SimonAMahlerMD

Emergency Medicine • Winston Salem, NC

Professor, Emergency Medicine, Wake Forest University School of Medicine

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Office
Medical Center Blvd
Department Of Emergency Medicine
Winston Salem, NC 27157
Phone+1 336-716-2255

Fax+1 336-716-5438
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Education & Training

Wake Forest University School of MedicineResidency, Emergency Medicine, 2002 - 2005
Michigan State University College of Human MedicineClass of 2002

Certifications & Licensure

NC State Medical License 2004 - 2024
LA State Medical License 2005 - 2011
American Board of Emergency Medicine Emergency Medicine

Clinical Trials

Efficacy Evaluation of the HEART Pathway in Emergency Department Patients With Acute Chest Pain Start of enrollment: 2012 Sep 01
Completed
Not Applicable
Cardiac Magnetic Resonance Imaging Strategy for the Management of Patients With Acute Chest Pain and Detectable to Elevated Troponin Start of enrollment: 2013 Sep 01
Completed
Not Applicable
HEART Pathway Implementation Start of enrollment: 2013 Nov 01
Completed
PARA-HEART Pilot Implementation Start of enrollment: 2016 Dec 01
Completed
Study to Evaluate the Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) Plus Standard Medical Treatment (SMT) Versus SMT Alone in Participants in Intensive Care Unit (ICU) With Coronavirus Disease (COVID-19) Start of enrollment: 2020 Sep 17
Completed
Phase 2
Enhancing Rural Health Via Cardiovascular Telehealth for Rural Patients Implementation (E-VICTORS) Start of enrollment: 2021 Feb 01
Recruiting
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Publications & Presentations

PubMed

1 citations
Validation of the ACC Expert Consensus Decision Pathway for Patients With Chest Pain.
Tara Hashemian, Anna C Snavely, Simon A Mahler, Nicklaus P Ashburn, Michael W Supples> ;Journal of the American College of Cardiology. 2024 Apr 2
Performance of the European Society of Cardiology 0/1-hour algorithm with high-sensitivity cardiac troponin T at 90 days among patients with known coronary artery dise...
Snavely, A., Christenson, R., Hashemian, T., Wilkerson, R., Ashburn, N., Allen, B., Madsen, T., McCord, J., Mumma, B., Stopyra, J., Mahler, S.> ;The American Journal of Emergency Medicine. 2024 Feb 23
Safety and Effectiveness of the High-Sensitivity Cardiac Troponin HEART Pathway in Patients With Possible Acute Coronary Syndrome.
Simon A Mahler, Nicklaus P Ashburn, Brennan E Paradee, Jason P Stopyra, James C O'Neill, Anna C Snavely> ;Circulation. Cardiovascular Quality and Outcomes. 2024 Mar 1
Validation of a Novel, Rapid Sepsis Diagnostic for Emergency Department Use.
O'Neal, H., Sheybani, R., Janz, D., Scoggins, R., Jagneaux, T., Walker, J., Henning, D., Rosenman, E., Mahler, S., Regunath, H., Sampson, C., Files, D., Fremont, R., N...> ;Critical Care Explorations. 2024 Feb 1
Rural EMS STEMI Patients - Why the Delay to PCI?
Snavely, A., Brown, W., Stopyra, J., Ashburn, N., Supples, M., Miller, C., Mahler, S.> ;Prehospital Emergency Care. 2024 Jan 18
1 citations
Navigating the Observation Zone: Do Risk Scores Help Stratify Patients With Indeterminate High-Sensitivity Cardiac Troponins?
Nicklaus P Ashburn, James K McCord, Anna C Snavely, Robert H Christenson, Fred S Apple, Richard M Nowak, William F Peacock, Christopher R deFilippi, Simon A Mahler> ;Circulation. 2024 Jan 2
1 citations
Performance of the 0/2-hour high-sensitivity cardiac troponin T diagnostic protocol in a multisite United States cohort.
Michael W Supples, Anna C Snavely, Nicklaus P Ashburn, Brandon R Allen, Robert H Christenson, Richard Nowak, R Gentry Wilkerson, Bryn E Mumma, Troy Madsen, Jason P Sto...> ;Academic Emergency Medicine. 2024 Mar 1
Preventive Cardiovascular Care for Hypercholesterolemia in US Emergency Departments: A National Missed Opportunity.
Nicklaus P Ashburn, Anna C Snavely, Rishi Rikhi, Michael D Shapiro, Michael A Chado, Jason P Stopyra, Simon A Mahler> ;Critical Pathways in Cardiology. 2023 Dec 1
Workplace Health Promotion Programs Available to Emergency Medical Services Clinicians in North Carolina.
Michael W Supples, Joseph S McIlwain, Anna C Snavely, Stephen L Powell, James E Winslow, Jason P Stopyra, Simon A Mahler> ;Prehospital Emergency Care. 2024 Jan 1
1 citations
Emergency Department Observation Unit Patients Want Evaluation and Treatment for Hypercholesterolemia: A Health Belief Model Study.
Nicklaus P Ashburn, Anna C Snavely, Laurie S Stanek, Michael D Shapiro, Rishi R Rikhi, Michael A Chado, Jason P Stopyra, Simon A Mahler> ;Critical Pathways in Cardiology. 2023 Sep 1
1 citations
Race differences in cardiac testing rates for patients with chest pain in a multisite cohort.
Lucas M Popp, Nicklaus P Ashburn, Anna C Snavely, Brandon R Allen, Robert H Christenson, Troy Madsen, Bryn E Mumma, Richard Nowak, Jason P Stopyra, R Gentry Wilkerson,...> ;Academic Emergency Medicine. 2023 Oct 1
1 citations
Rarely tested or treated but highly prevalent: Hypercholesterolemia in ED observation unit patients with chest pain.
Nicklaus P Ashburn, Anna C Snavely, Rishi Rikhi, Michael D Shapiro, Michael A Chado, Alexander P Ambrosini, Amir A Biglari, Spencer T Kitchen, Marissa J Millard, Jason...> ;The American Journal of Emergency Medicine. 2023 Sep 1
Cardiac Magnetic Resonance Imaging Versus Invasive-Based Strategies in Patients With Chest Pain and Detectable to Mildly Elevated Serum Troponin: A Randomized Clinical...
Chadwick D Miller, Simon A Mahler, Anna C Snavely, Subha V Raman, Jeffrey M Caterino, Carol L Clark, Alan E Jones, Michael E Hall, Lauren E Koehler, James F Lovato, Br...> ;Circulation. Cardiovascular Imaging. 2023 Jun 1
1 citations
Personalized diagnosis in suspected myocardial infarction.
Johannes Tobias Neumann, Raphael Twerenbold, Francisco Ojeda, Sally J Aldous, Brandon R Allen, Fred S Apple, Hugo Babel, Robert H Christenson, Louise Cullen, Eleonora ...> ;Clinical Research in Cardiology. 2023 Sep 1
Chest pain observation unit: A missed opportunity to initiate smoking cessation therapy.
Nicklaus P Ashburn, Anna C Snavely, Rishi R Rikhi, Michael A Chado, Weston B Colbaugh, Greg R Noe, Ian J Kinney, Ryan J Morgan, Jason P Stopyra, Simon A Mahler> ;The American Journal of Emergency Medicine. 2023 Jun 1
14 citations
Performance of the European Society of Cardiology 0/1-Hour Algorithm With High-Sensitivity Cardiac Troponin T Among Patients With Known Coronary Artery Disease.
Nicklaus P Ashburn, Anna C Snavely, James C O'Neill, Brandon R Allen, Robert H Christenson, Troy Madsen, Michael R Massoomi, James K McCord, Bryn E Mumma, Richard Nowa...> ;JAMA Cardiology. 2023 Apr 1
Rural and socioeconomic differences in the effectiveness of the HEART Pathway accelerated diagnostic protocol.
James C O'Neill, Nicklaus P Ashburn, Brennan E Paradee, Anna C Snavely, Jason P Stopyra, Greg Noe, Simon A Mahler> ;Academic Emergency Medicine. 2023 Feb 1
Prehospital Comparison of the HEAR and HE-MACS Scores for 30-Day Adverse Cardiac Events.
Lucas M Popp, Nicklaus P Ashburn, Brennan E Paradee, Anna C Snavely, James C O'Neill, Kate M Boyer, Richard Body, Simon A Mahler, Jason P Stopyra> ;Prehospital Emergency Care. 2024 Jan 1
2 citations
Derivation and validation of a high sensitivity troponin-T HEART pathway.
Anna C Snavely, Brennan E Paradee, Nicklaus P Ashburn, Brandon R Allen, Robert Christenson, James C O'Neill, Richard Nowak, R Gentry Wilkerson, Bryn E Mumma, Troy Mads...> ;American Heart Journal. 2023 Feb 1
Response by Ashburn et al. to Letter "CARES".
Nicklaus P Ashburn, Anna C Snavely, Simon A Mahler, Jason P Stopyra> ;Prehospital Emergency Care. 2023 Jan 1
2 citations
Emergency Medical Services Clinicians Have a High Prevalence of Metabolic Syndrome.
Michael W Supples, Nancy K Glober, Thomas A Lardaro, Simon A Mahler, Jason P Stopyra> ;Prehospital Emergency Care. 2023 Jan 1
1 citations
One and Done Epinephrine in Out-of-Hospital Cardiac Arrest? Outcomes in a Multiagency United States Study.
Nicklaus P Ashburn, Bryan P Beaver, Anna C Snavely, Niaman Nazir, James T Winslow, R Darrell Nelson, Simon A Mahler, Jason P Stopyra> ;Prehospital Emergency Care. 2023 Jan 1
21 citations
High-Sensitivity Cardiac Troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guidelines for the Evaluation and Diagnosis of Acute Chest Pain.
Yader Sandoval, Fred S Apple, Simon A Mahler, Richard Body, Paul O Collinson, Allan S Jaffe> ;Circulation. 2022 Aug 16
2 citations
Major adverse cardiac event rates in moderate-risk patients: Does prior coronary disease matter?
Henderson D McGinnis, Nicklaus P Ashburn, Brennan E Paradee, James C O'Neill, Anna C Snavely, Jason P Stopyra, Simon A Mahler> ;Academic Emergency Medicine. 2022 Jun 1
3 citations
Prehospital Time Disparities for Rural Patients with Suspected STEMI.
Jason P Stopyra, Remle P Crowe, Anna C Snavely, Michael W Supples, Nathan Page, Zachary Smith, Nicklaus P Ashburn, Kristie Foley, Chadwick D Miller, Simon A Mahler> ;Prehospital Emergency Care. 2023 Jan 1
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Lectures

High Sensitivity Troponin - Ready for Prime Time?
2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019

Press Mentions

HEART Pathway: Leading in Discovery and Improved CareOctober 15th, 2021
Is It a Heart Attack or Heartburn? This Program Will Let Rural Patients Know Before They Step Foot in the HospitalOctober 19th, 2020
New Approach Helps EMTs Better Assess Chest Pain en Route to HospitalOctober 7th, 2020
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Hospital Affiliations

Atrium Wake Forest BaptistWinston Salem, North Carolina