TomasSalazarChanMD

Pediatrics • Bronx, NY

Physician

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Office
711 Nereid Ave
Bronx, NY 10466
Phone+1 718-994-6755

Fax+1 718-994-3032
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Summary

Dr. Tomas Chan, MD is a pediatrician in Bronx, New York. He is currently licensed to practice medicine in New York and New Jersey.

Education & Training

Wyckoff Heights Medical CenterResidency, Pediatrics, 1984 - 1987
St Louis University Sapientia Ae DificatClass of 1980

Certifications & Licensure

NY State Medical License 1987 - 2021
NJ State Medical License 1986 - 1991

Awards, Honors, & Recognition

Fellow (FAAP) American Academy of Pediatrics

Publications & Presentations

PubMed

Hepatocellular apoptosis in mice is associated with early upregulation of mitochondrial glucose metabolism.
Gottschalk, S., Zwingmann, C., Raymond, V. A., Hohnholt, M. C., Chan, T. S., Bilodeau, M.> ;Apoptosis. 2012 Feb
Organochlorines inhibit acetaminophen glucuronidation by redirecting UDP-glucuronic acid towards the D-glucuronate pathway.
Chan, T. S., Wilson, J. X., Selliah, S., Bilodeau, M., Zwingmann, C., Poon, R., O'Brien, P. J.> ;Toxicol Appl Pharmacol. 2008 Nov 1
Copper-catalyzed ascorbate oxidation results in glyoxal/AGE formation and cytotoxicity.
Shangari, N., Chan, T. S., Chan, K., Huai Wu, S., O'Brien, P. J.> ;Mol Nutr Food Res. 2007 Apr
Overprint immunoassay using protein A microarrays.
Matson, R. S., Milton, R. C., Rampal, J. B., Chan, T. S., Cress, M. C.> ;Methods Mol Biol. 2007
Printing low density protein arrays in microplates.
Matson, R. S., Milton, R. C., Cress, M. C., Chan, T. S., Rampal, J. B.> ;Methods Mol Biol. 2007
Herbal monoterpene alcohols inhibit propofol metabolism and prolong anesthesia time.
Li Lin, A., Shangari, N., Chan, T. S., Remirez, D., O'Brien, P. J.> ;Life Sci. 2006 May 30
Glyoxal markedly compromises hepatocyte resistance to hydrogen peroxide.
Shangari, N., Chan, T. S., Popovic, M., O'Brien, P. J.> ;Biochem Pharmacol. 2006 May 28
Coenzyme Q(1) depletes NAD(P)H and impairs recycling of ascorbate in astrocytes.
Dragan, M., Dixon, S. J., Jaworski, E., Chan, T. S., O'brien, P. J., Wilson, J. X.> ;Brain Res. 2006 Mar 17
The biosynthesis of ascorbate protects isolated rat hepatocytes from cumene hydroperoxide-mediated oxidative stress.
Chan, T. S., Shangari, N., Wilson, J. X., Chan, H., Butterworth, R. F., O'Brien, P. J.> ;Free Radic Biol Med. 2005 Apr 1
Sulfation and glucuronidation of phenols: implications in coenyzme Q metabolism.
Shangari, N., Chan, T. S., O'Brien, P. J.> ;Methods Enzymol. 2005
Application of quantitative structure-toxicity relationships for the comparison of the cytotoxicity of 14 p-benzoquinone congeners in primary cultured rat hepatocytes ...
Siraki, A. G., Chan, T. S., O'Brien, P. J.> ;Toxicol Sci. 2004 Sep
Glycogenolysis is directed towards ascorbate synthesis by glutathione conjugation.
Chan, T. S., Wilson, J. X., O'Brien, P. J.> ;Biochem Biophys Res Commun. 2004 Apr 23
Coenzyme Q cytoprotective mechanisms.
Chan, T. S., Wilson, J. X., O'Brien, P. J.> ;Methods Enzymol. 2004
Hepatocyte metabolism of coenzyme Q1 (ubiquinone-5) to its sulfate conjugate decreases its antioxidant activity.
Chan, T. S., O'Brien, P. J.> ;Biofactors. 2003
Effects of phosphodiesterase 3,4,5 inhibitors on hepatocyte cAMP levels, glycogenolysis, gluconeogenesis and susceptibility to a mitochondrial toxin.
Abdollahi, M., Chan, T. S., Subrahmanyam, V., O'Brien, P. J.> ;Mol Cell Biochem. 2003 Oct
Simultaneous detection of the antioxidant and pro-oxidant activity of dietary polyphenolics in a peroxidase system.
Chan, T. S., Galati, G., Pannala, A. S., Rice-Evans, C., O'Brien, P. J.> ;Free Radic Res. 2003 Jul
Idiosyncratic NSAID drug induced oxidative stress.
Galati, G., Tafazoli, S., Sabzevari, O., Chan, T. S., O'Brien, P. J.> ;Chem Biol Interact. 2002 Nov 10
N-oxidation of aromatic amines by intracellular oxidases.
Siraki, A. G., Chan, T. S., Galati, G., Teng, S., O'Brien, P. J.> ;Drug Metab Rev. 2002 Aug
Coenzyme Q cytoprotective mechanisms for mitochondrial complex I cytopathies involves NAD(P)H: quinone oxidoreductase 1(NQO1).
Chan, T. S., Teng, S., Wilson, J. X., Galati, G., Khan, S., O'Brien, P. J.> ;Free Radic Res. 2002 Apr
Endogenous and endobiotic induced reactive oxygen species formation by isolated hepatocytes.
Siraki, A. G., Pourahmad, J., Chan, T. S., Khan, S., O'Brien, P. J.> ;Free Radic Biol Med. 2002 Jan 1
Flavonoid B-ring chemistry and antioxidant activity: fast reaction kinetics.
Sekher Pannala, A., Chan, T. S., O'Brien, P. J., Rice-Evans, C. A.> ;Biochem Biophys Res Commun. 2001 Apr 20
Cancer chemoprevention and apoptosis mechanisms induced by dietary polyphenolics.
Galati, G., Teng, S., Moridani, M. Y., Chan, T. S., O'Brien, P. J.> ;Drug Metabol Drug Interact. 2000
Peroxidative metabolism of apigenin and naringenin versus luteolin and quercetin: glutathione oxidation and conjugation.
Galati, G., Moridani, M. Y., Chan, T. S., O'Brien, P. J.> ;Free Radic Biol Med. 2001 Feb 15
Hydrogen peroxide supports hepatocyte P450 catalysed xenobiotic/drug metabolic activation to form cytotoxic reactive intermediates.
Chan, T. S., Moridani, M., Siraki, A., Scobie, H., Beard, K., Eghbal, M. A., Galati, G., O'Brien, P. J.> ;Adv Exp Med Biol. 2001
Selective overproduction of human dihydrofolate reductase in a methotrexate-resistant human-mouse somatic cell hybrid.
Sastry, K. J., Chan, T. S., Rodriguez, L. V.> ;Biochem Biophys Res Commun. 1985 Oct 30
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Professional Memberships

American Academy of Pediatrics - AAP
Fellow