IraSethWinerMDPhD

PubMed

• A phase 1b open-label study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of py314 in combination with pembrolizumab in patients with ad...
  Kathryn E Beckermann, Amita Patnaik, Ira Winer, Winston Tan, Babar Bashir, Christos E Kyriakopoulos, Randy F Sweis, Marc Chamberlain, Brian I Rini> ;Investigational New Drugs. 2024 Apr 1
• Ezabenlimab (BI 754091), an anti-PD-1 antibody, in patients with advanced solid tumours.
  Melissa Johnson, Hendrik-Tobias Arkenau, Natalie Cook, Vanessa Samouëlian, Shigehisa Kitano, Christine Duffy, Miaomiao Ge, Mabrouk Elgadi, Lillian L Siu, Manish R Pate...> ;Cancer Immunology, Immunotherapy. 2024 Mar 30
• Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study.
  Ayse Bahar Ercan, Melyssa Aronson, Nicholas R Fernandez, Yuan Chang, Adrian Levine, Zhihui Amy Liu, Logine Negm, Melissa Edwards, Vanessa Bianchi, Lucie Stengs, Jiil C...> ;The Lancet. Oncology. 2024 Mar 26
• HER2+ endometrioid endometrial cancer possesses distinct molecular and immunologic features associated with a more active immune microenvironment and worse prognosis.
  Shaina F Bruce, Sharon Wu, Jennifer R Ribeiro, Alex Farrell, Matthew J Oberley, Ira Winer, Britt K Erickson, Tenley Klc, Nathaniel L Jones, Premal H Thaker, Matthew A ...> ;Gynecologic Oncology. 2023 May 1
• 27 citations
  A Phase III Study of Pafolacianine Injection (OTL38) for Intraoperative Imaging of Folate Receptor-Positive Ovarian Cancer (Study 006).
  Janos L Tanyi, Leslie M Randall, Setsuko K Chambers, Kristina A Butler, Ira S Winer, Carrie L Langstraat, Ernest S Han, Alexander L Vahrmeijer, Hye Sook Chon, Mark A M...> ;Journal of Clinical Oncology. 2023 Jan 10
• 2 citations
  Molecular portraits of clear cell ovarian and endometrial carcinoma with comparison to clear cell renal cell carcinoma.
  Sarah A Ackroyd, David Arguello, Pilar Ramos, Haider Mahdi, Adam ElNaggar, Ira Winer, Rob Holloway, Thomas Krivak, Nathaniel Jones, Valerie Galvan Turner, Thomas Herzo...> ;Gynecologic Oncology. 2023 Feb 1
• 8 citations
  Genomic profiling in low grade serous ovarian cancer: Identification of novel markers for disease diagnosis and therapy.
  Adam ElNaggar, David Robins, Yasmine Baca, David Arguello, Michael Ulm, Rebecca Arend, Gina Mantia-Smaldone, Christina Chu, Ira Winer, Rob Holloway, Tom Krivak, Nathan...> ;Gynecologic Oncology. 2022 Nov 1
• 4 citations
  HER2 in Uterine Serous Carcinoma: Testing platforms and implications for targeted therapy.
  Tenley R Klc, Sharon Wu, Annelise M Wilhite, Nathaniel L Jones, Matthew A Powell, Alex Olawaiye, Eugenia Girda, Jubilee Brown, Allison Puechl, Rouba Ali-Fehmi, Ira S W...> ;Gynecologic Oncology. 2022 Nov 1
• 9 citations
  Molecular profiles of endometrial cancer tumors among Black patients.
  Annelise M Wilhite, Yasmine Baca, Joanne Xiu, Rajesh Paladugu, Adam C ElNaggar, Jubilee Brown, Ira S Winer, Robert Morris, Britt K Erickson, Alexander B Olawaiye, Matt...> ;Gynecologic Oncology. 2022 Jul 1
• 1 citations
  Incidence and Survival of Multiple Primary Cancers in US Women With a Gynecologic Cancer.
  Logan Corey, Julie Ruterbusch, Ron Shore, Martins Ayoola-Adeola, Michael Baracy, Alex Vezina, Ira Winer> ;Frontiers in Oncology. 2022 Jan 1
• 11 citations
  Disparities in Adjuvant Treatment of High-Grade Endometrial Cancer in the Medicare Population
  Logan Corey, Michele L. Cote, Julie J. Ruterbusch, Ira Winer> ;American Journal of Obstetrics and Gynecology. 2021 Nov 1
• 9 citations
  Assessment of immune biomarkers and establishing a triple negative phenotype in gynecologic cancers.
  G. Contos, Yasmine Baca, Joanne Xiu, Jennifer Brown, Robert W. Holloway, W.M. Korn, Thomas J. Herzog, N.L. Jones, Ira Winer> ;Gynecologic Oncology. 2021 Nov 1
• Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer.
  Colombo N, Dubot C, Lorusso D, Caceres MV, Hasegawa K, Shapira-Frommer R, Tewari KS, Salman P, Hoyos Usta E, Yañez E, Gümüş M, Olivera Hurtado de Mendoza M, Samouëlian...> ;The New England journal of medicine. 2021-09-18
• 21 citations
  Neuroendocrine tumors of the gynecologic tract update.
  Ira Winer, C. Kim, Paola A. Gehrig> ;Gynecologic Oncology. 2021 May 19
• 25 citations
  Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance.
  Carol Durno, Ayse Bahar Ercan, Vanessa Bianchi, Melissa Edwards, Melyssa Aronson, Melissa Galati, Eshetu G. Atenafu, Gadi Abebe-Campino, Abeer Al-Battashi, Musa Alharb...> ;Journal of Clinical Oncology. 2021 May 4
• 4 citations
  ONC201 induces the unfolded protein response (UPR) in high- and low-grade ovarian carcinoma cell lines and leads to cell death regardless of platinum sensitivity.
  Marufa Rumman, Steven Buck, Lisa Polin, Sijana H. Dzinic, Julie L. Boerner, Ira Winer> ;Cancer Medicine. 2021 May 1
• 7 citations
  Hysteroscopic Morcellation in Endometrial Cancer Diagnosis: Increased Risk?
  Rebeca Kelly, George Contos, Christopher Walker, Martins Ayoola-Adeola, Seongho Kim, Ira Winer> ;Journal of Minimally Invasive Gynecology. 2021 Feb 8
• 5 citations
  Dual-Illumination Ultrasound/ Photoacoustic System for Cervical Cancer Imaging
  Maryam Basij, Andrei Karpiouk, Ira Winer, Stanislav Emelianov, Mohammad Mehrmohammadi> ;IEEE Photonics Journal. 2021 Feb 1
• 4 citations
  The Landscape of Glycogen Synthase Kinase-3 Beta Genomic Alterations in Cancer
  Brittany A. Borden, Yasmine Baca, Joanne Xiu, Fabio Tavora, Ira Winer, Benjamin A. Weinberg, Ari M. Vanderwalde, Sourat Darabi, W. Michael Korn, Andrew P. Mazar, Franc...> ;Molecular Cancer Therapeutics. 2021 Jan 1
• 11 citations
  Tumor-associated macrophages derived from cancer stem cells
  Amira Osman, Miharu Oze, Said M. Afify, Ghmkin Hassan, Samah El-Ghlban, Hend M. Nawara, Xiaoying Fu, Maram H. Zahra, Akimasa Seno, Ira Winer, David S. Salomon, Masahar...> ;Acta Histochemica. 2020 Dec 31
• 21 citations
  Prognostic value of changes in neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and lymphocyte-to-monocyte ratio (LMR) for patients with cervic...
  Hamilton Trinh, Stephen P. Dzul, Jalal Hyder, Hyejeong Jang, Seongho Kim, Julianne Flowers, Nitin Vaishampayan, Jerry Chen, Ira Winer, Steven Miller> ;Clinica Chimica Acta; International Journal of Clinical Chemistry. 2020 Nov 1
• 109 citations
  Berzosertib plus gemcitabine versus gemcitabine alone in platinum-resistant high-grade serous ovarian cancer: a multicentre, open-label, randomised, phase 2 trial.
  Panagiotis A. Konstantinopoulos, Su Chun Cheng, Andrea E. Wahner Hendrickson, Richard T. Penson, Susan Schumer, L. Austin Doyle, Elizabeth K. Lee, Elise C. Kohn, Linda...> ;The Lancet. Oncology. 2020 Jun 15
• 30 citations
  Comparative Analysis of Differentially Expressed miRNAs and their Downstream mRNAs in Ovarian Cancer and its Associated Endometriosis
  Richard Licheng Wu, Shadan Ali, Sudeshna Bandyopadhyay, Baraa Alosh, Kinda Hayek, Mhd Fayez Daaboul, Ira Winer, Fazlul H. Sarkar, Rouba Ali-Fehmi> ;Journal of Cancer Science & Therapy. 2015 Jan 1
• 25 citations
  Miniaturized phased-array ultrasound and photoacoustic endoscopic imaging system.
  Maryam Basij, Yan Yan, Suhail Alshahrani, Hamid Helmi, Timothy K. Burton, Jay Burmeister, Michael M. Dominello, Ira Winer, Mohammad Mehrmohammadi> ;Photoacoustics. 2019 Jul 25
• 8 citations
  Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance
  Batoul Farran, Samet Albayrak, Judith Abrams, Michael A. Tainsky, Nancy Levin, Robert T. Morris, Larry H. Matherly, Manohar Ratnam, Ira Winer> ;Cancer Medicine. 2019 Mar 1
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Journal Articles

• Merkel cell carcinoma in a patient with noninvasive vulvar Paget's disease  
  Winer IS, Lonardo F, Johnson SC, Deppe G., Am J Obstet Gynecol, 3/30/2013
• Chemotherapy of vulvar cancer: A Review  
  Deppe G, Mert I, Belotte J, WinerIS, Wien KlinWochenschr, 3/1/2013
• Clinical and Pathologic Characteristics of Serous Carcinoma Confined to the Endometrium: A Multi-institutional Study  
  Seeman A, Mert I, Munkarah A, Bandyopadhyay S, Winer I, et al., Int J GynecolPathol, 3/1/2013
• Correlation of tumor size with other prognostic factors in uterine serous carcinoma: A large multi-institutional study  
  Winer IS, Mahdi HS, Bandyopadhyay S, et al., GynecolOncol, 2/1/2013
• F3-Targeted Cisplatin-Hydrogel Nanoparticles as an Effective Therapeutic that Targets Both Murine and Human Ovarian Tumor Endothelial Cells In vivo  
  Winer I, Wang S, Lee Y-E, Fan W, Gong Y, Buros-Ojeda D, Spahlinger G, Kopelman, Buckanovich RJ, Cancer Res., 11/1/2010
• A case of progressive mucinous ovarian cancer of low malignant potential responsive to biologic therapy with Bevacizumab  
  Winer I, Buckanovich RJ, Gynecol Oncol, 3/1/2010
• Bevacizumab for the Treatment of Non-ResectablePseudomyxomaperitonei Associated with Mucinous Ovarian Tumor of Low Malignant Potential – A Comparison of Two Cases  
  Winer I, Buckanovich RJ, Case Rep Oncol, 1/1/2010
• Effective Expression of Small Interfering RNA in human cells  
  Paul C, Good P, Winer I, Engelke DR, Nature Biotechnology, 1/1/2009
• Drosophila split ends homologue SHARP functions as a positive regulator of Wnt/beta-catenin/T-cell factor signaling in neoplastic transformation  
  ChoKR,Fearon ER, Cancer Res., 1/15/2007
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  Winer I, Gonik, N., Fearon, E.R, JBC, 1/1/2006
• Expression of 12-Lipoxygenase as a biomarker for Melanoma Carcinogenesis  
  Winer I, Normolle DP, Shureiqi I, Sondak VK, Johnson T, Su L, Brenner DE., Melanoma Research, 1/1/2002
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  Kolligs FT, Nieman M, Winer I, Hu G, Van Mater D, Feng Y, Smith I, Wu R, Zhai Y, Cho K, Fearon ER, Cancer Cell, 1/1/2002
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Books/Book Chapters

• Know Thy Place 
  Chapter: Jonathan Adams Allen 
  Winer IAnn Arbor: University of Michigan Press2000

Abstracts/Posters

• The significance of squamous vs. adenocarcinoma subtypes in early stage cervical carcinoma
  Winer I, Alvarado-Cabrero I, Seward S, Valencia-Cedillo R, Munkarah A, Ali-Fehmi R., American Association of Cancer Research Annual Meeting, 4/1/2013
• A multi-institutional clinic-pathologic study of USC without myometrial invasion
  Winer I, Semaan A,Mert I, Hayek K, Bandyopadhyay S, Nucci MR, Van de Vijver KK, Hussein Y, Alosh B, Oliva E, Ali-Fehmi R, International Gynecologic Cancer Society (IGCS),, 10/1/2012
• Activation of the unfolded protein response (UPR) by disulfiram in ovarian cancer cells: A novel therapeutic mechanism to overcome chemoresistance
  Winer et al., International Journal of Gynecological Cancer, 10/1/2012
• Histone deacetylase inhibition in ovarian cancer
  Winer et al., Gynecologic Oncology, 1/1/2008
• Vascular targeted cisplatin nanoparticles for ovarian cancer therapy
  Winer et al., Gynecologic Oncology, 1/1/2008
• 12-Lipoxygenase Expression in Human Pigmented Skin Neoplasia
  Winer et al., Proceedings of the American Association for Cancer Research, 1/1/2001
• Disufiram (Antabuse) Activates the Unfolded Protein Response to Overcome Chemoresistance in Ovarian Cancer Cells
  Winer et al., MSACOG Resident/Fellow Research Day
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