WilliamGabrielHawkinsMD

PubMed

• The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer.
  Takaomi Hagi, Suwanna Vangveravong, Rony Takchi, Qingqing Gong, S Peter Goedegebuure, Herve Tiriac, Brian A Van Tine, Matthew A Powell, Dirk Spitzer, William G Hawkins> ;Scientific Reports. 2024 Mar 16
• ASO Author Reflections: A Role for Extended VTE Prophylaxis After Neoadjuvant Therapy and Distal Pancreatectomy for Pancreatic Adenocarcinoma.
  Keenan J Robbins, William G Hawkins> ;Annals of Surgical Oncology. 2024 May 1
• sc2MeNetDrug: A computational tool to uncover inter-cell signaling targets and identify relevant drugs based on single cell RNA-seq data.
  Feng, J., Goedegebuure, S., Zeng, A., Bi, Y., Wang, T., Payne, P., Ding, L., DeNardo, D., Hawkins, W., Fields, R., Li, F.> ;Plos Computational Biology. 2024 Jan 1
• 1 citations
  Neoadjuvant Chemotherapy is Associated with Increased Risk of Postoperative DVT After Distal Pancreatectomy for Pancreatic Adenocarcinoma: a NSQIP Analysis.
  Keenan J Robbins, Kenneth F Newcomer Jr, Erica K Barnell, Michael A Anzelmo, Jingxia Liu, William G Hawkins> ;Annals of Surgical Oncology. 2024 May 1
• Correction to: Comments on "Challenging Orthodoxy: Beyond the Critical View of Safety".
  Steven M Strasberg, L Michael Brunt, Ryan C Fields, Adnan Alseidi, William G Hawkins> ;Journal of Gastrointestinal Surgery. 2023 Jun 1
• 1 citations
  Impact of Prehabilitation on Postoperative Mortality and the Need for Non-Home Discharge in High-Risk Surgical Patients.
  Jorge G Zarate Rodriguez, Heidy Cos, Melanie Koenen, Jennifer Cook, Lacey Raper, Tracey Guthrie, Steven M Strasberg, William G Hawkins, Chet W Hammill, Ryan C Fields, ...> ;Journal of the American College of Surgeons. 2023 Sep 1
• 3 citations
  Safety, tolerability, and effectiveness of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in combination with standard chemotherapy for patients w...
  Lauren K Park, Kian-Huat Lim, Jonas Volkman, Mina Abdiannia, Hannah Johnston, Zack Nigogosyan, Marilyn J Siegel, Janet B McGill, Alexis M McKee, Maamoun Salam, Rong M ...> ;Cancer & Metabolism. 2023 May 18
• Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology.
  Usman Y Panni, Michael Y Chen, Felicia Zhang, Darren R Cullinan, Lijin Li, C Alston James, Xiuli Zhang, S Rogers, A Alarcon, John M Baer, Daoxiang Zhang, Feng Gao, Chr...> ;Cancer Immunology, Immunotherapy. 2023 Aug 1
• Comments on "Challenging Orthodoxy: Beyond the Critical View of Safety".
  Steven M Strasberg, L Michael Brunt, Ryan C Fields, Adnan Alseidi, William G Hawkins> ;Journal of Gastrointestinal Surgery. 2023 Jun 1
• 2 citations
  Postoperative Proton Pump Inhibitors are associated with a significantly higher rate of delayed gastric emptying after pancreatoduodenectomy.
  Usman Panni, Rohit Srivastava, Alice Bewley, Gregory A Williams, Ryan C Fields, Dominic E Sanford, William G Hawkins, Natasha Leigh, Chet W Hammill> ;HPB. 2023 Jun 1
• 22 citations
  Defactinib, Pembrolizumab, and Gemcitabine in Patients with Advanced Treatment Refractory Pancreatic Cancer: A Phase I Dose Escalation and Expansion Study.
  Andrea Wang-Gillam, Kian-Huat Lim, Robert McWilliams, Rama Suresh, Albert C Lockhart, Amberly Brown, Marcus Breden, Jad I Belle, John Herndon, Savannah J Bogner, Katri...> ;Clinical Cancer Research. 2022 Dec 15
• 2 citations
  Qualitative imaging features of pancreatic neuroendocrine neoplasms predict histopathologic characteristics including tumor grade and patient outcome.
  Motoyo Yano, Anup S Shetty, Greg A Williams, Samantha Lancia, Nikolaos A Trikalinos, Chet W Hammill, William G Hawkins, Amber Salter, Deyali Chatterjee> ;Abdominal Radiology. 2022 Dec 1
• How Biomarkers of Response to Chemotherapy Might Change Patient Management.
  William G Hawkins, Chet W Hammill, Samuel J Ballentine> ;Annals of Surgical Oncology. 2023 Feb 1
• 1 citations
  4,300 steps per day prior to surgery are associated with improved outcomes after pancreatectomy.
  Heidy Cos, Jorge G Zárate Rodríguez, Rohit Srivastava, Alice Bewley, Lacey Raper, Dingwen Li, Ruixuan Dai, Gregory A Williams, Ryan C Fields, William G Hawkins, Chenya...> ;HPB. 2023 Jan 1
• Cause and outcome of aborting a difficult laparoscopic cholecystectomy due to severe inflammation: a study of operative notes.
  Usman Y Panni, Gregory A Williams, Chet W Hammill, Dominic E Sanford, William G Hawkins, Steven M Strasberg> ;Surgical Endoscopy. 2022 Oct 1
• 50 citations
  Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer.
  Daniel Cui Zhou, Reyka G Jayasinghe, Siqi Chen, John M Herndon, Michael D Iglesia, Pooja Navale, Michael C Wendl, Wagma Caravan, Kazuhito Sato, Erik Storrs, Chia-Kuei ...> ;Nature Genetics. 2022 Sep 1
• 9 citations
  Malic Enzyme 1 Absence in Synovial Sarcoma Shifts Antioxidant System Dependence and Increases Sensitivity to Ferroptosis Induction with ACXT-3102.
  Caitlyn B Brashears, Bethany C Prudner, Richa Rathore, Katharine E Caldwell, Carina A Dehner, Jane L Buchanan, Sara E S Lange, Neal Poulin, Jennifer K Sehn, Jason Rosz...> ;Clinical Cancer Research. 2022 Aug 15
• 3 citations
  MR-Guided Radiation Therapy With Concurrent Gemcitabine/Nab-Paclitaxel Chemotherapy in Inoperable Pancreatic Cancer: A TITE-CRM Phase I Trial.
  Hyun Kim, Jeffrey R Olsen, Olga L Green, Re-I Chin, William G Hawkins, Ryan C Fields, Chet Hammill, Majella B Doyle, William Chapman, Rama Suresh, Benjamin Tan, Katrin...> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Jan 1
• 1 citations
  Increased Morbidity and Mortality After Hepatectomy for Colorectal Liver Metastases in Frail Patients is Largely Driven by Worse Outcomes After Minor Hepatectomy: It's...
  Natasha Leigh, Gregory A Williams, Steven M Strasberg, Ryan C Fields, William G Hawkins, Chet W Hammill, Dominic E Sanford> ;Annals of Surgical Oncology. 2022 Sep 1
• ASO Visual Abstract: Increased Morbidity and Mortality After Hepatectomy for Colorectal Liver Metastases in Frail Patients is Largely Driven by Worse Outcomes After Mi...
  Natasha Leigh, Gregory A Williams, Steven M Strasberg, Ryan C Fields, William G Hawkins, Chet W Hammill, Dominic E Sanford> ;Annals of surgical oncology. 2022 May 9
• Oligometastatic Rectal Adenocarcinoma Treated With Short-Course Radiation Therapy and Chemotherapy With Nonoperative Intent of the Primary for Locoregional Complete Re...
  Joshua P Schiff, Re-I Chin, Amit Roy, Lily Mahapatra, Hayley B Stowe, Neal Andruska, Yi Huang, Matthew Mutch, Ryan C Fields, William G Hawkins, Maria Doyle, Will Chapm...> ;Practical Radiation Oncology. 2022 May 5
• 6 citations
  Oncogenic Kras-Mediated Cytokine CCL15 Regulates Pancreatic Cancer Cell Migration and Invasion through ROS.
  Justin K Messex, Kiyah L A Adams, William G Hawkins, David DeNardo, Nabeel Bardeesy, Daniel D Billadeau, Geou-Yarh Liou> ;Cancers. 2022 Apr 26
• 8 citations
  Clinical classification of symptomatic heterotopic pancreas of the stomach and duodenum: A case series and systematic literature review.
  Michael T LeCompte, Brandon Mason, Keenan J Robbins, Motoyo Yano, Deyali Chatterjee, Ryan C Fields, Steven M Strasberg, William G Hawkins> ;World Journal of Gastroenterology. 2022 Apr 14
• 2 citations
  The targeted SMAC mimetic SW IV-134 augments platinum-based chemotherapy in pre-clinical models of ovarian cancer.
  Pratibha S Binder, Yassar M Hashim, James Cripe, Tommy Buchanan, Abigail Zamorano, Suwanna Vangveravong, David G Mutch, William G Hawkins, Matthew A Powell, Dirk Spitzer> ;BMC Cancer. 2022 Mar 12
• 4 citations
  Combination TIGIT/PD-1 blockade enhances the efficacy of neoantigen vaccines in a model of pancreatic cancer.
  Hui Peng, Lijin Li, Chong Zuo, Michael Y Chen, Xiuli Zhang, Nancy B Myers, Graham D Hogg, David G DeNardo, S Peter Goedegebuure, William G Hawkins, William E Gillanders> ;Frontiers in Immunology. 2022 Jan 1
• Join now to see all

Journal Articles

• Post-Discharge Phone Call Intervention After Pancreaticoduodenectomy  
  Darren R Cullinan, Chet Hammill, Ryan C Fields, Steven M Strasberg, William G Hawkins, Journal of The American College of Surgeons
• Intensity Modulated Radiation Therapy and Surgery for Management of Retroperitoneal Sarcomas: A Single-Institution Experience  
  Todd DeWees, Imran Zoberi, Jeffrey Olsen, Jeff Michalski, William Hawkins, BioMed Central
• Variations in Definition and Method of Retrieval of Complications Influence Outcomes Statistics after Pancreatoduodenectomy: Comparison of NSQIP with Non-NSQIP Methods  
  Sanford DE, Woolsey CA, Hall BL, Linehan DC, Hawkins WG, Fields RC, Strasberg SM, J Am Coll Surg, 9/1/2014
• Pancreatic adenocarcinoma, version 22014  
  Tempero MA, Malafa MP, Behrman SW, Benson AB 3rd, Casper ES, Chiorean EG, Chung V, Cohen SJ, Czito B, Engebretson A, Feng M, Hawkins WG, Herman J, Hoffman JP, Ko A, Ko..., J Natl Compr Canc Netw, 8/1/2014
• Natural History of Preoperative Subcentimeter Pulmonary Nodules in Patients With Resectable Pancreatic Adenocarcinoma: A Retrospective Cohort Study  
  Chang ST, Nguyen DC, Raptis C, Menias CO, Zhou G, Wang-Gillam A, Linehan DC, Hawkins WG, Strasberg SM, Fields RC, Ann Surg, 6/19/2014
• Conjugation to a SMAC mimetic potentiates sigma-2 ligand induced tumor cell death in ovarian cancer  
  Garg G, Vangveravong S, Zeng C, Collins L, Hornick M, Hashim Y, Piwnica-Worms D, Powell MA, Mutch DG, Mach RH, , Spitzer D, Hawkins WG, Mol Cancer, 3/1/2014
• Regional Lymphadenectomy Is Indicated in the Surgical Treatment of Pancreatic Neuroendocrine Tumors (PNETs)  
  Hashim YM, Trinkaus KM, Linehan DC, Strasberg SS, Fields RC, Cao D, Hawkins WG, Ann Surg, 11/18/2013
• A New Operative Approach for Type I Choledochal Cysts  
  Jin LX, Fields RC, Hawkins WG, Linehan DC, Strasberg SM, J Gastrointest Surg, 11/13/2013
• Synergistic Effects of Concurrent Blockade of PI3K and MEK Pathways in Pancreatic Cancer Preclinical Models  
  Zhong H, Sanchez C, Spitrzer D, Plambeck-Suess S, Gibbs J, Hawkins WG, Denardo D, Gao F, Pufahl RA, Lockhart AC, Xu M, Linehan D, Weber J, Wang-Gillam A, PLoS One, 10/1/2013
• A Study of Zoledronic Acid as Neo-Adjuvant, Perioperative Therapy in Patients with Resectable Pancreatic Ductal Adenocarcinoma  
  Sanford DE, Porembka MR, Panni RZ, Mitchem JB, Belt BA, Plambeck-Suess SM, Lin G, Denardo DG, Fields RC, Hawkins WG, Strasberg SM, Lockhart AC, Wang-Gillam A, Goedegeb..., J Cancer Ther, 5/1/2013
• Jaundice: an important, poorly recognized risk factor for diminished survival in patients with adenocarcinoma of the head of the pancreas  
  Strasberg SM, Gao F, Sanford D, Linehan DC, Hawkins WG, Fields R, Capenter DH, Brunt EM, Phillips C, HBP (Oxford), 4/22/2013
• The case for neoadjuvant therapy in locally advanced gastric cancer: comment on “multivisceral resection for locally advanced gastric cancer”  
  Hawkins WG, JAMA Surg, 4/1/2013
• Cost benefit analysis of mesh reinforcement of stapled left pancreatectomy  
  Idrees K, Edler JR, Linehan DC, Strasberg SM, Jacques D, Hamilton NA, Fields RC, Lambert D, Kymes S, Hawkins WG, HBP (Oxford), 2/1/2013
• Invited Commentary: Irreversible Electroporation for pancreatic cancer  
  Allen PJ and Hawkins WG, J Am Coll Surg, 9/1/2012
• A phase I study of IMP321 and gemcitabine as the front-line therapy in patients with advanced pancreatic adenocarcinoma  
  Wang-Gillam A, Plambeck-Suess S, Goedegebuure P, Simon PO, Mitchem JB, Hornick JR, Sorscher S, Picus J, Suresh R, Lockhart AC, Tan B, Hawkins WG, Invest New Drugs, 8/4/2012
• Microscopic margins and patterns of treatment failure in resected pancreatic adenocarcinoma  
  Gnerlich JL, Luka SR, Deshpande AD, Dubray BJ, Weir JS, Carpenter DH, Brunt EM, Strasberg SM, Hawkins WG, Linehan DC, Arch Surg, 8/1/2012
• Ki-67 predicts disease recurrence and poor prognosis in pancreatic neuroendocrine neoplasms  
  Hamilton NA, Liu TC, Cavatiao A, Mawad K, Chen L, Strasberg SS, Linehan DC, Cao D, Hawkins WG, Surgery, 7/1/2012
• Lysosomal Membrane Permeabilization is an Early Event in Sigma-2 Receptor Ligand Mediated Cell Death in Pancreatic Cancer  
  Hornick JR, Vangveravong S, Spitzer D, Abate C, Berardi F, Goedegebuure P, Mach RH, Hawkins WG, J Exp Clin Cancer Res, 5/1/2012
• Resection of tumors of the neck of the pancreas with venous invasion: the "Whipple at the Splenic Artery (WATSA)" procedure  
  Strasberg SM, Sanchez LA, Hawkins WG, Fields RC, Linehan DC, J Gastrointest Surg, 5/1/2012
• Multi-institutional analysis of pancreatic adenocarcinoma demonstrating the effect of diabetes status on survival after resection  
  Cannon RM, LeGrand R, Chagpar RB, Ahmad SA, McClaine R, Kim HJ, Rupp C, Cho CS, Brinkman A, Weber S, Winslow ER, Kooby DA, Chu CK, Staley CA, Glenn I, Hawkins WG, Pari..., HPB (Oxford), 4/1/2012
• Use of multifunctional sigma-2 receptor ligand conjugates to trigger cancer-selective cell death signaling  
  Spitzer D, Simon PO Jr, Kashiwagi H, Xu J, Zeng C, Vangveravong S, Zhou D, Chang K, McDunn JE, Hornick JR, Goedegebuure P, Hotchkiss RS, Mach RH, Hawkins WG, Cancer Res, 1/1/2012
• Radiologic and intraoperative detection of need for mesenteric vein resection in patients with adenocarcinoma of the head of the pancreas  
  Porembka MR, Hawkins WG, Linehan DC, Gao F, Ma C, Brunt EM, Strasberg SM, HPB (Oxford), 9/1/2011
• A technique of gastrojejunostomy to reduce delayed gastric emptying after pancreatoduodenectomy  
  Khan AS, Hawkins WG, Linehan DC, Strasberg SM, J Gastrointest Surg, 8/1/2011
• DISPACT trial: What do we learn from equivalency?  
  Hawkins WG, Alseidi A, Lancet, 4/1/2011
• Potential targets for pancreatic cancer immunotherapeutics  
  Dodson LF, Hawkins WG, Goedegebuure P, Immunotherapy, 4/1/2011
• Join now to see all

Books/Book Chapters

• Surg Oncol Clin N Am 
  Hawkins WG and Strasberg SMEdition 11th,2014
• The Washington Manual of Surgery 
  Sekhar Dharmarajan, Valerie J. Halpin, and William G. HawkinsEdition 5th,2008
• Textbook of Hepatology From Basic Science to Clinical Practice 
  Chapter: Cholangiocarcinoma 
  Strasberg SM and Hawkins WGEdition 3rd,2007
• Anatomic Principles and Surgical Techniques: Mastery of Surgery 
  Chapter: Reconstruction of the Bile Duct 
  Strasberg SM and Hawkins WGEdition 5th,2007
• Nutrition in the Critically Ill Patient. Critical Care Clinics 
  Chapter: Nutritional support of the septic patient 
  Wojnar MM, Hawkins WG, and Lang CHEditors: Lang CH, Abumrad NN.1995
• Join now to see all