TiffanyOsbornMDMPH

Emergency Medicine • Saint Louis, MO

Critical Care Medicine

Associate Professor, Surgery, Washington University in St. Louis School of Medicine

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Office
1 Barnes Jewish Hospital Plz
Saint Louis, MO 63110
Phone+1 314-362-1272
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Education & Training

London School of Hygiene and Tropical MedicineMPH, Public Health, 2007 - 2009
University of MarylandFellowship, Surgical Critical Care, 2000 - 2002
University of MarylandResidency, Emergency Medicine, 1997 - 2000
The University of Texas Health Science Center at San AntonioClass of 1997

Certifications & Licensure

IL State Medical License 2021 - 2026
MO State Medical License 2011 - 2025
VA State Medical License 2002 - 2018
MD State Medical License 2001 - 2003
American Board of Emergency Medicine Emergency Medicine
American Board of Emergency Medicine Internal Medicine-Critical Care Medicine
European Intensive Care Board CertificationCritical Care

Awards, Honors, & Recognition

Fellowship American College of Emergency Physicians, 2010

Clinical Trials

Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Washington University Start of enrollment: 2020 Feb 03
Completed

Publications & Presentations

PubMed

8 citations
Surviving Sepsis Campaign.
R Phillip Dellinger, Andrew Rhodes, Laura Evans, Waleed Alhazzani, Richard Beale, Roman Jaeschke, Flavia R Machado, Henry Masur, Tiffany Osborn, Margaret M Parker, Chr...> ;Critical Care Medicine. 2023 Apr 1
1 citations
The authors reply.
Thomas P Bleck, Timothy G Buchman, Cherylee W J Chang, R Phillip Dellinger, Clifford S Deutschman, Sameer S Kadri, John C Marshall, David M Maslove, Henry Masur, Tiffa...> ;Critical Care Medicine. 2022 Jun 1
140 citations
Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021.
Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M. Coopersmith, Craig French, Flávia Ribeiro Machado, Lauralyn McIntyre, Marlies Ostermann, Hall...> ;Critical Care Medicine. 2021 Nov 1
367 citations
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M. Coopersmith, Craig French, Flávia Ribeiro Machado, Lauralyn McIntyre, Marlies Ostermann, Hall...> ;Critical Care Medicine. 2021 Nov 1
1519 citations
Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.
Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M. Coopersmith, Craig French, Flávia Ribeiro Machado, Lauralyn McIntyre, Marlies Ostermann, Hall...> ;Intensive Care Medicine. 2021 Oct 2
26 citations
A Multi-mRNA Host-Response Molecular Blood Test for the Diagnosis and Prognosis of Acute Infections and Sepsis: Proceedings from a Clinical Advisory Panel.
James Ducharme, Wesley H. Self, Tiffany M. Osborn, Nathan A. Ledeboer, Jonathan Romanowsky, Timothy E. Sweeney, Oliver Liesenfeld, Richard E. Rothman> ;Journal of Personalized Medicine. 2020 Dec 7
1 citations
The Importance of Universal Preprocedural Testing for the Novel Coronavirus 2019
Felicia Zhang, William C. Chapman, Grant V. Bochicchio, Obeid N. Ilahi, Tiffany M. Osborn> ;Critical Care Explorations. 2020 May 22
46 citations
Monocyte distribution width enhances early sepsis detection in the emergency department beyond SIRS and qSOFA.
Elliott D. Crouser, Joseph E. Parrillo, Greg S. Martin, David T. Huang, Pierre Hausfater, Ilya L. Grigorov, Diana B. Careaga, Tiffany M. Osborn, Hasan Mohamad, Liliana...> ;Journal of Intensive Care. 2020 May 5
10 citations
Who Owns Sepsis
Michael Klompas, Tiffany M. Osborn, Chanu Rhee> ;Annals of Internal Medicine. 2020 Jan 28
1 citations
Sepsis Mandates Help Clinicians and Patients.
Tiffany M. Osborn> ;Critical Care Medicine. 2020 Jun 1
10 citations
Comparison of Automated Sepsis Identification Methods and Electronic Health Record-based Sepsis Phenotyping: Improving Case Identification Accuracy by Accounting for C...
Katharine Henry, David N. Hager, Tiffany M. Osborn, Albert W. Wu, Suchi Saria> ;Critical Care Explorations. 2019 Oct 30
9 citations
Urban and Rural Emergency Department Performance on National Quality Metrics for Sepsis Care in the United States
Margaret B. Greenwood-Ericksen, Craig Rothenberg, Nicholas M. Mohr, Shawn D. Andrea, Todd Slesinger, Tiffany M. Osborn, Jessica S. Whittle, Pawan Goyal, Nalani Tarrant...> ;The Journal of Rural Health. 2019 Sep 1
87 citations
Mortality Changes Associated with Mandated Public Reporting for Sepsis. The Results of the New York State Initiative
Mitchell M. Levy, Foster C. Gesten, Gary Phillips, Kathleen M. Terry, Christopher W. Seymour, Hallie C. Prescott, Marcus Friedrich, Theodore J. Iwashyna, Tiffany M. Os...> ;American Journal of Respiratory and Critical Care Medicine. 2018 Dec 1
56 citations
A global perspective on vasoactive agents in shock
Djillali Annane, Lamia Ouanes-Besbes, Daniel De Backer, Bin Du, Anthony C. Gordon, Glenn Hernandez, Keith M. Olsen, Tiffany M. Osborn, Sandra L. Peake, James A. Russel...> ;Intensive Care Medicine. 2018 Jun 4
31 citations
Reporting of Sepsis Cases for Performance Measurement Versus for Reimbursement in New York State.
Hallie C. Prescott, Tara Cope, Foster C. Gesten, Tatiana Ledneva, Marcus Friedrich, Theodore J. Iwashyna, Tiffany M. Osborn, Christopher W. Seymour, Mitchell M. Levy> ;Critical Care Medicine. 2018 May 1
5 citations
Sepsis in the older person: The ravages of time and bacteria.
Ellen Burkett, Stephen P J Macdonald, Chris Carpenter, Glenn Arendts, Carolyn Hullick, Guruprasad Nagaraj, Tiffany M. Osborn> ;Emergency Medicine Australasia. 2018 Apr 1
19 citations
The New York Sepsis Severity Score: Development of a Risk-Adjusted Severity Model for Sepsis.
Gary Phillips, Tiffany M. Osborn, Kathleen M. Terry, Foster C. Gesten, Mitchell M. Levy, Stanley Lemeshow> ;Critical Care Medicine. 2017 Dec 1
45 citations
Preliminary Performance on the New CMS Sepsis-1 National Quality Measure: Early Insights From the Emergency Quality Network (E-QUAL).
Arjun K. Venkatesh, Todd Slesinger, Jessica S. Whittle, Tiffany M. Osborn, Emily L. Aaronson, Craig Rothenberg, Nalani Tarrant, Pawan Goyal, Donald M. Yealy, Jeremiah ...> ;Annals of Emergency Medicine. 2018 Jan 1
1115 citations
Time to treatment and mortality during mandated emergency care for sepsis
Christopher W. Seymour, Foster C. Gesten, Hallie C. Prescott, Marcus Friedrich, Theodore J. Iwashyna, Gary Phillips, Stanley Lemeshow, Tiffany M. Osborn, Kathleen M. T...> ;The New England Journal of Medicine. 2017 May 21
40 citations
Severe Sepsis and Septic Shock Trials (ProCESS, ARISE, ProMISe): What is Optimal Resuscitation?
Tiffany M. Osborn> ;Critical Care Clinics. 2017 Apr 1
4870 citations
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
Andrew Rhodes, Laura Evans, Waleed Alhazzani, Mitchell M. Levy, Massimo Antonelli, Ricard Ferrer, Anand Kumar, Jonathan E. Sevransky, Charles L. Sprung, Mark E. Nunnal...> ;Critical Care Medicine. 2017 Mar 1
6327 citations
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016
Andrew Rhodes, Laura Evans, Waleed Alhazzani, Mitchell M. Levy, Massimo Antonelli, Ricard Ferrer, Anand Kumar, Jonathan E. Sevransky, Charles L. Sprung, Mark E. Nunnal...> ;Intensive Care Medicine. 2017 Jan 18
50 citations
Application of a Framework to Assess the Usefulness of Alternative Sepsis Criteria.
Christopher W. Seymour, Craig M. Coopersmith, Clifford S. Deutschman, Foster C. Gesten, Michael Klompas, Mitchell M. Levy, Gregory S. Martin, Tiffany M. Osborn, Chanu ...> ;Critical Care Medicine. 2016 Mar 1
98 citations
A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria.
Derek C. Angus, Christopher W. Seymour, Craig M. Coopersmith, Clifford S. Deutschman, Michael Klompas, Mitchell M. Levy, Gregory S. Martin, Tiffany M. Osborn, Chanu Rh...> ;Critical Care Medicine. 2016 Mar 1
64 citations
Protocolised Management In Sepsis (ProMISe): a multicentre randomised controlled trial of the clinical effectiveness and cost-effectiveness of early, goal-directed, pr...
Paul R Mouncey, Tiffany M. Osborn, G. Sarah Power, David A Harrison, M Zia Sadique, Richard Grieve, Rahi Jahan, Jermaine C K Tan, Sheila Harvey, Derek Bell, Julian Bio...> ;Health Technology Assessment. 2015 Nov 1
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Journal Articles

Trial of Early, Goal-Directed Resuscitation for Septic Shock
Mouncey PR, Osborn TM, Power S, Harrison DA, Sadique Z, Grieve RD, Jahan R, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM, NEJM, 3/17/2015

Press Mentions

The Omicron Surge: How Hospitals Are CopingJanuary 3rd, 2022
ICU Teams Report Fatigue and Frustration as They Brace for Omicron SurgeDecember 31st, 2021
Gasping for Air: Watching the Insurrection from the COVID-19 ICUMay 5th, 2021
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