ImreNothMD

Pulmonology • Charlottesville, VA

Critical Care Medicine, Interstitial Lung Diseases, Pleural Disease

Professor of Medicine

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Office
1215 Lee St
Fl 8
Charlottesville, VA 22908
Phone+1 434-295-1000

Fax+1 434-972-4266
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Education & Training

University of ChicagoFellowship, Pulmonary Disease and Critical Care Medicine, 1996 - 1999
University of California Davis HealthResidency, Internal Medicine, 1992 - 1995
University of Arizona College of MedicineClass of 1992

Certifications & Licensure

AZ State Medical License 1995 - Present
CA State Medical License 1993 - Present
VA State Medical License 2018 - 2026
IL State Medical License 1996 - 2020
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Clinical Trials

A Pilot Study of the Mechanism of Synergism Between FP and Salmeterol in Preventing COPD Exacerbations Start of enrollment: 2005 Jan 01
Completed
Phase 1
A Study of the Natural Progression of Interstitial Lung Disease (ILD) Start of enrollment: 2005 Sep 01
Recruiting
Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis Start of enrollment: 2007 Aug 01
Completed
Phase 3
Evaluating the Effectiveness of Prednisone, Azathioprine, and N-acetylcysteine in Patients With IPF Start of enrollment: 2009 Oct 01
Completed
Phase 3
AntiCoagulant Effectiveness in Idiopathic Pulmonary Fibrosis Start of enrollment: 2009 Oct 01
Terminated
Phase 3
STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF) Start of enrollment: 2012 Jul 16
Completed
Phase 2
Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry Start of enrollment: 2014 Jun 01
Recruiting
Treatment of IPF With Laparoscopic Anti-Reflux Surgery Start of enrollment: 2013 Dec 01
Completed
Not Applicable
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Publications & Presentations

PubMed

Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine.
Ayodeji Adegunsoye, Jonathan A Kropski, Juergen Behr, Timothy S Blackwell, Tamera J Corte, Vincent Cottin, Allan Glanville, Marilyn K Glassberg, Matthias Griese, Gary ...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Apr 4
A multidimensional classifier to support lung transplant referral in patients with pulmonary fibrosis.
Shwu-Fan Ma, Angela L Linderholm, Ching-Hsien Chen, Daniel F Dilling, Timothy P M Whelan, Fernando J Martinez, John S Kim, Michael P Combs, Ayodeji Adegunsoye, Mary E ...> ;The Journal of Heart and Lung Transplantation. 2024 Mar 29
Meaningful Endpoints for Idiopathic Pulmonary Fibrosis (IPF) Clinical Trials: Emphasis on 'Feels, Functions, Survives'. Report of a Collaborative Discussion in a Sympo...
Ganesh Raghu, Marya Ghazipura, Thomas R Fleming, Kerri I Aronson, Jürgen Behr, Kevin K Brown, Kevin R Flaherty, Ella A Kazerooni, Toby M Maher, Luca Richeldi, Joseph A...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Mar 15
The Role of Inflammation and Fibrosis in ILD Treatment Decisions.
Juergen Behr, Margaret L Salisbury, Simon L F Walsh, Anna J Podolanczuk, Lida P Hariri, Gary M Hunninghake, Martin Kolb, Christopher J Ryerson, Vincent Cottin, Mary B ...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Mar 14
Machine Learning of Plasma Proteomics Classifies Diagnosis of Interstitial Lung Disease.
Yong Huang, Shwu-Fan Ma, Justin M Oldham, Ayodeji Adegunsoye, Daisy Zhu, Susan Murray, John S Kim, Catherine Bonham, Emma Strickland, Angela L Linderholm, Cathryn T Le...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Feb 29
Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men.
Wu, P., Van Scoyk, M., McHale, S., Chou, C., Riddick, G., Farouq, K., Hu, B., Kraskauskiene, V., Koblinski, J., Lyons, C., Rijal, A., Vudatha, V., Zhang, D., Trevino, ...> ;Iscience. 2024 Feb 16
Reply to: Leveraging Microbiome Composition Variability for Precision Medicine in Idiopathic Pulmonary Fibrosis.
David O'Dwyer, Imre Noth, Justin M Oldham> ;American Journal of Respiratory and Critical Care Medicine. 2024 Jan 25
Genome-wide SNP-sex interaction analysis of susceptibility to idiopathic pulmonary fibrosis.
Kaminski, N., Olivia C Leavy, Anne F Goemans, Amy D Stockwell, Richard J Allen, Beatriz Guillen-Guio, Tamara Hernandez-Beeftink, Ayodeji Adegunsoye, Helen L Booth, , P...> ;Medrxiv. 2024 Jan 15
Association study of human leukocyte antigen variants and idiopathic pulmonary fibrosis.
Kaminski, N., Beatriz Guillen-Guio, Megan L Paynton, Richard J Allen, Daniel P W Chin, Lauren J Donoghue, Amy Stockwell, Olivia C Leavy, Tamara Hernandez-Beeftink, Car...> ;ERJ Open Research. 2024 Jan 1
Commensal Oral Microbiota, Disease Severity and Mortality in Fibrotic Lung Disease.
O'Dwyer, D., Kim, J., Ma, S., Ranjan, P., Das, P., Lipinski, J., Metcalf, J., Falkowski, N., Yow, E., Anstrom, K., Dickson, R., Huang, Y., Gilbert, J., Martinez, F., N...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Dec 5
Gastro-oesophageal reflux and idiopathic pulmonary fibrosis: sorting the chicken and the egg by genetic link.
Chad A Newton, Imre Noth, Ganesh Raghu> ;The European Respiratory Journal. 2023 Dec 1
Comparison of Pirfenidone and Nintedanib: Post Hoc Analysis of the CleanUP-IPF Study.
John S Kim, Susan Murray, Eric Yow, Hyun J Kim, Kevin R Flaherty, Fernando J Martinez, Imre Noth, Kevin J Anstrom> ;Chest. 2023 Nov 27
1 citations
Associations of Plasma Omega-3 Fatty Acids With Progression and Survival in Pulmonary Fibrosis.
John S Kim, Shwu-Fan Ma, Jennie Z Ma, Yong Huang, Catherine A Bonham, Justin M Oldham, Ayodeji Adegunsoye, Mary E Strek, Kevin R Flaherty, Emma Strickland, Inemesit Ud...> ;Chest. 2024 Mar 1
Proteomic Biomarkers of Survival in Idiopathic Pulmonary Fibrosis.
Justin M Oldham, Yong Huang, Swaraj Bose, Shwu-Fan Ma, John S Kim, Alexandra Schwab, Christopher Ting, Kaniz Mou, Cathryn T Lee, Ayodeji Adegunsoye, Sahand Ghodrati, J...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Oct 17
1 citations
Approach to Clinical Trials for the Prevention of Pulmonary Fibrosis.
John S Kim, Sydney B Montesi, Ayodeji Adegunsoye, Stephen M Humphries, Margaret L Salisbury, Lida P Hariri, Jonathan A Kropski, Luca Richeldi, Athol U Wells, Simon Wal...> ;Annals of the American Thoracic Society. 2023 Dec 1
The Intensive Care Unit Bundle Board: A Novel Real-Time Data Visualization Tool to Improve Maintenance Care for Invasive Catheters.
Claire Leilani Davis, Margot Bjoring, Jordyn Hursh, Samuel Smith, Cheri Blevins, Kris Blackstone, Evie Nicholson, Tracey Hoke, Jonathan Michel, Imre Noth, Andrew Barro...> ;Applied Clinical Informatics. 2023 Oct 1
4 citations
Telomere length and immunosuppression in non-idiopathic pulmonary fibrosis interstitial lung disease.
David Zhang, Ayodeji Adegunsoye, Julia Kozlitina, Nicole Garcia, Maria Poonawalla, Rachel Strykowski, Angela L Linderholm, Brett Ley, Shwu-Fan Ma, Imre Noth, Mary E St...> ;The European Respiratory Journal. 2023 Nov 1
Association study of human leukocyte antigen (HLA) variants and idiopathic pulmonary fibrosis.
Kaminski, N., Guillen-Guio, B., Paynton, M., Allen, R., Chin, D., Donoghue, L., Stockwell, A., Leavy, O., Hernandez-Beeftink, T., Reynolds, C., Cullinan, P., Martinez,...> ;Medrxiv. 2023 Jul 24
13 citations
PCSK6 and Survival in Idiopathic Pulmonary Fibrosis.
Kaminski, N., Justin M Oldham, Richard J Allen, Jose M Lorenzo-Salazar, Philip L Molyneaux, Shwu-Fan Ma, Chitra Joseph, John S Kim, Beatriz Guillen-Guio, Tamara Hernán...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Jun 1
5 citations
Integrative multi-omics analysis reveals novel idiopathic pulmonary fibrosis endotypes associated with disease progression.
Peifeng Ruan, Jamie L Todd, Hongyu Zhao, Yi Liu, Richard Vinisko, Julia F Soellner, Ramona Schmid, Robert J Kaner, Tracy R Luckhardt, Megan L Neely, Imre Noth, Mary Po...> ;Respiratory Research. 2023 May 31
Antigenic responses are hallmarks of fibrotic interstitial lung diseases independent of underlying etiologies.
Young Me Yoon, Tania E Velez, Vaibhav Upadhyay, Sara E Vazquez, Cathryn T Lee, Kavitha C Selvan, Christopher S Law, Kelly M Blaine, Maile K Hollinger, Donna C Decker, ...> ;Medrxiv. 2023 May 11
19 citations
The causal relationship between gastro-oesophageal reflux disease and idiopathic pulmonary fibrosis: a bidirectional two-sample Mendelian randomisation study.
Carl J Reynolds, Fabiola Del Greco M, Richard J Allen, Carlos Flores, R Gisli Jenkins, Toby M Maher, Philip L Molyneaux, Imre Noth, Louise V Wain, Jiyuan An, Jue-Sheng...> ;The European Respiratory Journal. 2023 May 1
7 citations
Telomere length associates with chronological age and mortality across racially diverse pulmonary fibrosis cohorts.
Ayodeji Adegunsoye, Chad A Newton, Justin M Oldham, Brett Ley, Cathryn T Lee, Angela L Linderholm, Jonathan H Chung, Nicole Garcia, Da Zhang, Rekha Vij, Robert Guzy, R...> ;Nature Communications. 2023 Mar 17
Reply to Spek and Duitman.
Justin M Oldham, Richard J Allen, Jose M Lorenzo-Salazar, Carlos Flores, Louise V Wain, Imre Noth> ;American Journal of Respiratory and Critical Care Medicine. 2023 Jun 15
Central lung gene expression associates with myofibroblast features in idiopathic pulmonary fibrosis.
Yong Huang, Rob Guzy, Shwu-Fan Ma, Catherine A Bonham, Jonathan Jou, Jefree J Schulte, John S Kim, Andrew J Barros, Milena S Espindola, Aliya N Husain, Cory M Hogaboam...> ;BMJ Open Respiratory Research. 2023 Feb 1
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Other

Management of the patient with severe COPD and cardiovascular disease
Noth I, Schmidt GA
http://www.uptodate.com/contents/management-of-the-patient-with-severe-copd-and-cardiovascular-disea
UpToDate, Wolters Kluwer Health - 2013-02-12

Press Mentions

Antibiotics Won't Help Fight Lung-Scarring Disease IDF: StudyJune 4th, 2021
Ofev Doubles the Chance of Improving or Stabilizing IPFMay 26th, 2017
37% of Pulmonary Fibrosis Patients Treated with Ofev Maintained Lung Function, Presentation ShowedMay 25th, 2017
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Grant Support

Genome-Wide Association And EXON Sequencing Study In IPFNational Heart, Lung, And Blood Institute2009–2010
Combination Therapy In IPFNational Heart, Lung, And Blood Institute2005–2009
FP And Salmeterol In Preventing COPD ExacerbationsNational Center For Research Resources2006–2007