NealHermanowiczMD

Neurology • Rancho Mirage, CA

Movement Disorder

Neurology, Christus- St. Vincent Medical Center, Sanat Fe, NM

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Office
39000 Bob Hope Dr.
Probst Bldg., Ste. 311
Rancho Mirage, CA 92270
Phone+1 760-837-8785
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Education & Training

University of Michigan Health SystemFellowship, Neuromuscular Medicine (Neurology), 1989 - 1991
University of Wisconsin Hospitals and ClinicsChief Residency, Neurology, 1988 - 1989
U Wisconsin Hospital and Clinics1986 - 1989
University of Wisconsin Hospitals and ClinicsInternship, Internal Medicine, 1985 - 1986
Lewis Katz School of Medicine at Temple UniversityClass of 1985
University of Illinois at Urbana-ChampaignBS, Chemistry, 1972 - 1976

Certifications & Licensure

NM State Medical License 1991 - 2025
CA State Medical License 1997 - 2024
IL State Medical License 1996 - 1999
MI State Medical License 1989 - 1993
WI State Medical License 1986 - 1989
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

Orange County Physician of Excellence Orange County Medical Association with Orange Coast Magazine, 2006, 2007, 2010, 2006-2018
Best Doctor, Neurology Best Doctors, Inc., 2013-2017
Top Doctors:LA Area Castle Connolly, 2013
Top Doctors:San Diego Area Castle Connolly, 2013
Palm Springs Life Magazine Castle Connolly, 2006-2013
Top Doctors:Southern California Castle Connolly, 2012
Faculty Teaching University of California, Irvine, 2008
Faculty Appreciation University of California, Irvine, 2005
Pioneer Hall of Fame University High School Normal, Illinois, 2004
Dystonia Doctor of Excellence San Diego County Support Group of the Dystonia Medical Research Foundation, 2003
Lamport Award for Medical Student Research Temple University School of Medicine, 1983
Clinical Excellence Evanston Hospital-Northshore University Healthsystem, 1977
Bachelor of Science with Highest Distinction in the Chemistry University of Illinois, 1976
Phi Lambda Upsilon The National Honorary Chemical Society University of Illinois, 1975
Phi Kappa Phi, Honor Society University of Illinois, 1975
Super Doctor SuperDoctors.com
Top MD Consumers Checkbook
President Orange County Neurological Society, 1998-2000
Physician of Excellence US News/Castle Connolly/Palm Springs Life Magazine, 2007-2012
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Clinical Trials

Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain Start of enrollment: 2005 Apr 01
Unknown status
Not Applicable
Creatine Safety, Tolerability, & Efficacy in Huntington's Disease (CREST-E) Start of enrollment: 2009 Sep 01
Terminated
Phase 3
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort Start of enrollment: 2012 Jul 01
Recruiting
Safety and Efficacy of Fenofibrate as a Treatment for Huntington's Disease Start of enrollment: 2017 Apr 27
Completed
Phase 2
VY-AADC02 for Parkinson's Disease With Motor Fluctuations (RESTORE-1) Start of enrollment: 2018 Oct 17
Active, not recruiting
Phase 1
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Publications & Presentations

PubMed

8 citations
Impact of Isolation During the COVID-19 Pandemic on the Patient Burden of Parkinson's Disease: A PMD Alliance Survey.
Neal Hermanowicz, Maria Cristina Ospina, Yasar Torres-Yaghi, Sherrie Gould, Kelly Papesh, Jason A Rivera, Susan Miller, Sarah Jones, Kelli Musick, Damian May> ;Neuropsychiatric Disease and Treatment. 2022 Jan 1
Adult Abdominal Migraine Improved by OnabotulinumtoxinA Injections.
Neal Hermanowicz> ;Case Reports in Neurology. 2021 Jan 1
17 citations
Fosmetpantotenate Randomized Controlled Trial in Pantothenate Kinase–Associated Neurodegeneration
Thomas Klopstock, Aleksandar Videnovic, Almut Turid Bischoff, Cecilia Bonnet, Laura Cif, Cynthia L. Comella, Marta Correa-Vela, Maria L. Escolar, Jamie L. Fraser, Vict...> ;Movement Disorders. 2021 Jun 1
31 citations
PKG Movement Recording System Use Shows Promise in Routine Clinical Care of Patients With Parkinson's Disease.
Rajeshree Joshi, Jeffrey M. Bronstein, Adrienne M. Keener, Jaclyn Alcazar, Diane D. Yang, Maya Joshi, Neal Hermanowicz> ;Frontiers in Neurology. 2019 Oct 1
9 citations
Two-year clinical outcomes associated with robotic-assisted subthalamic lead implantation in patients with Parkinson's disease.
Michelle Paff, Alice S Wang, Nicolas Phielipp, Sumeet Vadera, Anna Morenkova, Neal Hermanowicz, Frank P.K. Hsu> ;Journal of Robotic Surgery. 2020 Aug 1
38 citations
Impact of non-motor symptoms in Parkinson's disease: a PMDAlliance survey.
Neal Hermanowicz, Sarah A Jones, Robert A. Hauser> ;Neuropsychiatric Disease and Treatment. 2019 Aug 5
4 citations
Changing the treatment paradigm for Parkinson's disease psychosis with pimavanserin.
Kelly E. Lyons, Rajesh Pahwa, Neal Hermanowicz, Thomas L. Davis, Fernando Pagan, Stuart Isaacson> ;Expert Review of Clinical Pharmacology. 2019 Jun 13
7 citations
Patient and physician perceptions of disease management in Parkinson’s disease: results from a US-based multicenter survey
Neal Hermanowicz, Michelle Castillo-Shell, Angela McMean, Jesse Fishman, Joseph D'Souza> ;Neuropsychiatric Disease and Treatment. 2019 May 30
Assessing and addressing footwear needs in Parkinson's disease-design thinking in neurology.
Jamasb J. Sayadi, Lohrasb R Sayadi, Arman Fijany, Mustafa Chopan, Neal Hermanowicz> ;Neurorehabilitation. 2019 Jan 1
Neurological commentary addressing the article titled "Guidance for switching from off-label antipsychotics to pimavanserin for Parkinson's disease psychosis: an exper...
Neal Hermanowicz> ;CNS Spectrums. 2018 Dec 1
3 citations
Delusional misidentification in Parkinson's disease: report of two cases and a review.
Neal Hermanowicz> ;Postgraduate Medicine. 2018 Feb 17
2 citations
The Emerging Role of Pimavanserin in the Management of Parkinson’s Disease Psychosis
Neal Hermanowicz, Gustavo Alva, Fernando Pagan, Alberto J. Espay, Amita Patel, Katya Cruz Madrid, Daniel Kremens, Jim Kenney, Sheila Arquette, Gary Tereso, Maria Lopes...> ;Journal of Managed Care & Specialty Pharmacy. 2017 Jun 21
22 citations
Clinical utility of DaTscan™ imaging in the evaluation of patients with parkinsonism: a US perspective.
Stuart Isaacson, Stanley Fisher, Fiona Gupta, Neal Hermanowicz, Daniel Kremens, Mark F. Lew, Kenneth Marek, Rajesh Pahwa, David S. Russell, John Seibyl> ;Expert Review of Neurotherapeutics. 2017 Mar 1
85 citations
A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease
Andrew McGarry, Michael P. McDermott, Karl Kieburtz, Elisabeth A. deBlieck, Flint Beal, Karen Marder, Christopher A. Ross, Ira Shoulson, Peter R. Gilbert, William Mall...> ;Neurology. 2017 Jan 10
29 citations
Frameless Stereotactic Robot-Assisted Subthalamic Nucleus Deep Brain Stimulation: Case Report.
Sumeet Vadera, Alvin Y. Chan, Thomas Lo, Amandip S Gill, Anna Morenkova, Nicolas Phielipp, Neal Hermanowicz, Frank P.K. Hsu> ;World Neurosurgery. 2017 Jan 1
8 citations
The safety, tolerability and efficacy of pimavanserin tartrate in the treatment of psychosis in Parkinson’s disease
Stefan Hermanowicz, Neal Hermanowicz> ;Expert Review of Neurotherapeutics. 2016 Jun 1
4 citations
The Effect of Gabapentin Enacarbil on Pain Associated with Moderate-to-Severe Primary Restless Legs Syndrome in Adults: Pooled Analyses from Three Randomized Controlle...
Neal Hermanowicz, Aaron Ellenbogen, Gordon Irving, Mark J. Buchfuhrer, Mark J. Jaros, Gwendoline Shang, Richard Kim> ;CNS Drugs. 2016 Apr 19
4 citations
Effect of prior exposure to dopamine agonists on treatment with gabapentin enacarbil in adults with moderate-to-severe primary restless legs syndrome: pooled analyses ...
William G. Ondo, Neal Hermanowicz, Diego García Borreguero, Mark J. Jaros, Richard Kim, Gwendoline Shang> ;Journal of Clinical Movement Disorders. 2015 Mar 30
21 citations
Parkinson's disease psychosis: symptoms, management, and economic burden.
Neal Hermanowicz, Kari Edwards> ;The American Journal of Managed Care. 2015 Aug 17
2 citations
Colorectal surgery in Parkinson's disease--outcomes and predictors of mortality.
Grace S. Hwang, Monica T. Young, Mark H. Hanna, Gopal Menon, Michael J. Phelan, Joseph C. Carmichael, Steven Mills, Michael J. Stamos, Neal Hermanowicz, Alessio Pigazzi> ;International Journal of Colorectal Disease. 2015 Jun 4
232 citations
A Randomized Clinical Trial of High-Dosage Coenzyme Q10 in Early Parkinson Disease: No Evidence of Benefit
M. Flint Beal, David Oakes, Ira Shoulson, Claire Henchcliffe, Wendy R. Galpern, Richard H. Haas, Jorge L. Juncos, John G. Nutt, Tiffini Voss, Bernard Ravina, Clifford ...> ;JAMA Neurology. 2014 May 1
35 citations
A randomized, double-blind, placebo-controlled study of latrepirdine in patients with mild to moderate Huntington disease.
K. Kieburtz, Georg Bernhard Landwehrmeyer, Merit Cudkowicz, E. R. Dorsey, Andrew Feigin, Vicki Hunt, Elise Kayson, Michael P. McDermott, S Noonberg, W Seitz, Paola Sol...> ;JAMA Neurology. 2013 Jan 1
Creation of an open-access, mutation-defined fibroblast resource for neurological disease research.
Wray S Self M Lewis PA Taanman JW Ryan NS Mahoney CJ Liang Y Devine MJ Sheerin UM Houlden H Morris HR Healy D Marti-Masso JF Preza E Barker S Sutherland M Corriveau RA...> ;PLoS One . 2012
Immediate versus delayed switch from levodopa/carbidopa to levodopa/carbidopa/entacapone: effects on motor function and quality of life in patients with Parkinson's di...
Lew MF Somogyi M McCague K Welsh M > ;Int J Neurosci . 2011 Nov
Predictors of time to requiring dopaminergic treatment in 2 Parkinson's disease cohorts.
Marras C McDermott MP Marek K Rochon P Naglie G Tanner CM Rudolph A Shoulson I Lang AE > ;Mov Disord . 2011 Mar
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Journal Articles

Involvement of spectrin in the maintenance of phase state asymmetry in the erythrocyte membrane.
Williamson P., Bateman J., Kozarsky K., Mattocks K., Choe H.R, Hermanowicz N, Schlegel R.A, Cell, 1982; 30: 725-733
Abnormal membrane methylation and merocyanine 540 fluorescence in sickle cell erythrocyte membranes.
Manna C., Hermanowicz N, Ro J.Y., Neilan B., Glushko V., Kim S, Biochemical Medicine, 1984; 31: 362-370
Clinical evaluation of bidirectional torticollis.
Truong DD, Hermanowicz NS, Mov Disord. 1990;5(2):181
Rabbit syndrome treated with botulin.
Truong DD, Hermanowicz N, Mistura K, South Med J. 1990 Jul;83(7):854-5
Botulinum toxin in treatment of tardive dyskinetic syndrome.
Truong DD, Hermanowicz N, Rontal M, J Clin Psychopharmacol. 1990 Dec;10(6):438-9
Posttraumatic torticollis.
Truong DD, Dubinsky R, Hermanowicz N, Olson WL, Silverman B, Koller WC, Arch Neurol. 1991 Feb;48(2):221-3
Treatment of oromandibular dystonia with botulinum toxin.
Hermanowicz N, Truong D, Laryngoscope, 1991; 101: 1216-1218
Development of botulinum toxin therapy.
Hermanowicz N, Truong DD, West J Med. 1995 Nov;163(5):472-3
Cognitive-motor learning in Parkinson's disease.
Haaland K., Harrington D., O'Brien S. and Hermanowicz N, Neuropsychology, 1997; 11(2): 180-186
Temporal processing in the basal ganglia.
Harrington D., Haaland K., Hermanowicz N, Neuropsychology, 1998; 12(1): 3-12
Management of Parkinson's disease. Strategies, pitfalls, and future directions.
Hermanowicz N, Postgrad Med. 2001 Dec;110(6):15-8, 21-3, 28
Significant linkage of Parkinson disease to chromosome 2q36-37.
Pankratz N, Nichols WC, Uniacke SK, Halter C, Rudolph A, Shults C, Conneally PM, Foroud T and the Parkinson Study Group, Am J Human Genet 2003;72:1053-1057
Genome-Wide Linkage Analysis and Evidence of Gene-by-Gene Interactions in a Sample of 362 Multiplex Parkinson Disease Families.
Pankratz N, Nichols WC, Uniacke SK, Halter C, Murrell J, Rudolph A, Shults C, Conneally PM, Foroud T, and the Parkinson Study Group, Human Molecular Genetics 2003;12:2599-2608
Evaluation of the Role of Nurr1 in a Large Sample of Familial Parkinson’s Disease.
Nichols WC, Uniacke SK, Pankratz N, Reed T, Simon DK, Halter C, Rudolph A, Shults C, Conneally PM, Foroud T, and the Parkinson Study Group, Movement Disorders 2004;19(6):649-655
Genes influencing Parkinson disease onset: replication of PARK3 and identification of novel loci.
Pankratz N, Uniacke SK, Halter CA, Rudolph A, Shults CW, Conneally PM, Foroud T, Nicholas WC and the Parkinson Study Group, Neurol 2004;62:1616-1618
A randomized placebo-controlled trial of rasagiline in levodopa-treated Parkinson’s disease patients with motor fluctuations (The PRESTO Study).
Parkinson Study Group, Arch Neurol 2005;62:241-248
Rasagiline improves quality of life in patients with early Parkinson’s disease.
Biglan K, Schwid S, Eberly S, Blindauer K, Fahn F, Goren T, Kieburtz K, Oakes D, Plumb S, Siderowf A, Stern M, Shoulson I and the Parkinson Study Group, Mov Disord 2006;DOI 10.1002/mds.20764
Safety of rasagiline in elderly patients with Parkinson disease.
Goetz CG, Schwid SR, Eberly SW, Oakes D, Shoulson I and the Parkinson Study Group TEMPO and PRESTO Investigators, Neurology 2006;66:1427-1429
Mutations in DJ-1 are rare in familial Parkinson disease.
Pankratz N, Pauciulo MW, Elsaesser VE, et al, Neurosci Lett. 2006 Nov 20;408(3):209-13
R1514Q substitution in Lrrk2 is not a pathogenic Parkinson's disease mutation.
Nichols WC, Marek DK, Pauciulo MW, et al, Mov Disord. 2006 Dec 5;22(2):254-256
Mutations in LRRK2 other than G2019S are rare in a north American-based sample of familial Parkinson's disease.
Pankratz N, Pauciulo MW, Elsaesser VE, et al, Mov Disord. 2006 Dec;21(12):2257-60
Serum urate as a predictor of clinical and radiographic progression in Parkinson disease.
Schwarzschild MA, Schwid SR, Marek K, Watts A, Lang AE, Oakes D, Shoulson I, Ascherio A; Parkinson Study Group PRECEPT Investigators, Hyson C, Gorbold E, Rudolph A, Ki..., Arch Neurol. 2008 Jun;65(6):716-23
Long-term treatment with botulinum toxin type A in cervical dystonia has low immunogenicity by mouse protection assay.
Brin MF, Comella CL, Jankovic J, Lai F, Naumann M; CD-017 BoNTA Study Group, Mov Disord. 2008 Jul 30;23(10):1353-60
Parkinson's Rasagiline: Efficacy and Safety in the Treatment of Off Parkinson Study Group. Transtelephonic home blood pressure to assess the monoamine oxidase-B inhibi...
White WB, Salzman P, Schwid SR, Hypertension. 2008 Sep;52(3):587-93
Clinical correlates of depressive symptoms in familial Parkinson's disease.
Pankratz N, Marder KS, Halter CA, Rudolph A, Shults CW, Nichols WC, Foroud T; Parkinson's Study Group-PROGENI Investigators, Mov Disord. 2008 Nov 15;23(15):2216-23
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Books/Book Chapters

Textbook of Clinical Neurology.
Chapter: Cranial Nerves IX (Glossopharyngeal) and X (Vagus)
Page 211 - 222Hermanowicz NEditors: Goetz CG.Elsevier, Philadelphia
Encyclopedia of Movement Disorders.
Chapter: Hemiballismus
Page 14 - 17Hermanowicz NEditors: Kompoliti K and verhagen L.Elsevier, Philadelphia

Lectures

Parkinson’s disease: new directions.
Salt Lake City Parkinson’s disease organization
Cervical dystonia: Diagnosis and treatment.
Asia-Oceanian Conference for Physical and Rehabilitative Medicine. Nanjing, China
Dementia and Parkinson’s disease.
Orange County Alzheimer’s Disease Association Annual Symposium. Irvine, CA
Huntington’s disease. Frontiers of the Mind.
University of California, Irvine
Unusual Movement Disorders.
The Brain and Spine Forum, Huntington Hospital. Pasadena, CA
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Press Mentions

What Every Family Needs to Know About Parkinson’s DiseaseOctober 24th, 2019
Caltech Study Finds Link Between Parkinson's Disease and Gut BacteriaDecember 1st, 2016
What to Ask Your Doctor About Parkinson’s DiseaseFebruary 17th, 2018