OscarJohnAbilezMDPhD

Research • Stanford, CA

Principle Investigator-Stanford Pediatric Cardiac Surgery

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Office
Stanford University
Clark Center E250, 318 West Campus Dr
Stanford, CA 94305
Phone+1 650-223-5876
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Education & Training

Stanford UniversityPhD, Bioengineering, 2007 - 2012
Stanford Health Care-Sponsored Stanford UniversityResidency, Surgery, 2003 - 2004
Stanford Health Care-Sponsored Stanford UniversityInternship, Surgery, 2002 - 2003
Weill Cornell MedicineClass of 2002

Publications & Presentations

PubMed

12 citations
Transcriptome analysis of non human primate-induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer culture vs. 3D engineered heart tissue.
Huaxiao Yang, Ning-Yi Shao, Alexandra Holmström, Xin Zhao, Tony Chour, Haodong Chen, Ilanit Itzhaki, Haodi Wu, Mohamed Ameen, Nathan J. Cunningham, Chengyi Tu, Ming-Ta...> ;Cardiovascular Research. 2021 Jul 27
91 citations
Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling.
Oscar J. Abilez, Evangeline Tzatzalos, Huaxiao Yang, Ming-Tao Zhao, Gwanghyun Jung, Alexander M. Zöllner, Malte Tiburcy, Johannes Riegler, Elena Matsa, Praveen K. Shuk...> ;Stem Cells. 2018 Feb 1
120 citations
iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy.
Kazuki Kodo, Sang-Ging Ong, Fereshteh Jahanbani, Vittavat Termglinchan, Keiichi Hirono, Kolsoum InanlooRahatloo, Antje D. Ebert, Praveen K. Shukla, Oscar J. Abilez, Ja...> ;Nature Cell Biology. 2016 Oct 1
5 citations
Stem cell reprogramming: A 3D boost
Oscar J. Abilez, Joseph C. Wu> ;Nature Materials. 2016 Mar 1
1 citations
Stem cell isolation: Differential stickiness.
Oscar J. Abilez, Joseph C. Wu> ;Nature Materials. 2013 Jun 1
71 citations
Multiscale Computational Models for Optogenetic Control of Cardiac Function
Oscar J. Abilez, Jonathan Wong, Rohit Prakash, Karl Deisseroth, Christopher K. Zarins, Ellen Kuhl> ;Biophysical Journal. 2011 Sep 21
12 citations
Human pluripotent stem cell tools for cardiac optogenetics.
Yan Zhuge, Bhagat Patlolla, Charu Ramakrishnan, Ramin E. Beygui, Christopher K. Zarins, Karl Deisseroth, Ellen Kuhl, Oscar J. Abilez> ;Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2014 Nov 6
29 citations
In vivo imaging and evaluation of different biomatrices for improvement of stem cell survival.
Feng Cao, Amir H Sadrzadeh Rafie, Oscar J. Abilez, Haichang Wang, Jennifer T. Blundo, Beth L. Pruitt, Christopher K. Zarins, Joseph C. Wu> ;Journal of Tissue Engineering and Regenerative Medicine. 2007 Nov 1
29 citations
Endogenous retrovirus-derived lncRNA BANCR promotes cardiomyocyte migration in humans and non-human primates
Kitchener D. Wilson, Mohamed Ameen, Hongchao Guo, Oscar J. Abilez, Lei Tian, Maxwell R. Mumbach, Sebastian Diecke, Xulei Qin, Yonggang Liu, Huaxiao Yang, Ning Ma, Sadh...> ;Developmental Cell. 2020 Sep 28
76 citations
An in Vivo miRNA Delivery System for Restoring Infarcted Myocardium
Huaxiao Yang, Xulei Qin, Huiyuan Wang, Xin Zhao, Yonggang Liu, Hung-Ta Wo, Chun Liu, Masataka Nishiga, Haodong Chen, Jing Ge, Nazish Sayed, Oscar J. Abilez, Dan Ding, ...> ;ACS Nano. 2019 May 31
44 citations
Treatment of volumetric muscle loss in mice using nanofibrillar scaffolds enhances vascular organization and integration
Karina H. Nakayama, Marco Quarta, Patrick Paine, Cynthia Alcazar, Ioannis Karakikes, Victor Garcia, Oscar J. Abilez, Nicholas S. Calvo, Chelsey S. Simmons, Thomas A. R...> ;Communications Biology. 2019 May 7
51 citations
Big bottlenecks in cardiovascular tissue engineering.
Ngan F. Huang, Vahid Serpooshan, Viola B. Morris, Nazish Sayed, Gaspard Pardon, Oscar J. Abilez, Karina H. Nakayama, Beth L. Pruitt, Sean M. Wu, Young Sup Yoon, Jianyi...> ;Communications Biology. 2018 Nov 21
2 citations
Optophysiology of cardiomyocytes: characterizing cellular motion with quantitative phase imaging.
Christine Cordeiro, Oscar J. Abilez, Georges Goetz, Tushar Gupta, Yan Zhuge, Olav Solgaard, Daniel Palanker> ;Biomedical Optics Express. 2017 Sep 22
49 citations
Anisotropic microfibrous scaffolds enhance the organization and function of cardiomyocytes derived from induced pluripotent stem cells
Maureen Wanjare, Luqia Hou, Karina H. Nakayama, Joseph J. Kim, Nicholas P. Mezak, Oscar J. Abilez, Evangeline Tzatzalos, Joseph C. Wu, Ngan F. Huang> ;Biomaterials Science. 2017 Jul 26
15 citations
Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons.
Wenpo Chuang, Arun Sharma, Praveen K. Shukla, Guang Li, Moritz Mall, Kuppusamy Rajarajan, Oscar J. Abilez, Joseph C. Wu, Marius Wernig, Sean M. Wu> ;Scientific Reports. 2017 Mar 22
102 citations
Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies.
Evangeline Tzatzalos, Oscar J. Abilez, Praveen K. Shukla, Joseph C. Wu> ;Advanced Drug Delivery Reviews. 2016 Jan 15
24 citations
CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells
Rhys J.P. Skelton, Bevin Brady, Suhail Khoja, Debashis Sahoo, James L. Engel, Deevina Arasaratnam, Kholoud K. Saleh, Oscar J. Abilez, Peng Zhao, Edouard G. Stanley, An...> ;Stem Cell Reports. 2016 Jan 12
148 citations
Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model
Johannes Riegler, Malte Tiburcy, Antje D. Ebert, Evangeline Tzatzalos, Uwe Raaz, Oscar J. Abilez, Qi Shen, Nigel G. Kooreman, Evgenios Neofytou, Vincent C. Chen, Mouer...> ;Circulation Research. 2015 Sep 25
40 citations
Multi-cellular interactions sustain long-term contractility of human pluripotent stem cell-derived cardiomyocytes.
Paul W. Burridge, Scott A. Metzler, Karina H. Nakayama, Oscar J. Abilez, Chelsey S. Simmons, Marc A. Bruce, Yuka Matsuura, Paul J Kim, Joseph C. Wu, Manish J. Butte, N...> ;American Journal of Translational Research. 2014 Nov 22
87 citations
Effect of human donor cell source on differentiation and function of cardiac induced pluripotent stem cells
Veronica Sanchez-Freire, Andrew S. Lee, Shijun Hu, Oscar J. Abilez, Ping Liang, Feng Lan, Bruno C. Huber, Sang-Ging Ong, Wan Xing Hong, Mei Huang, Joseph C. Wu> ;Journal of the American College of Cardiology. 2014 Aug 5
990 citations
Chemically defined generation of human cardiomyocytes
Paul W. Burridge, Elena Matsa, Praveen K. Shukla, Ziliang C Lin, Jared M. Churko, Antje D. Ebert, Feng Lan, Sebastian Diecke, Bruno C. Huber, Nicholas M. Mordwinkin, J...> ;Nature Methods. 2014 Aug 1
19 citations
Robust pluripotent stem cell expansion and cardiomyocyte differentiation via geometric patterning
Frank B. Myers, Jason S. Silver, Yan Zhuge, Ramin E. Beygui, Christopher K. Zarins, Luke P. Lee, Oscar J. Abilez> ;Integrative Biology. 2013 Nov 18
4 citations
Optogenetic LED array for perturbing cardiac electrophysiology
Oscar J. Abilez> ;Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2013 Jul 3
51 citations
Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue
Reza Ardehali, Shah R. Ali, Matthew A. Inlay, Oscar J. Abilez, Michael Q. Chen, Timothy A. Blauwkamp, Masayuki Yazawa, Yongquan Gong, Roeland Nusse, Micha Drukker, Irv...> ;Proceedings of the National Academy of Sciences of the United States of America. 2013 Feb 26
462 citations
Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells
Feng Lan, Andrew S. Lee, Ping Liang, Veronica Sanchez-Freire, Patricia K. Nguyen, Li Wang, Leng Han, Michelle Yen, Yongming Wang, Ning Sun, Oscar J. Abilez, Shijun Hu,...> ;Cell Stem Cell. 2013 Jan 3
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