KonstantinosArnaoutakisMD

Oncology • Little Rock, AR

Associate Professor, Internal Medicine, University of Arkansas COM

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Office
UAMS Medical Center
449 Jack Stephens Drive Winthrop P. Rockefeller Cancer Institute, Seventh Floor
Little Rock, AR 72205
Phone+1 501-686-8530
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Education & Training

St Elizabeth's Medical CenterFellowship, Hematology and Medical Oncology, 2006 - 2009
Albany Medical CenterResidency, Internal Medicine, 2003 - 2006
University of Patras School of MedicineClass of 1998

Certifications & Licensure

MA State Medical License 2006 - 2025
AR State Medical License 2009 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Hematology
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2014

Clinical Trials

Chemotherapy Plus Cetuximab in Combination With VTX-2337 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Start of enrollment: 2013 Oct 14
Completed
Phase 2
Vaccination of Advanced-Stage Lung Cancer Patients Start of enrollment: 2015 Oct 01
Withdrawn
Phase 1, Phase 2
A Pilot Study to Assess the Immunogenicity of Candidate PSA Peptides for a Prostate Cancer Vaccine Start of enrollment: 2015 Aug 01
Completed
Not Applicable
A Feasibility Study to Further the Development of Lung Cancer-based Precision Medicine Start of enrollment: 2016 Jan 01
Active, not recruiting
Not Applicable
Lung-MAP: Taselisib as Therapy in Treating Patients With Stage IV Squamous Cell Lung Cancer and Positive Biomarker Matches Start of enrollment: 2014 Nov 01
Completed
Phase 2
Lung-MAP: Palbociclib as Second-Line Therapy in Treating Cell Cycle Gene Alteration Positive Patients With Recurrent Stage IV Squamous Cell Lung Cancer Start of enrollment: 2014 Sep 01
Completed
Phase 2, Phase 3
Lung-MAP: Nivolumab With or Without Ipilimumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers Start of enrollment: 2015 Dec 29
Active, not recruiting
Phase 3
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Publications & Presentations

PubMed

Stem Cell Origin of Cancer: Clinical Implications beyond Immunotherapy for Drug versus Therapy Development in Cancer Care.
Anup K Trikannad, Nazish Malik, Shi-Ming Tu, Sruthi Vellanki, Munawwar Hussain, Sunny R Singh, Anusha Jillella, Sri Obulareddy, Sindhu Malapati, Sajjad A Bhatti, Konst...> ;Cancers. 2024 Mar 14
4 citations
Stem Cell Theory of Cancer: Implications for Translational Research from Bedside to Bench.
Shi-Ming Tu, Sunny R Singh, Konstantinos Arnaoutakis, Sindhu Malapati, Sajjad A Bhatti, Aron Y Joon, Omar T Atiq, Louis L Pisters> ;Cancers. 2022 Jul 9
Hematology/Oncology Fellowship Programs' Participation in the Quality Oncology Practice Initiative.
Issam Makhoul, Michael Anders, Robert Siegel, Anne Chiang, Merry-Jennifer Markham, Ronald C Chen, Sarah Mougalian, Konstantinos Arnaoutakis, Meredith Giuliani, Annie I...> ;JCO Oncology Practice. 2022 Jul 1
An advanced molecular medicine case report of a rare human tumor using genomics, pathomics, and radiomics.
Li Ma, Erich A Peterson, Ik Jae Shin, Jason Muesse, Katy Marino, Mathew A Steliga, Omar Atiq, Konstantinos Arnaoutakis, Christopher Wardell, Jacob Wooldridge, Fred Pri...> ;Frontiers in Genetics. 2022 Jan 1
2 citations
A novel prostate cancer immunotherapy using prostate-specific antigen peptides and Candida skin test reagent as an adjuvant.
Al-Ola Abdallah, Hannah N. Coleman, Mohamed Kamel, Rodney Davis, Teri Landrum, Horace J. Spencer, Samuel G. Mackintosh, Fade Mahmoud, Natasa Milojkovic, Chester Wicker...> ;SAGE Open Medicine. 2018 Sep 17
67 citations
PARP1 Is Up-Regulated in Non-small Cell Lung Cancer Tissues in the Presence of the Cyanobacterial Toxin Microcystin
Patrick L. Apopa, Lisa Alley, Rosalind B. Penney, Konstantinos Arnaoutakis, Mathew Steliga, Susan Jeffus, Emine Bircan, Banu Gopalan, Jing Jin, Preecha Patumcharoenpol...> ;Frontiers in Microbiology. 2018 Aug 6
13 citations
Cancer patient perspectives regarding preparedness for end-of-life care: A qualitative study.
Allen C. Sherman, Stephanie Simonton-Atchley, Cindy W. Mikeal, Kendra M. Anderson, Konstantinos Arnaoutakis, Laura F. Hutchins, Issam Makhoul, Fade Mahmoud, Natasa Mil...> ;Journal of Psychosocial Oncology. 2018 Jun 4
31 citations
Liquid biopsy and its role in an advanced clinical trial for lung cancer.
Donald J. Johann, Mathew Steliga, Ik Jae Shin, Donghoon Yoon, Konstantinos Arnaoutakis, Laura F. Hutchins, Meeiyueh Liu, Jason Liem, Karl Walker, Andy Pereira, Mary Ya...> ;Experimental Biology and Medicine. 2018 Feb 6
Integrating Collaborative Learning and Competition in a Hematology/Oncology Training Program.
Issam Makhoul, Pooja Motwani, Liudmila Schafer, Konstantinos Arnaoutakis, Fade Mahmoud, Mazin Safar, Dorothy A. Graves, Paulette Mehta, Rang Govindarajan, Laura F. Hut...> ;Journal of Cancer Education. 2018 Feb 1
10 citations
Clonal Evolution and the Role of Serial Liquid Biopsies in a Case of Small-Cell Lung Cancer-Transformed EGFR Mutant Non-Small-Cell Lung Cancer.
Meghan J. Mooradian, Zofia Piotrowska, Benjamin J. Drapkin, Dora Dias-Santagata, Nicolas Marcoux, Konstantinos Arnaoutakis, Rebecca J. Nagy, Richard B. Lanman, Anthony...> ;JCO Precision Oncology. 2017 Nov 7
17 citations
Targeting nano drug delivery to cancer cells using tunable, multi-layer, silver-decorated gold nanorods.
Zeid A. Nima, Ahmed Alwbari, Vijayalakshmi Dantuluri, Rabab N. Hamzah, Natasha Sra, Pooja Motwani, Konstantinos Arnaoutakis, Rebecca A. Levy, Amani F. Bohliqa, Dmitry ...> ;Journal of Applied Toxicology. 2017 Jul 21
25 citations
Hyalinizing Clear Cell Carcinoma of the Lung: Case Report and Review of the Literature.
Susanne K. Jeffus, Jerad M. Gardner, Matthew A. Steliga, Akeesha A. Shah, Edward B. Stelow, Konstantinos Arnaoutakis> ;American Journal of Clinical Pathology. 2017 Jul 1
3 citations
Addressing Opioid-Associated Constipation Using Quality Oncology Practice Initiative Scores and Plan-Do-Study-Act Cycles.
Varinder Kaur, Sajjad Haider, Appalanaidu Sasapu, Paulette Mehta, Konstantinos Arnaoutakis, Issam Makhoul> ;Journal of Oncology Practice. 2017 Jan 1
2 citations
Improving Communication on Intent of Chemotherapy Using QOPI Scores and PDSA Cycles
Meghana Bansal, Al-Ola Abdallah, Angela Pennisi, Konstantinos Arnaoutakis, Issam Makhoul, Paulette Mehta> ;Journal of Cancer Education. 2016 Dec 1
An Unusual Case of Acute Promyelocytic Leukemia Presenting With Hypoplastic Bone Marrow and Pancytopenia.
Rahul Ravilla, Daisy Alapat, Konstantinos Arnaoutakis, Amy K. Joiner> ;The American Journal of the Medical Sciences. 2016 Mar 1
3 citations
Simulating Four Essential Conversations with Hematology/Oncology Trainees: a Qualitative Evaluation.
Konstantinos Arnaoutakis, Michael Anders, Katherine Berry> ;Journal of Cancer Education. 2016 Mar 1
1 citations
Metastatic Renal Cell Carcinoma Presenting as Painful Chewing Successfully Treated with Combined Nivolumab and Sunitinib.
Fade Mahmoud, Al-Ola Abdallah, Konstantinos Arnaoutakis, Issam Makhoul> ;The Permanente Journal. 2016 Jun 27
Myxoid mesenchymal neoplasm presenting as massive arm and chest wall oedema with pleural effusion.
Vidya B Pai, Rahul Ravilla, Matthew R. Lindberg, Matthew A. Steliga, Konstantinos Arnaoutakis> ;Ecancermedicalscience. 2015 Nov 4
2 citations
Molecular Markers in the Diagnosis and Treatment of Cancer.
Murat Gokden, Aurelio Ariza, Konstantinos Arnaoutakis> ;Biomed Research International. 2015 Sep 14
63 citations
Crizotinib in ROS1-rearranged non-small-cell lung cancer.
Konstantinos Arnaoutakis> ;The New England Journal of Medicine. 2015 Feb 12
3 citations
Rituximab and intermediate-purity plasma-derived factor VIII concentrate (Koate®) as adjuncts to therapeutic plasma exchange for thrombotic thrombocytopenic purpura in...
Soumya Pandey, Mayumi Nakagawa, Eric R Rosenbaum, Konstantinos Arnaoutakis, Laura F. Hutchins, Issam Makhoul, Natasha Milojkovic, Michele Cottler-Fox> ;Journal of Clinical Apheresis. 2015 Feb 1
1 citations
The role of salvage hemiscrotectomy in testicular cancer after scrotal contamination: a case report and literature review.
Reshma Khetpal, Matthew D. Katz, Michelle Cox, Konstantinos Arnaoutakis> ;Clinical Genitourinary Cancer. 2014 Jun 1
1 citations
Accuracy of fine needle aspiration and core lung biopsies to predict histology in patients with non-small cell lung cancer.
William Whitney Robertson, Matthew A. Steliga, Eric R. Siegel, Konstantinos Arnaoutakis> ;Medical Oncology. 2014 Apr 29
6 citations
Primary bone marrow Hodgkin lymphoma in an HIV-negative patient
Bhagirathbhai Dholaria, Daisy Alapat, Konstantinos Arnaoutakis> ;International Journal of Hematology. 2014 Feb 15
2 citations
Paralyzed by a rare cause: an unusual case of metastatic diffuse large B cell lymphoma of the intramedullary spinal cord.
Arpit Rao, Richard Griffiths, Konstantinos Arnaoutakis> ;Annals of Hematology. 2014 Feb 1
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Press Mentions

New UAMS Baptist Health Cancer Center Opens in North Little RockAugust 30th, 2021
OncLive® Presents State of the Science Summit™ on Non-Small Cell Lung CancerJune 12th, 2019
Upfront Osimertinib Shows No Survival Advantage but Slows Brain Progression in EGFR-Mutant NSCLC TrialMarch 12th, 2024