WanpenVongpatanasinMD

Cardiology • Dallas, TX

Preventive Cardiology

Professor, Hypertension Section, Cardiology Division, University of Texas Southwestern Medical Center

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Office
5323 Harry Hines Boulevard
Dallas, TX 75390
Phone+1 214-645-8000

Fax+1 214-645-7277
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Education & Training

University of Texas Southwestern Medical CenterFellowship, Cardiovascular Disease, 1994 - 1998
University of Texas Southwestern Medical CenterResidency, Internal Medicine, 1991 - 1994
Chulalongkorn University Faculty of MedicineClass of 1991

Certifications & Licensure

TX State Medical License 1995 - 2025
PA State Medical License 1994 - 2000
American Board of Internal Medicine Cardiovascular Disease
American Society of HypertensionHypertension Specialist

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2012
Fellow (FACC) American College of Cardiology

Clinical Trials

Study to Improve Scientific Understanding of the Cardiovascular Actions of Cocaine
Withdrawn
Phase 1
Effects of Thiazide Diuretics on Sympathetic Nervous System in Hypertension Start of enrollment: 2005 Jan 01
Completed
Phase 4
Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients Start of enrollment: 2010 Aug 01
Completed
Phase 4
Comparison of Nebivolol and Metoprolol With Exercise and Angiotensin II in Hypertensive Patients Start of enrollment: 2009 Apr 01
Completed
Phase 4
Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension Start of enrollment: 2012 Oct 01
Completed
Phase 2
The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension Start of enrollment: 2013 Jul 01
Completed
Phase 2
Neural Mechanism of Aldosterone-induced Insulin Resistance Start of enrollment: 2010 Nov 01
Withdrawn
Phase 4
Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension Start of enrollment: 2012 Sep 01
Completed
Phase 4
Mechanisms of Muscle Blood Flow Dysregulation and Exercise Intolerance in Chronic Kidney Disease Start of enrollment: 2016 Jan 01
Terminated
Not Applicable
Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrate Start of enrollment: 2015 Jan 01
Completed
Not Applicable
Hypertension, Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial) Start of enrollment: 2018 Apr 10
Active, not recruiting
Phase 2
Therapeutic Drug Monitoring of Cardiac Medications Start of enrollment: 2018 Aug 01
Terminated
Preventing Hypertension and Sympathetic Overactivation by Targeting Phosphate Start of enrollment: 2017 Oct 16
Completed
Phase 2
Roles: Contact, Principal Investigator
Preventing Cognitive Decline by Reducing BP Target Trial Start of enrollment: 2022 Jul 11
Recruiting
Not Applicable
Roles: Contact
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Publications & Presentations

PubMed

HDL-C and apolipoprotein A-I are independently associated with skeletal muscle mitochondrial function in healthy humans.
John M Giacona, Ursa B Petric, Weerapat Kositanurit, Jijia Wang, Suzanne Saldanha, Benjamin E Young, Ghazi Khan, Margery A Connelly, Scott A Smith, Anand Rohatgi, Wanp...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2024 Apr 1
Severe Hypertension in Hospitalized Patients: To Treat or Not to Treat?
Giacona, J. M., Giacona, J. M., Giacona, J. M., Giacona, J. M., Wanpen Vongpatanasin, John M Giacona> ;American Journal of Hypertension. 2024 Mar 15
Association between Dietary Phosphate Intake on Skeletal Muscle Mitochondrial Function in Adults without Cardiovascular Disease.
John M Giacona, Areeb Afridi, Ursa Bezan Petric, Talon Johnson, Johanne Pastor, Jimin Ren, Lona Sandon, Craig Malloy, Ambarish Pandey, Amil Shah, Jarett D Berry, Orson...> ;Journal of Applied Physiology. 2024 Mar 14
The Next Chapter of Renal Denervation After US Food and Drug Administration Approval.
Wanpen Vongpatanasin, Tayo Addo> ;Circulation. 2024 Mar 5
Preventing cognitive decline by reducing BP target (PCOT): A randomized, pragmatic, multi-health systems clinical trial.
Giacona, J. M., Giacona, J. M., Giacona, J. M., Giacona, J. M., John M Giacona, Brooke M Bates, Venkatraghavan Sundaram, Stephanie Brinker, Elizabeth Moss, Raja Paspul...> ;Contemporary Clinical Trials. 2024 Mar 1
Management of Resistant Hypertension-An Update.
John M Giacona, Weerapat Kositanurit, Wanpen Vongpatanasin> ;JAMA Internal Medicine. 2024 Apr 1
Tirzepatide Reduces 24-Hour Ambulatory Blood Pressure in Adults With Body Mass Index ≥27 kg/m: SURMOUNT-1 Ambulatory Blood Pressure Monitoring Substudy.
James A de Lemos, Bruno Linetzky, Carel W le Roux, Luke J Laffin, Wanpen Vongpatanasin, Ludi Fan, Andrea Hemmingway, Nadia N Ahmad, Mathijs C Bunck, Adam Stefanski> ;Hypertension. 2024 Apr 1
Potassium Magnesium Citrate Is Superior to Potassium Chloride in Reversing Metabolic Side Effects of Chlorthalidone.
Wanpen Vongpatanasin, John M Giacona, Danielle Pittman, Ashley Murillo, Ghazi Khan, Jijia Wang, Talon Johnson, Jimin Ren, Orson W Moe, Charles C Y Pak> ;Hypertension. 2023 Dec 1
Recruitment methods and yield rates for a multisite clinical trial exploring risk reduction for Alzheimer's disease (rrAD).
Amanda N Szabo-Reed, Tristyn Hall, Eric D Vidoni, Angela Van Sciver, Monica Sewell, Jeffrey M Burns, C Munro Cullum, William P Gahan, Linda S Hynan, Diana R Kerwin, He...> ;Alzheimer's & Dementia. 2023 Oct 14
Utility of standing office blood pressure in detecting hypertension in healthy adults.
John M Giacona, Weerapat Kositanurit, Jijia Wang, Ursa B Petric, Ghazi Khan, Danielle Pittman, Jon W Williamson, Scott A Smith, Wanpen Vongpatanasin> ;Scientific Reports. 2023 Sep 20
3 citations
Diagnostic performance of the adrenal vein to inferior vena cava aldosterone ratio in classifying the subtype of primary aldosteronism.
Kyle J O'Malley, Mhd W Alnablsi, Yin Xi, Mona Pathak, Fatima Khan, Anil K Pillai, Manoj K Kathuria, Wanpen Vongpatanasin> ;Hypertension Research. 2023 Nov 1
1 citations
Blockade of endogenous insulin receptor signaling in the nucleus tractus solitarius potentiates exercise pressor reflex function in healthy male rats.
Juan A Estrada, Norio Hotta, Han-Kyul Kim, Rie Ishizawa, Ayumi Fukazawa, Gary A Iwamoto, Scott A Smith, Wanpen Vongpatanasin, Masaki Mizuno> ;FASEB Journal. 2023 Sep 1
Trends in Ambulatory Blood Pressure Monitoring in Five High-Volume Medical Centers.
Stephen P Juraschek, Natalie A Bello, Alexander R Chang, Jennifer L Cluett, Karen A Griffin, Alan Hinderliter, Kenneth J Mukamal, Ruth-Alma N Turkson-Ocran, Raven Voor...> ;Hypertension. 2023 Aug 1
1 citations
Neural discharge of muscle afferents and pressor response to mechanical stimulation are associated with muscle deformation velocity in rats.
Rie Ishizawa, Juan A Estrada, Han-Kyul Kim, Norio Hotta, Ayumi Fukazawa, Gary A Iwamoto, Scott A Smith, Wanpen Vongpatanasin, Masaki Mizuno> ;American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 2023 Jul 1
Greater resting muscle sympathetic nerve activity reduces cold pressor autonomic reactivity in older women, but not older men.
John D Akins, Joseph M Hendrix, Wanpen Vongpatanasin, Qi Fu, Okada, Y.> ;American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 2023 Mar 27
2 citations
Antagonism of TRPV4 channels partially reduces mechanotransduction in rat skeletal muscle afferents.
Ayumi Fukazawa, Amane Hori, Norio Hotta, Kimiaki Katanosaka, Juan A Estrada, Rie Ishizawa, Han-Kyul Kim, Gary A Iwamoto, Scott A Smith, Wanpen Vongpatanasin, Masaki Mi...> ;The Journal of Physiology. 2023 Apr 1
Eggs and the heart.
Franz H Messerli, Wanpen Vongpatanasin, Adrian W Messerli> ;European Heart Journal. 2022 Dec 1
Comparison of Pharmacy Refill Data With Chemical Adherence Testing in Assessing Medication Nonadherence in a Safety Net Hospital Setting.
David Osula, Kevin Schesing, Sandeep R Das, Elizabeth Moss, Kristin Alvarez, Christopher Clark, Ethan A Halm, Nancy J Brown, Wanpen Vongpatanasin, Wu, B.> ;Journal of the American Heart Association. 2022 Oct 4
4 citations
Renal denervation in the antihypertensive arsenal - knowns and known unknowns.
Franz H Messerli, Chirag Bavishi, Jana Brguljan, Michel Burnier, Stephan Dobner, Fernando Elijovich, Keith C Ferdinand, Sverre Kjeldsen, Cheryl L Laffer, C Venkata S R...> ;Journal of Hypertension. 2022 Oct 1
MEN2B Masquerading as Postural Orthostatic Tachycardia Syndrome.
Ghazi Khan, John Giacona, Sasan Mirfakhraee, Steven Vernino, Wanpen Vongpatanasin> ;JACC. Case Reports. 2022 Jul 6
7 citations
Dapagliflozin Attenuates Sympathetic and Pressor Responses to Stress in Young Prehypertensive Spontaneously Hypertensive Rats.
Han-Kyul Kim, Rie Ishizawa, Ayumi Fukazawa, Zhongyun Wang, Ursa Bezan Petric, Ming Chang Hu, Scott A Smith, Masaki Mizuno, Wanpen Vongpatanasin> ;Hypertension. 2022 Aug 1
3 citations
Soluble Fms-like tyrosine kinase-1 (sFlt-1) is associated with subclinical and clinical atherosclerotic cardiovascular disease: The Dallas Heart Study.
Rina Mauricio, Kavisha Singh, Monika Sanghavi, Colby R Ayers, Anand Rohatgi, Wanpen Vongpatanasin, James A de Lemos, Amit Khera> ;Atherosclerosis. 2022 Apr 1
7 citations
Insulin potentiates the response to capsaicin in dorsal root ganglion neurons in vitro and muscle afferents ex vivo in normal healthy rodents.
Amane Hori, Norio Hotta, Ayumi Fukazawa, Juan A Estrada, Kimiaki Katanosaka, Kazue Mizumura, Jun Sato, Rie Ishizawa, Han-Kyul Kim, Gary A Iwamoto, Wanpen Vongpatanasin...> ;The Journal of Physiology. 2022 Feb 1
4 citations
Evaluation of noise regression techniques in resting-state fMRI studies using data of 434 older adults.
Norman Scheel, Jeffrey N Keller, Ellen F Binder, Eric D Vidoni, Jeffrey M Burns, Binu P Thomas, Ann M Stowe, Linda S Hynan, Diana R Kerwin, Wanpen Vongpatanasin, Heidi...> ;Frontiers in Neuroscience. 2022 Jan 1
1 citations
Renal Nerve Activity and Arterial Depressor Responses Induced by Neuromodulation of the Deep Peroneal Nerve in Spontaneously Hypertensive Rats.
Maria Alejandra Gonzalez-Gonzalez, Kevin Romero, John Beitter, David Lloyd, Danny V Lam, Ana Guadalupe Hernandez-Reynoso, Aswini Kanneganti, Han-Kyul Kim, Caroline K B...> ;Frontiers in Neuroscience. 2022 Jan 1
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Journal Articles

Association of Genetic West African Ancestry, Blood Pressure Response to Therapy, and Cardiovascular Risk Among Self-Reported Black Individuals in the Systolic Blood P...
Wanpen Vongpatanasin, MD, JAMA Cardiology

Press Mentions

Should Patients Stand for Office BP Readings?September 15th, 2022
How to Spot the Signs of High Blood PressureJune 17th, 2022
He Spent His Entire Professional Career at the University of Texas Southwestern Medical School in Dallas—Except for 1 Year at the National Institutes of HealthSeptember 25th, 2020
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Grant Support

The Role of Aldosterone on Exercise Pressor Reflex in HypertensionNational Heart, Lung, and Blood Institute (NHLBI)2013–Present
Neural Mechanism Of Thiazide-Induced Insulin ResistanceNational Heart, Lung, And Blood Institute2005–2008
Postmenopausal Hormonal Replacement TherapyNational Center For Research Resources2002–2006