 citations
NCCN Guidelines® Insights: Hematopoietic Cell Transplantation, Version 3.2022.
Ayman Saad, Alison Loren, Javier Bolaños-Meade, George Chen, Daniel Couriel, Antonio Di Stasi, Areej El-Jawahri, Hany Elmariah, Sherif Farag, Krishna Gundabolu, Jonath...> ;Journal of the National Comprehensive Cancer Network. 2023 Feb 1
Efficacy, safety, and cost of mobilization strategies in multiple myeloma: a prospective, observational study.
Binod Dhakal, Mei-Jei Zhang, Linda J Burns, Xiaoying Tang, Christa Meyer, Lih-Wen Mau, Ajay K Nooka, Edward Stadtmauer, Ivana N Micallef, Joseph McGuirk, Luciano Costa...> ;Haematologica. 2023 Aug 1
The impacts of total body irradiation on umbilical cord blood hematopoietic stem cell transplantation.
Hao Wang, Kristin N Berger, Elizabeth L Miller, Wei Fu, Larisa Broglie, Frederick D Goldman, Heiko Konig, Su Jin Lim, Arthur S Berg, Julie-An Talano, Melanie A Comito,...> ;Therapeutic Advances in Hematology. 2023 Jan 1
16 citations
Age is no barrier for adults undergoing HCT for AML in CR1: contemporary CIBMTR analysis.
Joseph E Maakaron, Mei-Jie Zhang, Karen Chen, Sunil Abhyankar, Vijaya Raj Bhatt, Saurabh Chhabra, Najla El Jurdi, Sherif S Farag, Fiona He, Mark Juckett, Marcos de Lim...> ;Bone Marrow Transplantation. 2022 Jun 1
3 citations
A biomarker panel for risk of early respiratory failure following hematopoietic cell transplantation.
Courtney M Rowan, Lincoln Smith, Matthew P Sharron, Laura Loftis, Sapna Kudchadkar, Christine N Duncan, Francis Pike, Paul A Carpenter, David Jacobsohn, Catherine M Bo...> ;Blood Advances. 2022 Mar 22
3 citations
Immune-Based Therapeutic Interventions for Acute Myeloid Leukemia.
Fabiana Perna, Manuel R Espinoza-Gutarra, Giuseppe Bombaci, Sherif S Farag, Jennifer E Schwartz> ;Cancer Treatment and Research. 2022 Jan 1
8 citations
STEPS to Enhance Physical Activity After Hematopoietic Cell Transplantation for Multiple Myeloma.
Eileen Danaher Hacker, Rae Lee Richards, Mohammad Abu Zaid, Shu Yu Chung, Susan M. Perkins, Sherif S. Farag> ;Cancer Nursing. 2021 Sep 23
3 citations
Meloxicam with Filgrastim may Reduce Oxidative Stress in Hematopoietic Progenitor Cells during Mobilization of Autologous Peripheral Blood Stem Cells in Patients with ...
Andrea M. Patterson, Shuhong Zhang, Liqiong Liu, Hongge Li, Pratibha Singh, Yunlong Liu, Sherif S. Farag, Louis M. Pelus> ;Stem Cell Reviews and Reports. 2021 Sep 12
2 citations
The Brain: Is it a Next Frontier to Better Understand the Regulation and Control of Hematopoiesis for Future Modulation and Treatment?
Hal E. Broxmeyer, Karmen K. Yoder, Yu-Chien Wu, Gary D. Hutchins, Scott Cooper, Sherif S. Farag> ;Stem Cell Reviews and Reports. 2021 Jul 13
3 citations
Effect of family cohesion on symptom distress during hematopoietic stem cell transplantation
Yesol Yang, Wei Pan, Sherif S. Farag, Diane Von Ah> ;Supportive Care in Cancer. 2021 Sep 28
32 citations
Dipeptidyl Peptidase 4 Inhibition for Prophylaxis of Acute Graft-versus-Host Disease
Sherif S. Farag, Mohammad Abu Zaid, Jennifer E. Schwartz, Teresa C Thakrar, Ann J Blakley, Rafat Abonour, Michael J. Robertson, Hal E. Broxmeyer, Shuhong Zhang> ;The New England Journal of Medicine. 2021 Jan 6
1 citations
Effect of Sirolimus levels between days 11 and 20 after allogeneic stem cell transplantation on the risk of hepatic sinusoidal obstruction syndrome.
Vaibhav Agrawal, Praveen Ranganath, Kirsten D. Ervin, Caitlin A. Schmidt, Elizabeth A. Cox, Robert P. Nelson, Jennifer E. Schwartz, Mohammad Abu Zaid, Rafat Abonour, M...> ;Bone Marrow Transplantation. 2021 Jan 1
14 citations
Assessment of ST2 for risk of death following graft-versus-host disease in pediatric and adult age groups.
Courtney M. Rowan, Francis Pike, Kenneth R. Cooke, Robert A. Krance, Paul A. Carpenter, Christine Duncan, David A. Jacobsohn, Catherine M. Bollard, Conrad Russell Y. C...> ;Blood. 2020 Apr 23
30 citations
KIR B donors improve the outcome for AML patients given reduced intensity conditioning and unrelated donor transplantation.
Daniel J. Weisdorf, Sarah Cooley, Tao Wang, Elizabeth A. Trachtenberg, Cynthia Vierra-Green, Stephen R. Spellman, Jennifer A. Sees, Ashley Spahn, Jenny Vogel, Todd A. ...> ;Blood Advances. 2020 Feb 25
3 citations
Histoplasma capsulatum Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient Receiving Voriconazole Prophylaxis.
Vaibhav Agrawal, Bryan J. Brinda, Sherif S. Farag> ;Case Reports in Hematology. 2020 Feb 12
3 citations
Vaccine and Cell-based Therapeutic Approaches in Acute Myeloid Leukemia.
Vaibhav Agrawal, Olumide B. Gbolahan, Maximilian Stahl, Amer M. Zeidan, Mohammad Abu Zaid, Sherif S. Farag, Heiko Konig> ;Current Cancer Drug Targets. 2020 Jan 1
7 citations
Pretransplant HLA typing revealed loss of heterozygosity in the major histocompatibility complex in a patient with acute myeloid leukemia.
Andrew L. Lobashevsky, Mary Krueger-Sersen, Rebecca M. Britton, Courtney A. Littrell, Susmita Singh, Connie P. Cui, Zahra Kashi, Russell K. Martin, Amy M. Breman, Gail...> ;Human Immunology. 2019 Apr 1
5 citations
Low CD34+ Cell Doses Are Associated with Increased Cost and Worse Outcome after Tandem Autologous Stem Cell Transplantation in Patients with Relapsed or Refractory Ger...
Mustafa A. Hyder, W. Scott Goebel, Kirsten D. Ervin, Jennifer E. Schwartz, Michael J. Robertson, Teresa C. Thakrar, Costantine Albany, Sherif S. Farag> ;Biology of Blood and Marrow Transplantation. 2018 Jul 1
8 citations
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
Min Shen, Rosita R. Asawa, Yaqin Zhang, Elizabeth Cunningham, Hongmao Sun, Alexander Tropsha, William P. Janzen, Eugene N. Muratov, Stephen J. Capuzzi, Sherif Farag, A...> ;Oncotarget. 2017 Dec 19
25 citations
High-dose sitagliptin for systemic inhibition of dipeptidylpeptidase-4 to enhance engraftment of single cord umbilical cord blood transplantation
Sherif S. Farag, Robert Nelson, Mitchell S. Cairo, Heather O'Leary, Shuhong Zhang, Carol Huntley, David Delgado, Jennifer E. Schwartz, Mohammad Abu Zaid, Rafat Abonour...> ;Oncotarget. 2017 Nov 27
26 citations
Immunotherapeutic Concepts to Target Acute Myeloid Leukemia: Focusing on the Role of Monoclonal Antibodies, Hypomethylating Agents and the Leukemic Microenvironment
Olumide B. Gbolahan, Amer M. Zeidan, Maximilian Stahl, Mohammad Abu Zaid, Sherif S. Farag, Sophie Paczesny, Heiko Konig> ;International Journal of Molecular Sciences. 2017 Jul 31
11 citations
Preliminary efficacy of a brief family intervention to prevent declining quality of life secondary to parental bone marrow transplantation
Betsy L. Fife, D M Von Ah, Mary L. Spath, Michael T. Weaver, Ziyi Yang, Timothy E. Stump, Sherif S. Farag> ;Bone Marrow Transplantation. 2017 Feb 1
41 citations
Reduced intensity conditioned allograft yields favorable survival for older adults with B-cell acute lymphoblastic leukemia
Ashley E. Rosko, Hai-Lin Wang, Marcos de Lima, Brenda M. Sandmaier, H. Jean Khoury, Andrew S. Artz, Johnathan Brammer, Christopher Bredeson, Sherif Farag, Mohamed A. K...> ;American Journal of Hematology. 2017 Jan 1
4 citations
Killer Cell Immunoglobulin-Like Receptor Ligand Mismatching: To Match or Mismatch?
Sherif S. Farag> ;Biology of Blood and Marrow Transplantation. 2016 Feb 1
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Journal Articles

Pretransplant HLA Typing Revealed Loss of Heterozygosity in the Major Histocompatibility Complex in a Patient with Acute Myeloid Leukemia
Gail H Vance, Andrew L Lobashevsky, Sherif S Farag, ScienceDirect

Press Mentions

Community Health Network Names Medical Director of Stem Cell Transplant and Cellular Therapy ProgramJanuary 25th, 2024

Grant Support

Enhancing Engraftment Of Cord Blood By CD26 InhibitionNational Heart, Lung, And Blood Institute2012
Multiple Kinase Target Inhibition With Emnd-2076 In Multiple MyelomaNational Cancer Institute2010–2011
PathologyNational Cancer Institute2006–2010
Leukemia Tissue BankNational Cancer Institute2005–2009
Qms Technology To Deplete T Cell AlloreactivityNational Institute Of Allergy And Infectious Diseases2006–2008
Qms Technology To Deplete T Cell AlloreactivityNational Institute Of Allergy And Infectious Diseases2004–2005
Mtor Inhibition As A Therapeutic Target In MyelomaNational Cancer Institute2004–2005
NK Cell Recognition Of Leukemia Blasts And IL-2 TherapyNational Cancer Institute2003–2004
Innate Immune Cell Therapy With Stem Cell TransplantsNational Cancer Institute2002–2003