PaulAMeyersMD

PubMed

• Chromoplexy is a frequent early clonal event in EWSR1-rearranged round cell sarcomas that can be detected using clinically validated targeted sequencing panels.
  Healey, J., Vanoli, F., Vanderbilt, C., Dermawan, J., Slotkin, E., Tap, W., Meyers, P., Wexler, L., Antonescu, C.> ;Cancer Research. 2024 Feb 9
• 1 citations
  Irinotecan dose schedule for the treatment of Ewing sarcoma.
  Emily K Slotkin, Paul A Meyers> ;Pediatric Blood & Cancer. 2023 Jan 1
• 11 citations
  Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor
  , , , , , , , , , , , , , , , , , , , , , , > ;Molecular Cancer Research. 2021 Mar 22
• 66 citations
  Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors.
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Nature Cancer. 2021 Feb 15
• 30 citations
  The clinical heterogeneity of round cell sarcomas with EWSR1/FUS gene fusions: Impact of gene fusion type on clinical features and outcome.
  Yusuke Tsuda, Lei Zhang, Paul A. Meyers, William D. Tap, John H. Healey, Cristina R. Antonescu> ;Genes, Chromosomes & Cancer. 2020 Sep 1
• 565 citations
  Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
  Ayuko Hoshino, Han Sang Kim, Linda Bojmar, Kofi Ennu Gyan, Michele Cioffi, Jonathan M. Hernandez, Constantinos P. Zambirinis, Gonçalo Rodrigues, Henrik Molina, Søren H...> ;Cell. 2020 Aug 20
• 19 citations
  Muramyl Tripeptide-Phosphatidyl Ethanolamine Encapsulated in Liposomes (L-MTP-PE) in the Treatment of Osteosarcoma.
  Paul A Meyers> ;Advances in Experimental Medicine and Biology. 2020 Jan 1
• 16 citations
  Ewing sarcoma with FEV gene rearrangements is a rare subset with predilection for extraskeletal locations and aggressive behavior.
  Yusuke Tsuda, Brendan C. Dickson, David Swanson, Yun-Shao Sung, Lei Zhang, Paul A. Meyers, John H. Healey, Cristina R. Antonescu> ;Genes, Chromosomes & Cancer. 2020 May 1
• 35 citations
  DICER1-associated central nervous system sarcoma in children: comprehensive clinicopathologic and genetic analysis of a newly described rare tumor.
  Junne Kamihara, Vera A. Paulson, Micheál Breen, Theodore W. Laetsch, Dinesh Rakheja, David S. Shulman, Michelle Schoettler, Catherine Clinton, Abigail Ward, Deirdre Re...> ;Modern Pathology. 2020 Apr 14
• 16 citations
  Effects of dexrazoxane on doxorubicin-related cardiotoxicity and second malignant neoplasms in children with osteosarcoma: a report from the Children’s Oncology Group
  Lisa M. Kopp, Richard B. Womer, Cindy L. Schwartz, David H. Ebb, Vivian I. Franco, David Hall, Donald A. Barkauskas, Mark Krailo, Holcombe E. Grier, Paul A. Meyers, Le...> ;Cardio-Oncology. 2019 Oct 28
• 11 citations
  Rare BRAF mutations in pancreatic neuroendocrine tumors may predict response to RAF and MEK inhibition.
  Amy Allen, Alice Can Ran Qin, Nitya Raj, Jiawan Wang, Sharmeen Uddin, Zhan Yao, Laura H. Tang, Paul A. Meyers, Barry S. Taylor, Michael F. Berger, Rona Yaeger, Diane R...> ;Plos One. 2019 Jun 3
• 309 citations
  Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort
  Sigbjørn Smeland, Stefan S. Bielack, Jeremy Whelan, Mark L. Bernstein, Pancras C.W. Hogendoorn, Mark Krailo, Richard Gorlick, Katherine A. Janeway, Fiona C. Ingleby, J...> ;European Journal of Cancer. 2019 Mar 1
• 66 citations
  Clinical Genomic Sequencing of Pediatric and Adult Osteosarcoma Reveals Distinct Molecular Subsets with Potentially Targetable Alterations.
  , , , , , , , , , , , , , , , , > ;Clinical Cancer Research. 2019 Jan 1
• 28 citations
  Factors influencing survival after recurrence in osteosarcoma: A report from the Children's Oncology Group.
  Holly Spraker-Perlman, Donald A. Barkauskas, Mark Krailo, Paul A. Meyers, Cindy L. Schwartz, John J. Doski, Richard Gorlick, Katherine A. Janeway, Michael S. Isakoff> ;Pediatric Blood & Cancer. 2019 Jan 1
• 14 citations
  Management of Patients with Acute Methotrexate Nephrotoxicity with High-Dose Leucovorin.
  Carlos D. Flombaum, Dazhi Liu, Shirley Qiong Yan, Amelia Chan, Sherry Mathew, Paul A. Meyers, Ilya G. Glezerman, Thangamani Muthukumar> ;Pharmacotherapy. 2018 Jul 1
• 11 citations
  Unusual abdominal metastases in osteosarcoma.
  Simon Berhe, Enrico Danzer, Paul A. Meyers, Gerald Behr, Michael P. LaQuaglia, Anita P. Price> ;Journal of Pediatric Surgery Case Reports. 2018 Jan 1
• 2 citations
  Intracardiac Low-grade Sarcoma Following Treatment for Ewing Sarcoma.
  Michael V. Ortiz, Heather Magnan, Emily K. Slotkin, Srikanth R. Ambati, Alexander J. Chou, Leonard H. Wexler, Paul A. Meyers, Michael Walsh, Todd E. Heaton, Leonard N....> ;Journal of Pediatric Hematology/oncology. 2017 Nov 1
• 14 citations
  Germline BRCA2 mutations detected in pediatric sequencing studies impact parents' evaluation and care.
  Michael Walsh, Jennifer Kennedy, Megan Harlan, Alex Kentsis, Jacob Musinsky, Stephen S. Roberts, Andrew L. Kung, Mark E. Robson, Brian H. Kushner, Paul A. Meyers, Kenn...> ;Cold Spring Harbor Molecular Case Studies. 2017 Nov 1
• 23 citations
  DNA Methylation–Based Classifier for Accurate Molecular Diagnosis of Bone Sarcomas
  , , , , , , , , , , , , , , , > ;JCO Precision Oncology. 2017 Oct 6
• 41 citations
  Plasma DNA-Based Molecular Diagnosis, Prognostication, and Monitoring of Patients With EWSR1 Fusion-Positive Sarcomas
  Neerav Shukla, Juber Patel, Heather Magnan, Ahmet Zehir, Daoqi You, Jiabin Tang, Fanli Meng, Aliaksandra Samoila, Emily K. Slotkin, Srikanth R. Ambati, Alexander J. Ch...> ;JCO Precision Oncology. 2017 May 23
• 25 citations
  Morbidity and mortality after treatment of Ewing sarcoma: A single-institution experience.
  Danielle Novetsky Friedman, Katherine Chastain, Joanne F. Chou, Chaya S. Moskowitz, Roberto Adsuar, Leonard H. Wexler, Alexander J. Chou, Amelia DeRosa, Joanne Candela...> ;Pediatric Blood & Cancer. 2017 Apr 18
• 24 citations
  A 20-year retrospective analysis of CT-based pre-operative identification of pulmonary metastases in patients with osteosarcoma: A single-center review
  Todd E. Heaton, William J. Hammond, Benjamin A. Farber, Valerie Pallos, Paul A. Meyers, Alexander J. Chou, Anita P. Price, Michael P. LaQuaglia> ;Journal of Pediatric Surgery. 2017 Jan 1
• 1 citations
  Rare presentation of Ewing sarcoma metastasis to the sella and suprasellar cistern.
  Michael T. Starc, Marc K. Rosenblum, Paul A. Meyers, Vaios Hatzoglou> ;Clinical Imaging. 2017 Jan 1
• 11 citations
  A single‐center experience with undifferentiated embryonal sarcoma of the liver
  Melissa Mathias, Srikanth R. Ambati, Alexander J. Chou, Emily K. Slotkin, Leonard H. Wexler, Paul A. Meyers, Heather Magnan> ;Pediatric Blood & Cancer. 2016 Jul 18
• 29 citations
  Assessing the Prognostic Significance of Histologic Response in Osteosarcoma: A Comparison of Outcomes on CCG-782 and INT0133—A Report From the Children's Oncology Gro...
  Michael W. Bishop, Yu Chen Chang, Mark Krailo, Paul A. Meyers, Arthur J. Provisor, Cindy L. Schwartz, Neyssa Marina, Lisa A. Teot, Mark C. Gebhardt, Richard Gorlick, K...> ;Pediatric Blood & Cancer. 2016 Apr 29
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Journal Articles

• Prognostic factors for patients with sarcomas of the pelvic bones.  
  Kawai A, Healey JH, Boland P, Lin PP, Huvos AG, Meyers PA, Cancer 1998; 82:851-9
• EWS-FLI1 Fusion transcript structure is an independent determinant of prognosis in Ewing’s sarcoma.  
  de Alava E, Kawai A, Healey JH, Fligman I, Meyers PA, Huvos AG, Gerald WE, Jhanwar SC, Agrani P, Antonexcu CR, Pardo-Mindan FJ, Ginsberg J, Womer R, Lawlor ER, Wunder ..., J Clin Onc 1998, 16:1248-1255
• Intensification of preoperative chemotherapy for osteogenic sarcoma: The results of the Memorial Sloan-Kettering (T12) protocol.  
  Meyers PA, Gorlick R, Heller G, Casper E, Lane J, Huvos AG Healey JH, J Clin Onc 1998, 16:2452-2458
• Multicentric osteosarcoma, Rothmund-Thomson syndrome and secondary nasopharyngeal non-Hodgkin’s lymphoma. A case report and review of the literature.  
  Spurney C, Gorlick R, Meyers PA, Healey JH, Huvos AG, Am J Ped Hem Onc, 1998, 20:494-7
• Ewing’s sarcoma in a patient with congenital optic atrophy: A case report.  
  Fein-Levy C, Gorlick R, Meyers PA, Healey J, and Huvos AG, Am J Ped Hem Onc, 1998, 20:577-579
• Difficulties completing treatment tasks among newly diagnosed children with cancer.  
  Manne SL, Miller DS, Meyers P, Wollner N, Steinherz P, Redd WH, Children’s Health Care, 1999, 28:255-276
• High risk of leukemia after short-term dose-intensive chemotherapy in young patients with solid tumors.  
  Kushner BH, Heller G, Cheung N-KV, Wollner N, Kramer K, Bajorin D, Polyak T, Meyers PA, J Clin Onc 1998, 16:3016-3020
• The histologic response to chemotherapy as a predictor of the oncological outcome of operative treatment of Ewing’s sarcoma.  
  Wunder JS, Paulian G, Huvos AG, Heller G, Meyers PA, and Healey JH, J Bone Joint Surg, 1998, 80-A:1020-1033
• Malignant vascular tumors in young patients.  
  Lezama-del Valle P, Gerald WL, Tsai J, Meyers P, LaQuaglia MP, Cancer 83:1634-1639
• Mechanisms of methotrexate resistance in osteosarcoma.  
  Guo W, Healey J, Meyers PA, Huvos A, Bertino JR, Gorlick R, Clin Cancer Res, 1999, 5:621-627
• High-dose leucovorin as sole therapy for methotrexate toxicity.  
  Flombaum CD and Meyers PA, J Clin Onc, 1999, 17:1589-1594
• Expression of HER2/ErbB-2 correlates with survival in osteosarcoma.  
  Gorlick R, Huvos AG, Heller G, Aledo A, Beardsley GP, Healey JH, Meyers PA, J Clin Onc, 1999, 17:2781-8
• Osteosarcoma associated with absent thumbs: A report of two cases.  
  Orme L, Gorlick R, Meyers PA, Athanasian E, Huvos AG, Am J Ped Hem Onc, 1999, 22:73-77
• Expression of bone morphogenetic proteins and receptors in sarcomas.  
  Meyers PA, Huvos AG, Bertino JR, Healey JH, Clin Orthop Relat Res. 1999 Aug;(365):175-83
• Ewing’s sarcoma of the rib: Results of an intergroup study with analysis of outcome by timing of resection.  
  Shamberger RD, LaQuaglia MP, Krailo MD, Miser JS, Pritchard DJ, Gebhardt MC, Healey JH, Tarbell NJ, Fryer CJH, Meyers PA, Grier HE, J Thoracic and Cardiovascular Surg, 2000, 119:1154-1161
• Expression of genes encoding bone morphogenetic proteins and their receptors in sarcomas.  
  Guo W, Gorlick R, Ladanyi M. Meyers PA, Huvos AG, Bertino JR, Healey JH, Clin Orthop Related Res, 1999, 365:175-83
• Ewing’s sarcoma/primitive neuroectodermal tumor of the ureter: a case report and review of the literature.  
  Charny CK, Glick RD, Genega EM, Meyers PA, Reuter VE, LaQuaglia MP, J Pediatr Surg 2000, 35:1356-1358
• Pediatric chest wall Ewing's sarcoma.  
  Saenz NC, Hass DJ, Meyers P, Wollner N, Gollamudi S, Bains M, LaQuaglia MP, J Pediatr Surg. 2000 Apr;35(4):550-555
• Prognostic impact of INK4A deletion in Ewing sarcoma.  
  Wei G, Antonescu CR, de Alava E, Leung D, Huvos AG, Meyers PA, Healey JH, Ladanyi M, Cancer 2000, 89:793-799
• Prognostic impact of p53 status in Ewing sarcoma.  
  de Alava E, Antonescu CR, Panizo A, Leung D, Meyers PA, Huvos AG, Pardo-Mindan FJ, Healey JH, Ladanyi M, Cancer 2000, 89:783-792
• How effective is dose-intensive /myeloablative therapy against peripheral primitive neuroectodermal tumors (including Ewing’s sarcoma) metastatic to bone or bone marro...  
  Kushner BH, Meyers PA, J Clin Oncol 2001, 19:870-880
• Pilot study of topotecan and high dose cyclophosphamide for resistant pediatric solid tumors.  
  Kushner BH, Kramer K, Meyers PA, Wollner N, Cheung N-KV, Med Pediatr Oncol 2000, 35:468-474
• Immediate free flap mandibular reconstruction in osteosarcoma of the mandible in childhood.  
  Lydaki E, Bolonaki I, Stiakaki E, Kambourakis A, Cordeiro PB, Meyers PA, Delides G, Hatzimanolis P, Kalmanti M, Pediatr Hematol Oncol. 2000 Jun;17(4):335-40
• High dose melphalan, etoposide, total body irradiation and autologous stem cell reconstitution as consolidation therapy for Ewing's sarcoma metastatic to bone or bone ...  
  Meyers PA, Krailo MD, Ladanyi M, Chan K-W, Sailer SL, Dickman PS, Baker DL, Davis JH, Gerbing RB, Grovas A, Herzog CE, Lindsley KL, Liu-Mares W, Nachman JB, Sieger L, ..., J Clin Oncol, 2001, 19:2812-2820
• Human epidermal growth factor receptor 2 as a prognostic indicator in osteogenic sarcoma.  
  Morris CD, Gorlick R, Huvos G, Heller G, Meyers PA, Healey JH, Clin Orthop. 2001 Jan;(382):59-65
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Books/Book Chapters

• Chelation Therapy in Chronic Iron Overload. 
  Chapter: Continuous intravenous and sub-cutaneous deferrioxamine therapy in beta thalassemia major 
  Page 115 - 125Markenson AL, Graziano JH, Miller DR, Chang H, Bestak M, Meyers P, Pisciotta P, Rifkind AEditors: EC Zaino and RH Roberts. Symposia Specialists Inc
• Hemoglobins in Development and Differentiation. 
  Chapter: Activation of fetal hemoglobin synthesis in cultured adult bone marrow 
  Page 389 - 395Meyers PA, Integlia B, Kapoor N, and Moore MASEditors: Stamatoyannopoulos G and Nienhuis AW.Liss, New York
• Blood Diseases of Infancy and Childhod. 
  Chapter: Megaloblastic anemias 
  Page 147 - 170Meyers PA and Miller DREditors: Miller DR, Baehner RL, McMillian C.CV Mosby, St. LouisEdition 5,
• Hematology-Oncology Clinics of North America. 
  Chapter: Ewing’s sarcoma 
  Page 667 - 673Meyers PAEditors: Pochedly CA.WB Saunders, Philadelphia
• Hematology-Oncology Clinics of North America. 
  Chapter: Osteogenic sarcoma 
  Page 655 - 665Meyers PAEditors: Pochedly CA.WB Saunders, Philadelphia
• Blood Diseases of Infancy and Childhood. 
  Chapter: Megaloblastic anemia 
  Page 199 - 220Meyers PAEditors: Miller DR and Baehner RL.CV Mosby
• Acute Lymphoblastic Leukemia: Current Controversies and Future Direction.. 
  Chapter: Improved survival of children with high-risk lymphoblastic leukemia: Report from the children’s cancer study and the Memorial Sloan-Kettering “New York” protocols 
  Page 1437 - 1456Steinherz PG, Gaynon P, Haimi J, Meyers P, Redner A, Steinherz L, Andreeff M, Hammond DEditors: Gale RP, Hoelzer D.Wiley-Liss, New York
• Birth Defects Encyclopedia. 
  Chapter: Transcobalamin II deficiency 
  Page 1693 - 1694Meyers PAEditors: Buyse ML.Blackwell Scientific Publications, Cambridge MA
• Birth Defects Encyclopedia. 
  Chapter: Anemia, pernicious congenital 
  Meyers PAEditors: Buyse ML.Blackwell Scientific Publications, Cambridge MA
• Blood Diseases of Infancy and Childhood. 
  Chapter: Megaloblastic anemias 
  Page 220 - 240Kamen BA and Meyers PAEditors: Miller DR and Baehner RL.CV Mosby
• Osteosarcoma in Pediatric Clinics of North America. 
  Page 973 - 989Meyers PA and Gorlick RWB Saunders, Philadelphia
• Saunders Manual of Pediatric Practice. 
  Chapter: Section editor, Hematology/Oncology 
  Page 373 - 492Meyers PAEditors: Finberg L.WB Saunders
• Saunders Manual of Pediatric Practice. 
  Chapter: Osteosarcoma 
  Page 480 - 482Meyers PAEditors: Finberg L.WB Saunders
• Saunders Manual of Pediatric Practice. 
  Chapter: Ewing’s Sarcoma 
  Page 482 - 484Meyers PAEditors: Finberg L.WB Saunders
• Priniciples and Practice of Pediatric Oncology. 
  Chapter: Osteosarcoma 
  Link MP, Meyers PA, Gebhardt MEditors: Pizzo PA, Poplack DG.Lippincott, Williams, & Wilkins, PhiladelphiaEdition 4,
• Therapy of Cancer in Children. 
  Chapter: Osteosarcoma and Ewing’s Sarcoma 
  Meyers PAEditors: Pratt C, Herzog C.Clinical Insights, New York
• Current Treatment Options in Oncology. 
  Chapter: Ewing’s Sarcoma 
  Meyers PA, Levy AS
• Acute Lymphoblastic Leukemia: Current Controversies and Future Direction. 
  Chapter: Improved survival of children with high-risk lymphoblastic leukemia: Report from the Children's Cancer Study and the Memorial Sloan-Kettering "New York" protocols 
  Page 147 - 156Steinherz PG, Gaynon P, Haimi J, Meyers P, Redner A, Steinherz L, Andreeff M, Hammond DEditors: R.P. Gale, D. Hoelzer.Wiley-Liss, New York
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Lectures

• The addition of cycles of irinotecan/temozolomide (i/T) to cycles of vincristine, doxorubicin, cyclophosphamide (VDC) and cycles of ifosfamide, etoposide (IE) for the ... 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/2/2018

Other

• High dose therapy with autologous stem cell rescue for pediatric sarcomas. 
  Meyers PA, ASCO Education Book
• Holcombe Grier Faculty of 1000 Medicine: evaluations for Meyers PA et al. 
  Paul A. Meyers, Cindy Schwartz, Mark Krailo, Eugenie Kleinerman, Donna Betcher, William Ferguson, Mark Gebhardt, Allen Goorin, Helen Nadel, Michael Nieder, Gene Sigel,..., J Clin Oncol 2008 Feb 1 26 (4) :633-8
  http://www.f1000medicine.com/article/id/1100377/evaluation
• Response to Osteosarcoma: Time to Move On? 
  Meyers PA, Kleinerman E, European Journal of Cancer
  http://www.ecco-org.eu/News/News/EJC-Correspondence/Latest-Correspondence/Osteosarcoma-Time-to-move-