JeffreyLFineMD

PubMed

• Upgrade Rates of Variant Lobular Carcinoma In Situ Compared to Classic Lobular Carcinoma In Situ Diagnosed in Core Needle Biopsies: A 10-Year Single Institution Retros...
  Lakshmi Harinath, Tatiana M Villatoro, Beth Z Clark, Jeffrey L Fine, Jing Yu, Gloria J Carter, Emilia Diego, Priscilla F McAuliffe, Phuong Mai, Amy Lu, Margarita Zuley...> ;Modern Pathology. 2024 Apr 1
• Implementation of Digital Image Analysis in Assessment of Ki67 Index in Breast Cancer.
  Rachel K Vanderschelden, Daniel Gonzalez, Lindsey Seigh, Gloria J Carter, Beth Z Clark, Esther Elishaev, Jeffrey Louis Fine, Lakshmi Harinath, Mirka W Jones, Tatiana M...> ;Applied Immunohistochemistry & Molecular Morphology. 2024 Jan 1
• 1 citations
  Clinicopathologic and genomic features of lobular like invasive mammary carcinoma: is it a distinct entity?
  Jing Yu, Edaise M da Silva, Hae-Sun La, Beth Z Clark, Jeffrey L Fine, Gloria J Carter, Tatiana M Villatoro, T Rinda Soong, Adrian V Lee, Steffi Oesterreich, Thais Basi...> ;NPJ Breast Cancer. 2023 Jul 13
• 1 citations
  Utility of TRPS1 immunohistochemistry in confirming breast carcinoma: Emphasis on staining in triple-negative breast cancers and gynecologic tumors.
  Rayan Rammal, Kanika Goel, Esther Elishaev, T Rinda Soong, Mirka W Jones, Chengquan Zhao, Beth Z Clark, Gloria J Carter, Jing Yu, Jeffrey L Fine, Tatiana M Villatoro, ...> ;American Journal of Clinical Pathology. 2023 Oct 3
• Lining Up the Pieces: Coregistration of Digital Pathology Images Is an Underused Technique With Great Promise in Advancing Computational Pathology.
  Jeffrey L Fine> ;American Journal of Clinical Pathology. 2023 Mar 13
• 4 citations
  The Utility of SOX10 Immunohistochemical Staining in Breast Pathology.
  Rayan Rammal, Kanika Goel, Esther Elishaev, T Rinda Soong, Mirka W Jones, Chengquan Zhao, Beth Z Clark, Gloria J Carter, Jing Yu, Jeffrey L Fine, Tatiana M Villatoro, ...> ;American Journal of Clinical Pathology. 2022 Nov 3
• Prognostic Significance of Three-Tiered World Health Organization Classification of Phyllodes Tumor and Correlation to Singapore General Hospital Nomogram.
  Davsheen Bedi, Beth Z Clark, Gloria J Carter, Jing Yu, Jeffrey L Fine, Tatiana M Villatoro, Rohit Bhargava> ;American Journal of Clinical Pathology. 2022 Sep 2
• 6 citations
  Clinical-pathologic characteristics and response to neoadjuvant chemotherapy in triple-negative low Ki-67 proliferation (TNLP) breast cancers.
  Pooja Srivastava, Tiannan Wang, Beth Z Clark, Jing Yu, Jeffrey L Fine, Tatiana M Villatoro, Gloria J Carter, Adam M Brufsky, Vikram C Gorantla, Shannon L Huggins-Puhal...> ;NPJ Breast Cancer. 2022 Apr 20
• 29 citations
  Explainable AI (xAI) for Anatomic Pathology.
  Akif Burak Tosun, Filippo Pullara, Michael J. Becich, D. Lansing Taylor, Jeffrey L. Fine, Chakra Chennubhotla> ;Advances in Anatomic Pathology. 2020 Jul 1
• 30 citations
  Oncologic Safety of Fat Grafting for Autologous Breast Reconstruction in an Animal Model of Residual Breast Cancer.
  Mayara Mytzi de Aquino Silva, Lauren E. Kokai, Vera S. Donnenberg, Jeffrey L. Fine, Kacey G. Marra, Albert D. Donnenberg, Miguel Sabino Neto, J. Peter Rubin> ;Plastic and Reconstructive Surgery. 2019 Jan 1
• Advanced Imaging Techniques for the Pathologist
  Jeffrey L. Fine> ;Clinics in Laboratory Medicine. 2016 Mar 1
• 90 citations
  Key Residues Defining the Μ-Opioid Receptor Binding Pocket: A Site-Directed Mutagenesis Study
  Alfred Mansour, Larry P. Taylor, Jeffrey L. Fine, Robert C. Thompson, Mary T. Hoversten, Henry I. Mosberg, Stanley J. Watson, Huda Akil> ;Journal of Neurochemistry. 2002 Nov 18
• Educational Case: High-Grade Serous Carcinoma of the Ovary.
  Sophia G Bunde, Swikrity Upadhyay Baskota, Jeffrey L. Fine, Samer N. Khader> ;Academic Pathology. 2021 Aug 27
• 19 citations
  In Vivo and Ex Vivo Microscopy: Moving Toward the Integration of Optical Imaging Technologies Into Pathology Practice.
  Wendy A. Wells, Michael J. Thrall, Anastasia Sorokina, Jeffrey L. Fine, Savitri Krishnamurthy, Attiya Haroon, Babar Rao, Maria M. Shevchuk, Herbert C. Wolfsen, Guiller...> ;Archives of Pathology & Laboratory Medicine. 2019 Mar 1
• 4 citations
  Pathologists' Computer-Assisted Diagnosis: A Mock-up of a Prototype Information System to Facilitate Automation of Pathology Sign-out
  Navid Farahani, Zheng Liu, Dylan Jutt, Jeffrey L. Fine> ;Archives of Pathology & Laboratory Medicine. 2017 Jul 7
• Architectural patterns for differential diagnosis of proliferative breast lesions from histopathological images
  Luong Nguyen, Akif Burak Tosun, Jeffrey L. Fine, D L Taylor, S.C. Chennubhotla> ;Proceedings. IEEE International Symposium on Biomedical Imaging. 2017 Apr 18
• 11 citations
  Spatial Statistics for Segmenting Histological Structures in H&E Stained Tissue Images
  Luong Nguyen, Akif Burak Tosun, Jeffrey L. Fine, Adrian V. Lee, D. Lansing Taylor, Chakra Chennubhotla> ;IEEE Transactions on Medical Imaging. 2017 Mar 16
• 70 citations
  Functional interaction of histone deacetylase 5 (HDAC5) and lysine-specific demethylase 1 (LSD1) promotes breast cancer progression.
  Chunyu Cao, Shauna N. Vasilatos, Rohit Bhargava, Jeffrey L. Fine, Steffi Oesterreich, Nancy E. Davidson, Yi Fei Huang> ;Oncogene. 2017 Jan 5
• 28 citations
  Exploring virtual reality technology and the Oculus Rift for the examination of digital pathology slides
  Navid Farahani, Robert Post, Jon Duboy, Ishtiaque Ahmed, Brian J. Kolowitz, Teppituk Krinchai, Sara E. Monaco, Jeffrey L. Fine, Douglas J. Hartman, Liron Pantanowitz> ;Journal of Pathology Informatics. 2016 Jan 1
• 13 citations
  Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers.
  Daniel Spagnolo, Rekha Gyanchandani, Yousef Al-Kofahi, Andrew M. Stern, Timothy R. Lezon, Albert Gough, Dan E. Meyer, Fiona Ginty, Brion Daryl Sarachan, Jeffrey L. Fin...> ;Journal of Pathology Informatics. 2016 Jan 1
• 25 citations
  A Role for Histone H2B Variants in Endocrine-Resistant Breast Cancer
  Shweta Nayak, Emily Harrington, David N. Boone, Ryan J. Hartmaier, Jian Chen, Thushangi N. Pathiraja, Kristine L. Cooper, Jeffrey L. Fine, Joseph S. Sanfilippo, Nancy ...> ;Hormones & Cancer. 2015 Jun 26
• Advanced Imaging Techniques for the Pathologist.
  Jeffrey L. Fine> ;Surgical Pathology Clinics. 2015 Jun 1
• 13 citations
  21 st century workflow: A proposal
  Jeffrey L. Fine> ;Journal of Pathology Informatics. 2014 Jan 1
• 20 citations
  Imaging of Mohs Micrographic Surgery Sections Using Full‐Field Optical Coherence Tomography: A Pilot Study
  John R. Durkin, Jeffery L. Fine, Hakeem Sam, Melissa Pugliano-Mauro, Jonhan Ho> ;Dermatologic Surgery. 2014 Mar 1
• 88 citations
  Can digital pathology result in cost savings? A financial projection for digital pathology implementation at a large integrated health care organization
  Jonhan Ho, Stefan M Ahlers, Curtis Stratman, Orly Aridor, Liron Pantanowitz, Jeffrey L. Fine, John A Kuzmishin, Michael Christopher Montalto, Anil V. Parwani> ;Journal of Pathology Informatics. 2014 Jan 1
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Journal Articles

• A validation study of quantum dot multispectral imaging to evaluate hormone receptor status in ductal carcinoma in situ (DCIS) of the breast.  
  Yu J, Monaco SE, Onisko A, Bhargava R, Dabbs DJ, Cieply KM, Fine JL, Hum Pathol
• A natural language intelligent tutoring system for training pathologists: implementation and evaluation.  
  El Saadawi GM, Tseytlin E, Legowski E, Jukic D, Castine M, Fine J, Gormley R, Crowley RS, Adv Health Sci Educ Theory Pract
• Pattern of c-fos mRNA induction in rat brain by acute morphine.  
  Gutstein HB, Thome JL, Fine JL, Watson SJ, Akil H, Canadian Journal of Physiology and Pharmacology. 76(3):294-303
• Key residues defining the mu-opioid receptor binding pocket: a site-directed mutagenesis study.  
  Mansour A, Taylor LP, Fine JL, Thompson RC, Hoversten MT, Mosberg HI, Watson SJ, Akil H, Journal of Neurochemistry. 68(1):344-53
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Abstracts/Posters

• Preliminary Validation of a Multispectral Image Analysis Application for Confirmation of Isolated Tumor Cells in Axillary Lymph Nodes from Breast Cancer Patients.
  Fine JL, K McManus, A Luketich, Dabbs DJ, Advancing Practice, Instruction and Innovation Through Informatics (APIII), Pittsburgh
• HER2 Immunohistochemistry: Workflow Experience with Image Analysis Based Interpretation of CB11 and 4B5 Clones.
  Fine JL, Bhargava R, Surti U, Dabbs D, Advancing Practice, Instruction and Innovation Through Informatics (APIII), Pittsburgh
• Whole Slide Image Based Interpretation of Immunohistochemistry Stains in Challenging Prostate Needle Biopsies.
  Fine JL, Ho J, Yagi Y, Jukic D, Gilbertson JR, Bastacky SI, Grzybicki DM, Anthony L, Wilson R, Parwani AV, Advancing Practice, Instruction and Innovation Through Informatics (APIII), Vancouver
• XML-Based Virtual Slide Box for Teaching Histology and Pathology.
  Prayson R, Ermakov P, Henricks W, . Advancing Practice, Instruction, and Innovation Through Informatics (APIII), Pittsburgh
• Breast carcinoma Ki-67 labeling index: comparison between image analysis and expert human scoring with discussion about choosing which areas to analyze.
  Fine JL, Dabbs DJ, Cooper KL, Bhargava R, United States and Canadian Academy of Pathology, Vancouver
• Histopathologic correlation with spectral-domain optical coherence tomography (SD-OCT), a novel digital imaging technique.
  Smith MA, Kagemann L, Schuman JS, Fine JL, United States and Canadian Academy of Pathology, Vancouver
• Direct Digital Imaging of Breast Tissue Using Spectral-Domain Optical Coherence Tomography.
  Fine JL, Kagemann L, Wollstein G, Ishikawa H, Schuman JS, United States and Canadian Academy of Pathology, San Antonio
• HER2 immunohistochemistry: comparison of image analysis based interpretation of CB11 and 4B5 clones using reference fluorescence in-situ hybridization.
  Fine JL, Bhargava R, Surti U, Dabbs DJ, San Antonio Breast Symposium
• Whole Slide Images Used for Immunohistochemistry Stain Interpretation in Challenging Prostate Biopsies.
  Fine JL, Ho J, Jukic DM, Gilbertson JR, Bastacky SI, Anthony L, Wilson R, Epstein JI, Parwani AV, United States and Canadian Academy of Pathology, San Diego
• Evolution of Tele-neuropathology Intra-operative Consultation at an Academic Medical Center.
  Fine JL, Horbinski C, Medina-Flores R, Yagi Y, Wiley CA, Advancing Practice, Instruction and Innovation through Informatics (APIII), Vancouver
• Impact of Internet Based Resources on Resident Teaching and Educational Conferences: Experience at a University Affiliated Hospital Network Comprising Academic and Com...
  Fine JL, Yagi Y, Parwani AV, Becich MJ, Gilbertson JR, United States and Canadian Academy of Pathology, Atlanta
• Implementation of an electronic interface between an anatomic pathology laboratory information system and an automated immunohistochemistry system.
  Fine JL, Geisler WS, Willis-Eppinger GJ, Carter CC, Smith MB, Henricks, WH, Advancing Practice, Instruction and Innovation through Informatics (APIII), Lake Tahoe
• High-Throughput Automated Image Analysis of Multitarget Fluorescence In Situ Hybridization (FISH) Assay in Patients with Bladder Cancer and Atypical or Negative Urine ...
  Fine JL, Swain E, Tubbs RR, Pettay J, Hartke M, Keslar K, Simmerman K, Skacel M, United States and Canadian Academy of Pathology, San Antonio
• High-Throughput Image Analysis of HER2 Gene Amplification Detected by Second-Generation Gold-Facilitated Autometallographic Bright Field In-Situ Hybridization Assay (...
  Fine J, Downs-Kelly E, Hicks D, Pettay J, Tarr S, Ruddy T, Powell R, Mele J, Hainfeld J, Grogan T, Skacel M, Borthwick D, Tubbs R, United States and Canadian Academy of Pathology, Vancouver
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Lectures

• Advanced Imaging in Pathology: Optical Coherence Tomography (OCT). 
  Nationwide Digital Pathology Application and Development Conference, Kunming, China
• Microscopy in the 21st Century: Telepathology and Image Analysis (SP-75). 
  American Society for Clinical Pathology (ASCP) Annual Meeting, Chicago
• Practical Informatics Course (Beginners). 
  Advancing Practice, Instruction and Innovation through Informatics (APIII), Pittsburgh
• Practical Whole Slide Imaging Digital Pathology Workshop. 
  Advancing Practice, Instruction and Innovation through Informatics (APIII), Pittsburgh
• Whole Slide Image Validation Studies – Existing Research and Future Studies. 
  American Pathology Foundation Spring Conference. Scottsdale, AZ
• Progress towards Clinical Implementation of Automated Whole Slide Imaging: Whole Slide System Implementation. 
  Advancing Practice, Instruction and Innovation through Informatics (APIII), British Columbia
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