YasushiKisanukiMD

PubMed

• 16 citations
  Primary Lateral Sclerosis (PLS) Functional Rating Scale: PLS‐Specific Clinimetric Scale
  Hiroshi Mitsumoto, Codruta Chiuzan, Madison Gilmore, Yuan Zhang, Zachary Simmons, Sabrina Paganoni, Yasushi Kisanuki, Lorne Zinman, Omar Jawdat, Eric J. Sorenson, Mary...> ;Muscle & Nerve. 2020 Feb 1
• 69 citations
  Diagnosis, treatment, and clinical outcomes in 43 cases with cerebrotendinous xanthomatosis.
  P. Barton Duell, Gerald Salen, Florian Eichler, Andrea E. DeBarber, Sonja L. Connor, Lise Casaday, Suman Jayadev, Yasushi Kisanuki, Patamaporn Lekprasert, Mary J. Mall...> ;Journal of Clinical Lipidology. 2018 Sep 1
• 15 citations
  Primary Lateral Sclerosis and Early Upper Motor Neuron Disease: Characteristics of a Cross-Sectional Population.
  Christina Fournier, Alyssa Murphy, Lorena Loci, Hiroshi Mitsumoto, Catherine Lomen-Hoerth, Yasushi Kisanuki, Zachary Simmons, Nicholas J. Maragakis, April McVey, Tawfi...> ;Journal of Clinical Neuromuscular Disease. 2016 Mar 1
• Lessons learned from fatal progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with natalizumab.
  Boster AL Nicholas JA Topalli I Kisanuki YY Pei W Morgan-Followell B Kirsch CF Racke MK Pitt D> ;JAMA Neurol. 2013 Mar 1
• Narcoleptic orexin receptor knockout mice express enhanced cholinergic properties in laterodorsal tegmental neurons.
  Kalogiannis M Grupke SL Potter PE Edwards JG Chemelli RM Kisanuki YY Yanagisawa M Leonard CS> ;Eur J Neurosci. 2010 Jul
• 77 citations
  Low Blood Pressure in Endothelial Cell–Specific Endothelin 1 Knockout Mice
  Yaz Y. Kisanuki, Noriaki Emoto, Takashi Ohuchi, Bambang Widyantoro, Keiko Yagi, Kazuhiko Nakayama, Rafal M. Kedzierski, Robert E. Hammer, Hiromi Yanagisawa, S. Clay Wi...> ;Hypertension. 2010 Jul 1
• Endothelial cell-derived endothelin-1 promotes cardiac fibrosis in diabetic hearts through stimulation of endothelial-to-mesenchymal transition.
  Widyantoro B Emoto N Nakayama K Anggrahini DW Adiarto S Iwasa N Yagi K Miyagawa K Rikitake Y Suzuki T Kisanuki YY Yanagisawa M Hirata K> ;Circulation. 2010 Jun 8
• 38 citations
  Histamine‐1 receptor is not required as a downstream effector of orexin‐2 receptor in maintenance of basal sleep/wake states
  Mari Hondo, Kanji Nagai, Kousaku Ohno, Yasushi Kisanuki, Jon T. Willie, Takeshi Watanabe, Masashi Yanagisawa, Takeshi Sakurai> ;Acta Physiologica. 2010 Mar 1
• Vascular endothelial cell-derived endothelin-1 mediates vascular inflammation and neointima formation following blood flow cessation.
  Anggrahini DW Emoto N Nakayama K Widyantoro B Adiarto S Iwasa N Nonaka H Rikitake Y Kisanuki YY Yanagisawa M Hirata K> ;Cardiovasc Res. 2009 Apr 1
• 200 citations
  Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity.
  Hiromasa Funato, Allen L. Tsai, Jon T. Willie, Yasushi Kisanuki, S. Clay Williams, Takeshi Sakurai, Masashi Yanagisawa> ;Cell Metabolism. 2009 Jan 7
• Late-onset mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes with bitemporal lesions.
  Kisanuki YY Gruis KL Smith TL Brown DL> ;Arch Neurol. 2006 Aug
• Increased sensitivity to acute and persistent pain in neuron-specific endothelin-1 knockout mice.
  Hasue F Kuwaki T Kisanuki YY Yanagisawa M Moriya H Fukuda Y Shimoyama M> ;Neuroscience. 2005
• Cardiomyocyte-specific endothelin A receptor knockout mice have normal cardiac function and an unaltered hypertrophic response to angiotensin II and isoproterenol.
  Kedzierski RM Grayburn PA Kisanuki YY Williams CS Hammer RE Richardson JA Schneider MD Yanagisawa M> ;Mol Cell Biol. 2003 Nov
• Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes.
  Willie JT Chemelli RM Sinton CM Tokita S Williams SC Kisanuki YY Marcus JN Lee C Elmquist JK Kohlmeier KA Leonard CS Richardson JA Hammer RE Yanagisawa M> ;Neuron. 2003 Jun 5
• Regulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells.
  Oike Y Ito Y Hamada K Zhang XQ Miyata K Arai F Inada T Araki K Nakagata N Takeya M Kisanuki YY Yanagisawa M Gale NW Suda T> ;Blood. 2002 Aug 15
• Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis.
  Isermann B Hendrickson SB Zogg M Wing M Cummiskey M Kisanuki YY Yanagisawa M Weiler H> ;J Clin Invest. 2001 Aug
• Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo.
  Kisanuki YY Hammer RE Miyazaki J Williams SC Richardson JA Yanagisawa M> ;Dev Biol. 2001 Feb 15
• Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.
  Chemelli RM Willie JT Sinton CM Elmquist JK Scammell T Lee C Richardson JA Williams SC Xiong Y Kisanuki Y Fitch TE Nakazato M Hammer RE Saper CB Yanagisawa M> ;Cell. 1999 Aug 20
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Journal Articles

• Diagnosis, treatment, and clinical outcomes in 43 cases with cerebrotendious xanthomatosis  
  Duell PB, Salen G, Eichler FS, DeBarber AE, Connor SL, Casaday L, Jayadev S, Kisanuki Y, Lekprasert P, Malloy MJ, Ramdhani RA, Ziajka PE, Quinn JF, Su KG, Geller AS, D..., J Clin Lipidol., 1/22/2018
• Teaching NeuroImages: Cerebrotendinous Xanthomatosis; A Rare Adult-Onset Lipid Storage Disease  
  Makary MS, Kisanuki YY*, Amin NN, Slone HW, Neurology, 1/1/2018
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  Shinagawa S, Okazaki T, Ikeda M, Yudoh K, Kisanuki YY*, Yanagisawa M, Kawahata K, Ozaki S, Sci. Rep., 1/3/2017
• Primary Lateral Sclerosis and Early Upper Motor Neuron Disease: Characteristics of a Cross-Sectional Population  
  Fournier CN, Murphy A, Loci L, Mitsumoto H, Lomen-Hoerth C, Kisanuki Y, Simmons Z, Maragakis NJ, McVey AL, Al-Lahham T, Heiman-Patterson TD, Andrews J, McDonnell E, Cu..., Journal of clinical neuromuscular disease, 1/1/2016
• Differential action of orexin receptors in brainstem cholinergic and monoaminergic neurons revealed by receptor knockouts; implications for orexinergic signaling in ar...  
  Kholmeier KA, Tyler CJ, Kalogiannis M, Ishibashi M, Kristensen MP, Gumenchuk I, Chemelli RM, Kisanuki YY*, Yanagisawa M, Leonard CS, Front Neurosci., 1/20/2013
• Lessons learnt from fatal progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with natalizumab  
  Boster AL, Nicholas JA, Topalli I, Kisanuki YY*, Pei W, Morgan-Followell B, Kirsch CF, Racke MK, Pitt D, JAMA Neurol., 1/1/2013
• Pathogenesis of autosomal dominant hereditary spastic paraplegia (SPG6) revealed by a rat model  
  Watanabe F, Arnold WD, Hammer RE, Ghodsizadeh O, Moti H, Schumer M, Hashmi A, Hernandez A, Sneh A, Sahenk Z, Kisanuki YY*, J Neuropathol Exp Neurol, 1/1/2013
• Cholinergic modulation of narcoleptic attacks in double orexin receptor knockout mice  
  Kalogiannis M, Hsu E, Willie JT, Chemelli RM, Kisanuki YY*, Yanagisawa M, Leonard CS, PLoS One, 1/13/2011
• Endothelial cell-derived endothelin-1 promotes cardiac fibrosis in diabetic hearts through stimulation of endothelial-tomesennchymal transition  
  Widyantoro B, Emoto N, Nakayama K, Anggrahini DW, Adiarto S, Iwasa N, Yagi K, Miyagawa K, RIkitake Y, Suzuki T, Kisanuki YY*, Yanagisawa M, Hirata K, Circulation, 1/8/2010
• Histamine-1 receptor is not required as a downstream effector of orexin-2 receptor in maintenance of basal sleep/wake states  
  Hondo M, Nagai K, Ohno K, Kisanuki Y, Willie JT, Watanabe T, Yanagisawa M, Sakurai T, Acta Physiol (Oxf)., 1/1/2010
• Low blood pressure in endothelial cell-specific endothelin 1 knockout mice  
  Kisanuki YY*, Emoto N, Ohuchi T, Widyantoro B, Yagi K, Nakayama K, Kedzierski RM, Hammer RE, Yanagisawa H, Williams SC, Richardson JA, Suzuki T, Yanagisawa M, Hypertension, 1/1/2010
• Narcoleptic orexin receptor knockout mice express enhanced cholinergic properties in lateralodorsal tegmental neurons  
  Kalogiannis M, Grupke SL, Potter PE, Edwards JG, Chemelli RM, Kisanuki YY*, Yanagisawa M, Leonard CS, Eur J Neurosci, 1/1/2010
• Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity  
  Funato H, Tsai AL, Willie JT, Kisanuki Y, Williams SC, Sakurai T, Yanagisawa M, Cell Metab., 1/7/2009
• Vascular endothelial cell-derived endothelin-1 mediates vascular inflammation and neointima formation following blood flow cessation  
  Anggrahini DW, Emoto N, Nakayama K, Widyantoro B, Adiarto S, Iwasa N, Nonaka H, RIkitake Y, Kisanuki YY*, Yanagisawa M, Hirata K, Cardiovasc Res., 1/1/2009
• Late-onset mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes with bitemporal lesions  
  Kisanuki YY*, Gruis KL, Smith TL, Brown DL, Arch Neurol, 1/1/2006
• Role of Endothelin 1 in the Pathogenesis of Chronic Chagasic Heart Disease  
  Tanowitz HB, Huang H, Jelicks LA, Chandra M, Loredo ML, Weiss LM, Factor SM, Shtutin V, Mukherjee S, Kitsis RN, Christ GJ, Wittner M, Sirani J, Kisanuki YY*, Yanagisawa M, Infection and Immunity, 1/1/2005
• The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance  
  Vicent D, Ilany J, Kondo T, Naruse K, Fisher SJ, Kisanuki YY*, Bursell S, Yanagisawa M, King GL, Kahn CR, J Clin Invest, 1/1/2003
• Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes  
  Willie JT, Chemelli RM, Sinton CM, Tokita S, Williams SC, Kisanuki YY*, Marcus JN, Lee C, Elmquist JK, Kohlmeier KA, Leonard CS, Richardson JA, Hammer RF, Yanagisawa M, Neuron, 1/1/2003
• Role of cardiac myocyte-derived endothelin-1 in chagasic cardiomyopathy: molecular genetic evidence  
  Huang H, Yanagisawa M, Kisanuki YY*, Jelicks LA, Chandra M, Factor SM, Wittner M, Weiss LM, Pestell RG, Shtutin V, Shirani J, Tanowitz HB, Clin Sci (Lond), 1/1/2002
• Tie-2 Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo  
  Kisanuki YY*, Hammer RE, Miyazaki J, Williams SC, Richardson JA, Yanagisawa M, Dev Biol, 1/1/2001
• Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation  
  Chemelli RM, Willie JT, Sinton CM, Elmquist JK, Scammel T, Lee C, Richardson JA, Williams SC, Xiong Y, Kisanuki Y, Fitch TE, Nakazato M, Hammer RE, Saper CB, Yanagisawa M, Cell, 1/1/1999
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Lectures

• ALSP 
  1/1/2018
• Cerebrotendinous Xanthomatosis 
  1/1/2016
• CADASIL 
  1/1/2011
• Pathophysiology and Therapeutic Approach in the Hereditary Spastic Paraplegia 
  1/1/2010
• MELAS 
  1/1/2009
• X-linked hereditary spastic paraplegia: SPG2 
  1/1/2008
• X-linked hereditary spastic paraplegia: SPG2 - a novel PLP1 mutation 
  1/1/2008
• Progressive Gait Disturbance in human and rodent 
  1/1/2008
• Adult-onset, autosomal dominant leukodystrophy 
  1/1/2007
• Research Presentation: Hereditary Spastic Paraplegia/SPG6 
  1/1/2006
• Non-diabetic Lumbosacral Polyradiculoneuropathy 
  1/1/2004
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