William Cheshire Jr., MD

William Cheshire Jr., MD, MA

Neurology Jacksonville, FL

Professor of Neurology Mayo Clinic

Office Address

Office Map
  • 4500 San Pablo Rd S
    Jacksonville, FL 32224
    Phone: (904) 953-2000


  • I work with a world-class team of colleagues at Mayo Clinic who are dedicated to caring for patients and advancing medical science. My clinical practice is tertiary, outpatient, and highly collaborative, focusing on the diagnosis and evaluation of disorders of the autonomic nervous system. I am passionate about discovery, whether that be finding solutions for patients with complex problems, new insights in neuroscience, or connections between neuroscience and complementary disciplines that illuminate our understanding what it means to be human.

Dr. Cheshire's Clinical Specialties & Interests

  • Neurology: General Neurology
  • Clinical Interests: Autonomic Nervous System Diseases; Neuroethics; Trigeminal Neuralgia; Ethics of Emerging Technologies

Dr. Cheshire's Faculty Appointments & Work History

  • ProfessorMayo Clinic
  • DirectorMayo Clinic in Florida
  • Associate DirectorMayo Clinic
  • President of the StaffMayo Clinic in Florida
    Jacksonville, FL

Dr. Cheshire's Education & Medical Training

  • Trinity International UniversityTrinity International UniversityOther Training, MA, Bioethics, Summa cum laude
  • University of North Carolina HospitalsUniversity of North Carolina HospitalsFellowship, Pain Medicine
  • University of North Carolina HospitalsUniversity of North Carolina HospitalsResidency, Neurology
  • West Virginia UniversityWest Virginia UniversityInternship, Internal Medicine
  • WV Univ Sch of MedWest Virginia University School of MedicineMedical School
  • Princeton UniversityPrinceton UniversityOther Training, AB, Biochemistry, Cum laude

Dr. Cheshire's Certifications & Licensure

  • FL State Medical LicenseFL State Medical License1992 - 2016
  • MN State Medical LicenseMN State Medical License1992 - 2014
  • NC State Medical LicenseNC State Medical License1991 - 2014
  • American Board of Psychiatry and NeurologyAmerican Board of Psychiatry and NeurologyNeurology, 1994

Dr. Cheshire's Awards, Honors, & Recognition

  • best doctorsmemberbest doctors, 2012
  • American Neurological AssociationMemberAmerican Neurological Association, 2007
  • University of Oklahoma School of MedicineA. Kurt Weiss Lecturer in Biomedical EthicsUniversity of Oklahoma School of Medicine, 2005
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Dr. Cheshire's Publications & Presentations

PubMed | Citations by Web of Science®

Grant Support

  • Double-Blind, Placebo-Controlled Study of Rifampicin in Multiple System Atrophy
    Double-Blind, Placebo-Controlled Study of Rifampicin in Multiple System AtrophyNational Institutes of Health
    2011 - 2013


  • Autonomic Disorders Examination Committee, UCNSMember2008 - 2012
  • Autonomic Disorders Section, American Academy of NeurologyChair2002 - 2004
  • Board of Directors, American Autonomic SocietyMember2013 - Present
  • Ethics Committee, Christian Medical and Dental AssociationsChair2011 - Present
  • Grievance Committee, American Academy of NeurologyMember2009 - Present
  • Editorial Board, Autonomic NeuroscienceMember2010 - Present

Hospital Affiliations

Insurance Accepted

  • Aetna Choice POS II
  • BCBS Blue Card PPO
  • BCBS Florida NetworkBlue
  • BCBS Florida Preferred Patient Care PPO
  • CIGNA Open Access
  • First Health PPO
  • Great West PPO
  • Multiplan PHCS PPO
  • Multiplan PPO
  • United Healthcare - Direct Choice Plus POS
  • United Healthcare - Direct Options PPO

Medical Groups

  • Mayo Clinic

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