AlejandroDavidBarreraMD

PubMed

• 10 citations
  Causal network inference from gene transcriptional time-series response to glucocorticoids.
  Jonathan Lu, Bianca Dumitrascu, Ian C. McDowell, Brian Jo, Alejandro Barrera, Linda K. Hong, Sarah M. Leichter, Timothy E. Reddy, Barbara E. Engelhardt> ;Plos Computational Biology. 2021 Jan 29
• 30 citations
  Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens.
  Joshua B. Black, Sean R. McCutcheon, Shataakshi Dube, Alejandro Barrera, Tyler S. Klann, Grayson A. Rice, Shaunak S. Adkar, Scott H. Soderling, Timothy E. Reddy, Charl...> ;Cell Reports. 2020 Dec 1
• 38 citations
  c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program
  Morgan E. Parker, Alejandro Barrera, Joshua D. Wheaton, Matthew K Zuberbuehler, David S.J. Allan, James R. Carlyle, Timothy E. Reddy, Maria Ciofani> ;The Journal of Experimental Medicine. 2020 Jan 6
• 53 citations
  Targeted transcriptional modulation with type I CRISPR–Cas systems in human cells
  Adrian Pickar-Oliver, Joshua B. Black, Mae M. Lewis, Kevin J. Mutchnick, Tyler S. Klann, Kylie A. Gilcrest, Madeleine J. Sitton, Christopher E. Nelson, Alejandro Barre...> ;Nature Biotechnology. 2019 Sep 23
• Bayesian estimation of genetic regulatory effects in high-throughput reporter assays.
  William H. Majoros, Young-Sook Kim, Alejandro Barrera, Fan Li, Xingyan Wang, Sarah J. Cunningham, Graham Johnson, Cong Guo, William L. Lowe, Denise M. Scholtens, M. Ge...> ;Bioinformatics. 2020 Jan 15
• 26 citations
  Human genome-wide measurement of drug-responsive regulatory activity
  Graham Johnson, Alejandro Barrera, Ian C. McDowell, Anthony D'Ippolito, William H. Majoros, Christopher M. Vockley, Xingyan Wang, Andrew S. Allen, Timothy E. Reddy> ;Nature Communications. 2018 Dec 21
• 58 citations
  Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids.
  Anthony D'Ippolito, Ian C. McDowell, Alejandro Barrera, Linda K. Hong, Sarah M. Leichter, Luke C. Bartelt, Christopher M. Vockley, William H. Majoros, Alexias Safi, Li...> ;Cell Systems. 2018 Aug 22
• 72 citations
  Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding.
  Ian C. McDowell, Alejandro Barrera, Anthony D'Ippolito, Christopher M. Vockley, Linda K. Hong, Sarah M. Leichter, Luke C. Bartelt, William H. Majoros, Lingyun Song, Al...> ;Genome Research. 2018 Aug 10
• 40 citations
  PRiMeUM: A Model for Predicting Risk of Metastasis in Uveal Melanoma.
  Jorge Vaquero-Garcia, Emilie Lalonde, Kathryn G. Ewens, Jessica Ebrahimzadeh, Jennifer Richard-Yutz, Carol L. Shields, Alejandro Barrera, Christopher J Green, Yoseph B...> ;Investigative Ophthalmology & Visual Science. 2017 Aug 1
• 21 citations
  Decoding the role of regulatory element polymorphisms in complex disease
  Christopher M. Vockley, Alejandro Barrera, Timothy E. Reddy> ;Current Opinion in Genetics & Development. 2017 Apr 1
• 244 citations
  A new view of transcriptome complexity and regulation through the lens of local splicing variations
  Jorge Vaquero-Garcia, Alejandro Barrera, Matthew R. Gazzara, Juan González-Vallinas, Nicholas F. Lahens, John B. Hogenesch, Kristen W. Lynch, Yoseph Barash> ;Elife. 2016 Feb 1
• 831 citations
  Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
  Elena Sotillo, David M. Barrett, Kathryn L. Black, Asen Bagashev, Derek A. Oldridge, Glendon S. Wu, Robyn T. Sussman, Claudia Lanauze, Marco Ruella, Matthew R. Gazzara...> ;Cancer Discovery. 2015 Dec 1
• 20 citations
  Analysis of the protein domain and domain architecture content in fungi and its application in the search of new antifungal targets.
  Alejandro Barrera, Ana Alastruey-Izquierdo, Maria Jesus Martin, Isabel Cuesta, Juan Antonio Vizcaíno> ;Plos Computational Biology. 2014 Jul 17
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