ToddJJanusMD

Neurology • Des Moines, IA

Neuroimmunology/Multiple Sclerosis

Physician

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Office
555 south johnson
Des Moines, IA 50312
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Education & Training

University of Texas M.D. Anderson Cancer Center1990 - 1992
University of Texas Health Science Center at HoustonResidency, Neurology, 1987 - 1990
University of Texas Health Science Center at HoustonInternship, Internal Medicine, 1986 - 1987
Rush Medical College of Rush University Medical CenterClass of 1986, MD, Samuel Taylor Award in Medical Oncology
Northwestern UniversityPhD, Biochemistry , 1977 - 1984
Drake UniversityBA, Chemistry, 1973 - 1977

Certifications & Licensure

IA State Medical License 1991 - 2025
IN State Medical License 2001 - 2025
IL State Medical License 1998 - 2005
TX State Medical License 1987 - 1992
American Board of Psychiatry and Neurology Neurology
National Board of Physicians and Surgeons Neurology
American Society for Clinical PathologyHT

Awards, Honors, & Recognition

Man of the Year - 2006 Time Magazine
Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2012
Palatucci Advocacy Leadership Forum American Acad. of Neurology
Eagle Scout Boy Scouts of America
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Clinical Trials

Study of Fampridine-ER Tablets in Patients With Multiple Sclerosis Start of enrollment: 2011 Mar 01
Completed
Phase 3

Publications & Presentations

PubMed

Reader response: Right Brain: Withholding treatment from a child with an epileptic encephalomyopathy
Todd J. Janus> ;Neurology. 2019 Jan 1
Special considerations when coding for patients with multiple sclerosis.
Todd J. Janus> ;Continuum. 2013 Aug 1
10 citations
Clinical indicators of midface fracture in patients with trauma.
Hayden L. Smith, Elizabeth A. Chrischilles, Todd J. Janus, Richard A. Sidwell, Marizen R. Ramirez, Corinne Peek-Asa, Sheryl M Sahr> ;Dental Traumatology. 2013 Aug 1
7 citations
Hospital discharge destinations for Hispanic and non-Hispanic white patients treated for traumatic brain injury.
Todd J. Janus, Hayden L. Smith, Angela Chigazola, Mikelle R. Wortman, Richard A. Sidwell, John G. Piper> ;Journal of Trauma Nursing. 2013 Apr 1
Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial.
Coles AJ Twyman CL Arnold DL Cohen JA Confavreux C Fox EJ Hartung HP Havrdova E Selmaj KW Weiner HL Miller T Fisher E Sandbrink R Lake SL Margolin DH Oyuela P Panzara ...> ;Lancet. 2012 Nov 24
Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis.
Gold R Kappos L Arnold DL Bar-Or A Giovannoni G Selmaj K Tornatore C Sweetser MT Yang M Sheikh SI Dawson KT> ;N Engl J Med. 2012 Sep 20
2 citations
Predictors of pneumonia in trauma patients with pulmonary contusion.
Todd J. Janus, Mary Vaughan-Sarrazin, Larry J. Baker, Hayden L. Smith> ;Journal of Trauma Nursing. 2012 Jul 1
1 citations
Same-day discharge after percutaneous coronary intervention.
Todd J. Janus> ;JAMA. 2012 Jan 18
33 citations
The Burden of Unhelmeted and Uninsured ATV Drivers and Passengers
Tricia L. Merrigan, Piper L Wall, Hayden L. Smith, Todd J. Janus, Richard A. Sidwell> ;Traffic Injury Prevention. 2011 Jun 8
37 citations
Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: an endothelin receptor antagonist for refractory prostate cancer.
Bernard A. Zonnenberg, Gerard Groenewegen, Todd J. Janus, Terri W. Leahy, Rod A. Humerickhouse, Jeffrey D. Isaacson, Robert A. Carr, Emile E. Voest> ;Clinical Cancer Research. 2003 Aug 1
123 citations
Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in Prostate cancer and reduces expression of osteoprotegerin in osteobl...
K. Fizazi, Jun Yang, Sara Peleg, Charles R. Sikes, Erica L. Kreimann, Danai D. Daliani, Matilde Olive, Kevin Raymond, Todd J. Janus, Christopher J. Logothetis, Gerard ...> ;Clinical Cancer Research. 2003 Jul 1
154 citations
A randomized, double-blind, placebo-controlled, phase 2 study of RMP-7 in combination with carboplatin administered intravenously for the treatment of recurrent malign...
Michael D. Prados, S. Clifford Schold, Howard A. Fine, Kurt A. Jaeckle, Fred H. Hochberg, Laszlo Mechtler, Michael R. Fetell, Surasak Phuphanich, Lynn G. Feun, Todd J....> ;Neuro-Oncology. 2003 Apr 1
126 citations
Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: Safety and pharmacokinetics
Michael A. Carducci, Joel B. Nelson, M. Kathy Bowling, Theresa Rogers, Mario A. Eisenberger, Victoria J. Sinibaldi, Ross C. Donehower, Terri L. Leahy, Robert A. Carr, ...> ;Journal of Clinical Oncology. 2002 Apr 15
35 citations
Phenotypic variability in monozygotic twins with neurofibromatosis 2.
Michael E. Baser, Nicola K. Ragge, Vincent M. Riccardi, Todd Janus, Bruce J. Gantz, Stefan M. Pulst> ;American Journal of Medical Genetics. 1996 Sep 6
46 citations
Neurologic and Neurobehavioral Effects of Electric and Lightning Injuries
Todd J. Janus, Joseph Barrash> ;The Journal of Burn Care & Rehabilitation. 1996 Sep 1
26 citations
Neurobehavioral sequelae of high voltage electrical injuries: comparison with traumatic brain injury.
Joseph Barrash, Gerald P. Kealey, Todd J. Janus> ;Applied Neuropsychology. 1996 May 1
73 citations
Use of [18F]fluorodeoxyglucose positron emission tomography in patients with primary malignant brain tumors
Todd J. Janus, E. Edmund Kim, Roy S. Tilbury, Janet M. Bruner, W. K. Alfred Yung> ;Annals of Neurology. 1993 May 1
24 citations
Adjuvant chemotherapy with carmustine and cisplatin for patients with malignant gliomas.
W. K. Alfred Yung, Todd J. Janus, Moshe H. Maor, Lynn G. Feun> ;Journal of Neuro-Oncology. 1992 Feb 1
Alpha-thrombin-catalyzed activation of human platelet factor XIII: relationship between proteolysis and factor XIIIa activity.
Hornyak TJ Bishop PD Shafer JA> ;Biochemistry. 1989 Sep 5
5 citations
Effect of Fibrinogen and Ca2+ on the Thrombin‐Catalyzed Proteolytic Event That Triggers Activation of Factor XIII
Jules A. Shafer, Sidney D. Lewis, Todd J. Janus, Laszlo Lorand> ;Annals of the New York Academy of Sciences. 1986 Dec 1
2 citations
Modulation of lymphocyte responsiveness to phytohemagglutinin by micromolecular fibrinogen degradation products
Todd J. Janus, Donald P. Braun, Jules E. Harris> ;Clinical Immunology and Immunopathology. 1986 Oct 1
72 citations
Regulation of formation of factor XIIIa by its fibrin substrates.
Sidney D. Lewis, Todd J. Janus, Laszlo Lorand, Jules A. Shafer> ;Biochemistry. 1985 Nov 19
71 citations
Promotion of thrombin-catalyzed activation of factor XIII by fibrinogen
Todd J. Janus, Sidney D. Lewis, Laszlo Lorand, Jules A. Shafer> ;Biochemistry. 1983 Dec 20
6 citations
Regulation of factor XIIIa generation by fibrinogen.
C. Gerald Curtis, Todd J. Janus, R. Bruce Credo, Laszlo Lorand> ;Annals of the New York Academy of Sciences. 1983 Jun 1
Factor XIII (fibrin-stabilizing factor).
Lorand L Credo RB Janus TJ> ;Methods Enzymol. 1981
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Books/Book Chapters

Principles and Practice of Behavioral Neurology & Neuropsychology
Chapter: Neurology and Neuropsychology In Oncology
Wefel, J.S. and Janus, T.JEditors: Rizzo M. & Eslinger P,.Saunders, Churchill Livingstone, & MosbyEdition 1,2005
Textbook of Clinical Neurology
Chapter: “Primary Neoplasms of the Brain”
Page 1017 - 1014Janus, T.J. and Yung, W.K.AEditors: Goetz C..W.B. Saunders, CoEdition 2,2003

Other

PATENT USA Nr. 7208517 Methods of Treating Cancer and the Pain Associated therewith using endothelin antagonists Case Nr. 6715.US.01, Serial Nr. 09/633,389 Filed 7 Aug...
Janus, TJ et al.
Washington, DC - 4/24/2007