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Office
1959 NE Pacific St, Box 356320
Seattle, WA 98195Phone+1 206-221-6814- Is this information wrong?
Summary
- Dr. Sandra ”Sunny” Juul, MD, PhD is Division Chief of Neonatology at Seattle Children’s Hospital and the University of Washington. After completing her medical degree, residency, fellowship and two years as an acting Assistant Professor at the University of Washington, Dr. Juul left Seattle in 1991 for the University of Chicago where she began a Ph.D. in Developmental Biology. She then joined the faculty at the University of Florida in 1993, where her Ph.D. work was completed. In 2000, Dr. Juul was successfully recruited back to Seattle. She is board certified in Pediatrics and Neonatology.
Dr. Juul leads a translational neonatal neuroscience research program. The focus is to identify new therapeutic approaches to neonatal brain injury, determine whether they are safe and effective, and if so, bring these new treatments from the laboratory to the bedside. Dr. Juul identified Epo and its receptor in the developing human brain, demonstrated that it is neuroprotective and safe using multiple animal models of neonatal brain injury. Bringing this work from the bench to the bedside, Dr. Juul is currently Principal Investigator of a multicenter randomized controlled trial to determine whether Epo is a safe and effective neuroprotectant for extremely preterm infants. The study, Preterm Epo Neuroprotection (PENUT) is funded by NINDS, and has enrolled 940 babies born between 24-0/7 and 26-6/7 weeks of gestation. These children are currently being followed to two years of age for detailed neurodevelopmental assessments. Dr. Juul is also multi-PI with Dr. Yvonne Wu (UCSF) on the High-Dose Erythropoietin for Asphyxia and Encephalopathy (HEAL) Trial, a randomized controlled trial of Epo neuroprotection for 500 term infants with hypoxic-ischemic encephalopathy (HIE). This multicenter trial will determine whether Epo in addition to therapeutic cooling will improve the outcome for infants with HIE.
Education & Training
- University of ChicagoPhD, Developmental Biology, 1991 - 1997
- University of WashingtonFellowship, Neonatal-Perinatal Medicine, 1986 - 1989
- University of WashingtonChief Residency, Pediatrics, 1985 - 1986
- University of WashingtonResidency, Pediatrics, 1981 - 1984
- University of Washington School of MedicineClass of 1981
Certifications & Licensure
- WA State Medical License 1982 - 2026
- FL State Medical License 1993 - 2002
- IL State Medical License 1991 - 1993
- American Board of Pediatrics Pediatrics
- American Board of Pediatrics Neonatal-Perinatal Medicine
Awards, Honors, & Recognition
- Fellow (FAAP) American Academy of Pediatrics
Clinical Trials
- Preterm Erythropoietin Neuroprotection Trial (PENUT Trial) Start of enrollment: 2013 Dec 01
- Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes in Newborn Brain Injury (NEATO) Start of enrollment: 2013 Sep 01
- High-dose Erythropoietin for Asphyxia and Encephalopathy Start of enrollment: 2017 Jan 01
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Publications & Presentations
PubMed
- Relationship of Neonatal Seizure Burden Before Treatment and Response to Initial Antiseizure Medication.Adam L Numis, Hannah C Glass, Bryan A Comstock, Fernando Gonzalez, Nathalie L Maitre, Shavonne L Massey, Dennis E Mayock, Ulrike Mietzsch, Niranjana Natarajan, Gregory...> ;The Journal of Pediatrics. 2024 May 1
- Esophageal Versus Rectal Temperature Monitoring During Whole-Body Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy: Association with Short- and Long-Term Ou...Tai-Wei Wu, Robert Schmicker, Thomas R Wood, Ulrike Mietzsch, Bryan Comstock, Patrick J Heagerty, Rakesh Rao, Fernando Gonzalez, Sandra Juul, Yvonne W Wu> ;The Journal of Pediatrics. 2024 May 1
- 1 citationsContemporary definitions of infant growth failure and neurodevelopmental and behavioral outcomes in extremely premature infants at two years of age.Strobel, K., Wood, T., Hendrixson, D., Law, J., Comstock, B., Heagerty, P., Valentine, G., German, K., Gogcu, S., Kolnik, S., Mayock, D., Juul, S.> ;Journal of Perinatology. 2024 Jan 9
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Journal Articles
- Effect of High-Dose Erythropoietin on Blood Transfusions in Extremely Low Gestational Age NeonatesSandra E Juul, Dennis E Mayock, Kaashif A Ahmad, Ellen Bendel-Stenzel, Mariana Baserga, Edmund F Lagamma, Nancy Fahim, Andrea Lampland, Ivan D Frantz, Janine Khan, Mau..., JAMA Pediatrics
- A Randomized Trial of Erythropoietin for Neuroprotection in Preterm InfantsSandra Juul, MD, The New England Journal of Medicine
Authored Content
- Effect of High-Dose Erythropoietin on Blood Transfusions in Extremely Low Gestational Age NeonatesAugust 2020
- Effect of High-Dose Erythropoietin on Blood Transfusions in Extremely Low Gestational Age NeonatesAugust 2020
Grant Support
- Optimizing Neuroprotection Following Perinatal AsphyxiaNational Center For Research Resources2010–2011
- Optimizing Neuroprotection Following Perinatal AsphyxiaEunice Kennedy Shriver National Institute Of Child Health &Human Development2007–2011
- EPO Neuroprotection Of ELBW Infants: Planning GrantNational Institute Of Neurological Disorders And Stroke2010
- Optimizing Neuroprotection Following Neonatal Hypoxic-Ischemic Brain InjuryNational Center For Research Resources2009
- Safety &Efficacy Of R-Erythropoietin As A Rescue AgentNational Center For Research Resources2006
- Safety And Efficacy Of Recombinant Erythropoietin (REPO) As A Rescue Agent For ANational Center For Research Resources2004–2005
- Pharmacokinetics Of Erythropoietin In The CSF Of Macaques NemestrinaNational Center For Research Resources2004–2005
- Optimizing Iron Status In The Preterm NeonateNational Center For Research Resources2004–2005
- EPO As A Rescue Agent For Perinatal Hypoxia-IschemiaEunice Kennedy Shriver National Institute Of Child Health &Human Development2002–2004
- Nonhematopoietic Developmental Functions Of EPOEunice Kennedy Shriver National Institute Of Child Health &Human Development2001–2004
- Idiopathic Neutropenia In NeonatesNational Center For Research Resources1999–2001
- Nonhematopoietic Development Function Of ErythropoietinNational Center For Research Resources2000
- Erythropoietin Concentration In Human MilkNational Center For Research Resources2000
- Effect Of Meningitis Intraventricular Hemorrhage And Birth AsphyxiaNational Center For Research Resources1998–2000
Professional Memberships
- Fellow
Hospital Affiliations
- UW Medicine/University of Washington Medical CenterSeattle, Washington
- Seattle Children's HospitalSeattle, Washington
External Links
- University of Washingtonhttps://www.uwmedicine.org/bios/sandra-juul-ledbetter
- Seattle Children's Hospitalhttp://www.seattlechildrens.org/medical-staff/sandra-e-juul/
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