SimonKhagiMDFACP
Oncology • Newport Beach, CANeuro-Oncology
Medical Director of Neuro-Oncology | Attending in Medical Oncology and Neurological Oncology
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Office
Hoag Family Cancer Institute
1 Hoag Drive, Building 41
Newport Beach, CA 92663- Is this information wrong?
Summary
- I am a medical neuro-oncologist that specializes in the diagnosis, management, and research of brain and spinal cord tumors. I am board certified in neuro-oncology, medical oncology, and internal medicine. My research interests revolve around the development of novel stem cell-based therapies, neuro-immunotherapeutic techniques, and the implementation of early phase clinical trials.
Education & Training
Duke University HospitalFellowship, Neurological Oncology, 2015 - 2016
Tufts Medical CenterFellowship, Hematology and Medical Oncology, 2012 - 2015
Dartmouth-Hitchcock/Mary Hitchcock Memorial HospitalResidency, Internal Medicine, 2009 - 2012
University of Missouri-Kansas CityBA, Combined and Accelerated BA/MD program, 2002 - 2009
University of Missouri Kansas City School of MedicineClass of 2009- University of Massachusetts Amherst Isenberg School of ManagementMBA, Ongoing
Certifications & Licensure
NH State Medical License 2011 - 2025
CA State Medical License 2023 - 2025
NC State Medical License 2015 - 2021
MA State Medical License 2012 - 2016- American Board of Internal Medicine Medical Oncology
- United Council for Neurologic Subspecialties Neuro-Oncology
Awards, Honors, & Recognition
- Healthcare Hero Head for the Cure Foundation, 2022
- Exemplary Service Award UNC Division of Medical Oncology, 2021
- UNC Hospitals and Faculty Physicians Award for Carolina Care Excellence University of North Carolina Hospitals, 2020
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Clinical Trials
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) Start of enrollment: 2015 Aug 17
- Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients Start of enrollment: 2016 Jul 01
- Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects Start of enrollment: 2016 Oct 06
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Publications & Presentations
PubMed
- 40 citationsOncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial.Farshad Nassiri, Vikas Patil, Leeor S Yefet, Olivia Singh, Jeff Liu, Rachel M A Dang, Takafumi N Yamaguchi, Mariza Daras, Timothy F Cloughesy, Howard Colman, Priya U K...> ;Nature Medicine. 2023 Jun 1
- 117 citationsAssociation of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A P...Linda M Liau, Keyoumars Ashkan, Steven Brem, Jian L Campian, John E Trusheim, Fabio M Iwamoto, David D Tran, George Ansstas, Charles S Cobbs, Jason A Heth, Michael E S...> ;JAMA Oncology. 2023 Jan 1
- 4 citationsResponse to Selpercatinib in a Patient With Recurrent Glioblastoma and RET Amplification.Cameron Czech, Ashley Chen, Katherine P Morgan, Carlos Zamora, Sherif El-Refai, Norleena Poynter, Simon Khagi> ;Journal of the National Comprehensive Cancer Network. 2022 Sep 1
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Journal Articles
- Neuroendocrine Tumors: Treatment UpdatesKhagi S, Saif MW, Journal of the Pancreas
- Pancreatic neuroendocrine tumor with ectopic adrenocorticotropin production: a case report and review of literaturePatel FB, Khagi, S, Anticancer Research, 9/2013
Abstracts/Posters
- Activity of the GlaxoSmithKline kinase inhibitor set on glioblastoma stem cellsKhagi, S., Cochran, B., Sengupta, S, 2015 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Conference, Boston, MA, 11/2015
- An RNAi kinome screen of glioblastomas stem cells under normoxia and hypoxiaGoel-Bhattacharya S, Kulkari S, Sengupta S, Khagi S, Cochran B, Society of Neuro-Oncology Annual Meeting, Miami, FL, 11/2014
- Viridans Streptococcal Carbohydrates and their Salivary Receptor ProteinsKhagi S, Quinn T, Herndon, B, Experimental Biology 2008, San Diego, 4/2008
Other
- Activity of the GlaxoSmithKline kinase inhibitor set on glioblastomas stem cellsKhagi S, Senguta S, Cochran B, CNS Anticancer Drug Discovery and Development Conference (19th Annual SNO Meeting)
https://soc-neuro-onc.conference-services.net/reports/template/onetextabstract.xml?xsl=template/onetextabstract.xsl&conferenceID=4249&abstractID=857962
Miami, FL - 11/2014 - Outcomes Data on the Impact of the Commonwealth Care Initiative on Emergency Department UtilizationKhagi S, Student Research Day 2009
Kansas City, MO - 5/2009
Authored Content
- Fibrin Gel Enhances the Antitumor Effects of Chimeric Antigen Receptor T Cells in GlioblastomaOctober 2021
Press Mentions
Health Watch: Battling Brain Tumors with OptuneNovember 28th, 2018
Battling Brain Tumors with OptuneNovember 21st, 2018
Battling Brain Tumors with OptuneNovember 6th, 2018- Join now to see all
Grant Support
- Ruth L. Kirschstein National Research Service Award T32 FellowshipNational Institutes of Heath2015–2016
- Sarah Morrison Student Research GrantUniversity of Missouri-Kansas City School of Medicine2007–2008
Research History
- Postdoctoral ScholarMolecular physiology and drug discovery research focusing on glioblastoma multiforme at Tufts University.2014 - 2015
Professional Memberships
- Member
- Member
- Member
- Society for Neuro-OncologyMember
- Member
- Member
- UNC Lineberger Comprehensive Cancer CenterMember
- Brain Tumor Trials CollaborativeMember
- Alliance for Clinical Trials in OncologyMember
Other Languages
- Russian
Hospital Affiliations
Hoag Memorial Hospital PresbyterianNewport Beach, California
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