PamelaLZeitlinMD

PubMed

• In Response.
  Amy J Lee, Julie L Huffmyer, Pamela L Zeitlin, Debnath Chatterjee, Thiele, E.> ;Anesthesia and Analgesia. 2022 Jul 1
• The Changing Face of Cystic Fibrosis: An Update for Anesthesiologists.
  Amy J Lee, Julie L Huffmyer, Pamela L Zeitlin, Debnath Chatterjee, Eryn L Thiele> ;Anesthesia and Analgesia. 2022 Jun 1
• 2 citations
  Net benefit of ivacaftor during prolonged tezacaftor/elexacaftor exposure in vitro.
  Ciaran A Shaughnessy, Pamela L Zeitlin, Preston E Bratcher> ;Journal of Cystic Fibrosis. 2022 Jul 1
• 5 citations
  Receptor-mediated activation of CFTR via prostaglandin signaling pathways in the airway.
  Ciaran A Shaughnessy, Sangya Yadav, Preston E Bratcher, Pamela L Zeitlin> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2022 Mar 1
• 2 citations
  Measurements of spontaneous CFTR-mediated ion transport without acute channel activation in airway epithelial cultures after modulator exposure.
  Heidi J. Nick, Pamela L. Zeitlin, Sangya Yadav, Preston E. Bratcher> ;Scientific Reports. 2021 Nov 19
• Author Correction: Elexacaftor is a CFTR potentiator and acts synergistically with ivacaftor during acute and chronic treatment.
  Ciaran A. Shaughnessy, Pamela L. Zeitlin, Preston E. Bratcher> ;Scientific Reports. 2021 Oct 25
• 31 citations
  Elexacaftor is a CFTR potentiator and acts synergistically with ivacaftor during acute and chronic treatment.
  Ciaran A. Shaughnessy, Pamela L. Zeitlin, Preston E. Bratcher> ;Scientific Reports. 2021 Oct 6
• Expanding CFTR Modulator Testing to Carriers of CFTR Variants.
  Preston E. Bratcher, Pamela L. Zeitlin> ;Annals of the American Thoracic Society. 2021 Nov 1
• 1 citations
  Characterizing mucociliary clearance in young children with cystic fibrosis.
  Beth L. Laube, Kathryn A. Carson, Christopher M. Evans, Melis A. Aksit, Joseph M. Collaco, Vanessa L. Richardson, Gail Sharpless, Pamela L. Zeitlin, Garry R. Cutting, ...> ;Pediatric Research. 2021 Mar 22
• 3 citations
  Downregulation of epithelial sodium channel (ENaC) activity in human airway epithelia after low temperature incubation.
  Sangya Yadav, Ciaran A. Shaughnessy, Pamela L. Zeitlin, Preston E. Bratcher> ;BMJ Open Respiratory Research. 2021 Feb 1
• 6 citations
  Effect of apical chloride concentration on the measurement of responses to CFTR modulation in airway epithelia cultured from nasal brushings.
  Preston E. Bratcher, Sangya Yadav, Ciaran A. Shaughnessy, Ian M. Thornell, Pamela L. Zeitlin> ;Physiological Reports. 2020 Oct 1
• 3 citations
  Cystic fibrosis transmembrane conductance regulator function, not TAS2R38 gene haplotypes, predict sinus surgery in children and young adults with cystic fibrosis
  Nicholas M. Dalesio, Melis Atalar Aksit, Kwangmi Ahn, Karen S. Raraigh, Joseph M. Collaco, Sharon A. McGrath-Morrow, Pamela L. Zeitlin, Steven S. An, Garry R. Cutting> ;International Forum of Allergy & Rhinology. 2020 Apr 13
• 6 citations
  Changes in mucociliary clearance over time in children with cystic fibrosis.
  Beth L. Laube, Kathryn A. Carson, Christopher M. Evans, Vanessa L. Richardson, Gail Sharpless, Pamela L. Zeitlin, Peter J. Mogayzel> ;Pediatric Pulmonology. 2020 May 19
• 11 citations
  Impact of sleep opportunity on asthma outcomes in adolescents.
  Lisa J. Meltzer, Dean W. Beebe, Stephanie Jump, Kassie D. Flewelling, D. Sundström, Michael White, Pamela L. Zeitlin, Matthew Strand> ;Sleep Medicine. 2020 Jan 1
• 44 citations
  Effect of ivacaftor on mucociliary clearance and clinical outcomes in cystic fibrosis patients with G551D-CFTR
  Scott H. Donaldson, Beth L. Laube, Timothy E. Corcoran, Pradeep Bhambhvani, Kirby L. Zeman, Agathe Ceppe, Pamela L. Zeitlin, Peter J. Mogayzel, Michael P. Boyle, Lando...> ;JCI Insight. 2018 Dec 20
• 24 citations
  Benralizumab does not impair antibody response to seasonal influenza vaccination in adolescent and young adult patients with moderate to severe asthma: results from th...
  Pamela L. Zeitlin, Mila Leong, Jeremy Cole, Raburn M. Mallory, Vivian H. Shih, Richard F. Olsson, Mitchell Goldman> ;Journal of Asthma and Allergy. 2018 Aug 16
• 36 citations
  Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR
  Scott H. Donaldson, George M. Solomon, Pamela L. Zeitlin, Patrick A. Flume, Alicia Casey, Karen McCoy, Edith T. Zemanick, Arun Mandagere, Janice M. Troha, Steven A. Sh...> ;Journal of Cystic Fibrosis. 2017 May 1
• 18 citations
  Digitoxin for Airway Inflammation in Cystic Fibrosis: Preliminary Assessment of Safety, Pharmacokinetics, and Dose Finding.
  Pamela L. Zeitlin, Marie Diener-West, Karen Callahan, Seakwoo Lee, C Conover Talbot, Bette Pollard, Michael P. Boyle, Noah Lechtzin> ;Annals of the American Thoracic Society. 2017 Feb 1
• 146 citations
  Airway microbiota across age and disease spectrum in cystic fibrosis
  Edith T. Zemanick, Brandie D. Wagner, Charles E. Robertson, Richard C. Ahrens, James F. Chmiel, John P. Clancy, Ronald L. Gibson, William T. Harris, Geoffrey Kurland, ...> ;The European Respiratory Journal. 2017 Nov 1
• 32 citations
  Clinical Phenotypes and Genotypic Spectrum of Cystic Fibrosis in Chinese Children.
  Yuelin Shen, Jinrong Liu, Lili Zhong, Peter J. Mogayzel, Pamela L. Zeitlin, Patrick R. Sosnay, Shunying Zhao> ;The Journal of Pediatrics. 2016 Apr 1
• 4 citations
  Direct interactions between ENaC gamma subunit and ClCN2 in cystic fibrosis epithelial cells
  Katherine R. Henry, Seakwoo Lee, Douglas Walker, Pamela L. Zeitlin> ;Physiological Reports. 2015 Jan 1
• 12 citations
  Interference with ubiquitination in CFTR modifies stability of core glycosylated and cell surface pools.
  Seakwoo Lee, Mark J. Henderson, Eric Schiffhauer, Jordan Despanie, Katherine R. Henry, Po Wei Kang, Douglas Walker, Michelle L. McClure, Landon Wilson, Eric J. Sorsche...> ;Molecular and Cellular Biology. 2014 Jul 15
• 250 citations
  Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial
  Eitan Kerem, Michael W. Konstan, Kris De Boeck, Frank J. Accurso, Isabelle Sermet-Gaudelus, Michael Wilschanski, J. Stuart Elborn, Paola Melotti, Inez Bronsveld, Isabe...> ;The Lancet. Respiratory Medicine. 2014 Jul 1
• 21 citations
  Dual activation of CFTR and CLCN2 by lubiprostone in murine nasal epithelia.
  Eric Schiffhauer, Neeraj Vij, Olga Kovbasnjuk, Po Wei Kang, Doug Walker, Seakwoo Lee, Pamela L. Zeitlin> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2013 Mar 1
• 6 citations
  Antibody Microarrays: Analysis of Cystic Fibrosis
  Catherine Jozwik, Harvey B. Pollard, Meera Srivastava, Ofer Eidelman, Qingyuan Fan, Thomas N. Darling, Pamela L. Zeitlin> ;Methods in Molecular Biology. 2012 Jan 1
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Journal Articles

• Clinical Phenotypes and Genotypic Spectrum of Cystic Fibrosis in Chinese Children  
  Shen, Y, Liu, J, Zhong, L, Mogayzel, PJ, Zeitlin, PL, Sosnay, PR, and Zhao, S, J Pediatr., 1/1/2016
• Use of ibuprofen to assess inflammatory biomarkers in induced sputum: Implications for clinical trials in cystic fibrosis  
  Chmiel JF, Konstan MW, Accurso FJ, Lymp J, Mayer-Hamblett N, VanDevanter DR, Rose LM, Ramsey BW; Assessment of Induced Sputum in Cystic Fibrosis Study Group, J Cyst Fibros, 1/1/2015
• Interference with ubiquitination in CFTR modifies stability of core glycosylated and cell surface pools  
  Lee S, Henderson MJ, Schiffhauer E, Despanie J, Henry K, Kang PW, Walker D, McClure ML, Wilson L, Sorscher EJ, Zeitlin PL, Mol Cell Biol., 1/8/2014
• Dual activation of CFTR and CLCN2 by lubiprostone in murine nasal epithelial  
  Schiffhauer, E, Vij N, Kovbasnjuk, O, Kang PW, Walker D, Lee S, Zeitlin, PL, Am J Physiol Lung Cell Mol Physiol, 1/1/2013
• Standard care versus protocol based therapy for new onset Pseudomonas aeruginosa in cystic fibrosis  
  Mayer-Hamblett N, Rosenfeld M, Treggiari MM, Konstan MW, Retsch-Bogart G, Morgan W, Wagener J, Gibson RL, Khan U, Emerson J, Thompson V, Elkin EP, Ramsey BW; EPIC; ESC..., Pediatr Pulmonol, 1/1/2013
• Initial Pseudomonas aeruginosa treatment failure is associated with exacerbations in cystic fibrosis  
  Mayer-Hamblett N, Kronmal RA, Gibson RL, Rosenfeld M, Retsch-Bogart G, Treggiari MM, Burns JL, Khan U, Ramsey BW; EPIC Investigators (Zeitlin PL), Pediatr Pulmonol, 1/1/2012
• Highlights from the latest articles in cystic fibrosis clinical and translational sciences  
  Zeitlin PL, Therapy, 1/1/2011
• Etiology of bronchodpulmonary dysplasia: before birth  
  Zeitlin, PL and L. Nogee, Ped Allergy Immunol Pulmonol, 1/1/2011
• Comparative efficacy and safety of 4 randomized regimens to treat early Pseudomonas aeruginosa infection in children with cystic fibrosis  
  Treggiari MM, Retsch-Bogart G, Mayer-Hamblett N, Khan U, Kulich M, Kronmal R, Williams J, Hiatt P, Gibson RL, Spencer T, Orenstein D, Chatfield BA, Froh DK, Burns JL, ..., Arch Pediatr Adolesc Med., 1/1/2011
• Denufosol tetrasodium in patients with cystic fibrosis and normal to mildly impaired lung function  
  Accurso FJ, Moss RB, Wilmott RW, Anbar RD, Schaberg AE, Durham TA, Ramsey BW; TIGER-1 Investigator Study Group (Zeitlin PL), Arch Pediatr Adolesc Med, 1/1/2011
• Ubiquitin C-terminal Hydrolase-L1 protects cystic fibrosis transmembrane conductance regulator from early stages of proteasomal degradation  
  Henderson, MJ, Vij N, and Zeitlin, PL, J. Biol. Chem., 1/1/2010
• Applications of proteomic technologies for understanding the premature proteolysis of CFTR  
  Henderson, MJ, Singh, OV, and Zeitlin, PL, Expert Rev. Proteomics, 1/1/2010
• Elevated serum IL-8 levels in ataxia telangiectasia  
  McGrath-Morrow SA, Collaco JM, Crawford TO, Carson KA, Lefton-Greif MA, Zeitlin P, Lederman HM, J Pediatr., 1/1/2010
• Genetic Modifiers of Liver Disease in Cystic Fibrosis  
  Bartlett JL, Bartlett JR, Friedman KJ, Ling SC, Pace RG, Bell SC, Bourke B, Castaldo G, Castellani C, Cipolli M, Colombo C, Colombo JL, Debray D, Fernandez A, Lacaille..., JAMA, 1/9/2009
• Pseudomonas aeruginosa: can studies in engineered cells tell us why is it such a problem in people with cystic fibrosis? Focus on "Cystic fibrosis transmembrane conduc...  
  Zeitlin PL, Am J Physiol Cell Physiol, 1/1/2009
• Spiperone, Identified through Compound Screening, Activates Calcium Dependent Chloride Secretion in the Airway  
  Liang L, Macdonald KD, Schwiebert EM, Zeitlin PL, Guggino WB, Am J Physiol Cell Physiol, 1/1/2009
• Proteome of synatptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury  
  Singh, OV, Yaster M, Xu, JT, Guan Y, Guan X, Dhamarajan AM, Raja SN, Zeitlin PL and Tao, YX, Proteomics, 1/1/2009
• CFTR is a negative regulator of NFKbeta mediated innate immune response  
  Vij, N, Mazur, S, and Zeitlin, PL, PLoS ONE, 1/1/2009
• Atypical cystic fibrosis and CFTR related diseases (Review)  
  Paranjape, SM, and Zeitlin, PL, Clin Rev Allergy Immunol, 1/1/2008
• Cystic fibrosis presenting as recurrent pancreatitis in a young child with a normal sweat test and pancreas divisum: a case report  
  Conklin, L, Zeitlin, PL, and Cuffari, C, J. Med. Case Reports, 1/1/2008
• Lubiprostone activates non-CFTR dependent respiratory epithelial chloride secretion in cystic fibrosis mice  
  MacDonald, KD, McKenzie, KR, Henderson, MJ, Hawkins, CE, Vij, N, and Zeitlin, PL, J Physiol Lung Cell Mol Physiol, 1/1/2008
• Patients with mutations in Gsalpha have reduced activation of a downstream target in epithelial tissues due to haploinsufficiency  
  Hsu, SC, Groman JD, Merlo CA, Naughton K, Zeitlin PL, Germain-Lee EL, Boyle MP, and GR Cutting, J. Clin. Endocrin. Metab., 1/24/2007
• CHOP Transcription Factor Mediates IL-8 Signaling in Cystic Fibrosis Bronchial Epithelial Cells  
  Vij, N, Amoako MO, Mazur S, and PL Zeitlin, Am J Respir Cell Mol Biol., 1/20/2007
• Cystic fibrosis transmembrane regulator protein mutations: 'class' opportunity for novel drug innovation  
  MacDonald KM, McKenzie K and PL Zeitlin, Paediatr Drugs, 1/1/2007
• Emerging drug treatments for cystic fibrosis  
  Zeitlin PL, Expert Opin. Emerging Drugs, 1/1/2007
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Books/Book Chapters

• Kendig and Chernicks’ Disorders of the Respiratory Tract in Children 
  Chapter: Genetics and Pathophysiology of cystic fibrosis 
  Page 753 - 763Cutting, GR, Zeitlin, PLEditors: Wilmott.Elsevier SaundersEdition 8th,2012
• Clinics in Chest Medicine - Cystic Fibrosis 
  Chapter: Therapies Directed at the Basic Defect in Cystic Fibrosis 
  Page 515 - 525Zeitlin PLEditors: Fiel.W.B. Saunders, Phila., PA1998
• Gene Therapy for Diseases of the Lung 
  Chapter: Adeno-associaed viral vectors 
  Page 53 - 81Zeitlin PLEditors: Brigham KL.Marcel Dekker Inc., New York, NY1997
• Les medicaments de la mucoviscidose chez l'enfant 
  Chapter: Pharmacological Approaches to Correct Defective CFTR Function 
  Page 155 - 164Zeitlin PL, and Guggino WBEditors: Pons G, Lenoir G, and Navarro J.Springer-Verlag, Paris Franc1997
• Critical Heart Disease in Infants 
  Chapter: Cor Pulmonale 
  Page 925 - 936Zeitlin PLEditors: Nichols DE, Cameron DE, Greeley WJ, Lappe DG, Ungerleider RM, and Wetzel RC.Mosby, St. Louis, MO1995
• Respiratory Disease in Children 
  Chapter: Pleural effusions and empyema 
  Page 453 - 463Zeitlin PLEditors: Eigen H, and Loughlin GM.Williams and Wilkins, Baltimore, MD1994
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Lectures

• Managing Cystic Fibrosis in Adolescents and Young Adults 
  U. of Nevada, Las Vegas, NV - 1/13/2015
• Cystic Fibrosis 
  Beijing China, 2013; Fort Lauderdale, FL, 2014; Tawam Hospital, Al Ain, UAE, 2014 - 1/9/2014
• Non-invasive Ventilation Workshop 
  Tawam Hospital, Al Ain, U.A.E. - 1/1/2014
• Pro Con Debate: Use of regular thoracic CT and bronchoscopy to care for early CF lung disease 
  San Diego, CA - 1/1/2014
• Dean’s Lecture 
  The Johns Hopkins School of Medicine - 1/13/2013
• Update on Asthma 
  Beijing China - 1/9/2013
• Chronic Cough 
  Yuying Children’s Hospital, Wenzhou, China - 1/31/2011
• Role of UCH-L1 in CFTR Processing 
  Lucerne, Switzerland - 1/21/2010
• Controlling Pseudomonas Aeruginosa Infections: Lessons learned from the cystic fibrosis patient 
  Beijing Children’s Hospital, Beijing, China - 1/11/2009
• Asthma 
  Yuying Children’s Hospital, Wenzhou, China - 1/8/2009
• Targeting CFTR for the Cure 
  Childrens Hospital of LA - 1/6/2009
• Clinical Proteomics: i.e. Cystic Fibr’omics 
  Bethesda, MD - 1/21/2006
• Repair of chloride channel defects in CF 
  University of Pennsylvania - 1/1/2006
• What Should Anesthesiologists Know about Cystic Fibrosis? 
  Geneva, Switzerland - 1/1/2005
• Cystic Fibrosis Management: State of the Art 
  Geneva, Switzerland - 1/1/2005
• Protein Processing and Degradation 
  Cincinnati, OH - 1/26/2004
• Pharmacologic Approaches to CFTR Misfolding 
  Rockville MD - 1/5/2004
• Proteomics for Cystic Fibrosis 
  Paris, France - 1/9/2003
• New Therapies for Cystic Fibrosis 
  Marco Island, FL, 2002; Verona, Italy, 2003 - 1/8/2002
• Update on New Diagnostic Methods and Therapies for Cystic Fibrosis 
  1/12/1999
• Pharmacologic Therapy for Cystic Fibrosis 
  Case Western Reserve University, Cleveland OH - 1/11/1999
• Restoration of chloride transport in Cystic Fibrosis epithelial by sodium 4-phenylbutyrate 
  Jerusalem, Israel - 1/21/1998
• Strategies to Correct the CFTR Defect 
  Paris, France - 1/20/1997
• What's new in Asthma? 
  San Antonio, TX - 1/1/1997
• Phenylbutyrate 
  Williamsburg, VA - 1/1/1997
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