
Sandra E Juul MD PhD
Neonatal Neurodevelopment
Professor of Pediatrics
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1959 NE Pacific St, Box 356320Seattle, WA 98195
Phone+1 206-221-6814
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Summary
- Dr. Sandra ”Sunny” Juul, MD, PhD is Division Chief of Neonatology at Seattle Children’s Hospital and the University of Washington. After completing her medical degree, residency, fellowship and two years as an acting Assistant Professor at the University of Washington, Dr. Juul left Seattle in 1991 for the University of Chicago where she began a Ph.D. in Developmental Biology. She then joined the faculty at the University of Florida in 1993, where her Ph.D. work was completed. In 2000, Dr. Juul was successfully recruited back to Seattle. She is board certified in Pediatrics and Neonatology.
Dr. Juul leads a translational neonatal neuroscience research program. The focus is to identify new therapeutic approaches to neonatal brain injury, determine whether they are safe and effective, and if so, bring these new treatments from the laboratory to the bedside. Dr. Juul identified Epo and its receptor in the developing human brain, demonstrated that it is neuroprotective and safe using multiple animal models of neonatal brain injury. Bringing this work from the bench to the bedside, Dr. Juul is currently Principal Investigator of a multicenter randomized controlled trial to determine whether Epo is a safe and effective neuroprotectant for extremely preterm infants. The study, Preterm Epo Neuroprotection (PENUT) is funded by NINDS, and has enrolled 940 babies born between 24-0/7 and 26-6/7 weeks of gestation. These children are currently being followed to two years of age for detailed neurodevelopmental assessments. Dr. Juul is also multi-PI with Dr. Yvonne Wu (UCSF) on the High-Dose Erythropoietin for Asphyxia and Encephalopathy (HEAL) Trial, a randomized controlled trial of Epo neuroprotection for 500 term infants with hypoxic-ischemic encephalopathy (HIE). This multicenter trial will determine whether Epo in addition to therapeutic cooling will improve the outcome for infants with HIE.
Education & Training
University of ChicagoPhD, Developmental Biology, 1991 - 1997
University of WashingtonFellowship, Neonatal-Perinatal Medicine, 1986 - 1989
University of WashingtonChief Residency, Pediatrics, 1985 - 1986
University of WashingtonResidency, Pediatrics, 1981 - 1984
University of Washington School of MedicineClass of 1981
Certifications & Licensure
WA State Medical License 1982 - 2028
FL State Medical License 1993 - 2002
IL State Medical License 1991 - 1993
American Board of Pediatrics Pediatrics
American Board of Pediatrics Neonatal-Perinatal Medicine
Awards, Honors, & Recognition
- Fellow (FAAP) American Academy of Pediatrics
Clinical Trials
- Preterm Erythropoietin Neuroprotection Trial (PENUT Trial) Start of enrollment: 2013 Dec 01
- Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes in Newborn Brain Injury (NEATO) Start of enrollment: 2013 Sep 01
- High-dose Erythropoietin for Asphyxia and Encephalopathy Start of enrollment: 2017 Jan 01
Publications & Presentations
PubMed
- Acceptability and Feasibility of an Educational Intervention to Improve Researcher-Participant Interactions in a Neonatal Intensive Care Unit Clinical Trial: Research ...Stephanie A Kraft, Devan M Duenas, Andrea Kelsh, Ellie Oslin, Megan M Gray
American Journal of Perinatology. 2026-03-11 - Multi-modal screening for synergistic neuroprotection of mild extremely preterm brain injury.Zheyu Ruby Jin, Kylie A Corry, Olivia C Brandon, Matthew J Magoon, Hawley Helmbrecht
Bioengineering & Translational Medicine. 2026-03-01 - 1 citationsYoga in the NICU for Parents: A Pilot Study on Reducing Stress in the NICU.Sara K Neches, Alanna Feltner, Mihai Puia-Dumitrescu, Krystle Perez, Leanne Matullo
American Journal of Perinatology. 2026-03-01
Journal Articles
- Effect of High-Dose Erythropoietin on Blood Transfusions in Extremely Low Gestational Age NeonatesSandra E Juul, Dennis E Mayock, Kaashif A Ahmad, Ellen Bendel-Stenzel, Mariana Baserga, Edmund F Lagamma, Nancy Fahim, Andrea Lampland, Ivan D Frantz, Janine Khan, Mau..., JAMA Pediatrics
- A Randomized Trial of Erythropoietin for Neuroprotection in Preterm InfantsSandra Juul, MD, The New England Journal of Medicine
Authored Content
- Effect of High-Dose Erythropoietin on Blood Transfusions in Extremely Low Gestational Age NeonatesAugust 2020
- Effect of High-Dose Erythropoietin on Blood Transfusions in Extremely Low Gestational Age NeonatesAugust 2020
Grant Support
- Trial of Darbepoetin plus slow-release intravenous iron to decrease transfusions and improve iron status and neurodevelopment in preterm infantsUNIVERSITY OF WASHINGTON2022–2027
- Intellectual and Developmental Disabilities Research CenterUNIVERSITY OF WASHINGTON2025–2026
- 14th Hershey Developmental Brain Injury ConferenceUNIVERSITY OF WASHINGTON2024–2025
- Optimizing Neuroprotection Following Perinatal AsphyxiaNational Center For Research Resources2010–2011
- Optimizing Neuroprotection Following Perinatal AsphyxiaEunice Kennedy Shriver National Institute Of Child Health &Human Development2007–2011
Professional Memberships
- Fellow
External Links
- University of Washingtonhttps://www.uwmedicine.org/bios/sandra-juul-ledbetter
- Seattle Children's Hospitalhttp://www.seattlechildrens.org/medical-staff/sandra-e-juul/
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