SpirosLeeBlackburnMD

Cerebrovascular Neurosurgery, Interventional Neuroradiology, Pituitary Surgery

Associate Professor, Neurological Surgery Residency Program Director Co- Director Cerebrovascular and Skull Base Fellowship University of Texas Health Science Center, Houston, TX

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Office
Mischer Neuroscience Institute
6400 Fannin St. Suite 2800
Houston, TX 77030
Phone+1 713-486-8000

Fax+1 713-486-8088
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Education & Training

Washington University/B-JH/SLCH ConsortiumFellowship, Endovascular Surgical Neuroradiology (Radiology), 2011 - 2012
Washington University/B-JH/SLCH ConsortiumResidency, Neurological Surgery, 2004 - 2010
Washington University/B-JH/SLCH ConsortiumInternship, Transitional Year, 2004 - 2005
University of Texas Southwestern Medical SchoolClass of 2004

Certifications & Licensure

TX State Medical License 2015 - 2025
FL State Medical License 2012 - 2016
MO State Medical License Active through 2013
GA State Medical License 2010 - 2011
American Board of Neurological Surgery Neurological Surgery

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Clinical Trials

Framing Eighteen Coils in Cerebral Aneurysms Trial Start of enrollment: 2012 Dec 04
Active, not recruiting
Not Applicable
Safety and Effectiveness of an Intracranial Aneurysm Embolization System for Treating Large or Giant Wide Neck Aneurysms Start of enrollment: 2012 Oct 25
Completed
Not Applicable
Safety Study of Nicardipine to Treat Cerebral Vasospasm Start of enrollment: 2013 Aug 01
Terminated
Phase 2
Association Between Haptoglobin Genotype and Brain Swelling Start of enrollment: 2014 Mar 01
Terminated
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Publications & Presentations

PubMed

Middle meningeal artery embolization reduces recurrence following surgery for septated chronic subdural hematomas.
Juan Carlos Martinez-Gutierrez, Bryden H Dawes, Salvatore A D'Amato, Hyun Woo Kim, Hussein A Zeineddine, William W Wroe, Michael I Nahhas, Peng Roc Chen, Spiros L Blac...> ;Clinical Neurology and Neurosurgery. 2024 Mar 21
Clinical relevance of intracranial hemorrhage after thrombectomy versus medical management for large core infarct: a secondary analysis of the SELECT2 randomized trial.
Michael Chen, Krishna C Joshi, Bradley Kolb, Clark W Sitton, Deep Kiritbhai Pujara, Michael G Abraham, Santiago Ortega-Gutierrez, Scott E Kasner, Shazam M Hussain, Leo...> ;Journal of Neurointerventional Surgery. 2024 Mar 12
Red Blood Cells in the Cerebrospinal Fluid Compartment After Subarachnoid Haemorrhage: Significance and Emerging Therapeutic Strategies.
Soham Bandyopadhyay, Nina Schwendinger, Behnam Rezai Jahromi, Shivanand P Lad, Spiros Blackburn, Stefan Wolf, Diederik Bulters, Ian Galea, Michael Hugelshofer> ;Translational Stroke Research. 2024 Feb 29
2 citations
The VEBAS score: a practical scoring system for intracranial dural arteriovenous fistula obliteration.
Becerril-Gaitan, A., Ding, D., Ironside, N., Buell, T., Kansagra, A., Lanzino, G., Brinjikji, W., Kim, L., Levitt, M., Abecassis, I., Bulters, D., Durnford, A., Fox, W...> ;Journal of Neurointerventional Surgery. 2024 Feb 12
Endovascular Thrombectomy Treatment Effect in Direct vs Transferred Patients With Large Ischemic Strokes: A Prespecified Analysis of the SELECT2 Trial.
Khan, M. A., Amrou Sarraj, Michael D Hill, M Shazam Hussain, Michael G Abraham, Santiago Ortega-Gutierrez, Michael Chen, Scott E Kasner, Leonid Churilov, Deep K Pujara...> ;JAMA Neurology. 2024 Feb 8
2 citations
Endovascular thrombectomy plus medical care versus medical care alone for large ischaemic stroke: 1-year outcomes of the SELECT2 trial.
Sarraj, A., Abraham, M., Hassan, A., Blackburn, S., Kasner, S., Ortega-Gutierrez, S., Hussain, M., Chen, M., Johns, H., Churilov, L., Pujara, D., Shaker, F., Maali, L....> ;Lancet. 2024 Feb 24
1 citations
Endovascular Thrombectomy for Large Ischemic Stroke Across Ischemic Injury and Penumbra Profiles.
Khan, M. A., Amrou Sarraj, Ameer E Hassan, Michael G Abraham, Santiago Ortega-Gutierrez, Scott E Kasner, Muhammad Shazam Hussain, Michael Chen, Leonid Churilov, Hannah...> ;JAMA. 2024 Mar 5
Neutrophils and Neutrophil Extracellular Traps Cause Vascular Occlusion and Delayed Cerebral Ischemia After Subarachnoid Hemorrhage in Mice.
Hong, S., Peesh, P., Dienel, A., Torres, K., Thankamani Pandit, P., Matsumura, K., Huang, S., Li, W., Chauhan, A., Marrelli, S., Aronowski, J., McBride, D., Zeineddine...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2024 Mar 1
2 citations
Cerebrovascular Complications Associated With Iatrogenic Fungal Meningitis Following Surgical Procedures in Mexico.
Andrea Becerril-Gaitan, Shivani Bindal, Samantha L Parker, Hussein A Zeineddine, Justine M Chen, Huimahn A Choi, Peng R Chen, Spiros Blackburn, Arthur Day, Robert J Br...> ;Stroke. 2024 Jan 1
A Transcriptomic Comparative Study of Cranial Vasculature.
Jianing Zhang, Jee-Yeon Ryu, Selena-Rae Tirado, Lawrence D Dickinson, Aviva Abosch, M Ali Aziz-Sultan, Alan S Boulos, Daniel L Barrow, H Hunt Batjer, Tamar R Binyamin,...> ;Translational Stroke Research. 2023 Aug 23
1 citations
Middle meningeal artery embolization of septated chronic subdural hematomas.
Juan Carlos Martinez-Gutierrez, Salvatore A D'Amato, Hussein A Zeineddine, Michael I Nahhas, Matthew J Kole, Hyun Woo Kim, Youngran Kim, Bryden H Dawes, Peng Roc Chen,...> ;Interventional Neuroradiology. 2023 Jun 26
Antiplatelet and anticoagulation therapy and the risk of pituitary apoplexy in pituitary adenoma patients.
Bronson Ciavarra, Timothy McIntyre, Matthew J Kole, Wen Li, William Yao, Katie B Guttenberg, Spiros L Blackburn> ;Pituitary. 2023 Aug 1
1 citations
Subarachnoid Blood Clearance and Aneurysmal Subarachnoid Hemorrhage Outcomes: A Retrospective Review.
Hussein A Zeineddine, Anthony Divito, Devin W McBride, Peeyush Pandit, Stephen Capone, Bryden H Dawes, James C Grotta, Spiros L Blackburn, Chen, C.> ;Neurocritical Care. 2023 Aug 1
Neurofibroma of the internal carotid artery cavernous sympathetic plexus: illustrative case.
Duncan J Trimble, Bryden H Dawes, Hussein A Zeineddine, Katie B Guttenberg, William C Yao, Meenakshi Bhattacharjee, Spiros L Blackburn> ;Journal of Neurosurgery. Case Lessons. 2023 Apr 17
20 citations
Association of Endovascular Thrombectomy vs Medical Management With Functional and Safety Outcomes in Patients Treated Beyond 24 Hours of Last Known Well: The SELECT L...
Amrou Sarraj, Timothy J Kleinig, Ameer E Hassan, Pere Cardona Portela, Santiago Ortega-Gutierrez, Michael G Abraham, Nathan W Manning, James E Siegler, Nitin Goyal, La...> ;JAMA Neurology. 2023 Feb 1
4 citations
Mediation of Successful Reperfusion Effect through Infarct Growth and Cerebral Edema: A Pooled, Patient-Level Analysis of EXTEND-IA Trials and SELECT Prospective Cohort.
Amrou Sarraj, Deep K Pujara, Leonid Churilov, Clark W Sitton, Felix Ng, Ameer E Hassan, Michael G Abraham, Spiros L Blackburn, Gagan Sharma, Nawaf Yassi, Timothy Klein...> ;Annals of Neurology. 2023 Apr 1
2 citations
Evidence-based interconversion of the Glasgow Outcome and modified Rankin scales: pitfalls and best practices.
Ben Gaastra, Dianxu Ren, Sheila Alexander, Issam A Awad, Spiros Blackburn, Sylvain Doré, Dan Hanley, Paul Nyquist, Diederik Bulters, Ian Galea> ;Journal of Stroke and Cerebrovascular Diseases. 2022 Dec 1
4 citations
Middle Meningeal Artery Embolization for Chronic Subdural Hematomas With Concurrent Antithrombotics.
Juan Carlos Martinez-Gutierrez, Hussein A Zeineddine, Michael I Nahhas, Matthew J Kole, Youngran Kim, Hyun Woo Kim, Salvatore A D'Amato, Peng Roc Chen, Spiros L Blackb...> ;Neurosurgery. 2023 Feb 1
2 citations
Thrombectomy Outcomes With General vs Nongeneral Anesthesia: A Pooled Patient-Level Analysis From the EXTEND-IA Trials and SELECT Study.
Amrou Sarraj, Gregory W Albers, Peter J Mitchell, Ameer E Hassan, Michael G Abraham, Spiros Blackburn, Gagan Sharma, Nawaf Yassi, Timothy J Kleinig, Darshan G Shah, Te...> ;Neurology. 2023 Jan 17
1 citations
A Genome-Wide Association Study of Outcome After Aneurysmal Subarachnoid Haemorrhage: Discovery Analysis.
Ben Gaastra, Sheila Alexander, Mark K Bakker, Hemant Bhagat, Philippe Bijlenga, Spiros L Blackburn, Malie K Collins, Sylvain Doré, Christoph J Griessenauer, Philipp He...> ;Translational Stroke Research. 2023 Oct 1
2 citations
Wide-Necked Middle Cerebral Artery Aneurysm Clipping Following Failed Occlusion After Woven EndoBridge Placement: 2-Dimensional Operative Video.
Stephen Capone, Anil Roy, Matthew Kole, Spiros L Blackburn> ;Operative Neurosurgery. 2022 Oct 1
4 citations
Genome-Wide Association Study of Clinical Outcome After Aneurysmal Subarachnoid Haemorrhage: Protocol.
Ben Gaastra, Sheila Alexander, Mark K Bakker, Hemant Bhagat, Philippe Bijlenga, Spiros Blackburn, Malie K Collins, Sylvain Doré, Christoph Griessenauer, Philipp Hendri...> ;Translational Stroke Research. 2022 Aug 1
1 citations
Glyoxal Fixation Is Optimal for Immunostaining of Brain Vessels, Pericytes and Blood-Brain Barrier Proteins.
Sithara Thomas, Jayanarayanan Sadanandan, Spiros L Blackburn, Devin W McBride, Ari Dienel, Sungha Hong, Hussein A Zeineddine, Peeyush Kumar Thankamani> ;International Journal of Molecular Sciences. 2022 Jul 14
1 citations
Thromboelastography Indices for Predicting Outcomes After Aneurysmal Subarachnoid Hemorrhage: A Prospective Study.
Hussein A Zeineddine, Wen Li, Peeyush Kumar T, Devin McBride, Ari Dienel, Glenda Torres, James Grotta, Jude Savarraj, Tiffany Chang, Huimahn A Choi, Pramod Dash, Spiro...> ;Stroke. 2022 Jun 1
10 citations
Thrombectomy versus Medical Management in Mild Strokes due to Large Vessel Occlusion: Exploratory Analysis from the EXTEND-IA Trials and a Pooled International Cohort.
Amrou Sarraj, Gregory W Albers, Jordi Blasco, Juan F Arenillas, Marc Ribo, Ameer E Hassan, Natalia Pérez de la Ossa, Teddy Yuan-Hao Wu, Pere Cardona Portela, Michael G...> ;Annals of Neurology. 2022 Sep 1
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Press Mentions

'It's Fun to Cheat Death': This UT Freshman Had a Blood Clot the Size of an Apple in His SkullMarch 24th, 2021
Two Studies Reveal Pregnant Women Bear Greater Risk of Hemorrhagic StrokeFebruary 7th, 2019
Minnetronix Neuro Successfully Completes First Clinical Study in Hemorrhagic StrokeOctober 1st, 2018