Overview of Dr. Alenghat Dr. Alenghat is an investigative cardiologist at University of Chicago. He received his medical degree from Harvard Medical School, completed his medicine residency and cardiology fellowship at Brigham & Women's Hospital, and has been in practice for 12 years. He specializes and conducts translational research in preventive cardiology, vascular biology, and atherosclerosis.
Education & Training Brigham and Women's Hospital Fellowship, Cardiovascular Disease, 2007 - 2012
Brigham and Women's Hospital Residency, Internal Medicine, 2005 - 2007
Harvard Medical School Class of 2005
Harvard University PhD, Biophysics, 2005
Harvard University SB, Engineering Sciences, Summa Cum Laude, 1997
Certifications & Licensure Awards, Honors, & Recognition Academic Cardiology Leadership Council American College of Cardiology, 2018-2023 Rory R Childers Teaching Award University of Chicago Cardiology, 2018 Young Physician-Scientist Award American Society for Clinical Investigation (ASCI), 2018 Fellow of the American College of Cardiology (FACC) American College of Cardiology, 2017 ATVB Young Investigator Travel Award American Heart Association, ATVB, 2015 ACCF/William F. Keating Award for Hypertension & Peripheral Vascular Disease 2013 Thomas W. Smith Fellowship Award BWH Cardiovascular Division, 2012 CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013 ATVB Travel Award for Young Investigators 2011 LCIC/Merck Future Leaders in CV Medical Research Grant 2010 Laennec Young Clinician Award Finalist American Heart Association, 2009 James Tolbert Shipley Prize for Research Harvard Medical School, 2005 Tau Beta Pi award for Excellence in Engineering 1997 Phi Beta Kappa Harvard College, 1996 Detur Prize Harvard College, 1994 National Merit Scholar 1993 Illinois All-State Academic Team 1993 Join now to see all Publications & Presentations PubMed
3 citationsThe impact of lipid-lowering medications on coronary artery plaque characteristics
Vishnu Priya Pulipati, Francis J. Alenghat> ;American Journal of Preventive Cardiology. 2021 Dec 1 5 citationsImproved Prognostic Performance of Cardiac Power Output with Right Atrial Pressure: A Sub-Analysis of the ESCAPE Trial.
Mark N. Belkin, Francis J. Alenghat, Stephanie A. Besser, Sean Pinney, Jonathan Grinstein> ;Journal of Cardiac Failure. 2021 Nov 10 1 citationsATTR Cardiomyopathy Meets Multiple Myeloma: The Importance of Cardiac Biopsy
Anthony J. Kanelidis, Patrick Miller, Nicole Prabhu, Mark Joshua Dela Cruz, Francis J. Alenghat, Phillip McMullen, Nitasha Sarswat, Benjamin A. Derman, Tamar S. Polons...> ;JACC. Cardiooncology. 2021 Oct 1 2 citationsA composite metric for predicting benefit from spironolactone in heart failure with preserved ejection fraction.
Mark N. Belkin, John E.A. Blair, Sanjiv J. Shah, Francis J. Alenghat> ;ESC Heart Failure. 2021 Aug 8 7 citationsRapid Exclusion of COVID Infection With the Artificial Intelligence Electrocardiogram.
Zachi I. Attia, Suraj Kapa, Jennifer L. Dugan, Naveen L. Pereira, Peter A. Noseworthy, Francisco Lopez Jimenez, Jessica Cruz, Rickey E. Carter, Daniel C. DeSimone, Joh...> ;Mayo Clinic Proceedings. 2021 Aug 31 Comparison of semi-automated versus manual quantitative right ventricular assessment in tetralogy of Fallot.
Joanna Lowisz, Francis J. Alenghat, Yi Li, David A. Roberson, Jamie Penk, Rupali Gandhi> ;Cardiology in the Young. 2021 Mar 9 8 citationsAortic pulsatility index predicts clinical outcomes in heart failure: a sub-analysis of the ESCAPE trial.
Mark N. Belkin, Francis J. Alenghat, Stephanie A. Besser, Ann B. Nguyen, Ben B. Chung, Bryan Smith, Sara Kalantari, Nitasha Sarswat, John E.A. Blair, Gene Kim, Sean Pi...> ;ESC Heart Failure. 2021 Feb 17 72 citationsRIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-κB Activation and Atherogenesis in Mice.
Denuja Karunakaran, My-Anh Nguyen, Michele Geoffrion, Dianne Vreeken, Zachary Lister, Henry S. Cheng, Nicola Otte, Patricia Essebier, Hailey Wyatt, Joshua W. Kandiah, ...> ;Circulation. 2021 Jan 12 9 citationsDonor-derived cell-free DNA is associated with cardiac allograft vasculopathy.
Luise Holzhauser, Kevin J. Clerkin, T. Fujino, Francis J. Alenghat, Jayant Raikhelkar, Gene Kim, Gabriel Sayer, Nir Uriel> ;Clinical Transplantation. 2021 Feb 6 13 citationsHigh sensitivity Troponin-T for prediction of adverse events in patients with COVID-19.
Nandita Singh, Rajeev Anchan, Stephanie A. Besser, Mark N. Belkin, Mark Joshua Dela Cruz, Linda Lee, Dongbo Yu, Natasha Mehta, Ann B. Nguyen, Francis J. Alenghat> ;Biomarkers. 2020 Sep 26 11 citationsMonocyte and Macrophage Subtypes as Paired Cell Biomarkers for Coronary Artery Disease
Kathryn A. Arnold, John E.A. Blair, Jonathan Paul, Atman P. Shah, Sandeep Nathan, Francis J. Alenghat> ;Experimental Physiology. 2019 Sep 1 6 citationsCatheter Ablation for Atrial Fibrillation in 2019.
Gaurav A. Upadhyay, Francis J. Alenghat> ;JAMA. 2019 Aug 20 1 citationsThe SPRINT Trial Score web calculator
Luke J. Laffin, Francis J. Alenghat> ;European Journal of Preventive Cardiology. 2019 Jun 12 3 citationsAssociation of Atherosclerosis Prevalence With Age, Race, and Traditional Risk Factors in Patients With Psoriasis.
Kathryn A. Arnold, Alison D. Treister, Peter A. Lio, Francis J. Alenghat> ;JAMA Dermatology. 2019 May 1 9 citationsA data-zone scoring system to assess the generalizability of clinical trial results to individual patients
Luke J. Laffin, Stephanie A. Besser, Francis J. Alenghat> ;European Journal of Preventive Cardiology. 2019 Apr 1 20 citationsManagement of Blood Cholesterol.
Francis J. Alenghat, Andrew M. Davis> ;JAMA. 2019 Feb 26 16 citationsProtein Mimetic and Anticancer Properties of Monocyte-Targeting Peptide Amphiphile Micelles
Christopher Poon, Sampreeti Chowdhuri, Cheng Hsiang Kuo, Yun Fang, Francis J. Alenghat, Danielle Hyatt, Kian Kani, Mitchell E. Gross, Eun Ji Chung> ;ACS Biomaterials Science & Engineering. 2017 Oct 16 27 citationsThe Prevalence of Atherosclerosis in Those with Inflammatory Connective Tissue Disease by Race, Age, and Traditional Risk Factors
Francis J. Alenghat> ;Scientific Reports. 2016 Feb 4 Cardiovascular disease: monocyte-targeting supramolecular micellar assemblies: a molecular diagnostic tool for atherosclerosis (adv. Healthcare mater. 3/2015).
Chung, E. J.,Mlinar, L. B.,Nord, K.,Sugimoto, M. J.,Wonder, E.,Alenghat, F. J.,Fang, Y.,Tirrell, M.> ;Adv Healthc Mater. 2015 Feb 24 40 citationsMonocyte-Targeting Supramolecular Micellar Assemblies: A Molecular Diagnostic Tool for Atherosclerosis
Eun Ji Chung, Laurie B. Mlinar, Kathryn Nord, Matthew J. Sugimoto, Emily Wonder, Francis J. Alenghat, Yun Fang, Matthew Tirrell> ;Advanced Healthcare Materials. 2015 Feb 1 38 citationsMembrane protein dynamics and functional implications in mammalian cells.
Francis J. Alenghat, David E. Golan> ;Current Topics in Membranes. 2013 Jan 1 43 citationsMacrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement
Francis J. Alenghat, Quentin J. Baca, Nooreen Rubin, Lily I. Pao, Takashi Matozaki, Clifford A. Lowell, David E. Golan, Benjamin G. Neel, Kenneth D. Swanson> ;Journal of Cell Science. 2012 Nov 15 3 citationsGiant left ventricular aneurysm as a late complication of inferior myocardial infarction
Francis J. Alenghat, Gregory S. Couper, Michael M. Givertz> ;European Heart Journal. 2013 Feb 1 44 citationsMechanical control of cAMP signaling through integrins is mediated by the heterotrimeric Gαs protein
Francis J. Alenghat, Jessica D. Tytell, Charles K. Thodeti, Alexandrine Derrien, Donald E. Ingber> ;Journal of Cellular Biochemistry. 2009 Mar 1 137 citationsLoss of polycystin-1 in human cyst-lining epithelia leads to ciliary dysfunction.
Surya M. Nauli, Sandro Rossetti, Robert J. Kolb, Francis J. Alenghat, Mark B. Consugar, Peter C. Harris, Donald E. Ingber, Mahmoud Loghman-Adham, Jing Zhou> ;Journal of the American Society of Nephrology. 2006 Apr 1 Join now to see all Lectures
Inflammation and Atherosclerotic Cardiovascular Disease
Medical College of Wisconsin, Cardiology Grand Rounds - 12/2018 Chicago Biomedical Consortium Vascular Biology Exploratory Workshop
6/1/2014 gCV Research Seminar, University of Chicago
Chicago, IL - 11/1/2013 VA Boston Healthcare System Cardiology Grand Rounds
Boston, MA - 12/1/2012 University of Chicago Cardiology Grand Rounds
Chicago, IL - 11/1/2012 Brigham & Women’s Vascular Research Division Seminar
Boston, MA - 6/1/2011 Brigham & Women’s Cardiovascular Division Grand Rounds
Boston, MA - 6/1/2010 American Heart Association Scientific Sessions
Orlando, FL - 11/1/2009 Brigham & Women’s Hosp. Pathology Conf
Boston, MA - 10/1/2003 Howard Hughes Medical Institute Conference
Bethesda, MD - 9/1/2003 NASA Cell Science Conference
Houston, TX - 3/1/2001 Biophysics Program Seminar
Boston, MA - 2/1/2001 Children’s Hospital Surgical Research Seminar
Boston, MA - 1/1/2001 Join now to see all Press Mentions African American Patients with Psoriasis at Even Greater Risk of Atherosclerotic Heart Disease March 4th, 2019
Young Black Athletes Die of Hypertrophic Cardiomyopathy More Than Others July 1st, 2016
Connective Tissue Disease Increases Risk for Cardiovascular Problems February 5th, 2016
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