ZhongYingMDPhD

PubMed

• Characteristics and Attendance of Patients Eligible for the PASS Clinic: A Transition of Care Model After Acute Symptomatic Seizures.
  Thompson, N., , Byrnes, M., Hantus, S., Fesler, J., Ying, Z., Ayub, N., Rubinos, C., Zafar, S., Sivaraju, A., Punia, V.> ;Neurology. Clinical Practice. 2024 Feb 1
• 18 citations
  A comprehensive clinico-pathological and genetic evaluation of bottom-of-sulcus focal cortical dysplasia in patients with difficult-to-localize focal epilepsy
  Zhong Ying, Irene Wang, Ingmar Blümcke, Juan Bulacio, Andreas V. Alexopoulos, Lara Jehi, William Bingaman, Jorge Gonzalez-Martinez, Katja Kobow, Lisa Marie Niestroj, D...> ;Epileptic Disorders. 2019 Feb 1
• 11 citations
  Preliminary report: Late seizure recurrence years after epilepsy surgery may be associated with alterations in brain tissue transcriptome.
  Lara Jehi, Lamis Yehia, Charissa Peterson, Farshad Niazi, Robyn M. Busch, Richard A. Prayson, Zhong Ying, William Bingaman, Imad Najm, Charis Eng> ;Epilepsia Open. 2018 May 17
• 184 citations
  Somatic Mutations Activating the mTOR Pathway in Dorsal Telencephalic Progenitors Cause a Continuum of Cortical Dysplasias
  Alissa M. D'Gama, Mollie B. Woodworth, Amer A. Hossain, Sara Bizzotto, Nicole E. Hatem, Christopher M. LaCoursiere, Imad Najm, Zhong Ying, Edward Yang, A. James Barkov...> ;Cell Reports. 2017 Dec 26
• 25 citations
  Growth Associated Protein 43 (GAP-43) as a Novel Target for the Diagnosis, Treatment and Prevention of Epileptogenesis
  Ashley D. Nemes, Katayoun Ayasoufi, Zhong Ying, Qi-Gang Zhou, Hoonkyo Suh, Imad Najm> ;Scientific Reports. 2017 Dec 18
• 2 citations
  Treatment with lacosamide impedes generalized seizures in a rodent model of cortical dysplasia.
  Ashley D. Nemes, Rebecca O’Dwyer, Imad Najm, Zhong Ying, Jorge Gonzalez-Martinez, Andreas V. Alexopoulos> ;Epilepsia. 2017 Aug 20
• 8 citations
  Underlying Cortical Dysplasia as Risk Factor for Traumatic Epilepsy: An Animal Study.
  Ashley D. Nemes, Imad Najm, John T. Gale, Zhong Ying, Matthew D. Johnson, Jorge Gonzalez-Martinez> ;Journal of Neurotrauma. 2016 Oct 15
• 12 citations
  Growth-associated protein 43 and progressive epilepsy in cortical dysplasia.
  Zhong Ying, Imad Najm, Ashley D. Nemes, Ana Paula Pinheiro-Martins, Andreas V. Alexopoulos, Jorge Gonzalez-Martinez, William Bingaman> ;Annals of Clinical and Translational Neurology. 2014 Jul 1
• 15 citations
  Glutamate clearance mechanisms in resected cortical dysplasia.
  Jorge Gonzalez-Martinez, Zhong Ying, Richard A. Prayson, William Bingaman, Imad Najm> ;Journal of Neurosurgery. 2011 Apr 1
• 12 citations
  Neuronal nitric oxide synthase expression in resected epileptic dysplastic neocortex
  Jorge Gonzalez-Martinez, Gabriel Möddel, Zhong Ying, Richard A. Prayson, William Bingaman, Imad Najm> ;Journal of Neurosurgery. 2009 Sep 16
• 22 citations
  Dissociation between in vitro and in vivo epileptogenicity in a rat model of cortical dysplasia
  Christoph Kellinghaus, Gabriel Möddel, Hiroshi Shigeto, Zhong Ying, Berit Jacobsson, Jorge Gonzalez-Martinez, Candice Burrier, Damir Janigro, Imad Najm> ;Epileptic Disorders. 2007 Feb 16
• 54 citations
  Expression of neural stem cell surface marker CD133 in balloon cells of human focal cortical dysplasia.
  Zhong Ying, Jorge Gonzalez-Martinez, Cristiane Q. Tilelli, William Bingaman, Imad Najm> ;Epilepsia. 2005 Nov 1
• 70 citations
  The NMDA receptor NR2B subunit contributes to epileptogenesis in human cortical dysplasia.
  Gabriel Möddel, Berit Jacobson, Zhong Ying, Damir Janigro, William Bingaman, Jorge Gonzalez-Martinez, Christoph Kellinghaus, Richard A. Prayson, Imad Najm> ;Brain Research. 2005 Jun 7
• 52 citations
  Severity of Histopathologic Abnormalities and In Vivo Epileptogenicity in the In Utero Radiation Model of Rats Is Dose Dependent
  Christoph Kellinghaus, Takeharu Kunieda, Zhong Ying, Andrew Pan, Hans Lüders, Imad Najm> ;Epilepsia. 2004 Jun 1
• 24 citations
  Temporal lobe volumes in patients with hippocampal sclerosis with or without cortical dysplasia
  Beate Diehl, Imad Najm, Eric LaPresto, Richard A. Prayson, Paul Ruggieri, Armin Mohamed, Zhong Ying, Michael L. Lieber, Thomas L. Babb, W. Bingaman, Hans Lüders> ;Neurology. 2004 May 25
• 57 citations
  Increased Numbers of Coassembled PSD-95 to NMDA-receptor Subunits NR2B and NR1 in Human Epileptic Cortical Dysplasia
  Zhong Ying, William Bingaman, Imad Najm> ;Epilepsia. 2004 Apr 1
• 47 citations
  Mechanisms of epileptogenicity in cortical dysplasias.
  Imad Najm, Zhong Ying, Thomas L. Babb, Peter B. Crino, Robert L. Macdonald, Gary W. Mathern, Roberto Spreafico> ;Neurology. 2004 Mar 23
• 23 citations
  Gene expression profile of neurodegeneration induced by α1B‐adrenergic receptor overactivity: NMDA/GABAA dysregulation and apoptosis
  June Yun, Robert J. Gaivin, Dan F. McCune, Attaporn Boongird, Robert S. Papay, Zhong Ying, Pedro J. Gonzalez-Cabrera, Imad Najm, Dianne M. Perez> ;Brain. 2003 Dec 1
• 41 citations
  Neocortical Temporal FDG‐PET Hypometabolism Correlates with Temporal Lobe Atrophy in Hippocampal Sclerosis Associated with Microscopic Cortical Dysplasia
  Beate Diehl, Eric LaPresto, Imad Najm, Shanker Raja, Sabine Rona, Thomas L. Babb, Zhong Ying, William Bingaman, Hans Lüders, Paul Ruggieri> ;Epilepsia. 2003 Apr 1
• 139 citations
  Epileptogenicity of Focal Malformations Due to Abnormal Cortical Development: Direct Electrocorticographic–Histopathologic Correlations
  Kanokwan Boonyapisit, Imad Najm, George Klem, Zhong Ying, Candice Burrier, Eric LaPresto, Dileep Nair, William Bingaman, Richard A. Prayson, Hans Lüders> ;Epilepsia. 2003 Jan 1
• 13 citations
  Interictal EEG, hippocampal atrophy, and cell densities in hippocampal sclerosis and hippocampal sclerosis associated with microscopic cortical dysplasia.
  Beate Diehl, Imad Najm, Armin Mohamed, Thomas L. Babb, Zhong Ying, William Bingaman> ;Journal of Clinical Neurophysiology. 2002 Apr 1
• 8 citations
  Mechanisms of epileptogenicity in focal malformations caused by abnormal cortical development
  Zhong Ying, Imad Najm> ;Neurosurgery Clinics of North America. 2002 Jan 1
• 126 citations
  Focal cortical dysplasias in eloquent cortex : functional characteristics and correlation with MRI and histopathologic changes
  Petr Marusic, Imad Najm, Zhong Ying, Richard A. Prayson, Sabine Rona, Dileep Nair, Eldad Hadar, Prakash Kotagal, Mark D. Bej, Elaine Wyllie, William Bingaman, Hans Lüders> ;Epilepsia. 2002 Jan 1
• 12 citations
  Fluid-attenuated inversion recovery: Correlations of hippocampal cell densities with signal abnormalities
  Beate Diehl, Imad Najm, Armin Mohamed, Elaine Wyllie, Thomas L. Babb, Zhong Ying, A. Hilbig, William Bingaman, Hans Lüders, Paul Ruggieri> ;Neurology. 2001 Sep 25
• 136 citations
  Temporal lobe epilepsy due to hippocampal sclerosis in pediatric candidates for epilepsy surgery
  Armin Mohamed, Elaine Wyllie, Paul Ruggieri, Prakash Kotagal, Thomas L. Babb, A. Hilbig, Christi Wylie, Zhong Ying, S. Staugaitis, Imad Najm, Juan Bulacio, Nancy Foldv...> ;Neurology. 2001 Jun 26
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Journal Articles

• Growth-associated protein 43 and progressive epilepsy in cortical  
  Ying Z, Najm I, Nemes A, Pinheiro-Martins A, Alexopoulos A, Gonzalez-Martinez J. Bingaman W, Annals of Clinical and Translational Neurology, 1/1/2014
• clearance mechanisms in cortical  
  Gonzalez-Martinez JA, Ying Z, Prayson R, Bingaman W, Najm I, J Neurosurg, 1/1/2011
• Neuronal oxide expression in epileptic  
  Gonzalez-Martinez JA, Möddel G, Ying Z, Prayson RA, Bingaman WE, Najm IM, J Neurosurg, 1/1/2009
• Dissociation between in vitro and in vivo in a rat model of cortical  
  Kellinghaus C, Moddel G, Shigetol H, Ying Z, Jacobson B, Gonzalez-martinez, J, Burrier C, Janigro D, Najm IM, Epileptic Disorder, 1/1/2007
• The NMDA receptor NR2B subunit contributes to in human cortical  
  Moddel G, Jacobson B, Ying Z, Janigro D, Bingaman W, Gonzalez-Martinez , Kellinghaus C, Prayson RA, Najm IM, Brain Res, 1/7/2005
• Expression of neural stem cell surface marker CD133 in balloon cells of human focal cortical  
  Ying Z, Gonzalez-Martinez J, Tilelli C, Bingaman W, Najm I, Epilepsia, 1/1/2005
• Temporal lobe volumes in patients with sclerosis with or without cortical  
  Diehl B, Najm I, LaPresto E, Prayson R, Ruggieri P, Mohamed A, Ying Z, Lieber M, Babb T, Bingaman W, Luders HO, Neurology, 1/25/2004
• Severity of abnormalities and in vivo in the in radiation model of rats is dose dependent  
  Kellinghaus C, Kunieda T, Ying Z, Pan A, Luders HO, Najm IM, Epilepsia, 1/24/2004
• Mechanisms of in cortical  
  Najm I, Ying Z, Babb T, Crino PB, Macdonald R, Mathern GW, Spreafico R, Neurology, 1/23/2004
• Increased numbers of PSD-95 to NMDA-receptor subunits NR2B and NR1 in human epileptic cortical  
  Ying Z, Bingaman W, Najm IM, Epilepsia, 1/1/2004
• Gene expression profile of induced by alpha1B-adrenergic receptor : NMDA/GABAA and  
  Yun J, Gaivin RJ, McCune DF, Boongird A, Papay RS, Ying Z, Gonzalez-Cabrera PJ, Najm I, Perez DM, Brain, 1/1/2003
• temporal FDG-PET correlates with temporal lobe atrophy in sclerosis associated with microscopic cortical  
  Diehl B, LaPresto E, Najm I, Raja S, Rona S, Babb T, Ying Z, Bingaman W, Luders HO, Ruggieri P, Epilepsia, 1/1/2003
• of focal malformations due to abnormal cortical development: direct - correlations  
  Boonyapisit K, Najm I, Klem G, Ying Z, Burrier C, LaPresto E, Nair D, Bingaman W, Prayson R, Luders H, Epilepsia, 1/1/2003
• EEG, atrophy, and cell densities in sclerosis and sclerosis associated with microscopic cortical  
  Diehl B, Najm I, Mohamed A, Babb T, Ying Z, Bingaman W, Clin Neurophysiol, 1/1/2002
• Focal cortical in eloquent cortex: functional characteristics and correlation with MRI and changes  
  Marusic P, Najm IM, Ying Z, Prayson R, Rona S, Nair D, Hadar E, Kotagal P, Bej MD, Wyllie E, Bingaman W, Luders H, Epilepsia, 1/1/2002
• Mechanisms of in focal malformations caused by abnormal cortical development  
  Ying Z, Najm IM, Neurosurg Clin N Am, 1/1/2002
• Temporal lobe epilepsy due to sclerosis in pediatric candidates for epilepsy surgery  
  Mohamed A, Wyllie E, Ruggieri P, Kotagal P, Babb T, Hilbig A, Wylie C, Ying Z, Staugaitis S, Najm I, Bulacio J, Foldvary N, Luders H, Bingaman W, Neurology, 1/26/2001
• Fluid-attenuated inversion recovery: correlations of cell densities with signal abnormalities  
  Diehl B, Najm I, Mohamed A, Wyllie E, Babb T, Ying Z, Hilbig A, Bingaman W, Luders HO, Ruggieri P, Neurology, 1/25/2001
• Mechanisms of  
  Najm I, Ying Z, Janigro D, Neurol Clin, 1/1/2001
• Brain plasticity and cellular mechanisms of in human and experimental cortical  
  Babb TL, Ying Z, Mikuni N, Nishiyama K, Drazba J, Bingaman W, Wyllie E, Wylie CJ, Yacubova K, Epilepsia, 1/1/2000
• correlated with increased N-methyl-D- receptor subunit NR2A/B in human focal cortical  
  Najm IM, Ying Z, Babb T, Mohamed A, Hadam J, LaPresto E, Wyllie E, Kotagal P, Bingaman W, Foldvary N, Morris H, Luders HO, Epilepsia, 1/1/2000
• NMDAR1 receptor proteins and mossy fibers in the fascia during rat  
  Mikuni N, Babb TL, Wylie C, Ying Z, Exp Neurol, 1/1/2000
• Decreased -NR1 co-assembly as a mechanism for focal epilepsy in cortical  
  Mikuni N, Nishiyama K, Babb TL, Ying Z, Najm I, Okamoto T, Luders HO, Wylie C, Neuroreport, 1/14/1999
• NMDA-receptors 1 and 2A/B increased in human epileptic focal cortical  
  Mikuni N, Babb TL, Ying Z, Najm I, Nishiyama K, Wylie C, Yacubova K, Okamoto T, Bingaman W, Epilepsia, 1/1/1999
• Focal cortical in children  
  Hilbig A, Babb TL, Najm I, Ying Z, Wyllie E, Bingaman W, Dev Neurosci, 1/1/1999
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Abstracts/Posters

• Therapeutic effect of lacosamide and levetiracetam in generalized seizures, as demonstrated in a rodent model of cortical dysplasia
  A. Nemes, R. O'Dwyer, Z. Ying, I. Najm, A. Alexopoulos, Epilepsy Currents, 1/1/2014
• Growth-associated protein 43, a potential substrate for progressive epileptogenesis in type ii focal cortical dysplasia
  Z. Ying, I. Najm, A. Nemes, A. Alexopoulos, Epilepsy Currents, 1/1/2014
• Increased expression of pan-trk receptor proteins in the cortex of an adult rat model of irradiation-induced cortical dysplasia
  Z. Ying, A. Nemes I. Najm, Epilepsy Currents, 1/1/2013
• Surgical pathology of intractable nonlesional focal epilepsies. which boat are we missing?
  A. Alexopoulos, I. Z. Wang, Z. Jaisani, Z. Ying, I. M. Najm, R. Prayson, Epilepsy Currents, 1/1/2013
• Increased expression of growth associated protein (gap -43) in an adult rat model of radiation-induced cortical dysplasia
  Z. Ying, i. Najm, a. Alexopoulos , c. Isitan, A. Nemes, Epilepsy Currents, 1/1/2012
• ncreased expression of growth associated protein 43 (gap-43) in human epileptic dysplastic cortex
  Z. Ying, R. O'Dwyer, Gonzalez-Martinez J, Bingaman W, and Najm I, Epilepsy Currents, 1/1/2011
• In vitro-hyperexcitability in the rat freeze lesion model of cortical dysplasia does not translate into clinical epileptogenicity
  Kellinghaus C, Moeddel G, Shigeto H, Ying Z, Jacobsson B, Burrier C, .Janigro D, and Najm I, Epilepsia 45 Suppl, 1/1/2004
• Neuronal nitric oxide synthase (nNOS) expression in dysplasitc human neocortex
  Gonzalez-Martinez J, Moeddel G, Ying Z, Bingaman W, and Najm I, Epilepsia 45 Suppl, 1/1/2004
• Neuronal nitric oxide synthase (nNOS) inhibition exerts differential anticonvulsant effects in epileptic human neocortex
  Moddel G, Gonzalez-Martinez J, Ying Z, Janigro D, Bingaman W, and Najm I, Epilepsia 45 Suppl, 1/1/2004
• Focal freeze-induced cortical dysplasia is associated with postnatal neurogenesis and focal cell migration
  Shigeto H, Boongird A, Burrier C, Jacobson B, Kellighaus C, Ying Z, I. Najm, Epilepsia 44 Suppl, 1/1/2003
• Multi-drug resistance 1 (MDR1) protein expression in Rasmussen Encephalitis
  Lardizabal D, Jacobson B, Ying Z, Bingaman W, Najm I, Epilepsia 44 Suppl, 1/1/2003
• Neurogenesis in adult human hippocampal sclerosis
  Jacobson B, Ying Z,. Burrier C, Bingaman W, Gonzalez-Martinez J, Paullin A, Staugaitis S, Prayson R, Najm I, Epilepsia 44 Suppl, 1/1/2003
• Cellular characterization of balloon cells in human cortical dysplasia
  Ying Z, Najm I, Watanabe S, Leichliter A, Boongird A, Paulson A, Bingaman W, Epilepsia 43 Suppl, 1/1/2002
• Development of NMDA Protein Subunit Coassemblies Pre- and Postnatally after E17 Gamma Irradiation-Induced Cortical Dysplasia in Rats
  Babb T.L., Mikuni N. Ying Z, Wylie C, Epilepsia 42 Suppl, 1/1/2001
• Direct Electrocorticographic and Histopathological Correlations in Focal Malformations Due to Abnormal Cortical Development
  Boonyapisit K., Najm I., Klem G., Ying Z, Bingaman W., Prayson R., Luders H, Epilepsia 42 Suppl, 1/1/2001
• Expression of NMDA Receptor Subtypes and Glutamate Transporter Proteins in Human Epileptogenic Neoplastic Tissue
  Lachhwani D.K, Ying Z, Boongird A., Wyllie E., Bingaman W., Luders H., Najm I, Epilepsia 42 Suppl, 1/1/2001
• In Vivo Spontaneous Epileptogenicity in Mice Overexpressing the Adrenergic Alpha-1 Receptor
  Boongird A.,. Kunieda T, Ying Z., Zuschik M.J., Najm I.M., Perez D., Luders H.O., Epilepsia 42 Suppl, 1/1/2001
• Increased Tyrosine Phosphorylatin of the NMDA Receptor Subunit NR2A/B in Human Epileptogenic Cortex Associated with Cortical Dysplasia
  Ying Z, Najm I, Bingaman W, Hadar E, Nair D, Luders H, Epilepsia 42 Suppl, 1/1/2001
• Regional Positron Emission Tomography (PET) Hypometabolism and Temporal Lobe Volumes (TLVs) in Patients with Intractable Temporal Lobe Epilepsy (TLE) Due to Hippocampa...
  Diehl B, Rona S, LaPresto E, Ruggieri P, Ying Z, Bingaman W, Luders H.O, Najm I, Epilepsia 42 Suppl, 1/1/2001
• Increased anchoring of NMDA 2B to PSD-95 proteins in human epileptogenic cortex associated with cortical dysplasia
  Ying Z, Najm I, Wang S, Hadar E, Nair D, Bingaman W, Luders HO, Epilepsia, 1/1/2000
• Increased expression of connexin 43 as a mechanism for human intractable cortical epilepsy
  Ying Z, Najm I, Wang S, Hadar E, Nair D, Bingaman W, Luders HO, Society of Neuroscience, 1/1/2000
• Temporal Lobe (TL) volumes in patients with temporal lobe epilepsy (TLE) due to hippocampal (HS) and cortical dysplasia (CD)
  Diehl B, Najm I, Lapresto E, Ruggieri P, Mohames A, Ying Z, Lieber M, Babb T, Bingaman W, Luders H, Epilepsia, 1/1/2000
• Epileptogenicity in focal cortical dysplasias: correlation with histopathological changes
  Najm I, Ying Z, Bingaman, W, Wang S, Babb T, Prayson R, Rona S, Nair D, Hadar E, Wyllie E, Luders H, Epilepsia, 1/1/2000
• MRI correlates of focal cortical dysplasia: A study with multimodal image analyses
  Rona S, Najm I, Ying Z, Lapresto E, Wang S, Bingaman W, Luders H, Epilepsia, 1/1/2000
• Hippocampal chemical anatomy in pediatric and adolescent patients with hippocampal or extra-hippocampal epilepsy
  Ying Z, Babb TL, Hilbig A, Wyllie E, Mohamed A, Bingaman W, Prayson R, Staugaitis S, Najm I,Luders HO, Epilepsia, 1/1/1999
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