MichaelJamesQuonMDPhD

PubMed

• 4 citations
  When MINMOD Artifactually Interprets Strong Insulin Secretion as Weak Insulin Action.
  Joon Ha, Ranganath Muniyappa, Arthur Sherman, Michael J. Quon> ;Frontiers in Physiology. 2021 Apr 22
• 33 citations
  Endothelial dysfunction due to selective insulin resistance in vascular endothelium: insights from mechanistic modeling
  Ranganath Muniyappa, Hui Chen, Monica Montagnani, Arthur Sherman, Michael J. Quon> ;American Journal of Physiology. Endocrinology and Metabolism. 2020 Aug 10
• 17 citations
  Race affects the association of obesity measures with insulin sensitivity
  Jeannie Tay, Amy M. Goss, W. Timothy Garvey, Mark E. Lockhart, Nikki C. Bush, Michael J. Quon, Gordon Fisher, Barbara A. Gower> ;The American Journal of Clinical Nutrition. 2020 Mar 1
• 12 citations
  Simvastatin Treatment Protects Myocardium in Noncoronary Artery Cardiac Surgery by Inhibiting Apoptosis Through miR-15a-5p Targeting
  Li Zhou, Xiang Liu, Zhen-Qing Wang, Yan Li, Mao-Mao Shi, Zhe Xu, Zhi-Jun Ou, Hua-Ming Li, Tian-Pu Cheng, Yu-Peng Jian, Wen Zhang, Chen Liu, Xi Zhang, Michael J. Quon, ...> ;Journal of Cardiovascular Pharmacology. 2018 Oct 1
• 8 citations
  Monocyte DPP4 Expression in Human Atherosclerosis Is Associated With Obesity and Dyslipidemia.
  Xiaoquan Rao, Jeffrey A. Deiuliis, Georgeta Mihai, Juliet Varghese, Chang Xia, Matthew B. Frieman, Carole Sztalryd, Xiao Jian Sun, Michael J. Quon, Simeon I. Taylor, S...> ;Diabetes Care. 2018 Jan 1
• 1 citations
  Transgenic mice with ectopic expression of constitutively active TLR4 in adipose tissues do not show impaired insulin sensitivity.
  Kikumi D. Ono-Moore, Ling Zhao, Shurong Huang, Jeong-a Kim, Jennifer M. Rutkowsky, Ryan G. Snodgrass, Dina A. Schneider, Michael J. Quon, James L. Graham, Peter J. Hav...> ;Immunity, Inflammation and Disease. 2017 Aug 4
• 25 citations
  Deletion of interleukin 1 receptor-associated kinase 1 ( Irak1 ) improves glucose tolerance primarily by increasing insulin sensitivity in skeletal muscle.
  Xiao Jian Sun, Soohyun Park Kim, Dongming Zhang, Helen Sun, Qi Cao, Xin Lu, Zhekang Ying, Liwu Li, Robert R. Henry, Theodore P. Ciaraldi, Simeon I. Taylor, Michael J. ...> ;The Journal of Biological Chemistry. 2017 Jul 21
• 17 citations
  Combining Potent Statin Therapy with Other Drugs to Optimize Simultaneous Cardiovascular and Metabolic Benefits while Minimizing Adverse Events
  Kwang Kon Koh, Ichiro Sakuma, Kazunori Shimada, Toshio Hayashi, Michael J. Quon> ;Korean Circulation Journal. 2017 Jul 1
• 10 citations
  Acute vascular and metabolic actions of the green tea polyphenol epigallocatechin 3-gallate in rat skeletal muscle
  Huei Leng Helena Ng, Dino Premilovac, Stephen Rattigan, Stephen M. Richards, Ranganath Muniyappa, Michael J. Quon, Michelle A. Keske> ;The Journal of Nutritional Biochemistry. 2017 Feb 1
• 13 citations
  Infliximab therapy restores adiponectin expression in perivascular adipose tissue and improves endothelial nitric oxide-mediated vasodilation in mice with type 1 diabetes
  Carmela Nacci, Valentina Leo, Leonarda De Benedictis, Maria Assunta Potenza, Luca Sgarra, Maria Antonietta De Salvia, Michael J. Quon, Monica Montagnani> ;Vascular Pharmacology. 2016 Dec 1
• 34 citations
  Direct Evidence that Myocardial Insulin Resistance following Myocardial Ischemia Contributes to Post-Ischemic Heart Failure
  Feng Fu, Kun Zhao, Jia Li, Jie Xu, Yuan Zhang, Chengfeng Liu, Weidong Yang, Chao Gao, Jun Li, Haifeng Zhang, Yan Li, Qin Cui, Haichang Wang, Ling Tao, Jing Wang, Micha...> ;Scientific Reports. 2016 Nov 1
• 12 citations
  Estrogen deprivation in primate pregnancy leads to insulin resistance in offspring.
  Adina Maniu, Graham W. Aberdeen, Terrie J. Lynch, Jerry L. Nadler, Soon Ok Kim, Michael J. Quon, Gerald J. Pepe, Eugene D. Albrecht> ;The Journal of Endocrinology. 2016 Aug 1
• 16 citations
  Dominant negative FADD dissipates the proapoptotic signalosome of the unfolded protein response in diabetic embryopathy.
  Fang Wang, Hongbo Weng, Michael J. Quon, Jingwen Yu, Jian-Ying Wang, Anne-Odile Hueber, Peixin Yang> ;American Journal of Physiology. Endocrinology and Metabolism. 2015 Nov 15
• 35 citations
  ASK1 mediates the teratogenicity of diabetes in the developing heart by inducing ER stress and inhibiting critical factors essential for cardiac development
  Fang Wang, Yanqing Wu, Michael J. Quon, Xuezheng Li, Peixin Yang> ;American Journal of Physiology. Endocrinology and Metabolism. 2015 Sep 1
• 40 citations
  Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels
  Wensheng Lu, Yu-Ching Cheng, Keping Chen, Hong Wang, Glenn S. Gerhard, Xin Chu, Rongze Yang, Ankita Parihar, Jeffrey R. O'Connell, Toni I. Pollin, Eduardo Anglés-Cano,...> ;Human Molecular Genetics. 2015 Apr 15
• 56 citations
  Cellular stress, excessive apoptosis and the effect of metformin in a mouse model of type 2 diabetic embryopathy
  Yanqing Wu, Fang Wang, Mao Fu, Cheng Wang, Michael J. Quon, Peixin Yang> ;Diabetes. 2015 Feb 25
• 1 citations
  Man shall not live by bread alone.
  Fredrik H. Nystrom, Michael J. Quon> ;Nutrition. 2015 Jan 1
• 57 citations
  Vascular and metabolic actions of the green tea polyphenol epigallocatechin gallate.
  Michelle A. Keske, Huei Leng Helena Ng, Dino Premilovac, Stephen Rattigan, Jeong-a Kim, Kashif M. Munir, Peixin Yang, Michael J. Quon> ;Current Medicinal Chemistry. 2014 Dec 31
• Response to Comment on Sarkar et al. Exenatide Treatment for 6 Months Improves Insulin Sensitivity in Adults With Type 1 Diabetes. Diabetes Care 2014;37:666–670
  Gayatri Sarkar, May Alattar, Rebecca J. Brown, Michael J. Quon, David M. Harlan, Kristina I. Rother> ;Diabetes Care. 2014 Oct 1
• 99 citations
  Modulation of adiponectin as a potential therapeutic strategy.
  Soo Lim, Michael J. Quon, Kwang Kon Koh> ;Atherosclerosis. 2014 Apr 1
• 57 citations
  Exenatide Treatment for 6 Months Improves Insulin Sensitivity in Adults With Type 1 Diabetes
  Gayatri Sarkar, May Alattar, Rebecca J. Brown, Michael J. Quon, David M. Harlan, Kristina I. Rother> ;Diabetes Care. 2014 Mar 1
• 19 citations
  Differential Metabolic Actions of Specific Statins: Clinical and Therapeutic Considerations
  Soo Lim, Ichiro Sakuma, Michael J. Quon, Kwang Kon Koh> ;Antioxidants & Redox Signaling. 2014 Feb 21
• 415 citations
  New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate.
  Hae Suk Kim, Michael J. Quon, Jeong-a Kim> ;Redox Biology. 2014 Jan 1
• 31 citations
  Improvement of vascular insulin sensitivity by downregulation of GRK2 mediates exercise-induced alleviation of hypertension in spontaneously hypertensive rats
  Wenjuan Xing, Youyou Li, Haifeng Zhang, Chunjuan Mi, Zuoxu Hou, Michael J. Quon, Feng Gao> ;American Journal of Physiology. Heart and Circulatory Physiology. 2013 Oct 15
• 25 citations
  Combination Pravastatin and Valsartan Treatment Has Additive Beneficial Effects to Simultaneously Improve Both Metabolic and Cardiovascular Phenotypes Beyond That of M...
  Kwang Kon Koh, Soo Lim, Hanul Choi, Yonghee Lee, Seung Hwan Han, Kyounghoon Lee, Pyung Chun Oh, Ichiro Sakuma, Eak Kyun Shin, Michael J. Quon> ;Diabetes. 2013 Oct 1
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Journal Articles

• Differential metabolic actions of specific statins: clinical and therapeutic considerations  
  Lim, S., Sakuma, I., Quon, M.J., Koh, K.K., Antioxid.Redox Signal., 1/1/2014
• Exenatide treatment for 6 months improves insulin sensitivity in adults with type 1 diabetes mellitus  
  Sarkar, G., Alattar, M., Brown, R.J., Quon, M.J., Harlan, D.M., Rother, K.I., Diabetes Care, 1/1/2014
• New insights into the mechanisms of polyphenols beyond antioxidant properties: lessons from the green tea polyphenol epigallocatechin 3-gallate  
  Kim, J., Kim, H., Quon, M.J., Redox Biology, 1/1/2014
• Modulation of adiponectin as a potential therapeutic strategy  
  Lim, S., Quon, M.J., Koh, K.K., Atherosclerosis, 1/1/2014
• Differential metabolic effects of rosuvastatin and pravastatin in hypercholesterolemic patients  
  Koh, K.K., Quon, M.J., Sakuma, I., Han, S.H., Choi, H., Lee, K., Shin, E., Int. J. Cardiol., 1/1/2013
• Toll like receptor 2 mediates high fat diet-induced impairment of vasodilator actions of insulin  
  Jang, H.J., Kim, H.S., Hwang, D.H., Quon, M.J., Kim, J.A., Am. J. Physiol. Endocrinol. Metab., 1/1/2013
• Distinct mechanisms for globular adiponectin to integrate vascular and metabolic actions of insulin to help maintain coordinated cardiovascular and glucose homeostasis  
  Munir, K.M., Quon, M.J., Circ. Res., 1/1/2013
• Potentially important considerations in choosing specific statin treatments to reduce overall morbidity and mortality  
  Lim, S., Sakuma, I., Quon, M.J., Koh, K.K., Int. J. Cardiol., 1/1/2013
• Mechanisms for food polyphenols to ameliorate insulin resistance and endothelial dysfunction: therapeutic implications for diabetes and its vascular complications  
  Munir, K.M., Quon, M.J., Am. J. Physiol. Endocrinol. Metab., 1/1/2013
• Combination pravastatin and valsartan treatment have additive beneficial effects to simultaneously improve both metabolic and cardiovascular phenotypes beyond that of ...  
  Koh, K.K., Lim, S., Choi, H., Lee, Y., Han, S., Lee, K., Oh, P., Sachiro, I., Shin, E., Quon, M.J., Diabetes, 1/1/2013
• Improvement of vascular insulin sensitivity by downregulation of GRK2 mediates exercise-induced alleviation of hypertension in spontaneously hypertensive rats  
  Xing, W., Li, Y., Zhang, H., Mi, C., Hou, Z., Quon, M.J., Gao, F., Am. J. Physiol. Heart Circ. Physiol., 1/1/2013
• Caveats to Aggressive Lowering of Lipids by Specific Statins  
  Koh, K.K., Lim, S., Sakuma, I., Quon, M.J., Int. J. Cardiol., 1/1/2012
• Epigallocatechin gallate induces expression of heme oxygenase-1 in endothelial cells via p38 MAPK and Nrf-2 that suppresses pro-inflammatory actions of TNF-alpha  
  Pullikotil, P., Chen, H., Muniyappa, R., Greenberg, C.C., Yang, S., Reiter, C.E.N., Lee, J.W., Chung, J.H., and Quon, M.J., J. Nutr. Biochem, 1/1/2012
• Deterioration of glucose homeostasis in type 2 diabetic patients one year after beginning of statins therapy  
  Bellia, A., Rizza, S., Lombardo, M.F., Donadel, G., Fabiano, R., Andreadi, K., Quon, M.J., Sbraccia, P., Federici, M., Tesaura, M., Cardillo, C., Lauro, D., Atherosclerosis, 1/1/2012
• Role of lipotoxicity in endothelial dysfunction  
  Kim, J.A., Montagnani, M., Chandresekran, S., Quon, M.J., Heart Failure Clin., 1/1/2012
• Extracellular conversion of adiponectin hexamers into trimers  
  Kim, J.A., Nuñez, M., Briggs, D.B., Laskowski, B.L., Chhun, J.J., Eleid, J.K., Quon, M.J., Tsao, T.S., Biosci. Rep., 1/1/2012
• Additive beneficial effects of atorvastatin combined with amlodipine in patients with mild-to-moderate hypertension  
  Koh, K.K., Quon, M.J., Han, S.H., Lee Y., Park, J.B., Kim, S.J., Koh, Y., Shin, E.K., Int. J. Cardiol., 1/1/2011
• Effects of simvastatin therapy on circulating adipocytokines in patients with hypercholesterolemia  
  Koh, K.K., Quon, M.J., Sakuma, I., Lee, Y., Lim, S., Han, S.H., Shin, E.K., Int. J. Cardiol., 1/1/2011
• Protein Kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate activity of VCAM-1  
  Lee, J.W., Chen, H., Pullikotil, P., Quon, M.J., J. Biol. Chem., 1/1/2011
• Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells whil improving endothelial function and reucing inflammatory markers in patient...  
  Rizza, S., Muniyappa R., Iantorno, M., Kim, J.A., Chen, H., Pullikotil, P., Senese, N., Tesauro, M., Lauro, D., Cardillo, C., Quon, M.J., J. Clin. Endocrinol. Metab., 1/1/2011
• B4GALNT3 expression predicts a favorable prognosis and suppresses cell migration and invasion via Beta1 Integrin signaling in neuroblastoma  
  Hsu, W.M., Che, M.L., Liao, Y.F., Chang, H.H., Chen, C.H., Huang, Y.M., Jeng, Y.M., Huang, J., Quon, M.J., Lee, H., Huang, H.C., Huang, M.C., Am. J. Pathol., 1/1/2011
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  Addabbo, F., Nacci C., De Benedictus, L., Leo, V., Tarquinio, M., Quon, M.J., Montagnani, M., Am. J. Physiol. Endocrinol. Metab., 1/1/2011
• Epigallocatechin gallate, a green tea polyphenol, reduces endothelin-1 expression in vascular endothelial cells through FOXO1-dependent transcriptional regulation  
  Reiter, C.E.N., Kim, J., Quon, M.J., Endocrinology, 1/1/2010
• Simple modeling allows prediction of steady-state glucose disposal rate from early data in Hyperinsulinemic glucose clamps  
  Singal, P., Muniyappa, R. Chisolm, R., Hall, G., Quon, M.J., Mather, K.J., Am. J. Physiol. Endocrinol. Metab., 1/1/2010
• Atorvastatin causes insulin resistance and increases ambient glycemia in hypercholesterolemic patients  
  Koh, K.K., Quon, M.J., Han, S.H., Lee, Y., Kim, S.J., Shin, E.K., J. Am. Coll. Cardiol., 1/1/2010
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Books/Book Chapters

• Insulin Resistance: New Research 
  Chapter: Insulin resistance and endothelial dysfunction: an unhappy union. 
  Page 117 - 136Iantorno, M., Muniyappa, R., Quon, M.J.Editors: E.B. Yao.Nova Science Publishers, Inc., Hauppauge, NY2009
• Contemporary Endocrinology: The Metabolic Syndrome: Epidemiology, Clinical Treatment, and Underlying Mechanisms 
  Chapter: Insulin action and endothelial function. 
  Page 107 - 137Mather K., Baron, A.D., Quon, M.J.Editors: B.C. Hansen, G.A. Bray.Humana Press Inc.2007
• Signal Transduction and Human Disease 
  Chapter: Molecular and cellular aspects of insulin resistance: implications for diabetes. 
  Page 171 - 200LeRoith, D., Quon, M.J., Zick, Y.Editors: T. Finkel, J.S. Gutkind.Wiley Interscience, Inc., New Jersey2003
• Hormone Signaling 
  Chapter: Insulin and insulin-like growth factor-1 receptors and signaling pathways: similarities and differences. 
  Page 81 - 99LeRoith, D., Quon, M.J., Zick, Y.Editors: V. Goffin, P.A. Kelly.Kluwer Academic Publishers, Boston, MA2002
• Frontiers in Animal Diabetes Research, Insulin Signaling: From Cultured Cells to Animal Models 
  Chapter: Insulin action in vascular endothelium. 
  Quon, M.J.Editors: G. Grunberger, Y. Zick.2001
• Gene Engineering in Endocrinology 
  Chapter: Insulin action: molecular mechanisms and determinants of specificity. 
  Page 17 - 38Quon, M.J., Taylor, S.I.Editors: M.A. Shupnik.Humana Press Inc., NJ2000
• Contemporary Endocrinology: Insulin Resistance: The Metabolic Syndrome X 
  Chapter: Insulin action and endothelial function. 
  Page 247 - 263Baron, A.D., Quon, M.J.Editors: G.M. Reaven, A. Laws.Humana Press Inc., NJ1999
• DNA Transfer to Cultured Cells: Culture of Specialised Cells Vol. 4 
  Chapter: Transfection of rat adipose cells by electroporation. 
  Page 93 - 109Quon, M.J.Editors: K. Ravid, R.I. Freshney.Wiley-Liss, Inc., NY1998
• Endocrine Reviews Monographs 2. The Endocrine Pancreas, Insulin Action, and Diabetes 
  Chapter: Mutations in the insulin receptor gene: Update 1994. 
  Page 58 - 65Taylor, S.I., Wertheimer, E., Accili, D., Cama, A., Hone, J., Roach, P., Quon, M.J., Suzuki, Y., Levy-Toledano, R., Taouis, M., Sierra, M.L., Barbetti. F., Gorden, P.Editors: L.E. Underwood.Endocrine Society Press1994
• Molecular Biology of Diabetes, Part II 
  Chapter: Mutations in the insulin receptor gene in patients with genetic syndromes of extreme insulin resistance. 
  Page 1 - 23Taylor, S.I., Wertheimer, E., Hone, J., Levy-Toledano, R., Quon, M.J., Barbetti, F., Suzuki, Y., Roach, P., Koller, E., Haft, C.R., Sierra, M.L., Cama, A., Accili, D.Editors: B. Draznin, D. LeRoith.Humana Press Inc., NJ1994
• New Perspectives in Endocrinology, Serono Symposia Publications Vol. 99 
  Chapter: Five mutations in the human insulin receptor gene: effects on insulin-stimulated c-jun induction and thymidine incorporation. 
  Page 359 - 368Quon, M.J., Cama, A., Taylor, S.I.Editors: A. DeBellis, K.B. Marschke.Raven Press, New York1993
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Abstracts/Posters

• Vascular and metabolic effects of candesartan: insights from therapeutic interventions.
  Koh, K.K., Quon, M.J., Han, S.H., Chung, W.J. Kim, J., Shin, E.K., J. Hypertens., 1/1/2006
• Reciprocal relationships between insulin resistance and endothelial dysfunction: insights from therapeutic interventions.
  Quon, M.J., Zhong Nan Da Xue Xue Bao Yi Xue Ban, 1/1/2006
• Insulin signaling and the link to endothelial dysfunction.
  Quon, M.J., Endocr. Pract., 1/1/2003
• Mechanisms of hormone resistance: lessons from insulin-resistant patients.
  Taylor, S.I., Accili, D., Haft, C.R., Hone, J., Imai, Y., Levy-Toledano, R., Quon, M.J., Suzuki, Y., Wertheimer, E., Acta Paediatr, 1/1/1994
• Mutations in the insulin receptor gene in insulin resistant patients.
  Taylor, S.I., Accili, D., Cama, A., Koller, E., Levy-Toledano, R., Quon, M.J., Sierra, M.L., Wertheimer, E., Proceedings of the Ninth International Congress of Endocrinology, 1/1/1992
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Lectures

• Reciprocal Relationships Between Endothelial Dysfunction and Insulin Resistance: Therapeutic Implications. 
  University of Louisville, KY - 8/16/2013
• Donepezil, an Acetylcholinesterase Inhibitor Used to Treat Alzheimer Dementia, Ameliorates Insulin Resistance in Spontaneously Hypertensive Rats (SHR). 
  First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China - 4/12/2013
• Endothelial Dysfunction and Insulin Resistance: Combination Therapy Approaches. 
  Gachon Medical School, Incheon, Korea - 9/18/2012
• Beneficial Cardiovascular and Metabolic Actions of Polyphenols from Functional Foods Including Green Tea and Citrus. 
  4/12/2012
• Novel Biological Actions of the Green Tea Polyphenol EGCG Related to Vascular and Metabolic Health. 
  University of Virginia, Charlottesville, VA - 4/3/2012
• Endothelial Dysfuntion in Type 2 Diabetes. 
  University of Chieti, Chieti, Italy - 11/19/2011
• Novel Molecular Mechanisms of Action for the Green Tea Polyphenol EGCG. 
  University of Rome, Tor Vergata, Rome, Italy - 11/14/2011
• Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction: Therapeutic Implications. 
  Eastern Virginia Medical School, Norfolk, VA - 11/9/2011
• Everything You Wanted to Know about Simple Surrogate Indexes for Insulin Sensitivity/Resistance in Humans. 
  Johns Hopkins University, Baltimore, MD - 10/26/2011
• Everything You Wanted to Know about Minimal Model Analysis and Simple Surrogate Indexes for Insulin Sensitivity/Resistance in Humans. 
  NIDDK, NIH, Bethesda, MD - 9/26/2011
• Everything You Wanted to Know about Glucose Clamps in Humans. 
  NIDDK, NIH, Bethesda, MD - 9/19/2011
• Guidelines for Preparing Fundable Competitive Research Grant Proposals. 
  The University of Hong Kong Li Ka Shing Faculty of Medicine, Hong Kong - 8/7/2011
• Methods for Measuring Insulin Sensitivity/Resistance in Humans, Animals, and Cells: advantages, limitations, and appropriate usage. 
  Baltimore, MD - 7/11/2011
• Merck Medical Forum on Cellular Pathophysiology Associated with Type 2 Diabetes. 
  San Diego, CA - 6/27/2011
• Insulin resistance and endothelial dysfunction related to diabetes. 
  Seoul, Korea - 8/14/2010
• Reciprocal relationships between insulin resistance and endothelial dysfunction: implications for therapeutic nutritional supplements and functional foods. 
  Auburn, AL - 3/26/2010
• Beneficial vascular and metabolic actions of the green tea polyphenol EGCG. 
  Tucson, AZ - 10/8/2009
• An integrated view of insulin resistance and endothelial dysfunction. 
  New Orleans, LA - 6/5/2009
• Reciprocal relationships between endothelial dysfunction and insulin resistance: focus on molecular, cellular, physiological, and translational aspects. 
  Seoul, Korea - 5/16/2009
• Green tea polyphenols for the treatment of diabetes and its cardiovascular complications. 
  Changsha, China - 4/21/2009
• Novel vascular actions of DHEA and EGCG that mimic insulin action. 
  Medical College of Georgia, Augusta, GA - 4/30/2008
• Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction: from cells to humans. 
  USDA, Beltsville Human Nutrition Research Center, Beltsville, MD - 3/11/2008
• Effects of EGCG and DHEA to mimic vascular actions of insulin. 
  Virginia Tech, Blacksburg, VA - 12/14/2007
• Epigallocatechin gallate, a green tea polyphenol, ameliorates metabolic syndrome abnormalities. 
  Washington, DC - 11/14/2007
• Inflammatory markers and the metabolic syndrome. 
  New York, NY - 10/23/2007
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