WendyBethBernsteinMD

Oncology • Bethesda, MD

Hematologic Oncology

Associate Professor, Medicine, Uniformed Services Hebert SOM

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Office
Hamb/Nci/Nih/Cc 10 Center Drive
Building10 Rm 10s255 Msc 1868
Bethesda, MD 20892
Phone+1 301-435-9281

Fax+1 301-402-7552
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Education & Training

National Capital ConsortiumFellowship, Hematology and Medical Oncology, 1984 - 1987
National Capital ConsortiumResidency, Internal Medicine, 1981 - 1984
UniforMed Services University of the Health Sciences F. Edward Hebert School of MedicineClass of 1981

Certifications & Licensure

PA State Medical License 1987 - 2024
MD State Medical License 2017 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Hematology
American Board of Internal Medicine Medical Oncology

Publications & Presentations

PubMed

74 citations
Effect of Aspirin on Cancer Incidence and Mortality in Older Adults.
John J McNeil, Peter Gibbs, Suzanne G Orchard, Jessica E. Lockery, Wendy B. Bernstein, Yin Cao, Leslie G. Ford, Andrew Haydon, Brenda Kirpach, Finlay A. Macrae, Catrio...> ;Journal of the National Cancer Institute. 2021 Mar 1
13 citations
A phase I/II study of pemetrexed with sirolimus in advanced, previously treated non-small cell lung cancer.
Takefumi Komiya, Regan M. Memmott, Gideon M. Blumenthal, Wendy B. Bernstein, Marc S. Ballas, Roopa De Chowdhury, Guinevere Chun, Cody J. Peer, William D. Figg, David J...> ;Translational Lung Cancer Research. 2019 May 13
18 citations
A Phase Ib Study of Sorafenib (BAY 43‐9006) in Patients with Kaposi Sarcoma
Thomas S. Uldrick, Priscila H. Goncalves, Kathleen M. Wyvill, Cody J. Peer, Wendy B. Bernstein, Karen Aleman, Mark N. Polizzotto, David Venzon, Seth M. Steinberg, Vick...> ;The Oncologist. 2017 May 1
29 citations
A phase I trial of the HIV protease inhibitor nelfinavir in adults with solid tumors
Gideon M. Blumenthal, Joell J. Gills, Marc S. Ballas, Wendy B. Bernstein, Takefumi Komiya, Roopa DeChowdhury, Betsy Morrow, Hyejeong Root, Guinevere Chun, Cynthia Hels...> ;Oncotarget. 2014 Sep 8
468 citations
Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells
John Scholler, Troy Brady, Gwendolyn Binder-Scholl, Wei-Ting Hwang, Gabriela Plesa, Kristen Hege, Ashley N. Vogel, Michael Kalos, James L. Riley, Steven G. Deeks, Rona...> ;Science Translational Medicine. 2012 May 2
74 citations
Phase II Study of Bevacizumab in Patients With HIV-Associated Kaposi's Sarcoma Receiving Antiretroviral Therapy
Thomas S. Uldrick, Kathleen M. Wyvill, Pallavi Kumar, Deirdre O'Mahony, Wendy B. Bernstein, Karen Aleman, Mark N. Polizzotto, Seth M. Steinberg, Stefania Pittaluga, Vi...> ;Journal of Clinical Oncology. 2012 May 1
67 citations
A Randomized Controlled Trial of Local Heat Therapy Versus Intravenous Sodium Stibogluconate for the Treatment of Cutaneous Leishmania major Infection
Naomi E. Aronson, Glenn Wortmann, William R. Byrne, Robin S. Howard, Wendy B. Bernstein, Mary A. Marovich, Mark E. Polhemus, In-Kyu Yoon, Kelly A. Hummer, Robert A. Ga...> ;Plos Neglected Tropical Diseases. 2010 Mar 9
A phase I study of nelfinavir, an FDA approved HIV protease inhibitor, in adults with refractory solid tumors.
Dennis PA, Blumenthal G, Ballas M, Gardner E, Kawabata S, LoPiccolo J, Helsabeck C, Root H, Figg WD, Bernstein W> ;J. Clin. Oncol.. 2009-05-20
60 citations
Repositioning HIV protease inhibitors as cancer therapeutics.
Wendy B. Bernstein, Phillip A. Dennis> ;Current Opinion in HIV and AIDS. 2008 Nov 1
20 citations
Diagnosing leptomeningeal carcinomatosis with negative CSF cytology in advanced prostate cancer.
Wendy B. Bernstein, Jean D. Kemp, Geoffrey S. Kim, Viviana V. Johnson> ;Journal of Clinical Oncology. 2008 Jul 1
Preliminary results of a clinical trial using chemo-immunotherapy in Kaposi sarcoma herpesvirus (KSHV)-associated multicentric Castleman's disease (MCD).
O'Mahony D, Aleman K, Bernstein WB, Wyvill K, Whitby D, Tosato G, Jaffe ES, Pittaluga S, Little RF, Yarchoan R> ;J. Clin. Oncol.. 2008-05-20
602 citations
Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations
Jaclyn LoPiccolo, Gideon M. Blumenthal, Wendy B. Bernstein, Phillip A. Dennis> ;Drug Resistance Updates. 2008 Feb 1
26 citations
Acquired immunodeficiency syndrome—related malignancies in the era of highly active antiretroviral therapy
Wendy B. Bernstein, Richard F. Little, Wyndham H. Wilson> ;International Journal of Hematology. 2006 Jul 1
43 citations
Functional Genomic Relationships in HIV-1 Disease Revealed by Gene-Expression Profiling of Primary Human Peripheral Blood Mononuclear Cells
Christian F. Ockenhouse, Wendy B. Bernstein, Zhining Wang, Maryanne Vahey> ;The Journal of Infectious Diseases. 2005 Jun 15
383 citations
Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion.
Jonathan P. Pearl, Jeremy Parris, Douglas A. Hale, Steven C. Hoffmann, Wendy B. Bernstein, Kelly L. McCoy, S. John Swanson, Roslyn B. Mannon, Mario Roederer, Allan D. ...> ;American Journal of Transplantation. 2005 Mar 1
22 citations
Immune reconstitution following autologous transfers of CD3/CD28 stimulated CD4(+) T cells to HIV-infected persons.
Wendy B. Bernstein, Josephine H. Cox, Naomi E. Aronson, LaRee Tracy, Katia Schlienger, Silvia Ratto-Kim, Robin P. Garner, Julio Cotte, Zhaohui Zheng, Lena E. Winestone...> ;Clinical Immunology. 2004 Jun 1
134 citations
Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene t...
Linda M. Muul, Laura M. Tuschong, Sherry L. Soenen, G. Jayashree Jagadeesh, W. Jay Ramsey, Zhifeng Long, Charles S. Carter, Elizabeth Garabedian, Melinna Alleyne, Marg...> ;Blood. 2003 Apr 1
119 citations
Mechanisms for Linezolid-Induced Anemia and Thrombocytopenia
Wendy B. Bernstein, Richard F. Trotta, James T Rector, Jeffery A Tjaden, Anthony J Barile> ;The Annals of Pharmacotherapy. 2003 Apr 1
25 citations
Preparation of Clinical-Grade Recombinant Canarypox–Human Immunodeficiency Virus Vaccine–Loaded Human Dendritic Cells
Mary A. Marovich, John R. Mascola, Michael A. Eller, Mark K. Louder, Pierre A. Caudrelier, Raphaelle El-Habib, Silvia Ratto-Kim, Josephine H. Cox, Jeffrey R. Currier, ...> ;The Journal of Infectious Diseases. 2002 Nov 1
34 citations
Comprehensive screening for human immunodeficiency virus type 1 subtype-specific CD8 cytotoxic T lymphocytes and definition of degenerate epitopes restricted by HLA-A0...
Jeffrey R. Currier, Mark S. deSouza, Penprapa Chanbancherd, Wendy B. Bernstein, Deborah L. Birx, Josephine H. Cox> ;Journal of Virology. 2002 May 15
142 citations
Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection.
Bruce L. Levine, Wendy B. Bernstein, Naomi E. Aronson, Katia Schlienger, Julio Cotte, Steven J. Perfetto, Mary J. Humphries, Silvia Ratto-Kim, Deborah L. Birx, Carolyn...> ;Nature Medicine. 2002 Jan 1
96 citations
Large-Scale Production of CD4+ T Cells from HIV-1-Infected Donors After CD3/CD28 Costimulation*
Bruce L. Levine, Julio Cotte, Carolynn C. Small, Richard G. Carroll, James L. Riley, Wendy B. Bernstein, Dennis E. Van Epps, R. Alan Hardwick, Carl H. June> ;Journal of Hematotherapy. 1998 Oct 1
282 citations
Effects of CD28 costimulation on long-term proliferation of CD4+ T cells in the absence of exogenous feeder cells.
Bruce L. Levine, Wendy B. Bernstein, Mark Connors, Nancy Craighead, Tullia Lindsten, Craig B. Thompson, Carl H. June> ;Journal of Immunology. 1997 Dec 15
4 citations
Ex vivo replicative potential of adult human peripheral blood CD4+ T cells.
Bruce L. Levine, Wendy B. Bernstein, Nancy Craighead, Craig B. Thompson, Tullia Lindsten, D C St Louis, Carl H. June> ;Transplantation Proceedings. 1997 Jun 1
60 citations
Intrinsic resistance to T cell infection with HIV type 1 induced by CD28 costimulation.
James L. Riley, Richard G. Carroll, Bruce L. Levine, Wendy B. Bernstein, D C St Louis, Owen S. Weislow, Carl H. June> ;Journal of Immunology. 1997 Jun 1
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