RaymondLBenzaMDFACC, FAHA, FCCP

Cardiology • Westbury, NY

Heart Failure & Transplantation

Professor of Medicine Chief Medical Officer PHope

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Office
695 Merrick Ave
Westbury, NY 11590
Phone+1 412-304-8866

Fax+1 614-293-5614
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Summary

Dr. Raymond Benza is a cardiologist in New York and is the CMO of PHope, a company founded to bring new interventional therapies for pulmonary hypertension. He received his medical degree from University of Florida College of Medicine. He specializes in heart failure, transplantation, mechanical circulatory support and pulmonary vascular diseases. His research is funded by the NIH.

Education & Training

University of Alabama Medical CenterChief Residency, Cardiovascular Disease, 1996 - 1997
University of Alabama Medical CenterFellowship, Cardiovascular Disease, 1993 - 1996
University of Michigan Health SystemResidency, Internal Medicine, 1990 - 1992
University of Michigan Health SystemInternship, Internal Medicine, 1989 - 1990
University of Florida College of MedicineClass of 1989

Certifications & Licensure

NY State Medical License 1992 - 2025
OH State Medical License 2020 - 2024
PA State Medical License 2008 - 2021
AL State Medical License 1993 - 2008
MI State Medical License 1991 - 1995
American Board of Internal Medicine Advanced Heart Failure and Transplant Cardiology

Awards, Honors, & Recognition

Association of University Cardiologists 2021
Bob and Corrine Endowed Chair of Heart Failure The Ohio State University, 2020
Best Doctors Pittsburgh 2013-2020
Pittsburgh Health Care Hero Pittsburgh Business Times, 2015, 2019
Fellow american college of chest physicians, 2015
Regional Top Doctor Castle Connolly, 2013-2015
Physician of the Year Pulmonary Hypertension Association, 2012
CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2012-2013
Knight, Order of Maurice and Lasarus Royal Order of Savoy, Savoy Italy, 2011
James Magovern Chair for Cardiovascular Research Allegheny Singer Research Institute, 2008
Fellow American Heart Association
Fellow (FACC) American College of Cardiology
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Clinical Trials

REVEAL Registry™: Registry to Evaluate Early And Long-term PAH Disease Management Start of enrollment: 2006 Mar 01
Completed
Safety and Efficacy Study of Ambrisentan in Subjects With Pulmonary Hypertension Start of enrollment: 2006 Aug 01
Completed
Phase 3
Pharmacogenomics in Pulmonary Arterial Hypertension Start of enrollment: 2005 Jul 01
Withdrawn
Effects of Remote Patient Monitoring on Heart Failure Management Start of enrollment: 2009 Mar 01
Completed
Not Applicable
Study in Subjects With PAH and PH Secondary to IPF Using Inhaled GeNOsyl. Start of enrollment: 2011 Mar 01
Completed
Phase 2
Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies Start of enrollment: 2010 Dec 01
Completed
Inhaled Nitric Oxide/INOpulse DS for Pulmonary Arterial Hypertension (PAH) Start of enrollment: 2012 Apr 01
Completed
Phase 2
Clinical Study to Evaluate the Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) Due to Left Ventricular Dysfunction Start of enrollment: 2014 Jul 01
Completed
Phase 2
Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH Start of enrollment: 2016 Apr 01
Completed
Phase 2
A Study to Assess the Safety, Tolerability, and Hemodynamic Response of PB1046 in Subjects With PAH Start of enrollment: 2017 Oct 20
Completed
Phase 1
Telemonitoring to Treat Group 2 Pulmonary Hypertension Start of enrollment: 2023 Apr 01
Not yet recruiting
Phase 2
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

The heart of the matter: Right heart imaging indicators for treatment escalation in pulmonary arterial hypertension.
Paul Forfia, Raymond Benza, Michele D'Alto, Teresa De Marco, Jean M Elwing, Robert Frantz, Francois Haddad, Ronald Oudiz, Ioana R Preston, Stephan Rosenkranz, John Rya...> ;Pulmonary Circulation. 2023 Apr 1
Treatment effects of pulmonary artery denervation for pulmonary arterial hypertension stratified by REVEAL risk score: Results from PADN-CFDA trial.
Juan Zhang, Jing Kan, Yongyue Wei, Caojin Zhang, Zhenwen Yang, Heping Gu, Fenling Fan, Hong Gu, Qiguang Wang, Dujiang Xie, Gangcheng Zhang, Xiaomei Guo, Yuehui Yin, Bo...> ;The Journal of Heart and Lung Transplantation. 2023 Aug 1
1 citations
European Society of Cardiology quality indicators for the care and outcomes of adults with pulmonary arterial hypertension. Developed in collaboration with the Heart F...
Suleman Aktaa, Chris P Gale, Margarita Brida, George Giannakoulas, Gabor Kovacs, Yochai Adir, Raymond L Benza, Michael Böhm, Andrew Coats, Michele D'Alto, Pilar Escrib...> ;European Journal of Heart Failure. 2023 Apr 1
1 citations
Smoking history and pulmonary arterial hypertension: Demographics, onset, and outcomes.
Adaani E Frost, Carol Zhao, Harrison W Farber, Raymond Benza, Joseph Yen, Mona Selej, C Gregory Elliott> ;The Journal of Heart and Lung Transplantation. 2023 Mar 1
1 citations
Pulmonary artery compliance in different forms of pulmonary hypertension.
Amber McCormick, Amita Krishnan, David Badesch, Raymond L Benza, Todd M Bull, Teresa De Marco, Jeremy Feldman, Anna R Hemnes, Russel Hirsch, Evelyn Horn, Jaime Kennedy...> ;Heart. 2023 Jun 26
2 citations
Derivation of a Risk Score (REVEAL-ECHO) Based on Echocardiographic Parameters of Patients With Pulmonary Arterial Hypertension.
Karim El-Kersh, Carol Zhao, Gregory Elliott, Harrison W Farber, Mardi Gomberg-Maitland, Mona Selej, Josephine Garcia-Ferrer, Raymond Benza> ;Chest. 2023 May 1
1 citations
Riociguat and the right ventricle in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
Raymond L Benza, David Langleben, Anna R Hemnes, Anton Vonk Noordegraaf, Stephan Rosenkranz, Thenappan Thenappan, Paul M Hassoun, Ioana R Preston, Stefano Ghio, Robert...> ;European Respiratory Review. 2022 Dec 31
1 citations
Safety and efficacy of RT234 vardenafil inhalation powder on exercise parameters in pulmonary arterial hypertension: phase II, dose-escalation study design.
Raymond L Benza, Veronica Franco, Mandar A Aras, Leslie Spikes, Daniel Grinnan, Carol Satler> ;Respiratory Research. 2022 Dec 17
Prognostic role of pulmonary hemodynamics before transcatheter aortic valve replacement among patients with severe aortic stenosis.
Garima Dahiya, Andreas Kyvernitakis, Adee Elhamdani, Andrew Begg, Mark Doyle, Mahmoud Elsayed, Stephen Bailey, Amresh Raina, Manreet Kanwar, Robert W W Biederman, Raym...> ;The Journal of Heart and Lung Transplantation. 2023 Feb 1
Phenotypes of idiopathic pulmonary arterial hypertension.
Roberto Badagliacca, Raymond L Benza, Giovanna Manzi, Khodr Tello, Robert Naeije> ;The Lancet. Respiratory Medicine. 2022 Oct 1
5 citations
ISHLT consensus statement: Perioperative management of patients with pulmonary hypertension and right heart failure undergoing surgery.
Dana P McGlothlin, John Granton, Walter Klepetko, Maurice Beghetti, Erika B Rosenzweig, Paul A Corris, Evelyn Horn, Manreet K Kanwar, Karen McRae, Antonio Roman, Ryan ...> ;The Journal of Heart and Lung Transplantation. 2022 Sep 1
2 citations
Plasma Cell-Free DNA Predicts Survival and Maps Specific Sources of Injury in Pulmonary Arterial Hypertension.
Samuel B Brusca, Jason M Elinoff, Yvette Zou, Moon Kyoo Jang, Hyesik Kong, Cumhur Y Demirkale, Junfeng Sun, Fayaz Seifuddin, Mehdi Pirooznia, Hannah A Valantine, Carl ...> ;Circulation. 2022 Oct 4
3 citations
Contemporary risk scores predict clinical worsening in pulmonary arterial hypertension - An analysis of FREEDOM-EV.
Raymond L Benza, Mardi Gomberg-Maitland, Harrison W Farber, Carmine Dario Vizza, Meredith Broderick, Louis Holdstock, Andrew C Nelsen, Chunqin Deng, Youlan Rao, R Jame...> ;The Journal of Heart and Lung Transplantation. 2022 Nov 1
1 citations
INSPIRE: Safety and tolerability of inhaled Yutrepia (treprostinil) in pulmonary arterial hypertension (PAH).
Nicholas S Hill, Jeremy P Feldman, Sandeep Sahay, Raymond L Benza, Ioana R Preston, David Badesch, Robert P Frantz, Savan Patel, Ashley Galloway, Todd M Bull> ;Pulmonary Circulation. 2022 Jul 1
2 citations
Prediction of patient outcomes through social determinants of health: The Pulmonary Hypertension Association Registry (PHAR) evaluation.
Dan Grinnan, Le Kang, Christine DeWilde, David Badesch, Raymond Benza, Todd Bull, Murali Chakinala, Teresa DeMarco, Jeremy Feldman, Hubert J Ford, James Klinger, John ...> ;Pulmonary Circulation. 2022 Jul 1
Two polymorphic gene loci associated with treprostinil dose in pulmonary arterial hypertension.
Vasiliki Thomeas-McEwing, Mitchell A Psotka, Eric R Gamazon, Paula Friedman, Anuar Konkashbaev, Michiaki Kubo, Yusuke Nakamura, Mark J Ratain, Raymond L Benza, Nancy J...> ;Pharmacogenetics and Genomics. 2022 Jun 1
1 citations
Maternal and fetal outcomes in pregnant women with pulmonary hypertension: The impact of left heart disease.
William H Marshall, Stephen Gee, Woobeen Lim, Lauren T Lastinger, Michael Cackovic, Raymond L Benza, Curt J Daniels, Elisa A Bradley, Saurabh Rajpal> ;International Journal of Cardiology. Congenital Heart Disease. 2022 Jun 1
14 citations
Aggressive Afterload Lowering to Improve the Right Ventricle: A New Target for Medical Therapy in Pulmonary Arterial Hypertension?
Carmine Dario Vizza, Irene M Lang, Roberto Badagliacca, Raymond L Benza, Stephan Rosenkranz, R James White, Yochai Adir, Arne K Andreassen, Vijay Balasubramanian, Sonj...> ;American Journal of Respiratory and Critical Care Medicine. 2022 Apr 1
Application of the REVEAL risk score calculator 2.0 in the CHEST study.
Raymond L Benza, Harrison W Farber, Adaani E Frost, Hossein-Ardeschir Ghofrani, Paul A Corris, Marc Lambelet, Sylvia Nikkho, Christian Meier, Marius M Hoeper> ;Respiratory Medicine. 2022 Mar 1
1 citations
Computational Simulator Models and Invasive Hemodynamic Monitoring as Tools for Precision Medicine in Pulmonary Arterial Hypertension.
Giovanna Manzi, Cristiano Miotti, Marco Valerio Mariani, Silvia Papa, Federico Luongo, Gianmarco Scoccia, Beatrice De Lazzari, Claudio De Lazzari, Raymond L Benza, Fra...> ;Journal of Clinical Medicine. 2021 Dec 24
3 citations
Change in REVEAL Lite 2 risk score predicts outcomes in patients with pulmonary arterial hypertension in the PATENT study.
Raymond L. Benza, Athénaïs Boucly, Harrison W. Farber, Adaani E. Frost, Hossein Ardeschir Ghofrani, Marius M. Hoeper, Marc Lambelet, Claudia Rahner, Sameer Bansilal, S...> ;The Journal of Heart and Lung Transplantation. 2021 Oct 28
12 citations
TORREY, a Phase 2 study to evaluate the efficacy and safety of inhaled seralutinib for the treatment of pulmonary arterial hypertension.
Robert P. Frantz, Raymond L. Benza, Richard N. Channick, Kelly Chin, Luke Howard, Vallerie V. McLaughlin, Olivier Sitbon, Roham T. Zamanian, Anna R. Hemnes, Matt Crave...> ;Pulmonary Circulation. 2021 Oct 22
20 citations
Evaluation and management of patients with chronic thromboembolic pulmonary hypertension - consensus statement from the ISHLT.
Marc de Perrot, Deepa Gopalan, David P. Jenkins, Irene M. Lang, Elie Fadel, Marion Delcroix, Raymond L. Benza, Gustavo A. Heresi, Manreet Kanwar, John Granton, Micheal...> ;The Journal of Heart and Lung Transplantation. 2021 Aug 3
14 citations
Early toxicity and clinical outcomes after chimeric antigen receptor T-cell (CAR-T) therapy for lymphoma.
Jonathan E. Brammer, Zachary Braunstein, Aashish Katapadi, Kyle Porter, Michael Biersmith, Avirup Guha, Sumithira Vasu, Vedat O. Yildiz, Sakima A. Smith, Benjamin Buck...> ;Journal for Immunotherapy of Cancer. 2021 Aug 1
4 citations
Effect of riociguat on right ventricular function in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension
Raymond L. Benza, Hossein Ardeschir Ghofrani, Ekkehard Grünig, Marius M. Hoeper, Pavel Jansa, Zhi-Cheng Jing, Nick H. Kim, David Langleben, Gérald Simonneau, Chen Wang...> ;The Journal of Heart and Lung Transplantation. 2021 Jul 10
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Journal Articles

Clinical Research A Bayesian Model to Predict Survival After Left Ventricular Assist Device Implantation
Stephen H Bailey, Srinivas Murali, Joseph G Rogers, Raymond Benza, Jeffrey J Teuteberg, Colleen K McIlvennan, Robert L Kormos, JoAnn Lindenfeld, ScienceDirect

Lectures

Highlighted Original Research: Pulmonary Hypertension and Venous Thrombo-Embolic Disease and the Year in Review
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019

Press Mentions

OSU Wexner Launches 'Hospital-at-Home' Program for Patients with Heart FailureJanuary 28th, 2022
WellSky® to Deliver in-Home Protocols for Patients with Heart FailureJanuary 27th, 2022
United Therapeutics Details New Data Presented at CHEST Annual Meeting 2021October 21st, 2021
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Grant Support

VITA: Vascular Interventions/Innovations and Therapeutic AdvancesNational Heart, Lung and Blood Institute2014–Present
Salivary Gland-Based Gene Therapy for Pulmonary Arterial HypertensionNational Heart, Lung and Blood Institute2013–Present
Pulmonary Hypertension Breakthrough InitiativeAmerican Heart Association2008–Present
Pharmacogenomics In Pulmonary Arterial HypertensionNational Heart, Lung, And Blood Institute2008
Pharmacogenomics In Pulmonary Arterial HypertensionNational Heart, Lung, And Blood Institute2005–2007
Genetic Determination Of Allograft VasculopathyNational Heart, Lung, And Blood Institute1998–2002