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Office
B425 Clinical Center
788 Service Road
East Lansing, MI 48824Phone+1 517-353-5100Fax+1 517-432-9471- Is this information wrong?
Summary
- I am a physician-scientist and an entrepreneur. I am the incoming Chair of Medicine at Michigan State University and Director of Clinician Scientist Development at Henry Ford Health.
My research functions at the intersection of chemical biology, developmental biology, stem cell biology, and cardiovascular biology. Among my scientific contributions is the discovery of the role of Phosphoinositide 3-kinases (PI3K) in vein specification during vasculogenesis, which foreshadowed aberrant PI3K activation as a common cause of clinical venous malformations. I also discovered the first small molecule inhibitor of bone morphogenetic protein (BMP) signaling, which directly catalyzed the development of a clinical stage therapeutic program for devastating human diseases. My ongoing investigations studies include unraveling the essential role of centrosome reorganization in postnatal heart maturation, and developing novel therapies targeting of a key pro-oncogenic signaling pathway activated downstream of Warburg Effect. I edited one of the first books focused on chemical biology of stem cell and regenerative medicine, and a book covering the latest methods in chemical biology. I am the Specialty Chief Editor of Frontiers in Drug Discovery. I am an elected member of the American Society for Clinical Investigation (ASCI) and a Fellow of the American Association for the Advancement of Science (AAAS). I am a passionate advocate for medical education, having served as the Chair of the Scientific Committee and on the Board of Directors of the Sarnoff Foundation for Cardiovascular Research. Prior to MSU, I was the Melvin Sharoky, MD, Professor of Medicine, Co-Chief of Cardiovascular Medicine, and Director of Cardiology Research at the University of Maryland School of Medicine. Prior to that, I was on faculty at Vanderbilt University and Harvard Medical School. My clinical expertise is in cardiovascular genetics and inherited cardiomyopathies.
Education & Training
- Massachusetts General HospitalFellowship, Cardiovascular Disease, 2001 - 2004
- Yale-New Haven Medical CenterResidency, Internal Medicine, 1998 - 2001
- Yale School of MedicineClass of 1998
Certifications & Licensure
- MI State Medical License 2023 - 2026
- MD State Medical License 2018 - 2024
- TN State Medical License 2006 - 2019
- MA State Medical License 2001 - 2008
- American Board of Internal Medicine Cardiovascular Disease
Awards, Honors, & Recognition
- Fellow, AAAS American Association for the Advancement of Science, 2020
- Fellow, American Heart Association AHA, 2013
- American Society for Clinical Investigation Inductee ASCI, 2013
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Publications & Presentations
PubMed
- 11 citationsAssociation of Incident Cardiovascular Disease With Time Course and Cumulative Exposure to Multiple Risk Factors.Michael J Domanski, Colin O Wu, Xin Tian, Ahmed A Hasan, Xiaoyang Ma, Yi Huang, Rui Miao, Jared P Reis, Sejong Bae, Anwar Husain, David R Jacobs Jr, Norrina B Allen, M...> ;Journal of the American College of Cardiology. 2023 Mar 28
- 2 citationsImpaired Reorganization of Centrosome Structure Underlies Human Infantile Dilated Cardiomyopathy.Young Wook Chun, Matthew Miyamoto, Charles H Williams, Leif R Neitzel, Maya Silver-Isenstadt, Adrian G Cadar, Daniela T Fuller, Daniel C Fong, Hanhan Liu, Robert Lease...> ;Circulation. 2023 Apr 25
- 1 citationsLongitudinal Echocardiogram Imaging in the First Genetically Modified Porcine to Human Cardiac Xenotransplant.Susie N Hong, Muhammad M Mohiuddin, Manjula Ananthram, Cullen Soares, Corbin E Goerlich, Timm L Dickfeld, Peter Hanna, Charles C Hong, Michael Benitez, Susan M Joseph,...> ;JACC. Cardiovascular Imaging. 2023 Apr 1
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Other
- Heart Failure, Hope, and the Hurdles Ahead for XenotransplantationCharles C. Hong, TCTMD.com
https://www.tctmd.com/news/heart-failure-hope-and-hurdles-ahead-xenotransplantation
2/4/2022
Authored Content
- Heart Failure, Hope, and the Hurdles Ahead for XenotransplantationFebruary 2022
Press Mentions
- Research Could Lead to Potential New Ways to Predict and Prevent Stroke in Young AdultsSeptember 1st, 2022
- Your Blood Type Can Predict Your Stroke Risk Before Age 60August 31st, 2022
- Improving West Baltimore Cardiovascular HealthAugust 4th, 2022
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Professional Memberships
- Member
- Stanley J. Sarnoff FoundationMember
- Paul Dudley White SocietyMember
Other Languages
- Korean
External Links
- Hong Profilehttps://www.medschool.umaryland.edu/profiles/Hong-Charles/
- Hong Lab Profilehttps://www.medschool.umaryland.edu/hong-lab/
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