CuthbertOrmondSimpkinsIIMDFACS

PubMed

• Efficacy and safety of phospholipid nanoparticles (VBI-S) in reversing intractable hypotension in patients with septic shock: a multicentre, open-label, repeated measu...
  Kristopher Roach, Luis Diaz-Caballero, Daniel Haase, Mukesh Kumar, Harven DeShield, Juan Rodriguez, Prashanth Anamthathmakula, Nik Hurt, Bhaswati Mukherjee, Krishna Ta...> ;Eclinicalmedicine. 2024 Feb 1
• 2 citations
  Intra-Arterial Perimortem Resuscitation Using a Micellar Colloid
  Cuthbert Simpkins, Krishna Talluri, Mallory Williams> ;Military Medicine. 2016 May 9
• 1 citations
  Quantitation of dissolved gas content in emulsions and in blood using mass spectrometric detection.
  Everett D. Grimley, Nicole Turner, Clayton Newell, Cuthbert O. Simpkins, Juan Rodriguez> ;Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 2011 Jun 1
• 3 citations
  Histidine inhibits the degradation of cells suspended in Ringer's lactate.
  Cuthbert O. Simpkins, Viktoriya Ekshyyan, Brad Snyder> ;The Journal of Trauma. 2007 Sep 1
• 10 citations
  Heterogeneity in the effect of albumin and other resuscitation fluids on intracellular oxygen free radical production.
  Cuthbert O. Simpkins, Donnie T. Little, Andrew Brenner, January A. Hill, John A. Griswold> ;The Journal of Trauma. 2004 Mar 1
• Cyclic gmp is a measure of physiologic stress.
  Keith Hunter, Gagan J. Singh, Cuthbert O. Simpkins> ;Journal of the National Medical Association. 2001 Jul 1
• 8 citations
  ß-endorphin modulates calcium channel activity in human neutrophils
  Denise L. Mazorow, Cuthbert O. Simpkins, David B. Millar> ;Journal of Neuroimmunology. 1994 Feb 1
• 13 citations
  Effect of metallothionein I on mitochondrial oxygen consumption.
  Cuthbert O. Simpkins, Zhao Hao-Liao, Cynthia A. Torrence> ;Life Sciences. 1994 Jan 1
• 9 citations
  Reduction of cytochrome c by fragments of heat shock protein 70
  Cuthbert O. Simpkins, Kenneth W. Fogarty, Patson T. Nhamburo> ;Life Sciences. 1993 Jan 1
• 10 citations
  Metallothionein I reduction of cytochrome c
  Cuthbert O. Simpkins, Philippe Eudaric, Cynthia A. Torrence, Zhen Yang> ;Life Sciences. 1993 Jan 1
• 2 citations
  Human erythrocytes have binding sites for beta-endorphin.
  Cuthbert O. Simpkins, B. P. Chenet, Y. H. Kang, D. L. Mazorow, D. B. Millar, V. W. Hollis> ;Journal of the National Medical Association. 1989 Nov 1
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Journal Articles

• Intra-arterial Perimortem Resuscityation Using A Micellar Colloid  
  Simpkins C, Talluri K, Williams M, Military Medicine, 1/1/2016
• Soybean Oil: A Potentailly New Intravascular Perfusate  
  Armbruster M, Grimley E, Rodriguez J, Nacionales D, Efron P, Moldawer L, Papadopoulos K, Ungaro R, Cuenca A, Simpkins C., Perfusion, 12/20/2012
• Soybean Oil: A Potentially New Intravascular Infiltrate  
  Armbruster M, Grimley E, Rodriguez J, Nacionales D, Efron P, Moldawer L, Papadopoulos K, Ungaro R, Cuenca A, Simpkins C, Perfusion, 1/1/2012
• Quantitation of Dissolved Gas Content in Emulsions and in Blood Using Mass Spectrometric Detection  
  Grimley E, Turner N, Newell C, Simpkins C, Rodriguez J, J. Chromatgraphy B Analyt Technol Biomed Life Sci, 1/1/2011
• Histidine Inhibits the Degradation of Cells Suspended in Ringer's Lactate  
  Simpkins CO, Ekshyyan V, Snyder B, J. Trauma, 1/1/2007
• Heterogeneity in the Effect of Albumin and Other resuscitation Fluids on Intracellular Oxygen Free Radical Production  
  Simpkins CO, Little D, Brenner A, Hill J, Griswold G, J. Trauma-Injury, Infection, and Critical Care, 1/1/2004
• Correlation Between cGMP and Gaseous Mediators in Critically-ill Patients  
  Hunter K, Singh G, Uaeniga I, Wyche M, Simpkins CO, J. Natl. Med. Assoc., 1/1/2001
• Inhibition of insulin release from pancreatic islets of metallothionein-null mice  
  Laychock S, Duzen J, Simpkins CO, Mol. Cell. Endocrinol., 1/1/2000
• Spectrophotometric Measurement of Diagnostic Peritoneal Lavage Fluid Red Blood Cell Count  
  Manka M A, Moscati R M, Mayrose J, Christiansen G M, Treadway R, Simpkins C, Academic Emergency Medicine, 1/1/1999
• Measurement of self-esteem in repeat assault victims  
  Conti CT, Moncure M, Hines J, Clack Z, Smith T, Simpkins CO, J. Natl. Med. Assoc., 1/1/1998
• Metallothionein-induced increase in mitochondrial inner membrane permeability  
  Simpkins CO, Lloyd T, Li S, Balderman S, J. Surg. Res., 1/1/1998
• Synergistic inhibition of mitochondrial oxygen consumption by metallothionein 1 and calcium  
  Simpkins CO, Balderman SC, Mensah EA, J. Surg. Res., 1/1/1998
• Opposite effects of metallothionein I and spermine on mitochondrial function  
  Simpkins CO, Liao ZH Gebrehiwot R, Tyndall JA, Torrence CA, Fonong T, Balderman, SC, Mensah FA, Skolove PM, Life Sciences, 1/1/1996
• Metallothionein reduction of cytochrome c  
  Simpkins CO, Eudaric F, Torrence C, Yang Z, Life Sciences, 1/1/1994
• Beta-endorphin modulates calcium channel activity in human neutrophils  
  Maxzarow DL, Simpkins CO, Millar DB, J. Neuroimmunology, 1/1/1994
• Evidence that carbon monoxide is a mediator of critical illness  
  Hunter K, Eudaric P, Simpkins CO, Cellular and Molecular Biol, 1/1/1994
• Metallothionein is an uncoupler of oxidative phosphorylation  
  Simpkins CO, Torrence CA, Liao ZH, Life Sciences, 1/1/1994
• Reduction of cytochrome c by fragments of heat shock protein 70  
  Simpkins CO, Fogarty KW, Nhamburo P, Life Sciences, 1/1/1993
• Recurrent intentional injury  
  Goins WA, Thompson J, Simpkins CO, J. Natl. Med. Assoc., 1/1/1992
• Interaction between cytochrome c and di- and tripeptides  
  Simpkins CO, Williamson G, Moore C, Life Sciences, 1/1/1991
• A new cytochrome C reducing dipeptide  
  Simpkins CO, J.Natl. Med. Assoc., 1/1/1990
• Prostaglandin D2 modulates human neutrophil intracellular calcium flux and inhibits superoxide release via its ring carbonyl  
  Simpkins CO, Mazorow DL, Alailima JT, Tate EA, Sweatt W, Johnson M, Shariff K, Millar DB, Life Sciences, 1/1/1990
• Beta-endorphin receptors are distributed nonuniformly on human erythrocytes  
  Simpkins CO, Chenet B , Kang Y , Ho11i s V, J. Natl. Med. Assoc., 1/1/1989
• Phospholipase C activity in human polymorphonuclear leukocytes: Partial characterization and effect of indomethacin  
  Shakir K, Simpkins CO, Gartner SL, Sobel DO, Williams TJ, Enzyme, 1/1/1989
• Beta-endorphin and lipopolysaccharide interactions with human neutrophils  
  Simpkins CO, Tate EA, Alailima SA, J. Natl. Med. Assoc., 1/1/1988
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Books/Book Chapters

• Shackleford's "Surgery of the Alimentary Tract" 
  Chapter: Management of Hepatobiliary Trauma 
  Page 1659 - 1669Simpkins, CO, Nawabi A, Zibari GBEdition 6th,2007
• Mitochondria.. Ubiquinone (Coenzyme Q: Biochemical, Functional, Medical, and Therapeutic Aspects in Human Health and Disease) 
  Chapter: Coenzyme Q in Sepsis. 
  Simpkins COEditors: R. Chopra, M. Ebadi, and J. Karwah.Prominent Press2001
• Cellular and Molecular Biology 
  Chapter: Metallothionein in human disease. 
  Page 462 - 488Simpkins CO2000
• Proceedings of the Fourth International Metallothionein Meeting 
  Chapter: Metal composition is a determinate of the opening of the mitochondrial permeability pore. 
  Simpkins CO, Lloyd T, Balderman SCHirkhauser Verlag, Switzerland1998
• Stress and Immunity 
  Chapter: "Erythrocyte-opioid Peptide Interactions" 
  Simpkins COEditors: Plotnikoff, Murgo, Faith, Wybran.CRC Press1991
• "Black Men of Amherst" 
  Chapter: Foreword 
  Simpkins CO, Harold Wade1976
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Abstracts/Posters

• Lipid Micelle Emulsions For Resuscitation of Hemorrhagic Shock: Size Matters.
  Williams M, Simpkins CO, Military Health System Research Symposium, 1/1/2015
• Micellar Colloid Is Superior to Albumin For Resuscitation.
  Simpkins CO, Military Health System Research Symposium, 1/1/2014
• Vivasure: An Oxygen-Carrying Lipid Emulsion for Resuscitation.
  Simpkins CO, Rodriguez J, Circulation, 1/1/2009
• Reperfusion Does not Correct Acute Heat Deficit in Short Term Intestinal Ischemia.
  Kelly E, Matthew J, Blass A, Rodrigruez J, Soybel DI, Simpkins CO, Academic Surgical Congress, 1/12/2008
• Infrared Emision as a Monitor of Metabolism in Hemorrhagic Shock.
  Kelly E, Matthew J, Blass A, Rodriguez J, Soybel DI, Simpkins CO, Academic Surgical Congress, 1/12/2008
• Potential Role for Arterial Infusion and Lipid Emulsions in Cardiopulmonary Resuscitation after Hemorrhagic Shock.
  Simpkins CO, Ekshyyan V, Youssef, A, Meeting of the Eastern Association for the Surgery of Trauma, 1/1/2008
• Comparing various Fluids in the Intra-arterial Resuscitation of Cardiac Arrested Mice Due to Hemorrhagic Shock.
  Youssef A, Ekshyyan V, Simpkins C, Society of Critical Care Medicine, 1/1/2008
• Intra-arterial Fluid Infusion Restores Cardiac Contraction in Cardiac Arrest Due to Cardiac Arrest in Mice.
  Youssef A, Ekshyyan V, Simpkins C, Academic Surgical Congress, 1/1/2008
• The Integration of Flexion/Extension Cervical CT Scanning in the Trauma Protocol.
  Patwarden R, Shamieh S, Cardenas R, Simpkins C, Sadasavan K, Turnage R, Nanda A, American Association of Neurological Surgeons, 1/1/2006
• Intra-aortic Balloon Pump Reduces Blood Lactate in Septic Shock.
  Robinson M, Haldorsson A, Holand M, Simpkins C, Surgical Infection Society, 1/1/2004
• Adverse Effects of Resuscitation Fluids.
  Simpkins CO, Little D, Brenner A, Hill J, Griswold G, Eastern Association for the Surgery of Trauma, 1/1/2003
• Effect of Long-Term Suspension in Resuscitation Fluid on Cell Survival and Mitochondrial Membrane Polarity.
  Simpkins C, Waris W, DiGiacomo G, Shaftan G, Corisitsidis G, Shock Society, 1/1/2001
• Metallothionein expression in pancreatic islets and beta cells and possible role in insulin secretion.
  Laychock SG, Duzen J, Simpkins CO, Federation of American Societies for Experimental Biology, 1/1/1999
• Survivors of trauma: Victims of urban violence.
  Scaggs, R., Rapp, L. A., Dulmus, C. N., & Wodarski, J. S., International Conference on Research for Social Work Practice, North Miami, FL, 1/1/1998
• Children of gunshot victims: a study of psychiatric symptoms.
  Dulmus CN, Rapp TEA, Wodarski JS, Simpkins CO, Second International Conference on social Work in Health and Mental Health, 1/1/1998
• Violently victimized youth.
  Rapp LA, Dulmus CN, Wodarski JS, Simpkins CO, Second International Conference on social Work in Health and Mental Health, 1/1/1998
• Targeted disruption of metallothionein 1 and 2 genes increases sensitivity to sepsis.
  Simpkins CO, Hickox D, Balderman S, Choo K, Russo T, Shock Society, 1/1/1998
• Crime and violence prevention through violently victimized youth.
  Rapp LA, Dulmus CN, Wodarski JS, Simpkins CO, Academy of Criminal Justice Sciences, 1/1/1998
• Increased susceptibility to E. coli and diminished Tcell responsiveness in metallothionein null mice.
  Simpkins CO, Morey S, Hickox D, Russo T, Balderman S, Michalska A, Choo K, Rittenhouse Diakun K, International Conference on Metal Binding Proteins in Biology, 1/1/1998
• hospital based violence prevention program.
  Simpkins CO, Renford L, Francis CIA, American Public Health Association, 1/1/1998
• Metallothionein I induced opening of the mitochondria permeability pore.
  Simpkins CO, Lloyd T, Li S, Balderman SC, Surgical Infection Society, 1/1/1997
• Metal composition is a determinant of the metallothionein induced opening of the mitochondrial permeability pore.
  Simpkins CO, Lloyd T, Li S, Balderman SC, Fourth International Metallothionein Meeting, 1/1/1997
• Substance abuse in violently victimized adolescents.
  Rapp LA, Dulmus CN Wodarski JS, Simpkins CO, Research Society on Alcoholism, 1/1/1997
• A comprehensive interpersonal treatment technology for Conduct Disorder and Depression in the adolescent life stage.
  Rapp, L. A., Dulmus, C. N., & Wodarski, J. S., International Conference for Advancement of Private Practice of Clinical Social Work, Jackson Hole, WY, 1/1/1997
• Substance abuse in violently victimized adolescents.
  Rapp, L. A., Dulmus, C. N., Wodarski, J. S., & Simpkins, C. O., 1997 Annual Meeting of the Research Society on Alcoholism, San Francisco, CA, 1/1/1997
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Lectures

• Lipid Micelles as Colloids for Hemorrhagic Shock. 
  1/1/2012
• Penetrating Trauma 
  1/1/2005
• Mechanical Ventilation 
  1/1/2005
• "Life's Mission" 
  1/1/2005
• "Violence Prevention" 
  1/1/2005
• "Trauma Centers: The Intersection of Technology and Health Care" 
  1/1/2004
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Other

• "Coltrane and Me: Why Jazz is My Religion and Wally's Is My Temple" 
  Simpkins CO, Harveard Medicine Magazine
  1/1/2017
• Tranography: A Juxtaposition of Apparent Conflicts Between Two Biographies Publication 
  Simpkins CO, "All About Jazz" (Internet)
  1/1/2003
• In the Spirit of John Coltrane 
  Simpkins CO, Liner Notes for new CD of Musician/Composer Sonny Fortune
  1/1/2000
• Coltrane: A Biography 
  Simpkins CO, Biography of John Coltrane, published by Herndon House
  1/1/1975
• God's Touch 
  Simpkins CO, Chapter from Coltrane: A Biography Published by Impressions: Magazine of the Arts
  1/1/1975
• "Wally's" 
  Simpkins CO, The Baystate Banner; Black Creation
  1/1/1972
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