ToddDavidGreenMD

Pediatric Asthma & Allergic Conditions

Associate Professor, Pediatrics, University of Pittsburgh School of Medicine Director, Food Allergy Center, Children's Hospital of Pittsburgh of UPMC

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Office
4401 Penn Avenue
Bldg 1
Pittsburgh, PA 15224
Phone+1 412-647-3087

Fax+1 412-647-4486
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Education & Training

Duke University HospitalFellowship, Allergy and Immunology, 2004 - 2006
Maine Medical CenterResidency, Pediatrics, 2001 - 2004
University of Pittsburgh School of MedicineClass of 2001

Certifications & Licensure

PA State Medical License 2006 - 2024
WV State Medical License 2015 - 2018
NC State Medical License 2004 - 2006
American Board of Allergy and Immunology Allergy & Immunology

Awards, Honors, & Recognition

Fellow (FAAAAI) American Academy of Allergy Asthma and Immunology

Clinical Trials

Mechanisms of Immune Tolerance and Inflammation in Patients With Cystic Fibrosis With ABPA Start of enrollment: 2005 Mar 01
Completed
Observational Safety Study for KALBITOR (Ecallantide) in the Treatment of Acute Attacks of Hereditary Angioedema Start of enrollment: 2010 Feb 01
Completed
Safe Administration of Flu Vaccine to Egg Allergic Children Start of enrollment: 2010 Oct 01
Completed
Not Applicable
TransMEM Gas Exchange -- Project 1, Aim 2 Start of enrollment: 2013 Oct 01
Completed
Phase 1
Efficacy and Safety of Viaskin Milk in Children With IgE-Mediated Cow's Milk Allergy Start of enrollment: 2014 Nov 01
Completed
Phase 1, Phase 2
Efficacy and Safety of Viaskin Peanut in Children With Immunoglobulin E (IgE)-Mediated Peanut Allergy Start of enrollment: 2015 Dec 01
Completed
Phase 3
Follow-up of the PEPITES Study to Evaluate Long-term Efficacy and Safety of Viaskin Peanut in Children Start of enrollment: 2017 Jan 23
Active, not recruiting
Phase 3
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Publications & Presentations

PubMed

14 citations
Phase 3 Trial of Epicutaneous Immunotherapy in Toddlers with Peanut Allergy.
Matthew Greenhawt, Sayantani B Sindher, Julie Wang, Michael O'Sullivan, George du Toit, Edwin H Kim, Deborah Albright, Sara Anvari, Nicolette Arends, Peter D Arkwright...> ;The New England Journal of Medicine. 2023 May 11
1 citations
The Impact of Allergy Specialty Care on Health Care Utilization Among Peanut Allergy Children in the United States.
Matthew Greenhawt, Elissa M Abrams, Joseph M Chalil, Oth Tran, Todd D Green, Marcus S Shaker> ;The Journal of Allergy and Clinical Immunology. in Practice. 2022 Dec 1
1 citations
Peanut cross-contamination in randomly selected baked goods.
Travis A Miller, Stef J Koppelman, J Andrew Bird, Vivian Hernandez-Trujillo, Ananth Thyagarajan, Douglas Mack, Joseph M Chalil, Todd D Green, Joseph L Baumert> ;Annals of Allergy, Asthma & Immunology. 2022 Apr 1
18 citations
Safety of Epicutaneous Immunotherapy in Peanut-Allergic Children: REALISE Randomized Clinical Trial Results.
Jacqueline A. Pongracic, Remi Gagnon, Gordon Sussman, Dareen Siri, Roxanne C. Oriel, Terri F. Brown-Whitehorn, Todd D. Green, Dianne E. Campbell, Sara Anvari, William ...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2021 Nov 27
2 citations
Reduction in peanut reaction severity during oral challenge after 12 months of epicutaneous immunotherapy.
Philippe Bégin, John Andrew Bird, Jonathan M. Spergel, Dianne E. Campbell, Todd D. Green, Katharine J Bee, Romain Lambert, Hugh A. Sampson, David Fleischer> ;Allergy. 2021 Sep 7
2 citations
Predicted number of peanut-allergic patients needed to treat with epicutaneous immunotherapy (EPIT) to prevent one allergic reaction: A novel approach to assessing rel...
Benjamin C. Remington, Stef J. Koppelman, Todd D. Green, Gideon Lack, Graham Roberts, Dianne E. Campbell> ;Allergy. 2021 Jun 2
1 citations
Post hoc analysis of epicutaneous immunotherapy for peanut allergy phase 3 results: Relevance for exposure through restaurant meals.
Benjamin C. Remington, Dianne E. Campbell, Todd D. Green, David Fleischer, Stef J. Koppelman> ;Annals of Allergy, Asthma & Immunology. 2021 Feb 1
6 citations
Sustained unresponsiveness to peanut after long-term peanut epicutaneous immunotherapy
Terri F. Brown-Whitehorn, Frédéric de Blay, Jonathan M. Spergel, Todd D. Green, Aurélie Peillon, Hugh A. Sampson, Dianne E. Campbell> ;The Journal of Allergy and Clinical Immunology. in Practice. 2021 Jan 1
24 citations
Improvements in Quality of Life in Children Following Epicutaneous Immunotherapy (EPIT) for Peanut Allergy in the PEPITES and PEOPLE Studies.
Audrey DunnGalvin, David Fleischer, Dianne E. Campbell, Jonathan O'b Hourihane, Todd D. Green, Hugh A. Sampson, Matthew Greenhawt> ;The Journal of Allergy and Clinical Immunology. in Practice. 2021 Jan 1
38 citations
Long-term, open-label extension study of the efficacy and safety of epicutaneous immunotherapy for peanut allergy in children: PEOPLE 3-year results
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;The Journal of Allergy and Clinical Immunology. 2020 Oct 1
3 citations
An evaluation of factors influencing response to epicutaneous immunotherapy for peanut allergy in the PEPITES trial.
David Fleischer, Sharon Chinthrajah, Amy M. Scurlock, Dianne E. Campbell, T. Green, Katharine J Bee, Aurélie Peillon, Terrance Ocheltree, Hugh A. Sampson> ;Allergy and Asthma Proceedings. 2020 Sep 1
7 citations
Evaluation of daily patch application duration for epicutaneous immunotherapy for peanut allergy.
David Fleischer, Jonathan M. Spergel, Edwin H. Kim, Dianne E. Campbell, T. Green, Katharine J Bee, Romain Lambert, Terrance Ocheltree, Hugh A. Sampson> ;Allergy and Asthma Proceedings. 2020 Jul 1
7 citations
Improvements in eliciting dose across baseline sensitivities following 12 months of epicutaneous immunotherapy (EPIT) in peanut-allergic children aged 4 to 11 years.
Matthew Greenhawt, Edwin H. Kim, Dianne E. Campbell, Todd D. Green, Romain Lambert, David Fleischer> ;The Journal of Allergy and Clinical Immunology. in Practice. 2020 Jun 2
7 citations
Managing food protein-induced enterocolitis syndrome during the coronavirus disease 2019 pandemic: Expert recommendations.
Anna Nowak-Wegrzyn, Antonella Cianferoni, John Andrew Bird, Alessandro Fiocchi, Jean-Christoph Roger J-P Caubet, Stefania Arasi, Ashis V. Barad, Theresa Bingemann, Ter...> ;Annals of Allergy, Asthma & Immunology. 2020 May 5
15 citations
Unmet needs of children with peanut allergy: Aligning the risks and the evidence.
Edmond S. Chan, Chitra Dinakar, Erika Gonzales-Reyes, Todd D. Green, Ruchi Gupta, Douglas H. Jones, Julie Wang, Tonya Winders, Matthew Greenhawt> ;Annals of Allergy, Asthma & Immunology. 2020 Jan 30
12 citations
Commercial claims costs related to health care resource use associated with a diagnosis of peanut allergy.
Marcus Shaker, Joseph M. Chalil, Oth Tran, Anna Vlahiotis, Hemal Shah, Timothy King, Todd D. Green, Matthew Greenhawt> ;Annals of Allergy, Asthma & Immunology. 2020 Jan 16
84 citations
Conducting an Oral Food Challenge: An Update to the 2009 Adverse Reactions to Foods Committee Work Group Report
J. Andrew Bird, Stephanie A. Leonard, Marion Groetch, Amal Assa'ad, Antonella Cianferoni, April Clark, Maria Crain, Tracy Fausnight, David Fleischer, Todd D. Green, Ma...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2020 Jan 1
16 citations
Estimated risk reduction to packaged food reactions by epicutaneous immunotherapy (EPIT) for peanut allergy
Benjamin C. Remington, Tanja Krone, Edwin H. Kim, J. Andrew Bird, Todd D. Green, Gideon Lack, David Fleischer, Stef J. Koppelman> ;Annals of Allergy, Asthma & Immunology. 2019 Nov 1
144 citations
Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion among Children with Peanut Allergy: The PEPITES Randomized Clinical Trial
David Fleischer, Matthew Greenhawt, Gordon Sussman, Philippe Bégin, Anna Nowak-Wegrzyn, Daniel Petroni, Kirsten Beyer, Terri F. Brown-Whitehorn, Jacques Hébert, Jonath...> ;JAMA. 2019 Mar 12
143 citations
Effect of Varying Doses of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Exposure Among Patients With Peanut Sensitivity: A Randomized Clinical T...
Hugh A. Sampson, Wayne G. Shreffler, William H. Yang, Gordon Sussman, Terri F. Brown-Whitehorn, Kari C. Nadeau, Amarjit Cheema, Stephanie A. Leonard, Jacqueline A. Pon...> ;JAMA. 2017 Nov 14
39 citations
Multicenter prevalence of anaphylaxis in clinic-based oral food challenges.
Kwei Akuete, Danielle Guffey, Ryan B. Israelsen, John M. Broyles, Lori Jo Higgins, Todd D. Green, David R. Naimi, Andrew J. MacGinnitie, Girish Vitalpur, Charles G. Mi...> ;Annals of Allergy, Asthma & Immunology. 2017 Oct 1
54 citations
The emotional, social, and financial burden of food allergies on children and their families.
Nilamben Patel, Linda Herbert, Todd D. Green> ;Allergy and Asthma Proceedings. 2017 Mar 1
21 citations
Food allergy prevalence, knowledge, and behavioral trends among college students - A 6-year comparison.
Marilyn Karam, Rebecca Scherzer, Princess U. Ogbogu, Todd D. Green, Matthew Greenhawt> ;The Journal of Allergy and Clinical Immunology. in Practice. 2017 Mar 1
17 citations
Prevalence of food allergies in South Asia
Schweta R. Arakali, Todd D. Green, Chitra Dinakar> ;Annals of Allergy, Asthma & Immunology. 2017 Jan 1
20 citations
Deficits in allergy knowledge among physicians at academic medical centers
David R. Stukus, Todd D. Green, Shari V. Montandon, Kara J. Wada> ;Annals of Allergy, Asthma & Immunology. 2015 Jul 1
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Journal Articles

Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children with Peanut Allergy
Todd D Green, David M Fleischer, Hey Chong, R Sharon Chinthrajah, Edwin H Kim, Stacie M Jones, Robert Wood, Bruce J Lanser, Lynda Schneider, Jacqueline A Pongracic, Wa..., JAMA

Press Mentions

EPIT Significantly Improves Surveyed Peanut Allergy Quality of LifeNovember 9th, 2019
Patch Progress, Peanut OIT in Adults Data Presented at EAACI MeetingJune 7th, 2018
Hope Remains for the Viaskin Peanut PatchNovember 16th, 2017
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