StevenGrantMD

PubMed

• Venetoclax with decitabine or azacitidine in relapsed or refractory acute myeloid leukemia.
  Murray, G., Doyel, M., Patel, T., Boron, J., Hang, Y., Ho, T., Zacholski, K., Venn, C., Wages, N., Bouligny, I., Tran, V., Gor, J., Alnimer, Y., Grant, S., Maher, K.> ;Medical Oncology. 2024 Feb 23
• Azaphosphinate Dyes: A Low Molecular Weight Near-Infrared Scaffold for Development of Photoacoustic or Fluorescence Imaging Probes.
  Ruwen Yin, Frederik Brøndsted, Lin Li, Julia L McAfee, Yuan Fang, Joshua S Sykes, Yuchen He, Steven Grant, Jiang He, Cliff I Stains> ;Chemistry. 2024 Mar 15
• 1 citations
  Single Atom Stabilization of Phosphinate Ester-Containing Rhodamines Yields Cell Permeable Probes for Turn-On Photoacoustic Imaging.
  Frederik Brøndsted, Yuan Fang, Lin Li, Xinqi Zhou, Steven Grant, Cliff I Stains> ;Chemistry. 2024 Jan 2
• Abbreviated venetoclax with decitabine or azacitidine in acute myeloid leukemia.
  Ian M Bouligny, Graeme Murray, Thuy Ho, Michael Doyel, Tilak Patel, Josh Boron, Valerie Tran, Juhi Gor, Yiwei Hang, Yanal Alnimer, Kyle Zacholski, Chad Venn, Nolan A W...> ;Leukemia Research. 2023 Nov 1
• Secondary-Type Mutations in Acute Myeloid Leukemia: Updates from ELN 2022.
  Ian M Bouligny, Keri R Maher, Steven Grant> ;Cancers. 2023 Jun 22
• Venetoclax with Decitabine or Azacitidine in Relapsed or Refractory Acute Myeloid Leukemia.
  Ian M Bouligny, Graeme Murray, Thuy Ho, Michael Doyel, Tilak Patel, Josh Boron, Valerie Tran, Juhi Gor, Yiwei Hang, Yanal Alnimer, Kyle Zacholski, Chad Venn, Nolan A W...> ;Research Square. 2023 Jun 12
• 5 citations
  Venetoclax with decitabine or azacitidine in the first-line treatment of acute myeloid leukemia.
  Ian M Bouligny, Graeme Murray, Michael Doyel, Tilak Patel, Josh Boron, Valerie Tran, Juhi Gor, Yiwei Hang, Yanal Alnimer, Kyle Zacholski, Chad Venn, Nolan A Wages, Ste...> ;Ejhaem. 2023 May 1
• Non-canonical role for the ataxia-telangiectasia-Rad3 pathway in STAT3 activation in human multiple myeloma cells.
  Lin Li, Xiaoyan Hu, Jewel Nkwocha, Kanika Sharma, Maciej Kmieciak, Hashim Mann, Liang Zhou, Steven Grant> ;Cellular Oncology. 2023 Oct 1
• 3 citations
  Phase 1 study of belinostat and adavosertib in patients with relapsed or refractory myeloid malignancies.
  Danielle Shafer, Amanda B Kagan, Michelle A Rudek, Maciej Kmieciak, Mary Beth Tombes, Ellen Shrader, Dipankar Bandyopadhyay, Daniel Hudson, Heidi Sankala, Caryn Weir, ...> ;Cancer Chemotherapy and Pharmacology. 2023 Mar 1
• 1 citations
  Synergistic Interactions between the Hypomethylating Agent Thio-Deoxycytidine and Venetoclax in Myelodysplastic Syndrome Cells.
  Xiaoyan Hu, Lin Li, Jewel Nkwocha, Kanika Sharma, Liang Zhou, Steven Grant> ;Hematology Reports. 2023 Feb 2
• 2 citations
  Dual mTORC1/2 Inhibition Synergistically Enhances AML Cell Death in Combination with the BCL2 Antagonist Venetoclax.
  Toshihisa Satta, Lin Li, Sri Lakshmi Chalasani, Xiaoyan Hu, Jewel Nkwocha, Kanika Sharma, Maciej Kmieciak, Mohamed Rahmani, Liang Zhou, Steven Grant> ;Clinical Cancer Research. 2023 Apr 3
• 2 citations
  The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence.
  Christiana O Appiah, Manjulata Singh, Lauren May, Ishita Bakshi, Ashish Vaidyanathan, Paul Dent, Gordon Ginder, Steven Grant, Harry Bear, Joseph Landry> ;Advances in Cancer Research. 2023 Jan 1
• 4 citations
  Augmenting Venetoclax Activity Through Signal Transduction in AML.
  Ian Michael Bouligny, Keri Renee Maher, Steven Grant> ;Journal of Cellular Signaling. 2023 Jan 1
• Functional role of DNMT1 in the anti-leukemic effects of hypomethylating agents in AML cells.
  Lin Li, Xiaoyan Hu, Jewel Nkwocha, Kanika Sharma, Liang Zhou, Steven Grant> ;Leukemia Research. 2022 Oct 1
• 11 citations
  Mechanisms of myeloid leukemogenesis: Current perspectives and therapeutic objectives.
  Ian M Bouligny, Keri R Maher, Steven Grant> ;Blood Reviews. 2023 Jan 1
• 2 citations
  Mechanisms underlying synergism between circularized tumor necrosis factor-related apoptosis inducing ligand and bortezomib in bortezomib-sensitive or -resistant myelo...
  Yun Leng, Xiaoyan Hu, Lin Li, Jewel Nkwocha, Toshihisa Satta, Kanika Sharma, Maciej Kmeiciak, Huixing Zhou, Zhiyao Zhang, Liang Zhou, Wenming Chen, Steven Grant> ;Hematological Oncology. 2022 Dec 1
• 3 citations
  Chk1 inhibition potently blocks STAT3 tyrosine705 phosphorylation, DNA binding activity, and activation of downstream targets in human multiple myeloma cells.
  Liang Zhou, Xin-Yan Pei, Yu Zhang, Yanxia Ning, Lin Li, Xiaoyan Hu, Sri Lakshmi Chalasani, Kanika Sharma, Jewel Nkwocha, Jonathan Yu, Dipankar Bandyopadhyay, Said M. S...> ;Molecular Cancer Research. 2021 Nov 15
• 10 citations
  IAP and HDAC inhibitors interact synergistically in myeloma cells through noncanonical NF-κB- and caspase-8-dependent mechanisms.
  Liang Zhou, Yu Zhang, Mark B. Meads, Yun Dai, Yanxia Ning, Xiaoyan Hu, Lin Li, Kanika Sharma, Jewel Nkwocha, Rebecca E. Parker, Danny Bui, Jacquelyn McCarter, Lora Kra...> ;Blood Advances. 2021 Oct 12
• 2 citations
  Targeting cereblon in AML
  Steven Grant> ;Blood. 2021 Feb 4
• 3 citations
  Phase 1 study of belinostat (PXD-101) and bortezomib (Velcade, PS-341) in patients with relapsed or refractory acute leukemia and myelodysplastic syndrome.
  Beata Holkova, Danielle Shafer, Victor Yazbeck, Sandeep S. Dave, Prithviraj Bose, Mary Beth Tombes, Ellen Shrader, Wen Wan, Dipankar Bandyopadhyay, Caryn Weir, Elizabe...> ;Leukemia & Lymphoma. 2021 Apr 16
• 6 citations
  Enhancing venetoclax activity in hematological malignancies
  Toshihisa Satta, Steven Grant> ;Expert Opinion on Investigational Drugs. 2020 Jul 16
• 5 citations
  Recruiting TP53 to target chronic myeloid leukemia stem cells.
  Steven Grant> ;Haematologica. 2020 May 1
• 76 citations
  Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models
  Lina Han, Qi Zhang, Monique Dail, Ce Shi, Antonio Cavazos, Vivian Ruvolo, Yang Zhao, Eugene Kim, Mohamed Rahmani, Duncan H. Mak, Sha S. Jin, Jun Chen, Darren C. Philli...> ;Haematologica. 2020 Mar 1
• 33 citations
  The Covalent CDK7 Inhibitor THZ1 Potently Induces Apoptosis in Multiple Myeloma Cells In Vitro and In Vivo.
  Yu Zhang, Liang Zhou, Dipankar Bandyopadhyay, Kanika Sharma, Alexander Allen, Maciej Kmieciak, Steven Grant> ;Clinical Cancer Research. 2019 Oct 15
• 1 citations
  Correction: Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin's lymphoma cells occurandand proceed through multiple mechanisms.
  Tri Nguyen, Rebecca Parker, Elisa Hawkins, Beata Holkova, Victor Yazbeck, Akhil Kolluri, Maciej Kmieciak, Mohamed Rahmani, Steven Grant> ;Oncotarget. 2019 Sep 3
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