JohnMuraski, Jr.MDPhD(He/Him)

PubMed

• 24 citations
  De Novo Design of Skin-Penetrating Peptides for Enhanced Transdermal Delivery of Peptide Drugs
  Stefano Menegatti, Michael Zakrewsky, Sunny Kumar, Joshua Sanchez De Oliveira, John A. Muraski, Samir Mitragotri> ;Advanced Healthcare Materials. 2016 Mar 1
• 2 citations
  Enhanced epidermal localization of topically applied steroids using SPACE™ peptide.
  Sunny Kumar, Ming Chen, Aaron C. Anselmo, John A. Muraski, Samir Mitragotri> ;Drug Delivery and Translational Research. 2015 May 5
• 85 citations
  Peptides as skin penetration enhancers: mechanisms of action.
  Sunny Kumar, Michael Zakrewsky, Ming Chen, Stefano Menegatti, John A. Muraski, Samir Mitragotri> ;Journal of Controlled Release. 2015 Feb 10
• 32 citations
  Topical delivery of Cyclosporine A into the skin using SPACE-peptide.
  Ming Chen, Sunny Kumar, Aaron C. Anselmo, Vivek Gupta, Deborah H. Slee, John A. Muraski, Samir Mitragotri> ;Journal of Controlled Release. 2015 Feb 10
• 69 citations
  Topical delivery of siRNA into skin using SPACE-peptide carriers.
  Ming Chen, Michael Zakrewsky, Vivek Gupta, Aaron C. Anselmo, Deborah H. Slee, John A. Muraski, Samir Mitragotri> ;Journal of Controlled Release. 2014 Apr 10
• 75 citations
  Topical delivery of hyaluronic acid into skin using SPACE-peptide carriers.
  Ming Chen, Vivek Gupta, Aaron C. Anselmo, John A. Muraski, Samir Mitragotri> ;Journal of Controlled Release. 2014 Jan 10
• 73 citations
  Cardiac Progenitor Cell Cycling Stimulated by Pim-1 Kinase
  Christopher T. Cottage, Brandi Bailey, Kimberlee M. Fischer, Daniele Avitabile, Brett Collins, Savilla Tuck, Pearl Quijada, Natalie Gude, Roberto Alvarez, John A. Mura...> ;Circulation Research. 2010 Mar 19
• 59 citations
  Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload.
  John A. Muraski, Kimberlee M. Fischer, Weitao Wu, Christopher T. Cottage, Pearl Quijada, Matt Mason, Shabana Din, Natalie Gude, Roberto Alvarez, Marcello Rota, Jan Kaj...> ;Proceedings of the National Academy of Sciences of the United States of America. 2008 Sep 16
• 36 citations
  Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge.
  Sailay Siddiqi, Natalie Gude, Toru Hosoda, John A. Muraski, Marta Rubio, Gregory Emmanuel, Jenna Fransioli, Serena Vitale, Carola Eleonora Parolin, Domenico D'Amario, ...> ;Circulation Research. 2008 Jul 3
• 95 citations
  Evolution of the c-kit-Positive Cell Response to Pathological Challenge in the Myocardium
  Jenna Fransioli, Brandi Bailey, Natalie Gude, Christopher T. Cottage, John A. Muraski, Gregory Emmanuel, Weitao Wu, Roberto Alvarez, Marta Rubio, Sergio Ottolenghi, Er...> ;Stem Cells. 2008 May 1
• 152 citations
  Activation of Notch-Mediated Protective Signaling in the Myocardium
  Natalie Gude, Gregory Emmanuel, Weitao Wu, Christopher T. Cottage, Kimberlee M. Fischer, Pearl Quijada, John A. Muraski, Roberto Alvarez, Marta Rubio, Eric M. Schaefer...> ;Circulation Research. 2008 May 9
• 120 citations
  Formation of large coronary arteries by cardiac progenitor cells
  Jochen Tillmanns, Marcello Rota, Toru Hosoda, Yu Misao, Grazia Esposito, Arantxa Gonzalez, Serena Vitale, Carola Eleonora Parolin, Saori Yasuzawa-Amano, John A. Murask...> ;Proceedings of the National Academy of Sciences of the United States of America. 2008 Feb 5
• 195 citations
  Pim-1 regulates cardiomyocyte survival downstream of Akt
  John A. Muraski, Marcello Rota, Yu Misao, Jenna Fransioli, Christopher T. Cottage, Natalie Gude, Grazia Esposito, Francesca Delucchi, Michael L. Arcarese, Roberto Alva...> ;Nature Medicine. 2007 Dec 1
• 228 citations
  Bone marrow cells adopt the cardiomyogenic fate in vivo
  Marcello Rota, Jan Kajstura, Toru Hosoda, Claudia Bearzi, Serena Vitale, Grazia Esposito, Grazia Iaffaldano, M. Elena Padin-Iruegas, Arantxa Gonzalez, Roberto Rizzi, N...> ;Proceedings of the National Academy of Sciences of the United States of America. 2007 Nov 6
• 84 citations
  Akt Promotes Increased Cardiomyocyte Cycling and Expansion of the Cardiac Progenitor Cell Population
  Natalie Gude, John A. Muraski, Marta Rubio, Jan Kajstura, Erik Schaefer, Piero Anversa, Mark A. Sussman> ;Circulation Research. 2006 Aug 18
• 84 citations
  Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy
  Yasuyuki Tsujita, John A. Muraski, Isao Shiraishi, Takahiro Kato, Jan Kajstura, Piero Anversa, Mark A. Sussman> ;Proceedings of the National Academy of Sciences of the United States of America. 2006 Aug 8
• 135 citations
  Atrial natriuretic peptide promotes cardiomyocyte survival by cGMP-dependent nuclear accumulation of zyxin and Akt
  Takahiro Kato, John A. Muraski, Yan Chen, Yasuyuki Tsujita, Jason A. Wall, Christopher C. Glembotski, Erik Schaefer, Mary C. Beckerle, Mark A. Sussman> ;The Journal of Clinical Investigation. 2005 Oct 3
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Journal Articles

• Elderly Man with Abdominal Pain: ACE-inhibitor Induced Gastrointestinal Angioedema  
  Muraski JA, Emmanuel GN, Annals of Emergency Medicine, 6/2019
• Mechanistic analysis of cellular internalization of a cell and skin penetrating peptide.  
  Zakrewsky M, Muraski JA, Mitragotri S, Regenerative Engineering and Translational Medicine, 3/2016

Books/Book Chapters

• The Cardioprotective Effects of Pim-1 Kinase 
  Muraski JAUniversity of California San Diego, San DiegoEdition 1,2007

Abstracts/Posters

• Targeted nanoparticle-based therapy for the treatment of glioblastoma multiforme: Unprecedented anti-cancer activity in highly drug resistant/refractory mouse models o...
  6. Hudson S, Agemy L, Kotamraju VR, Sharma S, Ruoslahti E, Brunel F, MacLaren A, Muraski J, Slee D, AACR Annual Meeting 2014, San Diego, CA, 4/2014
• Pim-1 stimulates cardiac progenitor cell proliferation and asymmetric division.
  Cottage TC, Tuck S, Fischer K, Gude N, Muraski J, Sussman MA., American Heart Association, Scientific Sessions, New Orleans, LA, 11/2008
• Formation of temporary niches is required for bone marrow cells to adopt the cardiomyogenic fate in vivo
  Rota M, Kajstura J, Hosada T, Bearzi C, Vitale S, Esposito G, Iaffaldano G, Padin-Iruegas E, Gonzalez A, Rizzi R, Small N, Muraski J, Chan X, Urbanek K, Bolli R, House..., American Heart Association, Scientific Sessions, Melvin L. Marcus Young Investigator Award, Orlando, FL, 11/2007
• Activation of notch-mediated protective signaling in the myocardium
  Gude N, Emmanuel G, Wu W, Cottage CT, Fischer K, Quijada P, Muraski JA, Alvarez R, Rubio M, Schaefer E, Sussman MA, Keystone Symposium on Stem Cells, Keystone, CO, 7/2007
• Pim-1 regulates cardiomyocyte survival downstream of Akt
  Muraski JA, Fransioli J, Gude N, Alvarez R, Cottage C, Siddiqi S, Martindale J, Glembotski CC, Magnuson N, Berns A, Houser D, Schaefer E, Sussman MA, American Heart Association, Scientific Sessions;, Chicago, IL, 11/2006
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Lectures

• Altered mental status and tonic-clonic seizures in a patient after hip joint prosthesis explantation. 
  Clinical Neurology Continuing Medical Education Course, St. Vincent Medical Center - 11/13/2018
• 21st Century Drug Development: The SPACE peptide paradigm 
  College of Pharmacy, Department of Pharmacology & Toxicology, University of Arizona - 2/2015
• Convoy Therapeutics: a paradigm shift in transdermal drug delivery 
  White Hat Investors Forum, Phoenix, AZ - 10/2014
• Convoy Therapeutics: a paradigm shift in transdermal drug delivery 
  Rocky Mountain Life Sciences Investor and Partnering Conference, Vail, CO - 9/2014
• Convoy Therapeutics: a paradigm shift in transdermal drug delivery 
  Family Office and Investment Conference; Geneva, Switzerland - 6/2014
• The ACTUS Story; A new bioaccelerator model for the age of biotechnology 
  Bioindustry Organization of Southern Arizona - 3/2014
• Targeting neoplasms and atherosclerosis using novel targeted-nanoworm constructs 
  Partnerships in Drug Delivery; Boston, MA - 10/2013
• Convoy Therapeutics; altering the topical treatment paradigm 
  Partnerships in Drug Delivery; Boston, MA - 10/2013
• The new FDA regulatory environment and its effect on medical device approvals 
  BioConference Live; Irvine, CA - 8/2010
• The development and characterization of transgenic and gene targeted animal models 
  California Lutheran University; Thousand Oaks, CA - 4/2003
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Other

• Compositions and method for manipulating pim-1 activity in circulatory system cells 
  Muraski JA, Sussman MA, USPTO Application Number: 19/0060417A1
  2/2019
• Skin penetrating peptides (spps) and methods of use therefor 
  Muraski JA, Mitragotri S, Chen M, Application Number: WO 2016033314A1
  6/2016
• Skin permeating and cell entering (space) peptides and methods of use therefor 
  Muraski JA, Mitragotri S, Kumar S, Application Number: PCT/US2013/025543
  2/2013
• Composition and methods for operating the pim-1 activity in circulatory system cells 
  Muraski JA, Sussman MA, JPPTO Application Number: JP2011-503207A
  1/2011
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