TimothyD.BigbyMD

PubMed

• Cigarette Smoke Triggers IL-33-associated Inflammation in a Model of Late-Stage Chronic Obstructive Pulmonary Disease.
  Lee, J. H., Hailey, K. L., Vitorino, S. A., Jennings, P. A., Bigby, T. D., Breen, E. C.> ;American journal of respiratory cell and molecular biology. 2019 Apr 12
• Small Molecule Mimetics of α-Helical Domain of IRAK2 Attenuate the Proinflammatory Effects of IL-33 in Asthma-like Mouse Models.
  Li, J., Saruta, K., Dumouchel, J. P., Magat, J. M., Thomas, J. L., Ajami, D., Rebek, M., Rebek, J., Bigby, T. D.> ;Journal of immunology (Baltimore, Md. : 1950). 2018 May 8
• Functional magnetic resonance imaging for in vivo quantification of pulmonary hypertension in the Sugen 5416/hypoxia mouse.
  Breen, E. C., Scadeng, M., Lai, N. C., Murray, F., Bigby, T. D.> ;Experimental physiology. 2016 Nov 30
• 15 citations
  Cobinamide is superior to other treatments in a mouse model of cyanide poisoning.
  Chan, A., Balasubramanian, M., Blackledge, W., Mohammad, O. M., Alvarez, L., Boss, G. R., Bigby, T. D.> ;Clinical toxicology (Philadelphia, Pa.). 2010 Aug 14
• 2 citations
  Innate Immunity and Asthma
  Patricia W. Finn, Timothy D. Bigby> ;Proceedings of the American Thoracic Society. 2009 May 1
• Nitrosyl-Cobinamide, a New and Direct Nitric Oxide–Releasing Drug Effective In Vivo
  Kate E. Broderick, Luis Alvarez, Mahesh Balasubramanian, Darrell D. Belke, Ayako Makino, Adriano Chan, Virgil L. Woods, Wolfgang H. Dillmann, Vijay S. Sharma, Renate B...> ;Experimental Biology and Medicine. 2007 Dec 1
• 16 citations
  The cobalamin precursor cobinamide detoxifies nitroprusside-generated cyanide.
  Broderick, K. E., Balasubramanian, M., Chan, A., Potluri, P., Feala, J., Belke, D. D., McCulloch, A. D., Sharma, V. S., Pilz, R. B., Bigby, T. D., Boss, G. R.> ;Experimental biology and medicine (Maywood, N.J.). 2007 May 29
• Intranasal ketorolac challenge for the diagnosis of aspirin-exacerbated respiratory disease
  Andrew A. White, Timothy D. Bigby, Donald D. Stevenson> ;Annals of Allergy Asthma & Immunology. 2006 Aug 1
• Allergen-independent immunostimulatory sequence oligodeoxynucleotide therapy attenuates experimental allergic rhinitis.
  Chae-Seo Rhee, Lev Libet, Dugald Chisholm, Kenji Takabayashi, Stephen M. Baird, Timothy D. Bigby, Chul Hee Lee, Anthony A. Horner, Eyal Raz> ;Immunology. 2004 Sep 1
• Mechanisms of Glomerular Immune Injury: Effects of Antioxidant Treatment
  Sriram S. Narsipur, Orjan W. Peterson, Robert C. Smith, Timothy D. Bigby, Sampath Parthasarathy, Francis B. Gabbai, Curtis B. Wilson, Roland C. Blantz> ;Journal of The American Society of Nephrology. 2003 Jul 1
• 5-Lipoxygenase-activating Protein Gene Expression KEY ROLE OF CCAAT/ENHANCER-BINDING PROTEINS (C/EBP) IN CONSTITUTIVE AND TUMOR NECROSIS FACTOR (TNF) α-INDUCED EXPRESS...
  K. Veera Reddy, Kenneth J. Serio, Craig R. Hodulik, Timothy D. Bigby> ;Journal of Biological Chemistry. 2003 Apr 18
• 4 citations
  Lipopolysaccharide Down-Regulates the Leukotriene C4 Synthase Gene in the Monocyte-Like Cell Line, THP-1
  Kenneth J. Serio, Scott C. Johns, Linda Luo, Craig R. Hodulik, Timothy D. Bigby> ;Journal of Immunology. 2003 Feb 15
• What about the role of the US Food and Drug Administration?
  Bigby, B. G., Bigby, T. D.> ;Chest. 2002 Nov 12
• 1 citation
  The leukotriene C(4) synthase gene and asthma.
  Bigby, T. D.> ;American journal of respiratory cell and molecular biology. 2000 Sep 6
• 24 citations
  Pulmonary Infiltrates, Eosinophilia, and Cardiomyopathy Following Corticosteroid Withdrawal in Patients With Asthma Receiving Zafirlukast
  Michael E. Wechsler, Erik Garpestad, Steven R. Flier, Olivier Kocher, David A. Weiland, Albert J. Polito, Michelle M. Klinek, Timothy D. Bigby, Gordon A. Wong, Richard...> ;JAMA. 1998 Feb 11
• 8 citations
  Activated lymphocytes increase expression of 5-lipoxygenase and its activating protein in THP-1 cells.
  Ring, W. L., Riddick, C. A., Baker, J. R., Glass, C. K., Bigby, T. D.> ;American journal of physiology. Cell physiology. 1997 Dec 1
• 2 citations
  Diagnosis of Pneumocystis carinii pneumonia. How invasive?
  Bigby, T. D.> ;Chest. 1994 Mar 1
• The intestinal epithelium: A participant in as well as the target of inflammation?
  Kim E. Barrett, Timothy D. Bigby> ;Gastroenterology. 1993 Jul 1
• Involvement of arachidonic acid in the chloride secretory response of intestinal epithelial cells
  Kim E. Barrett, Timothy D. Bigby> ;American Journal of Physiology-cell Physiology. 1993 Feb 1
• Effect of macrophage stimulation on parasympathetic airway contraction in dogs.
  Tamaoki, J., Sekizawa, K., Ueki, I. F., Graf, P. D., Nadel, J. A., Bigby, T. D.> ;European journal of pharmacology. 1987 Jun 26
• 10 citations
  Clinical spectrum of pulmonary mucormycosis.
  Bigby, T. D., Serota, M. L., Tierney, L. M., Matthay, M. A.> ;Chest. 1986 Mar 1
• Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis.
  Jiang, Z., Georgel, P., Li, C., Choe, J., Crozat, K., Rutschmann, S., Du, X., Bigby, T., Mudd, S., Sovath, S., Wilson, I. A., Olson, A., Beutler, B.> ;Proc Natl Acad Sci U S A. 2006 Jul 18
• Sp1 and Sp3 function as key regulators of leukotriene C(4) synthase gene expression in the monocyte-like cell line, THP-1.
  Serio, K. J., Hodulik, C. R., Bigby, T. D.> ;Am J Respir Cell Mol Biol. 2000 Aug
• Regulation of expression of the 5-lipoxygenase pathway.
  Bigby, T. D.> ;Clin Rev Allergy Immunol.
• TGF-beta increases leukotriene C4 synthase expression in the monocyte-like cell line, THP-1.
  Riddick, C. A., Serio, K. J., Hodulik, C. R., Ring, W. L., Regan, M. S., Bigby, T. D.> ;J Immunol. 1999 Jan 15
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