ToshiharuShin'OkaMDPhD

PubMed

• Tissue engineered vascular grafts are resistant to the formation of dystrophic calcification.
  Mackenzie E Turner, Kevin M Blum, Tatsuya Watanabe, Erica L Schwarz, Mahboubeh Nabavinia, Joseph T Leland, Delaney J Villarreal, William E Schwartzman, Ting-Heng Chou,...> ;Nature Communications. 2024 Mar 11
• Quantification of Skeletal Muscle Perfusion in Peripheral Artery Disease UsingF-Sodium Fluoride Positron Emission Tomography Imaging.
  Chou, T., Nabavinia, M., Tram, N., Rimmerman, E., Patel, S., Musini, K., Eisert, S., Wolfe, T., Wynveen, M., Matsuzaki, Y., Kitsuka, T., Iwaki, R., Janse, S., Bobbey, ...> ;Journal of the American Heart Association. 2024 Feb 20
• Evaluation of tissue-engineered human acellular vessels as a Blalock-Taussig-Thomas shunt in a juvenile primate model.
  Kevin M Nash, Brian A Boe, Sergio A Carrillo, Andrew Harrison, Ryuma Iwaki, John Kelly, Robert D Kirkton, Ramkumar Krishnamurthy, Jeffrey H Lawson, Yuichi Matsuzaki, H...> ;JTCVS Open. 2023 Sep 1
• 1 citations
  Patch Materials for Pulmonary Artery Arterioplasty and Right Ventricular Outflow Tract Augmentation: A Review.
  William E Schwartzman, Michael Jimenez, Andrew R Yates, Aimee K Armstrong, Arash Salavitabar, Kan K Hor, Simon Hoerstrup, Maximilian Y Emmert, Toshiharu Shinoka, Sergi...> ;Pediatric Cardiology. 2023 Jun 1
• 8 citations
  Recent Tissue Engineering Approaches to Mimicking the Extracellular Matrix Structure for Skin Regeneration.
  Rikako Hama, James W Reinhardt, Anudari Ulziibayar, Tatsuya Watanabe, John Kelly, Toshiharu Shinoka> ;Biomimetics. 2023 Mar 22
• 2 citations
  Tissue Engineering of Vascular Grafts: A Case Report From Bench to Bedside and Back.
  Thomas Breuer, Michael Jimenez, Jay D Humphrey, Toshiharu Shinoka, Christopher K Breuer> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2023 Mar 1
• The Application of Porous Scaffolds for Cardiovascular Tissues.
  Tatsuya Watanabe, Salha Sassi, Anudari Ulziibayar, Rikako Hama, Takahiro Kitsuka, Toshiharu Shinoka> ;Bioengineering. 2023 Feb 10
• 18 citations
  Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications.
  Rikako Hama, Anudari Ulziibayar, James W Reinhardt, Tatsuya Watanabe, John Kelly, Toshiharu Shinoka> ;Biomolecules. 2023 Feb 2
• 1 citations
  Computational analysis of serum-derived extracellular vesicle miRNAs in juvenile sheep model of single stage Fontan procedure.
  Hyun-Ji Park, John M Kelly, Jessica R Hoffman, Felipe Takaesu, William Schwartzman, Anudari Ulziibayar, Takahiro Kitsuka, Eric Heuer, Asigul Yimit, Raphael Malbrue, Co...> ;Extracellular Vesicle. 2022 Dec 1
• 1 citations
  Advances in Cardiac Tissue Engineering.
  Takahiro Kitsuka, Fuga Takahashi, James Reinhardt, Tatsuya Watanabe, Anudari Ulziibayar, Asigul Yimit, John Kelly, Toshiharu Shinoka> ;Bioengineering. 2022 Nov 16
• 10 citations
  Rapid Regeneration of a Neoartery with Elastic Lamellae.
  Ziyu Wang, Suzanne M Mithieux, Howard Vindin, Yiwei Wang, Miao Zhang, Linyang Liu, Jacob Zbinden, Kevin M Blum, Tai Yi, Yuichi Matsuzaki, Farshad Oveissi, Reyda Akdemi...> ;Advanced Materials. 2022 Nov 1
• 9 citations
  Clinical Application for Tissue Engineering Focused on Materials.
  Takahiro Kitsuka, Rikako Hama, Anudari Ulziibayar, Yuichi Matsuzaki, John Kelly, Toshiharu Shinoka> ;Biomedicines. 2022 Jun 17
• Pre-clinical Evolution of a Novel Transcatheter Bioabsorbable ASD/PFO Occluder Device.
  Yuichi Matsuzaki, Darren P Berman, Hirotsugu Kurobe, John M Kelly, Ryuma Iwaki, Kevin Blum, Shoji Toshihiro, Andrew Harrison, John P Cheatham, Toshiharu Shinoka> ;Pediatric Cardiology. 2022 Jun 1
• 13 citations
  Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth.
  Kevin M Blum, Jacob C Zbinden, Abhay B Ramachandra, Stephanie E Lindsey, Jason M Szafron, James W Reinhardt, Megan Heitkemper, Cameron A Best, Gabriel J M Mirhaidari, ...> ;Communications Medicine. 2022 Jan 1
• 4 citations
  Survival of Toddler with Aortoesophageal Fistula after Button Battery Ingestion.
  Hannah Gibbs, Rishabh Sethia, Patrick I. McConnell, Jennifer H. Aldrink, Toshiharu Shinoka, Kent C. Williams, Kris R. Jatana> ;Case Reports in Otolaryngology. 2021 Oct 5
• 4 citations
  Current status of developing tissue engineering vascular technologies
  Ryuma Iwaki, Toshihiro Shoji, Yuichi Matsuzaki, Anudari Ulziibayar, Toshiharu Shinoka> ;Expert Opinion on Biological Therapy. 2021 Aug 24
• 1 citations
  Publisher Correction: Hemodynamic performance of tissue-engineered vascular grafts in Fontan patients
  Erica L. Schwarz, John Kelly, Kevin M. Blum, Kan N. Hor, Andrew R. Yates, Jacob C. Zbinden, Aekaansh Verma, Stephanie E. Lindsey, Abhay B. Ramachandra, Jason M. Szafro...> ;NPJ Regenerative Medicine. 2021 Aug 12
• 23 citations
  Hemodynamic performance of tissue-engineered vascular grafts in Fontan patients
  Erica L. Schwarz, John Kelly, Kevin M. Blum, Kan N. Hor, Andrew R. Yates, Jacob C. Zbinden, Aekaansh Verma, Stephanie E. Lindsey, Abhay B. Ramachandra, Jason M. Szafro...> ;NPJ Regenerative Medicine. 2021 Jul 22
• 4 citations
  The Real Need for Regenerative Medicine in the Future of Congenital Heart Disease Treatment.
  Yuichi Matsuzaki, Matthew G Wiet, Brian A. Boe, Toshiharu Shinoka> ;Biomedicines. 2021 Apr 27
• 11 citations
  Improvement of a Novel Small-diameter Tissue-engineered Arterial Graft With Heparin Conjugation.
  Yuichi Matsuzaki, Shinka Miyamoto, Hideki Miyachi, Ryuma Iwaki, Toshihiro Shoji, Kevin M. Blum, Yu-Chun Chang, John Kelly, James W. Reinhardt, Hidetaka Nakayama, Chris...> ;The Annals of Thoracic Surgery. 2021 Apr 1
• 6 citations
  Evaluating the Longevity of the Fontan Pathway
  John Kelly, Gabriel J M Mirhaidari, Yu-Chun Chang, Toshiharu Shinoka, Christopher K. Breuer, Andrew R. Yates, Kan N. Hor> ;Pediatric Cardiology. 2020 Nov 8
• 10 citations
  Electrospun Tissue-Engineered Arterial Graft Thickness Affects Long-Term Composition and Mechanics
  Yen-Lin Wu, Jason M. Szafron, Kevin M. Blum, Jacob C. Zbinden, Ramak Khosravi, Cameron A. Best, James W. Reinhardt, Qiang Zeng, Tai Yi, Toshiharu Shinoka, Jay D. Humph...> ;Tissue Engineering. Part A. 2021 May 13
• 19 citations
  The Effect of Pore Diameter on Neo-tissue Formation in Electrospun Biodegradable Tissue-Engineered Arterial Grafts in a Large Animal Model
  Yuichi Matsuzaki, Ryuma Iwaki, James W. Reinhardt, Yu-Chun Chang, Shinka Miyamoto, John Kelly, Jacob C. Zbinden, Kevin M. Blum, Gabriel J M Mirhaidari, Anudari Ulziiba...> ;Acta Biomaterialia. 2020 Aug 18
• 2 citations
  The evaluation of a tissue-engineered cardiac patch seeded with hips derived cardiac progenitor cells in a rat left ventricular model.
  Yuichi Matsuzaki, Shinka Miyamoto, Hideki Miyachi, Tadahisa Sugiura, James W. Reinhardt, Chang Yu-Chun, Jacob C. Zbinden, Christopher K. Breuer, Toshiharu Shinoka> ;Plos One. 2020 Jun 8
• 12 citations
  3D printing with MRI in pediatric applications.
  Jayanthi Parthasarathy, Ramkumar Krishnamurthy, Adam P. Ostendorf, Toshiharu Shinoka, Rajesh Krishnamurthy> ;Journal of Magnetic Resonance Imaging. 2020 Jun 1
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Journal Articles

• Evaluation of remodeling process in small-diameter cell-free tissue –engineered arterial graft  
  Tara S, Kurobe H, Maxfield MW, Rocco KA, Yi T, Naito Y, Breuer CK, Shinoka T, J Vasc Surg, 1/15/2014
• Comparison of the biological equivalence of two methods for isolating bone marrow mononuclear cells for fabricating tissue-engineered vascular grafts  
  Tara S, Kurobe H, Maxfield MW, Rocco KA, Bagi P, Yi T, Udelsman B, Dean EW, Khosravi R, Powell HM, Shinoka T, Breuer CK, Tissue Eng Part C Methods, 1/14/2014
• Implantation of Inferior Vena Cava Interposition Graft in Mouse Model  
  Lee Y, Yi T, Tara S, Lee A, Hibino N, Shinoka T, Breuer C, Journal of Visualized Experiments, 1/4/2014
• Beyond Burst Pressure: Initial evaluation of the natural history of the biaxial mechanical properties of tissue engineered vascular grafts in the venous circulation us...  
  Naito Y, Lee YU, Yi T, Church SN, Solomon D, Humphrey JD, Shinoka T, Breuer CK, Tissue Engineering, 1/1/2014
• Targeted SPECT/CT Imaging of Matrix Metalloproteinase Activity in the Evaluation of Remodeling Tissue-Engineered Vascular Grafts Implanted in a Growing Lamb Model  
  Stacy MR, Naito Y, Maxfield MW, Kurobe H, Tara S, Chan C, Rocco KA, Shinoka T, Sinusas AJ, Breuer CK, JTCVS, 1/1/2014
• Comparison of a closed system to a standard open technique for preparing tissue engineered vascular graft  
  Kurobe H, Maxfield MW, Naito Y, Yi T, Shinoka T, Breuer CK, Tissue Engineering, 1/1/2014
• Development of a Tissue-Engineering Vascularf Gtraft for Use in Congenital Heart Surgery  
  Shinoka T, EBioMedicine, 1/1/2014
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  Tara S, Kurobe H, Maxfield MW, Rocco KA, Yi T, Naito Y, Breuer CK, Shinoka T, Atherosclerosis, 1/1/2014
• Vessel Bioengineering -Development of Small-Diameter Arterial Grafts-  
  Tara S, Rocco KA, Hibino N, Sugiura T, Kurobe H, Breuer CK, Shinoka T, Circulation Journal, 1/1/2014
• Seeding Tissue-Engineered Vascular Grafts in a Closed, Disposable Filter- Vacuum System  
  Breurer C, Shinoka T, Snyder E, BioProcess International, 1/1/2013
• Evaluation of small-diameter electrospun PCLA tissue engineered vascular grafts in a murine model: A case study highlighting the critical need for long-term implantati...  
  Rocco KA, Dean EW, Udelsman BV, Best C, Khosravi R, Maxfield MW, Yi T, Kurobe H, Tara S, Humphrey JD, Shinoka T, Breuer CK, Tissue Engineering Approaches in Regenerative Medicine, 1/1/2013
• Tissue Engineered Small-Diameter Arterial Graft: In Vivo Evaluation of an Electrospun Nanofiber Scaffold  
  K.A. Rocco, M.W. Maxfield, P.S. Bagi, H. Kurobe, T. Yi, T. Shinoka, C.K. Breuer, Journal of Surgical Research, 1/1/2013
• Evaluation of the Use of an iPS Cell Sheet for the Construction of Tissue Engineered Vascular Grafts  
  J Thorac Cardiovasc Surg, 1/1/2012
• Characterization of the natural history of extacellular matrix production in tissue engineered vascular grafts during neovessell formation  
  Naito Y, Williams-Fritze M, Madri J, Shinoka T, Breuer C, Cells, Tissue and Organs, 1/1/2012
• Modified Starnes procedure in a neonate with severe tricuspid regurgitation  
  Muralidaran A, Kim RW, Kopf GS, Pietris NP, Weeks BP, Boskovski MT, Starnes VA, Shinoka T, Annals of Thoracic Surg, 1/1/2012
• Development of an operator-independent method for seeding tissue-engineered vascular grafts  
  Udelsman B, Hibino N, Villalon GA, McGillicuddy E, Nieponice A, Sakamoto Y, Matsuda S, Vorp DA, Shinoka T, Breuer CK, Tissue Eng Part C Methods, 1/1/2011
• Determining the fate of seeded cells in venous tissue engineered vascular grafts using serial MRI  
  Harrington JK, Chahbourne H, Criscione JM, Li AY, Hibino N, Yi T, Villalona GA, Kobsa S, Meijas D, Duncan DR, Devine L, Papdemetris X, Shinoka T, Fahmy TM, Breuer CK, FASEB J, 1/1/2011
• A critical role for macrophages in neovessel formation and the development of stenosis in tissue engineered vascular grafts  
  Hibino N, Yi T, Duncan DR, Rathore A, Dean E, Naito Y, Dardik A, Kyriakides T, Madri J, Pober JS, Shinoka T, Breuer CK, FASEB J, 1/1/2011
• Vascular tissue engineering: towards the next generation vascular grafts  
  Naito Y, Shinoka T, Duncan D, Hibino N, Solomon D, Cleary M, Rathore A, Fein C, Church S, Breuer C, Adv Drug Deliv Rev, 1/1/2011
• Characterization of long-term cultured c-kitpos cardiac stem cells 9CSCs) derived from adult rat hearts  
  Miyamoto S, Kawaguchi N, Ellison GM, Matsuoka R, Shinoka T, Kurosawa H, Stem Cells and Development, 1/1/2010
• Late-term results of tissue-engineered vascular grafts in humans  
  Hibino N, McGillicuddy E, Matsumura G, Ichihara Y, Naito Y, Breuer C, Shinoka T, J Thorac Cardiovasc Surg, 1/1/2010
• Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling  
  Roh JD, Sawh-Martinez R, Brennan MP, Devine L, Jay SM, Yi T, Mirensky T, Udelsman B, Nelson GN, Hibino N, Shinoka T, Saltzman WM, Snyder E, Kyriakides TR, Pobert JS, B..., Proc Natl Acad Sci, 1/1/2010
• Tissue engineered vascular grafts: Does cell seeding matter?  
  Mirensky TL, Hibino N, Sawh-Martinez RF, Yi T, Villalona G, Shinoka T, Breuer CK, J Pediatr Surg, 1/1/2010
• Cell seeding techniques in vascular tissue engineering  
  Villalona GA, Udelsman B, Duncan DR, McGillicuddy E, Sawh-Martinez R, Mirensky T, Hibino N, Painter C, Erickson B, Shinoka T, Breuer C, Tissue Eng Part B Rev, 1/1/2010
• Tissue engineered pulmonary vascular graft in clinical setting  
  Hibino N, Shinoka T, Circulation Up-to-Date 4, 1/1/2009
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Books/Book Chapters

• Regenerative Medicine Application in Organ Transplantation 
  Chapter: Vessel Regeneration and Bioengineering 
  Page 811 - 829Tara S, Ethan W. Dean EW, Rocco KA, Udelsman BV, Kurobe H, Shinoka T Breuer CKEditors: Giuseppe Orlando, Jan P Lerut, Shay Soker, and Robert J Stratta.Elsevier Ltd, UK2013
• The Anatomical Record Advance in Integrative Anatomy and Evolutionary Biology 
  Chapter: Tissue Engineering in the Vasculature 
  Page 83 - 97Naito Y, Rocco K, Kurobe H, Maxfield M, Breuer C, Shinoka T2013
• Past, Present, and Future Stem Cells Translational Medicine 
  Chapter: Concise Review: Tissue-Engineered Vascular Grafts for Cardiac Suregery 
  Page 566 - 571Kurobe H, Maxfield MW, Breuer CK, Shinoka T2012
• Cardiac Regeneration and Repair: Volume 2 – Biomaterials and Tissue Engineering 
  Chapter: Stem Cells in Tissue Engineered Blood Vessels for Cardiac Repair 
  Kurobe H, Maxfield MW, Naito Y, Breuer CK, Shinoka TEditors: Li RK and Reisel R.Woodhead Publishing, Toronto, Canada2012
• Stem Cells in Tissue Engineering 
  Chapter: Cardiovascular system tissue engineered vascular grafts 
  Page 115 - 133Sawh-Martinez R, McGillicuddy E, Villanova GA, Shinoka T, Breuer CKEditors: Nicolas L’Heureux.2011
• Stem Cell Biology and Regenerative Medicine 
  Chapter: Restoring blood vessels 
  Hibino N, Breuer C, Shinoka TEditors: HS Bernstein.2011
• Hemodynamics & Mechanobiology of Endothelium 
  Chapter: Tissue engineered blood vessels: From the bench to the bedside and back again (Development of a vascular conduit for use in congenital heart surgery) 
  Page 271 - 290Salameh BS, Mirensky TL, Shinoka T, Breuer CKEditors: Tzung K Hsiai, Brett Blackman, and Hanjoong Jo.2010
• Principles of pulmonary protection during heart surgery 
  Chapter: Benefits of hemofiltration for lung function 
  Page 263 - 268Nagashima M, Shinoka TEditors: Edmo Atique Gabriel, M.D., Ph.D. and Tomas A. Salerno, M.D.2010
• In Regenerative Medicine 
  Chapter: Vascular Graft 
  Page 148 - 153Shinoka TEditors: Y Ikada.2007
• Tissue Engineering 
  Chapter: Vascular Tissue Engineering 
  Page 207 - 211Shinoka TEditors: Y Tabata, Igakukan.Tokyo, Japan2007
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Abstracts/Posters

• A Novel System for the Separation of Mononuclear Cells from Human Bone Marrow for the Creation of Tissue Engineered Vascular Grafts
  Shin'oka, T, International Society for Cellular Therapy, San Diego, CA, 1/1/2009
• Preliminary Evaluation of the Use of Embryonic Stem Cells for the Construction of Tissue Engineered Vascular Graft
  Shin'oka, T, Society of Thoracic Surgeons Meeting, San Francisco, CA, 1/1/2009
• Clinical Application of Tissue Engineering Vascular Graft
  Shin'oka, T, Tissue Engineering International and Regenerative Medicine Society Meeting, San Diego, CA, 1/10/2008
• The Role of Bone Marrow Mononuclear Cell Seeding for the Development of a Small Diameter Tissue Engineered Vascular Graft in SCID/bg Mouse Model
  Shin'oka, T, Tissue Engineering International and Regenerative Medicine Society Meeting, San Diego, CA, 1/1/2008
• Tissue Engineered Vascular Grafts Demonstrate Evidence of Growth and Development when Implanted in a Juvenile Animal Model
  Shin'oka, T, American Surgical Association Meeting, New York, NY, 1/1/2008
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Lectures

• Heart Valves: Basic Scientific Discoveries to Clinical Applications 
  Columbus, OH - 1/5/2014
• The development and translation of the tissue engineered vascular graft 
  Orlando, FL, 2010; Columbus, OH, 2014 - 1/4/2014
• Development of Tissue Engineered Vascular Graft for Pediatric Heart Surgery 
  Columbus, OH - 1/10/2013
• The Translation of the Tissue Engineered Vascular Graft 
  New Haven, CT - 1/22/2011
• Clinical Impact of Vascular Tissue Engineering in Pediatric Cardiovascular Surgery 
  1/13/2011
• The Development and Translation of Tissue Engineered Vascular Graft in Pediatric Cardiovascular Surgery 
  1/12/2011
• Clinical Results of Tissue Engineered Graft Implantation in Congenital Heart Surgery 
  Innsbruck, Austria - 1/28/2010
• Clinical Results of Tissue Engineered Venous Grafts in Pediatric Cardiac Surgery 
  Anaheim, CA - 1/27/2010
• Tissue Engineered Vascular Grafts: The Role of Autologus Bone Marrow Cell Seeding in Post-implantation Remodeling 
  Fort Lauderdale, FL - 1/26/2010
• Update on Tissue Engineering: What’s Growing? 
  Chicago, IL - 1/15/2010
• New Paradigms in Tissue Engineering 
  Galway, Ireland - 1/15/2010
• Clinical Impact of Vascular Tissue Engineering in Pediatric Surgery 
  Buenos Aires, Argentina - 1/14/2010
• Clinical Trial of Tissue Engineered Vascular Grafts in Patients with Congenital Cardiac Anomalies: An 8 year follow up 
  New Orleans, LA - 1/27/2009
• Clinical Application of Tissue Engineered Vascular Grafts in Pediatric Cardiac Surgery 
  1/22/2009
• The Use of Bone Marrow Cells in the Construction of Vascular Substitutes 
  Orlando, FL - 1/16/2009
• Eight Year Experience of Tissue-Engineered Vascular Autografts in Pediatric Cardiovascular Surgery 
  Bethesda, MD - 1/15/2009
• Clinical Application of Tissue Engineered Vascular Autografts in Pediatric Cardiac Surgery 
  1/7/2009
• Tissue Engineered Vascular Grafts in Humans: Correlating Clinical Outcomes to Vascular Neotissue Formation in Mice 
  Boston, MA - 1/1/2009
• Surgical Therapies for Complex Congenital Heart Disease 
  Norwalk, CT - 1/21/2008
• Development of Tissue Engineering Vascular Graft 
  Boston, MA - 1/10/2008
• Development of Tissue Engineered Vascular Autografts 
  1/1/2007
• Current Status of Tissue Engineered Vascular Autografts 
  1/1/2007
• Outcome of Definitive Surgical Repair for Congenitally Corrected Transposition of the Great Arteries or Atrioventricular Discordance with Double Outlet Right Ventricle 
  Beijing, China - 1/1/2006
• Tissue Engineering 
  1/1/2005
• Highlights of Successes in Regenerative Medicine 
  1/1/2005
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