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Ai-Xuan Holterman, MD, Pediatric (General) Surgery, Chicago, IL

Ai-XuanLHoltermanMD

Pediatric (General) Surgery • Chicago, IL

Professor Emerita of Surgery and Pediatrics University of Illinois College of Medicine

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Summary

  • Dr. A. Holterman, Professor Emerita of Surgery at the University of Illinois College of Medicine, is a pediatric surgeon and a surgeon scientist. She attended Texas Christian University; pursued training for Medicine, Biomedical research, Surgery and Pediatric Surgery at the University of Texas at Southwestern Medical School, the University of Virginia Health System, the U of Montreal and the U of Washington in Seattle. She belongs to academic societies including the American Surgical Association, the Society of University Surgeons, the American Pediatric Surgical Association, and the American Association for the Study of Liver Diseases. Her research interests on the liver epithelial cells gene regulation and function were funded by NIH grants. She has translational research projects with clinical trials targeting obesity in severely obese adolescents, pediatric cholestatic liver diseases in the US, Asia and India. She has developed and implemented a course in interprofessional team-based initial assessment and management of pediatric surgical emergencies, targeting low resources health care facilities lacking in pediatric surgical expertise to enhance pediatric life-threatening illnesses and injuries. She is a founder member of a non-profit 501(c) 3 organization IPSAC-VN (International Pediatric Specialist Alliance for the Children of Vietnam) which engages in surgical capacity building, training and education, and research collaborations with major children’s hospitals in Vietnam. She also founded Prometheus, USA, a non profit organization devoted to the discovery, development and deployment of solutions to improve children’s health around the world in low- and middle-income countries LMIC by fostering and supporting innovative medical education, training, and research, and by narrowing these gaps in under resourced sites. She is actively engaged in Global Health, mentoring, research and clinical surgery.

Education & Training

  • Drexel University
    Drexel UniversityM, Executive Leadership in Acacemic Medicine, 2015 - 2016
  • Harvard Medical School
    Harvard Medical SchoolM, Global Clinical Research Scholar, 2014 - 2015
  • universiry of montreal, hospital ste justine
    universiry of montreal, hospital ste justineFellowship, pediatric surgery, 2005 - 2007
  • University of Virginia Medical Center
    University of Virginia Medical CenterResidency, Surgery, 1984 - 1991
  • University of Texas Southwestern Medical School
    University of Texas Southwestern Medical SchoolClass of 1984, md
  • Texas Christian University
    Texas Christian UniversityBA, Biology; Chemistry, Magna Cum Laude, 1975 - 1980

Certifications & Licensure

  • IL State Medical License
    IL State Medical License 1997 - 2026
  • IN State Medical License
    IN State Medical License 2003 - 2021
  • American Board of Surgery Surgery
  • American Board of Surgery Pediatric Surgery

Awards, Honors, & Recognition

  • VIP Marquis Who's Who in America
  • ELAM fellow
  • US Top Doctor Castle Connolly, 2017
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Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Autophagy modulates physiologic and adaptive response in the liver  
    Trinh Van Le, Nhung Hai Truong, Liver Research, 12/6/2023
  • Study protocol of!Phase 2 open-label multicenter randomized controlled trial for!granulocyte-colony stimulating factor (GCSF) in!post-Kasai Type 3 biliary atresia  
    HPA Nguyen, J Ren, M Butler, H Li, S Qazi, K Sadiq, HT Dao, and A Holterman, Ped Surg International, 4/7/2022
  • Academic pediatric surgery capacity building in Vietnam through PASS, a Pediatric Acute Surgical Support course  
    BU Nguyễn, Holterman M, Holterman A, Q Dinh, Frontiers in Surgery-Pediatric Surgery, 4/4/2022
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Books/Book Chapters

  • RUSH University Medical Center Review of Surgery 
    Chapter: Pediatric Surgery Review 
    Daley S, and Holterman ALEditors: Velasco, Bines, Deziel, McCarthy, Millikan, Prinz, and Sacclarides.ElsevierEdition 5th,2011
  • The Liver, Biology and Pathology 
    Chapter: Gene regulation and in vivo function of Liver Transcription Factors 
    Costa RH, Holterman AL, Rausa F. and Adami GEditors: Arias, Boyer, Fausto, Chisary, Schachter and Shafritz.Edition 4th,2001
  • Immunology, Biochemistry and Biotechnology, Volume III , Molecular Mechanisms of Immune Regulation 
    Chapter: T cell recognition of Class I molecules using gene transfection, mutagenesis, and Class I Transgenic mice 
    Engelhard VH, Bernhard EJ, Henderson R, Ridge JP, Strubb S, Holterman MJ, Le AT, Barbosa J, and Lacy EEditors: Tyle P and Srivastava R.VHC Publishers, New York1991
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Abstracts/Posters

  • Granulocyte-Colony Stimulating Factor (G-CSF) improves hepatic inflammation, fibrosis and attenuates the ductular reaction during biliary obstruction in mice.
    Trinh Van Le, Huy Quang Do, Minh Thanh Dang, Tien-Trieu Pham-Le, Luan Van Tran, Khon Chan Huynh, Ai-Xuan Le Holterman, and Nhung Hai Truong., American Association for the Study of Liver Disease Annual Meeting, Boston, MA, 11/2019
  • Pediatric Acute Surgical Support PASS-Piloting a multimodality curriculum for enhancing emergency pediatric surgical capacity at low resources hospitals in Vietnam
    G Barton, K Chen, G Deshpande, T Dinh, C Huy, T Khairallah, S Kryzaniak, C Nguyen, F Nguyen, and A Holterman, Pacific Association of Pediatric Surgeons 2017 conference, Seattle, 1/1/2017
  • Pediatric Acute Surgical Support PASS-Initial assessment for the multimodal course for teaching the initial response to pediatric acute surgical emergencies to medical...
    A Holterman *, G Barton, K Chen, G Deshpande, T Dinh, T Khairallah, S Kryzaniak, C Nguyen, F Nguyen, C Ta, and T Tran., American Pediatric Surgical Association 49th Annual Meeting, Palm Desert, CA, 5/2018
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Lectures

  • Moving forward in treating Biliary atresia- Doing more of the same? 
    International guest speaker, Indonesian Association of Pediatric Surgeons, Padang, October 2018
  • Updates on Biliary Atresia-Is it a surgical disease? 
    National meeting of Vietnam Association for Pediatric Surgeons - 10/2018
  • Global Innovation in Pediatric Surgery 
    Indonesian Association of Pediatric Surgeons, Balikpapan - 10/2017
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Press Mentions

  • How Dr. Mark Holterman Became a Force for International Pediatrics
    How Dr. Mark Holterman Became a Force for International PediatricsJanuary 17th, 2018
  • Thirty-Six Years After Fleeing Vietnam, Doctor Finds Herself in Peoria
    Thirty-Six Years After Fleeing Vietnam, Doctor Finds Herself in PeoriaJuly 15th, 2017
  • American Scientific article re the need for research support of clinicians in developing countries. Dr. Anh-Hoa Pham Nguyen, head of Pediatric Hepatology at the Vietnam National Children's Hospital is the leading local PI for 3 children's hospitals in VN in a clinical trial using a repurposed medication toward the treatment of a rare yet devastating congenital liver disease, Biliary Atresia
    American Scientific article re the need for research support of clinicians in developing countries. Dr. Anh-Hoa Pham Nguyen, head of Pediatric Hepatology at the Vietnam National Children's Hospital is the leading local PI for 3 children's hospitals in VN in a clinical trial using a repurposed medication toward the treatment of a rare yet devastating congenital liver disease, Biliary Atresia June 17th, 2022

Grant Support

  • Optimizing Pediatric Surgical Care in Low Resources Countries with Pediatric Acute Surgical Support curriculumUS VN Education Foundation2016–2017
  • Foxm1b And HNF-6 Regulation Of Liver Injury ResponseNational Institute Of Diabetes And Digestive And Kidney Diseases2006
  • Foxm1b And HNF-6 Regulation Of Liver Injury ResponseNational Institute Of Diabetes And Digestive And Kidney Diseases2005–2006
  • Molecular Response Of Bile Duct Cell To Bile Duct InjuryNational Institute Of Diabetes And Digestive And Kidney Diseases2002–2005
  • T Cell Responses To HLA Antigens In Transgenic MiceNational Institute Of Allergy And Infectious Diseases1987

Professional Memberships

  • american. surgical association
    Member
  • sociery of university surgeons
    Member
  • American association for the study of liver diseases
    Member
  • American College of Surgeons - ACS
    Member
  • American Pediatric Surgical Association
    Member
  • Pacific Association of Pediatric Surgeons
    Member

Other Languages

  • French, Vietnamese

External Links

  • Dropbox PASShttps://www.dropbox.com/s/gkd06wzt9tbo6jz/Holterman%20PAPS%20PASS%202017.pdf?dl=0
  • IPSACVietnamhttps://www.ipsacvietnam.org/
  • News cliphttp://www.pjstar.com/article/20110904/News/309049933

Dr. Ai-Xuan Holterman, Dr. Ai-Xuan Holterman, MD, Dr. A Holterman, Dr. Ai-Xuan L Holterman