WilliamBrianDaltonMDPhD

PubMed

• 1 citations
  Co-occurring mutations in ASXL1, SRSF2, and SETBP1 define a subset of myelodysplastic/ myeloproliferative neoplasm with neutrophilia.
  Tania Jain, Alisha D Ware, William Brian Dalton, Sergiu Pasca, Hua-Ling Tsai, Christopher D Gocke, Lukasz P Gondek, Rena R Xian, Michael J Borowitz, Mark J Levis> ;Leukemia Research. 2023 Aug 1
• 3 citations
  Venetoclax in combination with hypomethylating agent for the treatment of advanced myeloproliferative neoplasms and acute myeloid leukemia with extramedullary disease.
  Khaled Sanber, Kevin Ye, Hua-Ling Tsai, Matthew Newman, Jonathan A Webster, Ivana Gojo, Gabriel Ghiaur, Gabrielle T Prince, Lukasz P Gondek, B Douglas Smith, Mark J Le...> ;Leukemia & Lymphoma. 2023 Apr 1
• 2 citations
  CCRL2 affects the sensitivity of myelodysplastic syndrome and secondary acute myeloid leukemia cells to azacitidine.
  Theodoros Karantanos, Patric Teodorescu, Marios Arvanitis, Brandy Perkins, Tania Jain, Amy E DeZern, W Brian Dalton, Ilias Christodoulou, Bogdan C Paun, Ravi Varadhan,...> ;Haematologica. 2023 Jul 1
• 8 citations
  Genomic landscape of myelodysplastic/myeloproliferative neoplasm can predict response to hypomethylating agent therapy.
  Theodoros Karantanos, Hua-Ling Tsai, Lukasz P Gondek, Amy E DeZern, Gabriel Ghiaur, W Brian Dalton, Ivana Gojo, Gabrielle T Prince, Jonathan Webster, Alexander Ambinde...> ;Leukemia & Lymphoma. 2022 Aug 1
• 11 citations
  Post-Transplantation Cyclophosphamide-Based Graft- versus-Host Disease Prophylaxis with Nonmyeloablative Conditioning for Blood or Marrow Transplantation for Myelofibr...
  Tania Jain, Hua-Ling Tsai, Amy E DeZern, Lukasz P Gondek, Hany Elmariah, Javier Bolaños-Meade, Leonido Luznik, Ephraim Fuchs, Richard Ambinder, Douglas E Gladstone, Ph...> ;Transplantation and Cellular Therapy. 2022 May 1
• 6 citations
  Taking the STING out of acute myeloid leukemia through macrophage-mediated phagocytosis.
  William Brian Dalton, Gabriel Ghiaur, Linda Ms Resar> ;The Journal of Clinical Investigation. 2022 Mar 1
• 8 citations
  The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia.
  Theodoros Karantanos, Patric Teodorescu, Ilias Christodoulou, Christopher Esteb, Ravi Varadhan, Eric Helmenstine, Trivikram Rajkhowa, Bogdan C Paun, Challice Bonifant,...> ;Science Advances. 2022 Feb 18
• 1 citations
  PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model.
  Karen Cravero, Morgan V Pantone, Dong Ho Shin, Riley Bergman, Rory Cochran, David Chu, Daniel J Zabransky, Swathi Karthikeyan, Ian G Waters, Natasha Hunter, D Marc Ros...> ;Oncotarget. 2022 Jan 1
• 5 citations
  How low risk are low risk myelodysplastic syndromes?
  Amy E DeZern, William Brian Dalton> ;Expert Review of Hematology. 2022 Jan 1
• 4 citations
  Nonmyeloablative Allogeneic Transplantation With Post-Transplant Cyclophosphamide for Acute Myeloid Leukemia With IDH Mutations: A Single Center Experience.
  Alexander J. Ambinder, Matthew D. Smith, Hua-Ling Tsai, Ravi Varadhan, Amy E. DeZern, William Dalton, Christian B. Gocke, Jonathan Webster, Lukasz P. Gondek, Ivana Goj...> ;Clinical Lymphoma, Myeloma & Leukemia. 2021 Oct 9
• 18 citations
  G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis.
  Annemarie Boleij, Payam Fathi, William Brian Dalton, Ben Park, Xinqun Wu, David L. Huso, Jawara Allen, Sepideh Besharati, Robert A. Anders, Franck Housseau, Amanda E. ...> ;Communications Biology. 2021 May 14
• 21 citations
  Allogeneic transplantation for Ph+ acute lymphoblastic leukemia with posttransplantation cyclophosphamide.
  Jonathan Webster, Leo Luznik, Hua Ling Tsai, Philip H. Imus, Amy E. DeZern, Keith W. Pratz, Mark Levis, Ivana Gojo, Margaret M. Showel, Gabrielle T. Prince, Javier Bol...> ;Blood Advances. 2020 Oct 27
• 2 citations
  Parkin on serine: a Parkinson disease gene suppresses serine synthesis in cancer
  W. Brian Dalton> ;The Journal of Clinical Investigation. 2020 Jun 1
• 32 citations
  The K666N mutation in SF3B1 is associated with increased progression of MDS and distinct RNA splicing.
  W. Brian Dalton, Eric Helmenstine, Lisa Pieterse, Bing Li, Christopher D. Gocke, Joshua Donaldson, Zhijian Xiao, Lukasz P. Gondek, Gabriel Ghiaur, Ivana Gojo, B. Dougl...> ;Blood Advances. 2020 Apr 14
• 4 citations
  The metabolic reprogramming and vulnerability of SF3B1 mutations.
  W. Brian Dalton> ;Molecular & Cellular Oncology. 2020 Feb 16
• 37 citations
  Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation
  W. Brian Dalton, Eric Helmenstine, Noel Walsh, Lukasz P. Gondek, Dhanashree S. Kelkar, Abigail Read, Rachael Natrajan, Eric S. Christenson, Barbara Roman, Samarjit Das...> ;The Journal of Clinical Investigation. 2019 Nov 1
• 8 citations
  Fibrinogen consumption and use of heparin are risk factors for delayed bleeding during acute promyelocytic leukemia induction.
  Bryan C. Hambley, Kelly J. Norsworthy, Jagar Jasem, Jacquelyn W. Zimmerman, Eugene Shenderov, Jonathan Webster, Margaret M. Showel, Lukasz P. Gondek, William Brian Dal...> ;Leukemia Research. 2019 Jun 21
• 2 citations
  The estrogen receptor-alpha S118P variant does not affect breast cancer incidence or response to endocrine therapies
  Berry Button, Sarah Croessmann, David Chu, D. Marc Rosen, Daniel J. Zabransky, W. Brian Dalton, Karen Cravero, Kelly Kyker-Snowman, Ian Waters, Swathi Karthikeyan, Eri...> ;Breast Cancer Research and Treatment. 2019 Apr 15
• 6 citations
  Single-Nucleotide Polymorphism Leading to False Allelic Fraction by Droplet Digital PCR.
  Eric S. Christenson, W. Brian Dalton, David Chu, Ian Waters, Karen Cravero, Daniel J. Zabransky, Amy E. DeZern, Ben H o Park> ;Clinical Chemistry. 2017 Jan 1
• 52 citations
  Personalized Medicine in the Oncology Clinic: Implementation and Outcomes of the Johns Hopkins Molecular Tumor Board.
  W. Brian Dalton, Patrick M. Forde, Hyunseok Kang, Roisin M. Connolly, Vered Stearns, Christopher D. Gocke, James R. Eshleman, Jennifer E. Axilbund, Dana Petry, Cindy G...> ;JCO Precision Oncology. 2017 May 31
• 13 citations
  PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity
  Sarah Croessmann, Hong Yuen Wong, Daniel J. Zabransky, David Chu, D. Marc Rosen, Justin Cidado, Rory L. Cochran, W. Brian Dalton, Bracha Erlanger, Karen Cravero, Berry...> ;Breast Cancer Research and Treatment. 2017 Feb 11
• 9 citations
  A Polycythemia Vera JAK2 Mutation Masquerading as a Duodenal Cancer Mutation
  Justin Lee, Jennifer E. Axilbund, W. Brian Dalton, Daniel A. Laheru, Stanley Watkins, David Chu, Karen Cravero, Berry Button, Kelly Kyker-Snowman, Ian Waters, Christop...> ;Journal of the National Comprehensive Cancer Network. 2016 Dec 1
• 136 citations
  ESR1 mutations in circulating plasma tumor DNA from metastatic breast cancer patients
  David Chu, Costanza Paoletti, Christina L. Gersch, Dustin A. VanDenBerg, Daniel J. Zabransky, Rory L. Cochran, Hong Yuen Wong, Patricia Valda Toro, Justin Cidado, Sara...> ;Clinical Cancer Research. 2016 Feb 15
• HER2 missense mutations have distinct effects on oncogenic signaling and migration.
  Zabransky, D. J.,Yankaskas, C. L.,Cochran, R. L.,Wong, H. Y.,Croessmann, S.,Chu, D.,Kavuri, S. M.,Red Brewer, M.,Rosen, D. M.,Dalton, W. B.,Cimino-Mathews, A.,Cravero,...> ;Proc. Natl. Acad. Sci. U.S.A.. 2015 Oct 29
• NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability.
  Croessmann S, Wong HY, Zabransky DJ, Chu D, Mendonca J, Sharma A, Mohseni M, Rosen DM, Scharpf RB, Cidado J, Cochran RL, Parsons HA, Dalton WB, Erlanger B, Button B, C...> ;Proc. Natl. Acad. Sci. U.S.A.. 2015-09-15
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Abstracts/Posters

• Coagulopathy, Hypoxemia, and Mortality Outcomes in Newly Diagnosed Acute Myeloid Leukemia with Hyperleukocytosis Treated with Large Volume Leukapheresis
  William Brian Dalton, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019