SolenGokhanMD

PubMed

• 21 citations
  Modeling CSF-1 receptor deficiency diseases - how close are we?
  Violeta Chitu, Solen Gokhan, E. Richard Stanley> ;The FEBS Journal. 2021 Jul 5
• 17 citations
  Microglial reduction of colony stimulating factor-1 receptor expression is sufficient to confer adult onset leukodystrophy.
  Fabrizio Biundo, Violeta Chitu, Gabriel G. L. Shlager, Eun S. Park, Maria Gulinello, Kusumika Saha, Harmony C. Ketchum, Christopher Fernandes, Solen Gokhan, Mark F. Me...> ;Glia. 2021 Mar 1
• 45 citations
  Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling.
  Violeta Chitu, Fabrizio Biundo, Gabriel G. L. Shlager, Eun S. Park, Ping Wang, Maria Gulinello, Solen Gokhan, Harmony C. Ketchum, Kusumika Saha, Michael DeTure, Dennis...> ;Cell Reports. 2020 Mar 3
• 28 citations
  Loss-of-Huntingtin in Medial and Lateral Ganglionic Lineages Differentially Disrupts Regional Interneuron and Projection Neuron Subtypes and Promotes Huntington's Dise...
  Mark F. Mehler, Jenna R. Petronglo, Eduardo E. Arteaga-Bracho, Maria Gulinello, Michael L. Winchester, Nandini Pichamoorthy, Stephen K. Young, Christopher D. DeJesus, ...> ;The Journal of Neuroscience. 2019 Mar 6
• 47 citations
  Postnatal and adult consequences of loss of huntingtin during development: Implications for Huntington's disease
  Eduardo E. Arteaga-Bracho, Maria Gulinello, Michael L. Winchester, Nandini Pichamoorthy, Jenna R. Petronglo, Alicia D. Zambrano, Julio F. Inocencio, Chirstopher D. De ...> ;Neurobiology of Disease. 2016 Dec 1
• 214 citations
  Emerging Roles for CSF-1 Receptor and its Ligands in the Nervous System
  Violeta Chitu, Solen Gokhan, Sayan Nandi, Mark F. Mehler, E. Richard Stanley> ;Trends in Neurosciences. 2016 Jun 1
• 86 citations
  Selective expression of mutant huntingtin during development recapitulates characteristic features of Huntington's disease.
  Aldrin E. Molero, Eduardo E. Arteaga-Bracho, Christopher H. Chen, Maria Gulinello, Michael L. Winchester, Nandini Pichamoorthy, Solen Gokhan, Kamran Khodakhah, Mark F....> ;Proceedings of the National Academy of Sciences of the United States of America. 2016 May 17
• 15 citations
  Hippocampal-dependent neurocognitive impairment following cranial irradiation observed in pre-clinical models: current knowledge and possible future directions.
  Wolfgang A. Tomé, Solen Gokhan, Maria Gulinello, N. Patrik Brodin, John Heard, Mark F. Mehler, Chandan Guha> ;The British Journal of Radiology. 2016 Jan 1
• 24 citations
  A mouse model replicating hippocampal sparing cranial irradiation in humans: A tool for identifying new strategies to limit neurocognitive decline
  Wolfgang A. Tomé, Solen Gokhan, N. Patrik Brodin, Maria Gulinello, John Heard, Mark F. Mehler, Chandan Guha> ;Scientific Reports. 2015 Sep 24
• 71 citations
  Phenotypic characterization of a Csf1r haploinsufficient mouse model of adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP)
  Violeta Chitu, Solen Gokhan, Maria Gulinello, Craig A. Branch, Madhuvati Patil, Ranu Basu, Corrina Stoddart, Mark F. Mehler, E. Richard Stanley> ;Neurobiology of Disease. 2015 Feb 1
• 6 citations
  The Role of H1 Linker Histone Subtypes in Preserving the Fidelity of Elaboration of Mesendodermal and Neuroectodermal Lineages during Embryonic Development
  Giang D. Nguyen, Solen Gokhan, Aldrin E. Molero, Seung Min Yang, Byung Ju Kim, Arthur I. Skoultchi, Mark F. Mehler> ;Plos One. 2014 May 6
• 19 citations
  Functions of huntingtin in germ layer specification and organogenesis.
  Giang D. Nguyen, Aldrin E. Molero, Solen Gokhan, Mark F. Mehler> ;Plos One. 2013 Aug 13
• 111 citations
  Receptor-type Protein-tyrosine Phosphatase ζ Is a Functional Receptor for Interleukin-34
  Sayan Nandi, Mario Cioce, Yee Guide Yeung, Edward Nieves, Lydia Tesfa, Haishan Lin, Amy W. Hsu, Robert Halenbeck, Hui Yong Cheng, Solen Gokhan, Mark F. Mehler, E. Rich...> ;The Journal of Biological Chemistry. 2013 Jul 26
• 36 citations
  Selective Roles of Normal and Mutant Huntingtin in Neural Induction and Early Neurogenesis
  Giang D. Nguyen, Solen Gokhan, Aldrin E. Molero, Mark F. Mehler> ;Plos One. 2013 May 14
• 231 citations
  The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation
  Sayan Nandi, Solen Gokhan, Xuming Dai, Suwen Wei, Grigori Enikolopov, Haishan Lin, Mark F. Mehler, E. Richard Stanley> ;Developmental Biology. 2012 Jul 15
• 108 citations
  REST and CoREST are transcriptional and epigenetic regulators of seminal neural fate decisions.
  Irfan A. Qureshi, Solen Gokhan, Mark F. Mehler> ;Cell Cycle. 2010 Nov 15
• 3304 citations
  Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
  Florent Ginhoux, Melanie Greter, Marylene Leboeuf, Sayan Nandi, Peter See, Solen Gokhan, Mark F. Mehler, Simon J. Conway, Lai Guan Ng, E. Richard Stanley, Igor M. Samo...> ;Science. 2010 Nov 5
• 45 citations
  Corepressor for element-1–silencing transcription factor preferentially mediates gene networks underlying neural stem cell fate decisions
  Joseph J. Abrajano, Irfan A. Qureshi, Solen Gokhan, Aldrin E. Molero, Deyou Zheng, Aviv Bergman, Mark F. Mehler> ;Proceedings of the National Academy of Sciences of the United States of America. 2010 Sep 21
• 327 citations
  Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation
  Tim R. Mercer, Irfan A. Qureshi, Solen Gokhan, Marcel E. Dinger, Guangyu Li, John S. Mattick, Mark F. Mehler> ;BMC Neuroscience. 2010 Feb 5
• 85 citations
  Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease
  Aldrin E. Molero, Solen Gokhan, Sara Gonzalez, Jessica L. Feig, Lucien C. Alexandre, Mark F. Mehler> ;Proceedings of the National Academy of Sciences of the United States of America. 2009 Dec 22
• 100 citations
  REST and CoREST Modulate Neuronal Subtype Specification, Maturation and Maintenance
  Joseph J. Abrajano, Irfan A. Qureshi, Solen Gokhan, Deyou Zheng, Aviv Bergman, Mark F. Mehler> ;Plos One. 2009 Dec 7
• 76 citations
  Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation.
  Joseph J. Abrajano, Irfan A. Qureshi, Solen Gokhan, Deyou Zheng, Aviv Bergman, Mark F. Mehler> ;Plos One. 2009 Nov 3
• 101 citations
  Combinatorial Profiles of Oligodendrocyte-Selective Classes of Transcriptional Regulators Differentially Modulate Myelin Basic Protein Gene Expression
  Solen Gokhan, Mireya Marin-Husstege, Shau Yu Yung, Darah Fontanez, Patrizia Casaccia-Bonnefil, Mark F. Mehler> ;The Journal of Neuroscience. 2005 Sep 7
• 27 citations
  De novo neurogenesis and acute stroke: are exogenous stem cells really necessary?
  John M. Abrahams, Solen Gokhan, Eugene S. Flamm, Mark F. Mehler> ;Neurosurgery. 2004 Jan 1
• 110 citations
  Differential modulation of BMP signaling promotes the elaboration of cerebral cortical GABAergic neurons or oligodendrocytes from a common sonic hedgehog-responsive ve...
  Shau Yu Yung, Solen Gokhan, Jennifer Jurcsak, Aldrin E. Molero, Joseph J. Abrajano, Mark F. Mehler> ;Proceedings of the National Academy of Sciences of the United States of America. 2002 Dec 10
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Journal Articles

• Hippocampal-dependent Neurocognitive Impairment Following Cranial Irradiation Observed in Preclinical Models: Current Knowledge and Possible Future Directions.  
  Tomé WA, Gökhan Ş, Gulinello ME, Brodin NP, Heard J, Mehler MF, Guha C., Br J Radiol