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Simon Robson, MD, Gastroenterology, Boston, MA, Beth Israel Lahey Health

Simon C. Robson MD PhD, FAASLD (He/Him)

Gastrointestinal Cancer, Hepatology & Liver Transplantation, Inflammatory Bowel Disease


Professor, Medicine and Anesthesiology, Vice Chair Research, Beth Israel Deaconess Medical Center, Harvard Medical School

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  • 330 Brookline AvenueBeth Israel Deaconess Medical CenterBoston, MA 02215

  • Phone+1 617-632-1070

  • Fax+1 617-632-1861

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Summary

  • Dr. Simon C. Robson is a Physician Scientist based in Boston, MA, with subspecialties in Hepatology, Transplantation, and in GI. He completed his medical education and training at the University of Cape Town/Groote Schuur Hospital and at Addenbrookes Hospital, Cambridge. He held post-doctoral fellowships at Kings College Hospital, London and Beth Israel Deaconess Medical Center in Boston after his Ph.D. was awarded. Dr. Robson holds several prominent positions, including Vice Chairman in Anesthesia at Beth Israel Lahey Health and Professor at Harvard Medical School. His expertise encompasses molecular mechanisms of inflammation. He has contributed extensively to basic research and discovery in the area of purinergic signaling, with numerous publications and involvement in clinical trials. Dr. Robson has received several honors, including plenary lectureships and teaching awards, highlighting his influence in the field.

Clinical Expertise

  • Hepatology, Viral hepatitides, Hepatic cirrhosis, Immunophenotyping, Hepatocellular cancer, Colon cancer, Infections and inflammation, MASLD

Education & Training

  • Beth Israel Deaconess Medical Center
    Beth Israel Deaconess Medical CenterPost-Doctoral Fellowship, 1993 - 1996
  • University of Cape Town
    University of Cape TownPhD, Immunology, 1985 - 1989
  • Kings College Hospital
    Kings College HospitalMRCP, 1982 - 1983
  • University of Cape Town Faculty of Medicine
    University of Cape Town Faculty of MedicineClass of 1978

Work Experience

  • Beth Israel Lahey Health
    Beth Israel Lahey HealthVice Chairman   ·   January 2018 - Current
  • HMS and BIDMC
    HMS and BIDMCProfessor   ·   July 2006 - Current
  • Harvard Medical School
    Harvard Medical SchoolProfessor   ·   January 1996 - Current
  • Harvard Medical School
    Harvard Medical SchoolVisiting Associate Professor   ·   January 1995 - Current
  • Beth Israel Deaconess Medical Center
    Beth Israel Deaconess Medical Center (Boston, MA)Project Leader And Pi   ·   January 1994 - Current
  • Harvard Medical School
    Harvard Medical SchoolProfessor   ·   January 1993 - Current
  • Beth Israel Deaconess Health System
    Beth Israel Deaconess Health SystemAttending Physician   ·  
  • University of Cape Town, Liver Center
    University of Cape Town, Liver CenterSenior Lecturer (Hon.)   ·   January 1997 - Current
  • Liver Clinic, Groote Schuur Hospital
    Liver Clinic, Groote Schuur HospitalMedical Staff   ·   January 1995 - January 1996
  • Center for Immunobiology, Harvard Medical School
    Center for Immunobiology, Harvard Medical SchoolAssociate Scientist   ·   January 1993 - January 1997
  • Groote Schuur Hospital
    Groote Schuur HospitalSenior Specialist   ·   January 1989 - January 1991
  • Schuur Hospital
    Schuur HospitalSenior Specialist   ·   January 1989 - January 1991
  • Saunders and Kirsch Firms
    Saunders and Kirsch FirmsSpecialist Physician   ·   January 1987 - January 1989
  • University of Cape Town and MRC, Liver Center
    University of Cape Town and MRC, Liver CenterSpecialist Scientist, Medical Research Council (Mrc)   ·   January 1987 - January 1989
  • Saunders and Kirsch Firms, Groote
    Saunders and Kirsch Firms, GrooteSpecialist Physician   ·   January 1987 - January 1989
  • University of Cape Town, Groote Schuur Hospital and Affiliated Teaching Hospitals
    University of Cape Town, Groote Schuur Hospital and Affiliated Teaching HospitalsParticipant And Organizer   ·   January 1987 - January 1993
  • University of Cape Town and Medical Research Council of South Africa Liver Center
    University of Cape Town and Medical Research Council of South Africa Liver CenterFull Time Consultant And Specialist Physician   ·   January 1987 - January 1993
  • Groote Schuur Hospital and Red Cross Children's Hospital
    Groote Schuur Hospital and Red Cross Children's HospitalSenior House Officer   ·   - January 1980
  • Warwick Hospital
    Warwick HospitalMedical Officer   ·   - January 1982

Certifications & Licensure

  • MA State Medical License
    MA State Medical License 1997 - 2026
  • Internal Medicine
    American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

  • Plenary and Keynote Lectures PURINES2018, PURINES2022, 2018, 2022
  • John Hedley-Whyte Lectureship Anesthesia, BIDMC, 2021
  • Subcommittee of Professors Harvard Medical School, 2018, 2020-2021
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Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Adenosine generation by CD39 and CD73 on T regulatory cells mediates immune suppression  
    Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, Chen JF, Enjyoji K, Linden J, Oukka M, Kuchroo VK, Strom TB, Robson SC, The Journal of Experimental Medicine, 1/1/2007
  • Purinergic Signaling during Inflammation  
    Eltzschig HK, Sitkovsky MV, Robson SC, N Engl J Med, 12/13/2012
  • Pulmonary natural killer T cells play an essential role in mediating hyperoxic acute lung injury  
    Nowak-Machen M, Schmelzle M, Hanidziar D, Junger W, Exley M, Otterbein L, Wu Y, Csizmadia E, Doherty G, Sitkovsky M, Robson SC, Am J Respir Cell Mol Biol, 5/1/2013
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Books/Book Chapters

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Abstracts/Posters

  • Adenosine A1 and A2A Receptors. CD39/CD73KO Influence Granulomatousresponses to BCG
    Kara FM, Montesinos MC, Mor A, Robson SC, Thompson L, Cronstein BN, 8th International Symposium on Adenosine and Adenine Nucleotides, Ferrara, Italy, 5/1/2006
  • Lower Risk of Cardiac Rupture in CD39 Null Mice Post-myocardial Infarction
    Ogawa M, Ogawa N, Nakayama M, Csizmadia E, Enjyoji K, Kohzuki M, Robson SC, J. American College of Cardiology, 1/1/2005
  • Transcription Factor YY1 and the Retinoblastoma Protein Are Downstream Targets of CD39/ENTPD1 Signaling Pathways during Liver Regeneration
    Wu Y, Imai M, Sun X, Csizmadia E, Enjyoji K, Choi C, Robson SC,Usheva A, Hepatology, 1/1/2005
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Lectures

  • Vascular Biology of CD39 and Transplantation Topics 
    Department of Gastroenterology, BIDMC - 1/1/2021
  • Vascular Bed-specific Characteristics of Endothelial Cells 
    Department of Gastroenterology, Mount Sinai Hospital, NY - 1/1/2013
  • Purinergic Signaling in the Liver 
    London, UK - 1/1/2013
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Other

  • Hepatic Xenotransplantation. Transplant Report 

    1/1/1995
  • Contributions to Reports in Cape Times, Hepatitis B Immunizations and Liver Transplantation 
    Robson
    1/1/1993
  • Audio-mix, and Pathways to Health 
    Radio Today
    1/1/1993
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Grant Support

  • T cell genotype/phenotype influence on atherosclerotic cardiovascular disease.NIH2023–2027
  • Targeting ENTPD3 to boost extracellular ATP and inflame tumors.Emerson Collective CRF2021–2023
  • PGC-1α, Purines and the Postmenopausal Heart.NIH NIA2021–2023
  • DAMP-Mediated Innate Immune Failure and Pneumonia .....DoD2016–2022
  • Directed Purinergic Signaling as Immunotherapy in LeukemiaNIH NCI2018–2020
  • Engineering Inhibitory Antibodies To Ectoenzymes For Cancer TreatmentNational Cancer Institute2012
  • Thromboregulatory Barriers To XenotransplantationNational Institute Of Allergy And Infectious Diseases2000–2011
  • Purinergic ThromboregulationNational Heart, Lung, And Blood Institute2009–2010
  • Thromboregulatory Strategies To Prolong Xenograft Survival.National Institute Of Allergy And Infectious Diseases2006–2009
  • Vascular Topography Of Cd39/NtpdasesNational Heart, Lung, And Blood Institute2004–2008
  • Core--Histological SupportNational Heart, Lung, And Blood Institute2004–2008
  • Functional Analysis Of Vascular NtpdasesNational Heart, Lung, And Blood Institute2000–2007
  • Thromboregulatory Strategies To Prolong XenograftsNational Institute Of Allergy And Infectious Diseases2005
  • Vascular Ntpdases And TransplantationNational Heart, Lung, And Blood Institute2001–2004
  • Vascular Ecto Adpases And TransplantationNational Heart, Lung, And Blood Institute1997–2000

Committees

  • Member, SOP HMS 2018 - 2021

Research History

  • Vice Chair Research AnesthesiaDirector of Center for Inflammation Research2019 - Present

Professional Memberships

Other Languages

  • Dutch

Industry Relationships

  • Scientific Founder, ePURINES2018 - Present
  • Scientific Founder, Purinomia2017 - Present

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