ShridarGanesanMDPhD

PubMed

• Mechanism-centric regulatory network identifies NME2 and MYC programs as markers of Enzalutamide resistance in CRPC.
  Craige, M., Sukanya Panja, Mihai Ioan Truica, Christina Y Yu, Vamshi Saggurthi, Michael W Craige, Katie Whitehead, Mayra V Tuiche, Aymen Al-Saadi, Riddhi Vyas, Shridar...> ;Nature Communications. 2024 Jan 8
• Recurrence-free survival dynamics following adjuvant chemotherapy for resected colorectal cancer: A systematic review of randomized controlled trials.
  Vail, E., Alexander, H., August, D., Berry, A., Boland, P., Haliani, B., Kennedy, T., Maggi, J., Pitt, H., Choubey, A., Eskander, M., Grandhi, M., In, H., Langan, R., ...> ;Cancer Medicine. 2024 Jan 8
• Promoting informed approaches in precision oncology and clinical trial participation for Black patients with cancer: Community-engaged development and pilot testing of...
  Jinghua An, Jeanne M Ferrante, Myneka Macenat, Shridar Ganesan, Shawna V Hudson, Coral Omene, Harold Garcia, Anita Y Kinney> ;Cancer. 2023 Oct 13
• Distinct functions of EHMT1 and EHMT2 in cancer chemotherapy and immunotherapy.
  Zhihua Kang, Pan Fu, Hui Ma, Tao Li, Kevin Lu, Juan Liu, Vasudeva Ginjala, Peter Romanienko, Zhaohui Feng, Ming Guan, Shridar Ganesan, Bing Xia> ;Biorxiv. 2023 Oct 4
• Clonal Hematopoiesis as a Molecular Risk Factor for Doxorubicin-Induced Cardiotoxicity: A Proof-of-Concept Study.
  Jamila Mammadova, Christelle Colin-Leitzinger, Diep Nguyen, Rahul Mhaskar, Shridar Ganesan, Yi-Han Tang, Mingxiang Teng, Roohi Ismail-Khan, Nancy Gillis> ;JCO Precision Oncology. 2023 Sep 1
• Treating Early and Often: Targeted Therapeutics in the Adjuvant Setting.
  Ganesan, S.> ;JCO Precision Oncology. 2023 Sep 1
• 1 citations
  Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer.
  Eduardo Cararo Lopes, Akshada Sawant, Dirk Moore, Hua Ke, Fuqian Shi, Saurabh Laddha, Ying Chen, Anchal Sharma, Jake Naumann, Jessie Yanxiang Guo, Maria Gomez, Maria I...> ;Clinical and Translational Medicine. 2023 Jun 1
• 2 citations
  SOX9 drives KRAS-induced lung adenocarcinoma progression and suppresses anti-tumor immunity.
  Hua Zhong, Wen Lu, Yong Tang, Clotilde Wiel, Yong Wei, Jian Cao, Gregory Riedlinger, Thales Papagiannakopoulos, Jessie Yanxiang Guo, Martin O Bergo, Yibin Kang, Shrida...> ;Oncogene. 2023 Jun 1
• 4 citations
  Computational pathology improves risk stratification of a multi-gene assay for early stage ER+ breast cancer.
  Yuli Chen, Haojia Li, Andrew Janowczyk, Paula Toro, Germán Corredor, Jon Whitney, Cheng Lu, Can F Koyuncu, Mojgan Mokhtari, Christina Buzzy, Shridar Ganesan, Michael D...> ;NPJ Breast Cancer. 2023 May 17
• 3 citations
  Clinical efficacy of PARP inhibitors in breast cancer.
  Karan Pandya, Alyssa Scher, Coral Omene, Shridar Ganesan, Shicha Kumar, Nisha Ohri, Lindsay Potdevin, Bruce Haffty, Deborah L Toppmeyer, Mridula A George> ;Breast Cancer Research and Treatment. 2023 Jul 1
• 1 citations
  Integrated metabolic and genetic analysis reveals distinct features of primary differentiated thyroid cancer and its metastatic potential in humans.
  Eduardo Cararo-Lopes, Akshada Sawant, Dirk Moore, Hua Ke, Fuqian Shi, Saurabh Laddha, Ying Chen, Anchal Sharma, Jake Naumann, Jessie Yanxiang Guo, Maria Gomez, Maria I...> ;Medrxiv. 2023 Mar 10
• Uveitis, a rare but important complication of adjuvant zoledronic acid for early-stage breast cancer.
  Geena Chacko, Srigowri Kota, Shicha Kumar, Nisha Ohri, Coral Omene, Shridar Ganesan, Deborah L Toppmeyer, Mridula A George> ;Anti-Cancer Drugs. 2023 Apr 1
• 10 citations
  Evaluation of Inequities in Cancer Treatment Delay or Discontinuation Following SARS-CoV-2 Infection.
  Adana A M Llanos, Adiba Ashrafi, Nabarun Ghosh, Jennifer Tsui, Yong Lin, Angela J Fong, Shridar Ganesan, Carolyn J Heckman> ;JAMA Network Open. 2023 Jan 3
• 13 citations
  Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.
  Daniel Zingg, Jinhyuk Bhin, Julia Yemelyanenko, Sjors M Kas, Frank Rolfs, Catrin Lutz, Jessica K Lee, Sjoerd Klarenbeek, Ian M Silverman, Stefano Annunziato, Chang S C...> ;Nature. 2022 Sep 1
• 6 citations
  Subtype and cell type specific expression of lncRNAs provide insight into breast cancer.
  Sunniva Stordal Bjørklund, Miriam Ragle Aure, Jari Häkkinen, Johan Vallon-Christersson, Surendra Kumar, Katrine Bull Evensen, Thomas Fleischer, Jörg Tost, , Kristine K...> ;Communications Biology. 2022 Aug 18
• 16 citations
  Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.
  Daniel Zingg, Jinhyuk Bhin, Julia Yemelyanenko, Sjors M Kas, Frank Rolfs, Catrin Lutz, Jessica K Lee, Sjoerd Klarenbeek, Ian M Silverman, Stefano Annunziato, Chang S C...> ;Nature. 2022 Aug 1
• 7 citations
  Genomic landscape of lymphatic malformations: a case series and response to the PI3Kα inhibitor alpelisib in an-of-1 clinical trial.
  Montaser F Shaheen, Julie Y Tse, Ethan S Sokol, Margaret Masterson, Pranshu Bansal, Ian Rabinowitz, Christy A Tarleton, Andrey S Dobroff, Tracey L Smith, Thèrése J Boc...> ;Elife. 2022 Jul 5
• Reply to T. Ménard.
  Nahed Jalloul, Shridar Ganesan, Judy E Garber, Hossein Khiabanian> ;JCO Precision Oncology. 2022 Jun 1
• 3 citations
  Clustered 8-Oxo-Guanine Mutations and Oncogenic Gene Fusions in Microsatellite-Unstable Colorectal Cancer.
  Russell W Madison, Xiaoju Hu, Vivek Ramanan, Zhuxuan Xu, Richard S P Huang, Ethan S Sokol, Garrett M Frampton, Alexa B Schrock, Siraj M Ali, Shridar Ganesan, Subhajyot...> ;JCO Precision Oncology. 2022 May 1
• 1 citations
  Loss of the BRCA1-PALB2 interaction accelerates p53-associated tumor development in mice.
  Amar H Mahdi, Yanying Huo, Ying Chen, Pier Selenica, Anchal Sharma, Elise Merritt, Nicola Barnard, Chang Chan, Shridar Ganesan, Jorge S Reis-Filho, Britta Weigelt, Sub...> ;Genes & Diseases. 2022 May 1
• 64 citations
  Somatic Genomic Testing in Patients With Metastatic or Advanced Cancer: ASCO Provisional Clinical Opinion.
  Debyani Chakravarty, Amber Johnson, Jeffrey Sklar, Neal I Lindeman, Kathleen Moore, Shridar Ganesan, Christine M Lovly, Jane Perlmutter, Stacy W Gray, Jimmy Hwang, Chr...> ;Journal of Clinical Oncology. 2022 Apr 10
• 87 citations
  Real-world application of tumor mutational burden-high (TMB-high) and microsatellite instability (MSI) confirms their utility as immunotherapy biomarkers.
  M Palmeri, J Mehnert, A W Silk, S K Jabbour, S Ganesan, P Popli, G Riedlinger, R Stephenson, A B de Meritens, A Leiser, T Mayer, N Chan, K Spencer, E Girda, J Malhotra...> ;ESMO Open. 2022 Feb 1
• A Gene Panel for Early Identification of Future Responders to Immune Checkpoint Blockade.
  Anshuman Panda, Anil Betigeri, Shridar Ganesan> ;Frontiers in Genetics. 2022 Jan 1
• 10 citations
  Immune Checkpoint Inhibitors in Triple Negative Breast Cancer: The Search for the Optimal Biomarker.
  Sadaf Qureshi, Nancy Chan, Mridula George, Shridar Ganesan, Deborah Toppmeyer, Coral Omene> ;Biomarker Insights. 2022 Jan 1
• 2 citations
  Gene Expression in Barrett’s Esophagus Cell Lines Resemble Esophageal Squamous Cell Carcinoma Instead of Esophageal Adenocarcinoma
  Anshuman Panda, Gyan Bhanot, Shridar Ganesan, Manisha Bajpai> ;Cancers. 2021 Nov 27
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Journal Articles

• RET Rearrangements Are Actionable Alterations in Breast Cancer  
  Shridar Ganesan, Siraj M Ali, Kim M Hirshfield, Nature
• PALB2 Connects BRCA1 and BRCA2 in the G2/M Checkpoint Response  
  Shridar Ganesan, MD, Nature
• Endogenous Retrovirus Expression Is Associated with Response to Immune Checkpoint Blockade in Clear Cell Renal Cell Carcinoma  
  Benjamin G. Vincent, Jonathan S. Serody, Gregory Riedlinger, Shridar Ganesan, The Journal of Clinical Investigation
• High-Throughput Adaptive Sampling for Whole-Slide Histopathology Image Analysis (HASHI) via Convolutional Neural Networks: Application to Invasive Breast Cancer Detection  
  Michael Feldman, Shridar Ganesan, John Tomaszewski, PLoS One
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