Skip to main content
Daniel Chen, MD, Oncology, San Carlos, CA

Daniel S. Chen MD PhD

Melanoma


Founder and CEO, Synthetic Design Lab, Inc Founding Partner, Genesis BioCapital

Join to view full profile
  • Synthetic Design LabSan Carlos, CA 94070

Dr. Chen is on Doximity

As a Doximity member, you’ll join more than three million U.S. healthcare professionals—including 85+% of physicians, and 2/3 of all NPs and PAs—in a private, secure network.

  • Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
  • Connect with colleagues in the same hospital or clinic.
  • Read the latest clinical news, personalized to your specialty.

Summary

  • Dr. Daniel Chen is Physician Scientist, Medical Oncologist and Immunologist based in San Carlos, CA, specializing in melanoma and the development of novel treatments for Cancer and other human diseases. He completed his medical education at the Keck School of Medicine at the University of Southern California, followed by a residency, fellowship and post-doctorate at Stanford University. He holds a BS in Biology from MIT. Dr. Chen is the Founder and CEO of Synthetic Design Lab and a founding partner at Genesis BioCapital, LLC, and previously served as an Attending Physician at Stanford Health Care. His other previous roles include Chief Medical Officer at IGM Biosciences and Vice President, Global Head of Cancer Immunotherapy at Genentech/Roche. Dr. Chen's expertise encompasses cancer immunotherapy, novel engineered therapeutics, oncology, virology, and immunology. He has been published in leading journals, including Nature and Immunity, and his work, including "Oncology meets Immunology: The Cancer-Immunity Cycle", has received numerous citations. Additionally, Dr. Chen has contributed to many clinical trials focused on immunotherapy and led the development of TECENTRIQ (anti-PD-L1) from first in human studies to multiple global approvals.

Education & Training

  • UCLA David Geffen School of Medicine/UCLA Medical Center
    UCLA David Geffen School of Medicine/UCLA Medical CenterResidency, Gastroenterology, 2017 - 2023
  • Stanford Health Care-Sponsored Stanford University
    Stanford Health Care-Sponsored Stanford UniversityFellowship, Medical Oncology, 2000 - 2003
  • Stanford Health Care-Sponsored Stanford University
    Stanford Health Care-Sponsored Stanford UniversityResidency, Internal Medicine, 1998 - 2000
  • Keck School of Medicine of the University of Southern California
    Keck School of Medicine of the University of Southern CaliforniaClass of 1998
  • Massachusetts Institute of Technology
    Massachusetts Institute of TechnologyBS, Biology, 1986 - 1990

Certifications & Licensure

  • CA State Medical License
    CA State Medical License 1999 - 2024

Awards, Honors, & Recognition

  • https://www.pinterest.com/dschen5/dsc/

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Differential Regulation of PD-L1 Expression by Immune and Tumor Cells in NSCLC and the Response to Treatment with Atezolizumab (Anti–PD-L1)  
    Alan Sandler, David S Shames, Hartmut Koeppen, Jamie Chaft, Scott N Gettinger, Alexander Spira, Daniel S Chen, Naiyer A Rizvi, David R Spigel, Proceedings of the National Academy of Sciences
  • Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial  
    Fehrenbacher, L, Spira, A, Ballinger, M, Kowanetz, M, Vansteenkiste, J, Mazieres, J, Park, K, Smith, D, Artal-Cortes, A, Lewanski, C, Braiteh, F, Waterkamp, D, He, P, ..., Lancet, 1/1/2016

Abstracts/Posters

  • High Avidity IgM-Based CD20xCD3 Bispecific Antibody (IGM-2323) for Enhanced T-Cell Dependent Killing with Minimal Cytokine Release
    Daniel Chen, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Press Mentions

  • Too Many Trials, Not Enough Patients
    Too Many Trials, Not Enough PatientsNovember 18th, 2019
  • Drug Giant Tries New Tactic to Fight Cancer
    Drug Giant Tries New Tactic to Fight CancerMay 27th, 2019
  • A Cure for Cancer: How to Kill a Killer
    A Cure for Cancer: How to Kill a KillerNovember 4th, 2018

Committees

  • Co-Organizer, SITC Immuno Engineering Initiative 2022 - Present
  • co-organizer, SITC Deep Dive Series 2020 - Present
  • Board of Directors, SITC (Society of Immunotherapy for Cancer) 2018 - 2022
  • Co-Chair, CRI Cancer Immunotherapy Consortium 2016 - 2020
  • Committee Chair, Society for Immunotherapy of Cancer 2012 - 2018

Professional Memberships

Other Languages

  • Chinese (Mandarin)

Industry Relationships

  • Founder, Bionic Cell Medicines2022 - Present
  • Founder and CEO, Synthetic Design Lab2022 - Present
  • Founder, Engenuity Life Sciences2022 - Present
  • Chief Medical Officer, IGM Biosciences2018 - Present
  • Vice President, Global Head for Cancer Immunotherapy, Genentech/Roche2006 - 2018

Viewing the full profile is available to verified healthcare professionals only.

Find your profile and take control of your online presence: